Assessment of regional variation in polypharmacy

Pharmacoepidemiology and Drug Safety

Volumn 19, Issue 4, 2010, Pages 375-383

  Hovstadius, Bo ^a,b   Åstrand, Bengt ^a   Petersson, Göran ^a  

^a LINNAEUS UNIVERSITY   (Sweden)

^b Mergers and Acquisitions Group   (Sweden)

Author keywords

Drug prescribing; Drug utilisation; Polypharmacy

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; COMPARATIVE STUDY; CORRELATION ANALYSIS; DRUG UTILIZATION; FEMALE; GROUPS BY AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; PHARMACOEPIDEMIOLOGY; POLYPHARMACY; PRESCRIPTION; PREVALENCE; PRIORITY JOURNAL; SOCIOECONOMICS; SWEDEN;

ADULT; AGE DISTRIBUTION; AGE FACTORS; AGED; AGED, 80 AND OVER; DRUG UTILIZATION REVIEW; FEMALE; HUMANS; MALE; MIDDLE AGED; PHYSICIAN'S PRACTICE PATTERNS; POLYPHARMACY; PRESCRIPTION DRUGS; SEX FACTORS; SOCIOECONOMIC FACTORS; SWEDEN; YOUNG ADULT;

EID: 77950874919     PISSN: 10538569     EISSN: 10991557     Source Type: Journal    
DOI: 10.1002/pds.1921     Document Type: Article

References (33)

1. Kaufman DW, Kelly JP, Rosenberg L, Anderson TE, Mitchell AA. Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey. JAMA 2002; 287: 337-344. (Pubitemid 34251967)
2. Astrand B, Hovstadius B, Antonov K, Petersson G. The Swedish national pharmacy register. Stud Health Technol Inform 2007; 129: 345-349.
3. Klarin I, Wimo A, Fastbom J. The association of inappropriate drug use with hospitalisation and mortality: a population-based study of the very old. Drugs Aging 2005; 22: 69-82. (Pubitemid 40188906)
4. Bjerrum L, Sogaard J, Hallas J, Kragstrup J. Polypharmacy: correlations with sex, age and drug regimen. A prescription database study. Eur J Clin Pharmacol 1998; 54: 197-202.
5. Apoteket AB. [Swedish National Corporation of Pharmacies] Total AUP och DDD 1985-2005. http://www2.apoteket.se/NR/rdonlyres/2AAC60FD-BA94-447B-98E3- 7A64D995FF45/0/Inlev19852005.pdf [accessed 7 January 2009].
6. Apoteket AB. [Swedish National Corporation of Pharmacies] Läkemedelsutveckling 2007. http://www2.apoteket.se/NR/rdonlyres/F6816CEA- 6B1F- 4338-9483-A03AF97BA32E/0/Årsrapportny080519.pdf [accessed 7 January 2009].
7. Colley CA, Lucas LM. Polypharmacy: the cure becomes the disease. J Gen Intern Med 1993; 8: 278-283.
8. World Health Organisation. Rational use of medicines by prescribers and patients. Report by the Secretariat, EB 118/6, May 2006.
9. Salazar JA, Poon I, Nair M. Clinical consequences of polypharmacy in elderly: expect the unexpected, think the unthinkable. Expert Opin Drug Saf 2007; 6: 695-704. (Pubitemid 351308281)
10. Steinman MA, Landefeld CS, Rosenthal GE, Berthenthal D, Sen S, Kaboli PJ. Polypharmacy and prescribing quality in older people. J Am Geriatr Soc 2006; 54: 1516-1523. (Pubitemid 44564145)
11. Gorard DA. Escalating polypharmacy. QJM 2006; 99: 797-800.
12. Rossi MI, Young A, Maher R, et al. Polypharmacy and health beliefs in older outpatients. Am J Geriatr Pharmacother 2007; 5: 317-323.
13. Linjakumpu T, Hartikainen S, Klaukka T, Veijola J, Kivelä SL, Isoaho R. Use of medications and polypharmacy are increasing among the elderly. J Clin Epidemiol 2002; 55: 809-817.
14. Hajjar ER, Cafiero AC, Hanlon JT. Polypharmacy in elderly patients. Am J Geriatr Pharmacother 2007; 5: 345-351.
15. Haider SI, Johnell K, Thorslund M, Fastbom J. Trends in polypharmacy and potential drug-drug interactions across educational groups in elderly patients in Sweden for the period. 1992-2002. Int J Clin Pharmacol Ther 2007; 45: 643-653.
16. Veehof L, Stewart R, Haaijer-Ruskamp F, Meyboom-de Jong B. The development of polypharmacy. A longitudinal study. Fam Pract 2000; 17: 261-267.
17. Hoven JL, Haaijer-Ruskamp FM, Vander Stichele RH. Indicators of prescribing quality in drug utilisation research: report of a European meeting (DURQUIM. 13-15 May 2004). Eur J Clin Pharmacol 2005; 60: 831-834.
18. The National Board of Health and Welfare. Pharmaceuticals - Statistics for 2006, Stockholm, 2007.
19. Wettermark B, Hammar N, Fored CM, et al. The new Swedish prescribed drug register - opportunities for pharmacoepidemiological research and experience from the first six months. Pharmacoepidemiol Drug Saf 2007; 16: 726-735. (Pubitemid 47180362)
20. World Health Organisation. A Glossary of Terms for Community Health Care and Services for Older Persons. World Health Organisation Centre for Health Development, 2004.
21. Hovstadius B, Astrand B, Petersson G. Dispensed drugs and multiple medications in the Swedish population: an individual-based register study. BMC Clin Pharmacol 2009; 9: 11.
22. Viktil KK, Blix HS, Moger TA, Reikvam A. Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug-related problems. Br J Clin Pharmacol 2007; 63: 187-195. (Pubitemid 46072105)
23. Aronson JK. Polypharmacy, appropriate and inappropriate. Br J Gen Pract 2006; 56: 484-485.
24. Haider SI, Johnell K, Weitoft GR, Thorslund M, Fastbom J. The influence of educational level on polypharmacy and inappropriate drug use: a register-based study of more than 600,000 older people. J Am Geriatr Soc 2009; 57: 62-69.
25. Bjerrum L. Pharmacoepidemiological Studies of Polypharmacy: Methodological Issues, Population Estimates, and Influence of Practice Patterns. Odense University Denmark: Odense, 1998.
26. Nguyen JK, Fouts MM, Kotabe SE, Lo E. Polypharmacy as a risk factor for adverse drug reactions in geriatric nursing home residents. Am J Geriatr Pharmacother 2006; 4: 36-41. (Pubitemid 43758180)
27. Onder G, Pedone C, Landi F, et al. Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). J Am Geriatr Soc 2002; 50: 1962-1968.
28. Hanlon JT, Artz MB, Pieper CF, et al. Inappropriate medication use among frail elderly inpatients. Ann Pharmacother 2004; 38: 9-14. (Pubitemid 38017997)
29. Swedish Institute for Infections Disease Control. SWEDRES 2006 A Report on Swedish Antibiotic Utilisation and Resistance in Human Medicine. Stockholm, 2006.
30. Jamtvedt G, Young JM, Kristoffersen DT, O'Brien MA, Oxman AD. Audit and feedback: effects on professional practice and health care outcomes. Cochrane Database Syst Rev 2006; CD000259.
31. Hanlon JT, Schmader KE, Samsa GP, et al. A method for assessing drug therapy appropriateness. J Clin Epidemiol 1992; 45: 1045-1051.
32. Samsa GP, Hanlon JT, Schmader KE, et al. A summated score for the medication appropriateness index: development and assessment of clinimetric properties including content validity. J Clin Epidemiol 1994; 47: 891-896.
33. Campbell SM, Braspenning J, Hutchinson A, Marshall M. Research methods used in developing and applying quality indicators in primary care. Qual Saf Health Care 2002; 11: 358-364. (Pubitemid 35463394)