Axon growth-promoting properties of human bone marrow mesenchymal stromal cells

Neuroscience Letters

Volumn 474, Issue 1, 2010, Pages 37-41

  Führmann, Tobias ^a   Montzka, Katrin ^a   Hillen, Lisa M ^a   Hodde, Dorothee ^a   Dreier, Agnieszka ^a   Bozkurt, Ahmet ^a   Wöltje, Michael ^a   Brook, Gary A ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Dorsal root ganglia; Human mesenchymal stromal cells; Orientation; Regeneration; Tissue culture

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; EPIDERMAL GROWTH FACTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LAMININ; NERVE GROWTH FACTOR; NEUROTROPHIN; SCATTER FACTOR; STROMAL CELL DERIVED FACTOR 1ALPHA; VASCULOTROPIN;

ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MESENCHYMAL STEM CELL; NERVE CELL; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NEURITE; PRIORITY JOURNAL; SPINAL CORD INJURY; SPINAL GANGLION; STROMA CELL;

ANIMALS; AXONS; BONE MARROW CELLS; CELLS, CULTURED; EXTRACELLULAR MATRIX; FEMALE; GANGLIA, SPINAL; HUMANS; MESENCHYMAL STEM CELLS; NEURITES; RATS; RATS, INBRED LEW;

EID: 77950930010     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.03.002     Document Type: Article

References (36)

1. Akiyama Y., Radtke C., Honmou O., Kocsis J.D. Remyelination of the spinal cord following intravenous delivery of bone marrow cells. Glia 2002, 39(3):229-236. http://dx.doi.org/10.1002/glia.10102.
2. Alluin O., Wittmann C., Marqueste T., Chabas J.-F., Garcia S., Lavaut M.-N., Guinard D., Feron F., Decherchi P. Functional recovery after peripheral nerve injury and implantation of a collagen guide. Biomaterials 2009, 30(3):363-373. http://dx.doi.org/10.1016/j.biomaterials.2008.09.043.
3. Ankeny D.P., McTigue D.M., Jakeman L.B. Bone marrow transplants provide tissue protection and directional guidance for axons after contusive spinal cord injury in rats. Exp. Neurol. 2004, 190(1):17-31. http://dx.doi.org/10.1016/j.expneurol.2004.05.045.
4. Archibald S.J., Shefner J., Krarup C., Madison R.D. Monkey median nerve repaired by nerve graft or collagen nerve guide tube. J. Neurosci. 1995, 15(5 Pt 2):4109-4123.
5. Beattie M.S., Bresnahan J.C., Komon J., Tovar C.A., Meter M.V., Anderson D.K., Faden A.I., Hsu C.Y., Noble L.J., Salzman S., Young W. Endogenous repair after spinal cord contusion injuries in the rat. Exp. Neurol. 1997, 148(2):453-463. http://dx.doi.org/10.1006/exnr.1997.6695.
6. Biran R., Noble M.D., Tresco P.A. Directed nerve outgrowth is enhanced by engineered glial substrates. Exp. Neurol. 2003, 184(1):141-152.
7. Brohlin M., Mahay D., Novikov L.N., Terenghi G., Wiberg M., Shawcross S.G., Novikova L.N. Characterisation of human mesenchymal stem cells following differentiation into schwann cell-like cells. Neurosci. Res. 2009, 64(1):41-49. http://dx.doi.org/10.1016/j.neures.2009.01.010.
8. Brook G.A., Plate D., Franzen R., Martin D., Moonen G., Schoenen J., Schmitt A.B., Noth J., Nacimiento W. Spontaneous longitudinally orientated axonal regeneration is associated with the schwann cell framework within the lesion site following spinal cord compression injury of the rat. J. Neurosci. Res. 1998, 53(1):51-65.
9. Caylan R., Bektas D., Dikmen T., Bektas O., Omay S.B., Ovali E. Mesenchymal stem cells in iatrogenic facial nerve paralysis: a possible role in the future. Eur. Arch. Otorhinolaryngol. 2006, 263(10):963-967. http://dx.doi.org/10.1007/s00405-006-0093-z.
10. Chamberlain G., Fox J., Ashton B., Middleton J. Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing. Stem Cells 2007, 25(11):2739-2749. http://dx.doi.org/10.1634/stemcells.2007-0197.
11. Delree P., Leprince P., Schoenen J., Moonen G. Purification and culture of adult rat dorsal root ganglia neurons. J. Neurosci. Res. 1989, 23(2):198-206. http://dx.doi.org/10.1002/jnr.490230210.
12. Deng Y.-B., Liu X.-G., Liu Z.-G., Liu X.-L., Liu Y., Zhou G.-Q. Implantation of bm mesenchymal stem cells into injured spinal cord elicits de novo neurogenesis and functional recovery: evidence from a study in rhesus monkeys. Cytotherapy 2006, 8(3):210-214. http://dx.doi.org/10.1080/14653240600760808.
13. Deumens R., Koopmans G.C., Bakker C.G.J.D., Maquet V., Blacher S., Honig W.M.M., Jérôme R., Pirard J.-P., Steinbusch H.W.M., Joosten E.A.J. Alignment of glial cells stimulates directional neurite growth of CNS neurons in vitro. Neuroscience 2004, 125(3):591-604. http://dx.doi.org/10.1016/j.neuroscience.2004.02.010.
14. Dezawa M. Central and peripheral nerve regeneration by transplantation of schwann cells and transdifferentiated bone marrow stromal cells. Anat. Sci. Int. 2002, 77(1):12-25. http://dx.doi.org/10.1046/j.0022-7722.2002.00012.x.
15. Dominici M., Blanc K.L., Mueller I., Slaper-Cortenbach I., Marini F., Krause D., Deans R., Keating A., Prockop D., Horwitz E. Minimal criteria for defining multipotent mesenchymal stromal cells. the international society for cellular therapy position statement. Cytotherapy 2006, 8(4):315-317. http://dx.doi.org/10.1080/14653240600855905.
16. Enzmann G.U., Benton R.L., Talbott J.F., Cao Q., Whittemore S.R. Functional considerations of stem cell transplantation therapy for spinal cord repair. J. Neurotrauma 2006, 23(3-4):479-495. http://dx.doi.org/10.1089/neu.2006.23.479.
17. Gerardo-Nava J., Führmann T., Klinkhammer K., Seiler N., Mey J., Klee D., Möller M., Dalton P.D., Brook G.A. Human neural cell interactions with orientated electrospun nanofibers in vitro. Nanomedicine 2009, 4(1):11-30. http://dx.doi.org/10.2217/17435889.4.1.11.
18. Grayson W.L., Ma T., Bunnell B. Human mesenchymal stem cells tissue development in 3D pet matrices. Biotechnol. Prog. 2004, 20(3):905-912. http://dx.doi.org/10.1021/bp034296z.
19. Guénard V., Kleitman N., Morrissey T.K., Bunge R.P., Aebischer P. Syngeneic schwann cells derived from adult nerves seeded in semipermeable guidance channels enhance peripheral nerve regeneration. J. Neurosci. 1992, 12(9):3310-3320.
20. Himes B.T., Neuhuber B., Coleman C., Kushner R., Swanger S.A., Kopen G.C., Wagner J., Shumsky J.S., Fischer I. Recovery of function following grafting of human bone marrow-derived stromal cells into the injured spinal cord. Neurorehabil. Neural Repair 2006, 20(2):278-296. http://dx.doi.org/10.1177/1545968306286976.
21. Hofstetter C.P., Schwarz E.J., Hess D., Widenfalk J., Manira A.E., Prockop D.J., Olson L. Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery. Proc. Natl. Acad. Sci. U.S.A. 2002, 99(4):2199-2204. http://dx.doi.org/10.1073/pnas.042678299.
22. Kamishina H., Cheeseman J.A., Clemmons R.M. The effects of canine bone marrow stromal cells on neuritogenesis from dorsal root ganglion neurons in vitro. Vet. Res. Commun. 2009, 33(7):645-657. http://dx.doi.org/10.1007/s11259-009-9213-8.
23. Keilhoff G., Goihl A., Stang F., Wolf G., Fansa H. Peripheral nerve tissue engineering: autologous schwann cells vs. transdifferentiated mesenchymal stem cells. Tissue Eng. 2006, 12(6):1451-1465. http://dx.doi.org/10.1089/ten.2006.12.1451.
24. Lee K.H., Suh-Kim H., Choi J.S., Jeun S.-S., Kim E.J., Kim S.-S., Yoon D.H., Lee B.H. Human mesenchymal stem cell transplantation promotes functional recovery following acute spinal cord injury in rats. Acta Neurobiol. Exp. (Wars) 2007, 67(1):13-22.
25. Luckenbill-Edds L. Laminin and the mechanism of neuronal outgrowth. Brain Res. Brain Res. Rev. 1997, 23(1-2):1-27.
26. McDonald J.W., Liu X.Z., Qu Y., Liu S., Mickey S.K., Turetsky D., Gottlieb D.I., Choi D.W. Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. Nat. Med. 1999, 5(12):1410-1412. http://dx.doi.org/10.1038/70986.
27. Milner R., Campbell I.L. Cytokines regulate microglial adhesion to laminin and astrocyte extracellular matrix via protein kinase c-dependent activation of the alpha6beta1 integrin. J. Neurosci. 2002, 22(5):1562-1572.
28. Montzka K., Lassonczyk N., Tschöke B., Neuss S., Führmann T., Franzen R., Smeets R., Brook G.A., Wöltje M. Neural differentiation potential of human bone marrow-derived mesenchymal stromal cells: misleading marker gene expression. BMC Neurosci. 2009, 10:16. http://dx.doi.org/10.1186/1471-2202-10-16.
29. Neuhuber B., Himes B.T., Shumsky J.S., Gallo G., Fischer I. Axon growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations. Brain Res. 2005, 1035(1):73-85. http://dx.doi.org/10.1016/j.brainres.2004.11.055.
30. Parr A.M., Kulbatski I., Zahir T., Wang X., Yue C., Keating A., Tator C.H. Transplanted adult spinal cord-derived neural stem/progenitor cells promote early functional recovery after rat spinal cord injury. Neuroscience 2008, 155(3):760-770. http://dx.doi.org/10.1016/j.neuroscience.2008.05.042.
31. Pfeifer K., Vroemen M., Blesch A., Weidner N. Adult neural progenitor cells provide a permissive guiding substrate for corticospinal axon growth following spinal cord injury. Eur. J. Neurosci. 2004, 20(7):1695-1704. http://dx.doi.org/10.1111/j.1460-9568.2004.03657.x.
32. Radtke C., Aizer A.A., Agulian S.K., Lankford K.L., Vogt P.M., Kocsis J.D. Transplantation of olfactory ensheathing cells enhances peripheral nerve regeneration after microsurgical nerve repair. Brain Res. 2009, 1254:10-17. http://dx.doi.org/10.1016/j.brainres.2008.11.036.
33. Ramón-Cueto A., Plant G.W., Avila J., Bunge M.B. Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants. J. Neurosci. 1998, 18(10):3803-3815.
34. Thompson D.M., Buettner H.M. Neurite outgrowth is directed by schwann cell alignment in the absence of other guidance cues. Ann. Biomed. Eng. 2006, 34(1):161-168. http://dx.doi.org/10.1007/s10439-005-9013-4.
35. Wright K.T., Masri W.E., Osman A., Roberts S., Chamberlain G., Ashton B.A., Johnson W.E.B. Bone marrow stromal cells stimulate neurite outgrowth over neural proteoglycans (cspg), myelin associated glycoprotein and nogo-a. Biochem. Biophys. Res. Commun. 2007, 354(2):559-566. http://dx.doi.org/10.1016/j.bbrc.2007.01.013.
36. Xu X.M., Chen A., Guénard V., Kleitman N., Bunge M.B. Bridging schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cord. J. Neurocytol. 1997, 26(1):1-16.