Effect of formulation parameters on the preparation of superporous hydrogel self-nanoemulsifying drug delivery system (SNEDDS) of carvedilol

AAPS PharmSciTech

Volumn 11, Issue 1, 2010, Pages 221-225

  Mahmoud, Enas Ahmed ^a   Bendas, Ehab R ^a   Mohamed, Magdy I ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Carvedilol; Self nanoemulsifying drug delivery system; Superporous hydrogel

Indexed keywords

CARVEDILOL; COPOLYMER; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; POLYACRYLAMIDE; POLYACRYLIC ACID;

ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; EMULSION; FACTORIAL DESIGN; HYDROGEL; IN VITRO STUDY; NANOPHARMACEUTICS; PLOTS AND CURVES; PRIORITY JOURNAL;

CARBAZOLES; CHEMISTRY, PHARMACEUTICAL; DOSAGE FORMS; DRUG DELIVERY SYSTEMS; HYDROGEL; PROPANOLAMINES;

EID: 77950918285     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-009-9359-2     Document Type: Article

References (11)

1. Peppas NA, Mikos AG. Hydrogels in medicine and pharmacy. Boca Raton: CRC; 1986.
2. Park K. Superporous hydrogels for pharmaceutical & other applications; 2002. http://www.drugdeliverytech.com/cgi-bin/articles.cgi? idArticle=60.
3. J Kroupova D Horak J Pachernik P Dvorak M Slouf 2006 Functional polymer hydrogels for embryonic stem cell support J Biomed Mater Res B Appl Biomater 76 2 315 25 16080172
4. FA Dorkoosh CA Broekhuizen G Borchard M Rafiee-Tehrani JC Verhoef HE Junginger 2004 Transport of octreotide and evaluation of mechanism of opening the paracellular tight junctions using superporous hydrogel polymers in Caco-2 cell monolayers J Pharm Sci 93 3 743 52 10.1002/jps.10570 1:CAS:528: DC%2BD2cXitV2lsbY%3D 14762912 (Pubitemid 38332306)
5. Ratner BD, Hoffman AS. Synthetic hydrogels for biomedical applications. Washington: American Chemical Society; 1976.
6. H Omidian JG Rocca K Park 2006 Elastic, superporous hydrogel hybrids of polyacrylamide and sodium alginate Macromol Biosci 6 9 703 10 10.1002/mabi.200600062 1:CAS:528:DC%2BD28XhtVClurrL 16967483 (Pubitemid 44544929)
7. Kabra BG, Gehrke SH. Rate-limiting steps for solvent sorption and desorption by microporous stimuli-sensitive absorbent gels. Washington: American Chemical Society; 1994.
8. J Chen H Park K Park 1999 Synthesis of superporous hydrogels: hydrogels with fast swelling and superabsorbent properties J Biomed Mater Res 44 1 53 62 10.1002/(SICI)1097-4636(199901)44:1<53::AID-JBM6>3.0.CO;2-W 1:CAS:528:DyaK1cXnvFeltr0%3D 10397904
9. Y Qiu K Park 2003 Superporous IPN hydrogels having enhanced mechanical properties AAPS PharmSciTech 4 4 E51 10.1208/pt040451 15198546
10. J Chen K Park 2000 Synthesis and characterization of superporous hydrogel composites J Control Release 65 1-2 73 82 10.1016/S0168-3659(99)00238-2 1:CAS:528:DC%2BD3cXhtl2qsrc%3D 10699272 (Pubitemid 30122917)
11. G Di Colo A Baggiani Y Zambito G Mollica M Geppi MF Serafini 2006 A new hydrogel for the extended and complete prednisolone release in the GI tract Int J Pharm 310 1-2 154 61 16414222