Serum protein profiling and proteomics in autistic spectrum disorder using magnetic bead-assisted mass spectrometry

European Archives of Psychiatry and Clinical Neuroscience

Volumn 260, Issue 3, 2010, Pages 249-255

  Taurines, Regina ^a   Dudley, Edward ^b   Conner, Alexander C ^a   Grassl, Julia ^a   Jans, Thomas ^c   Guderian, Frank ^c   Mehler Wex, Claudia ^d   Warnke, Andreas ^c   Gerlach, Manfred ^c   Thome, Johannes ^a  

^a SWANSEA UNIVERSITY   (United Kingdom)

^b SWANSEA UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF ULM   (Germany)

Author keywords

Autism; Biomarker discovery; Proteomics; Serum profiling

Indexed keywords

BIOLOGICAL MARKER; PLASMA PROTEIN;

ADOLESCENT; ADULT; AGE DISTRIBUTION; ARTICLE; ATTENTION DEFICIT DISORDER; AUTISM; CHILD; CLINICAL ARTICLE; COMORBIDITY; COMPUTER PROGRAM; HUMAN; INFORMATION PROCESSING; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; PSYCHOMETRY; SCHOOL CHILD; SEX DIFFERENCE;

ADOLESCENT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; AUTISTIC DISORDER; BIOLOGICAL MARKERS; BLOOD PROTEINS; CASE-CONTROL STUDIES; CHILD; COMPUTATIONAL BIOLOGY; HUMANS; MALE; NEUROPSYCHOLOGICAL TESTS; PROTEIN ARRAY ANALYSIS; PROTEOMICS; PSYCHOMETRICS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 77950865808     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00406-009-0066-5     Document Type: Article

References (45)

1. TM Achenbach CS Edelbrock 1981 Behavioural problems and competencies reported by parents of normal and disturbed children aged four through sixteen Monogr Soc Res Child Dev 46 1 1 82 10.2307/1165983 1:STN:280: DyaL3M3itVKrtw%3D%3D 7242540
2. MK Belmonte EH Cook Jr GM Anderson JL Rubenstein WT Greenough A Beckel-Mitchener E Courchesne LM Boulanger SB Powell PR Levitt EK Perry YH Jiang TM DeLorey E Tierney 2004 Autism as a disorder of neural information processing: directions for research and targets for therapy Mol Psychiatry 9 7 646 663 1:CAS:528:DC%2BD2cXltFWntL0%3D 15037868 (Pubitemid 38932171)
3. Boelte S (2006) PF. FSK-Fragebogen zur Sozialen Kommunikation. Huber, Bern
4. Boelte SRD, Schmoetzer G, Poustka F (2006) ADI-R-Diagnostisches Interview fuer Autismus - Revidiert. Huber, Bern
5. AJ Cheng LC Chen KY Chien YJ Chen JT Chang HM Wang CT Liao IH Chen 2005 Oral cancer plasma tumor marker identified with bead-based affinity-fractionated proteomic technology Clin Chem 51 12 2236 2244 10.1373/clinchem.2005.052324 1:CAS:528:DC%2BD2MXht1yks7fO 16239339 (Pubitemid 41692565)
6. EH Cook BL Leventhal 1996 The serotonin system in autism Curr Opin Pediatr 8 4 348 354 10.1097/00008480-199608000-00008 1:STN:280: DyaK2s7pslCqtQ%3D%3D 9053096
7. EH Cook Jr BL Leventhal W Heller J Metz M Wainwright DX Freedman 1990 Autistic children and their first-degree relatives: relationships between serotonin and norepinephrine levels and intelligence J Neuropsychiatry Clin Neurosci 2 3 268 274 2136085 (Pubitemid 20312481)
8. BA Corbett AB Kantor H Schulman WL Walker L Lit P Ashwood DM Rocke FR Sharp 2007 A proteomic study of serum from children with autism showing differential expression of apolipoproteins and complement proteins Mol Psychiatry 12 3 292 306 1:CAS:528:DC%2BD2sXitFCiur4%3D 17189958 (Pubitemid 46328511)
9. AM Coutinho G Oliveira T Morgadinho C Fesel TR Macedo C Bento C Marques A Ataide T Miguel L Borges AM Vicente 2004 Variants of the serotonin transporter gene (SLC6A4) significantly contribute to hyperserotonemia in autism Mol Psychiatry 9 3 264 271 10.1038/sj.mp.4001409 1:CAS:528:DC%2BD2cXhvFCmsLs%3D 15094787 (Pubitemid 38496717)
10. J Croonenberghs L Delmeire R Verkerk AH Lin A Meskal H Neels M Van der Planken S Scharpe D Deboutte G Pison M Maes 2000 Peripheral markers of serotonergic and noradrenergic function in post-pubertal, caucasian males with autistic disorder Neuropsychopharmacology 22 3 275 283 10.1016/S0893-133X(99) 00131-1 1:CAS:528:DC%2BD3cXhtFagtLo%3D 10693155 (Pubitemid 30089538)
11. P D'Eufemia R Finocchiaro M Celli L Viozzi D Monteleone O Giardini 1995 Low serum tryptophan to large neutral amino acids ratio in idiopathic infantile autism Biomed Pharmacother 49 6 288 292 10.1016/0753-3322(96)82645-X 7579010
12. ME de Noo A Deelder M van der Werff A Ozalp B Mertens R Tollenaar 2006 MALDI-TOF serum protein profiling for the detection of breast cancer Onkologie 29 11 501 506 10.1159/000095933 17068384 (Pubitemid 44631671)
13. ME de Noo BJ Mertens A Ozalp MR Bladergroen MP van der Werff CJ van de Velde AM Deelder RA Tollenaar 2006 Detection of colorectal cancer using MALDI-TOF serum protein profiling Eur J Cancer 42 8 1068 1076 10.1016/j.ejca.2005.12.023 16603345
14. B Devlin EH Cook Jr H Coon G Dawson EL Grigorenko W McMahon N Minshew D Pauls M Smith MA Spence PM Rodier C Stodgell GD Schellenberg 2005 Autism and the serotonin transporter: the long and short of it Mol Psychiatry 10 12 1110 1116 10.1038/sj.mp.4001724 1:CAS:528:DC%2BD2MXht1Ghu77E 16103890 (Pubitemid 43251101)
15. MP Ebert D Niemeyer SO Deininger T Wex C Knippig J Hoffmann J Sauer W Albrecht P Malfertheiner C Rocken 2006 Identification and confirmation of increased fibrinopeptide a serum protein levels in gastric cancer sera by magnet bead assisted MALDI-TOF mass spectrometry J Proteome Res 5 9 2152 2158 10.1021/pr060011c 1:CAS:528:DC%2BD28Xnt12nurk%3D 16944926 (Pubitemid 44330807)
16. K Hashimoto Y Iwata K Nakamura M Tsujii KJ Tsuchiya Y Sekine K Suzuki Y Minabe N Takei M Iyo N Mori 2006 Reduced serum levels of brain-derived neurotrophic factor in adult male patients with autism Prog Neuropsychopharmacol Biol Psychiatry 30 8 1529 1531 10.1016/j.pnpbp.2006.06.018 1:CAS:528: DC%2BD28XhtFCjsLbK 16876305 (Pubitemid 44634961)
17. H Jyonouchi S Sun H Le 2001 Proinflammatory and regulatory cytokine production associated with innate and adaptive immune responses in children with autism spectrum disorders and developmental regression J Neuroimmunol 120 1-2 170 179 10.1016/S0165-5728(01)00421-0 1:CAS:528:DC%2BD3MXnvFKjt7Y%3D 11694332 (Pubitemid 33016737)
18. Kaufman AS, Kaufman NL (1983) K-ABC interpretive manual. American Guidance Service, Circle Pines
19. Kaufman AS, Kaufman NL (1983) K-ABC administration and scoring manual. American Guidance Service, Circle Pines
20. TL Kemper ML Bauman 2002 Neuropathology of infantile autism Mol Psychiatry 7 Suppl 2 S12 S13 10.1038/sj.mp.4001165 12142934
21. CR Lake MG Ziegler DL Murphy 1977 Increased norepinephrine levels and decreased dopamine-beta-hydroxylase activity in primary autism Arch Gen Psychiatry 34 5 553 556 1:CAS:528:DyaE2sXkt1Sgs7o%3D 558741
22. JM Launay C Bursztejn P Ferrari C Dreux A Braconnier E Zarifian S Lancrenon J Fermanian 1987 Catecholamines metabolism in infantile autism: a controlled study of 22 autistic children J Autism Dev Disord 17 3 333 347 10.1007/BF01487064 1:STN:280:DyaL1c%2Fgslaltw%3D%3D 3654486
23. BL Leventhal EH Cook Jr M Morford A Ravitz DX Freedman 1990 Relationships of whole blood serotonin and plasma norepinephrine within families J Autism Dev Disord 20 4 499 511 10.1007/BF02216055 1:STN:280:DyaK3M7itlWlsg%3D%3D 2279970
24. C Lord M Rutter S Goode J Hemsbergen H Jordan L Mawhood E Schopler 1989 Autism diagnostic observation schedule: a standardized observation of communicative and social behavior J Autism Dev Disord 19 2 185 212 10.1007/BF02211841 1:STN:280:DyaL1MzgvVGisw%3D%3D 2745388 (Pubitemid 19176529)
25. C Lord M Rutter A Le Couteur 1994 Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders J Autism Dev Disord 24 5 659 685 10.1007/BF02172145 1:STN:280:DyaK2M7htlOlsg%3D%3D 7814313 (Pubitemid 24309810)
26. G Malik MD Ward SK Gupta MW Trosset WE Grizzle BL Adam JI Diaz OJ Semmes 2005 Serum levels of an isoform of apolipoprotein A-II as a potential marker for prostate cancer Clin Cancer Res 11 3 1073 1085 1:CAS:528:DC%2BD2MXht1yntrY%3D 15709174 (Pubitemid 40175756)
27. PA McBride GM Anderson ME Hertzig ME Snow SM Thompson VD Khait T Shapiro DJ Cohen 1998 Effects of diagnosis, race, and puberty on platelet serotonin levels in autism and mental retardation J Am Acad Child Adolesc Psychiatry 37 7 767 776 10.1097/00004583-199807000-00017 1:STN:280:DyaK1czjtFSrsQ%3D%3D 9666633 (Pubitemid 28304541)
28. K Miyazaki N Narita R Sakuta T Miyahara H Naruse N Okado M Narita 2004 Serum neurotrophin concentrations in autism and mental retardation: a pilot study Brain Dev 26 5 292 295 10.1016/S0387-7604(03)00168-2 15165668 (Pubitemid 38692430)
29. CA Molloy AL Morrow J Meinzen-Derr K Schleifer K Dienger P Manning-Courtney M Altaye M Wills-Karp 2006 Elevated cytokine levels in children with autism spectrum disorder J Neuroimmunol 172 1-2 198 205 10.1016/j.jneuroim.2005.11.007 1:CAS:528:DC%2BD28XhvVWgsr4%3D 16360218 (Pubitemid 43277506)
30. R Muhle SV Trentacoste I Rapin 2004 The genetics of autism Pediatrics 113 5 e472 e486 10.1542/peds.113.5.e472 15121991
31. MG Naffah-Mazzacoratti R Rosenberg MJ Fernandes CM Draque W Silvestrini L Calderazzo EA Cavalheiro 1993 Serum serotonin levels of normal and autistic children Braz J Med Biol Res 26 3 309 317 1:STN:280:DyaK2c%2FotVWrtA%3D%3D 8257930
32. KB Nelson JK Grether LA Croen JM Dambrosia BF Dickens LL Jelliffe RL Hansen TM Phillips 2001 Neuropeptides and neurotrophins in neonatal blood of children with autism or mental retardation Ann Neurol 49 5 597 606 10.1002/ana.1024 1:CAS:528:DC%2BD3MXjvFKhu7c%3D 11357950 (Pubitemid 32429787)
33. PG Nelson T Kuddo EY Song JM Dambrosia S Kohler G Satyanarayana C Vandunk JK Grether KB Nelson 2006 Selected neurotrophins, neuropeptides, and cytokines: developmental trajectory and concentrations in neonatal blood of children with autism or Down syndrome Int J Dev Neurosci 24 1 73 80 10.1016/j.ijdevneu.2005. 10.003 1:CAS:528:DC%2BD28XhvVWgu7c%3D 16289943 (Pubitemid 43287950)
34. K Okada K Hashimoto Y Iwata K Nakamura M Tsujii KJ Tsuchiya Y Sekine S Suda K Suzuki G Sugihara H Matsuzaki T Sugiyama M Kawai Y Minabe N Takei N Mori 2007 Decreased serum levels of transforming growth factor-beta1 in patients with autism Prog Neuropsychopharmacol Biol Psychiatry 31 1 187 190 10.1016/j.pnpbp.2006.08.020 1:CAS:528:DC%2BD2sXht1antA%3D%3D 17030376 (Pubitemid 44959274)
35. F Polleux JM Lauder 2004 Toward a developmental neurobiology of autism Ment Retard Dev Disabil Res Rev 10 4 303 317 10.1002/mrdd.20044 15666334 (Pubitemid 40209463)
36. Ruehl D, Feineis-Matthews S, Poustka F (2004) ADOS-Diagnostische Beobachtungsskala fuer Autistische Stoerungen. Huber, Bern
37. Rutter M, Bailey A, Berument SK, Le Couteur A, Lord C, Pickles A (2003) Social communication questionnaire (SCQ). Western Psychological Services, Los Angeles
38. C Schmitz P Rezaie 2007 The neuropathology of autism: where do we stand? Neuropathol Appl Neurobiol 34 4 11 17971078
39. VK Singh RP Warren JD Odell P Cole 1991 Changes of soluble interleukin-2, interleukin-2 receptor, T8 antigen, and interleukin-1 in the serum of autistic children Clin Immunol Immunopathol 61 3 448 455 10.1016/S0090-1229(05)80015-7 1:STN:280:DyaK38%2FjsFOltA%3D%3D 1934632
40. Snijders JT, Tellegen PJ, Laros JA (1989) Snijders-Oomen Nonverbal Intelligence Test, SON-R. Manual & Research Report Lisse. Swets & Zeitlinger, Amsterdam
41. Tewes U, Rossmann P, Schallberger U (1999) Hamburg-Wechsler- Intelligenztest für Kinder (HAWIK III). Hans Huber, Bern
42. RS Tirumalai KC Chan DA Prieto HJ Issaq TP Conrads TD Veenstra 2003 Characterization of the low molecular weight human serum proteome Mol Cell Proteomics 2 10 1096 1103 10.1074/mcp.M300031-MCP200 1:CAS:528: DC%2BD3sXovFWmt7s%3D 12917320
43. RP Warren VK Singh 1996 Elevated serotonin levels in autism: association with the major histocompatibility complex Neuropsychobiology 34 2 72 75 10.1159/000119295 1:STN:280:DyaK2s%2FmtVKruw%3D%3D 8904735
44. H Zhang B Kong X Qu L Jia B Deng Q Yang 2006 Biomarker discovery for ovarian cancer using SELDI-TOF-MS Gynecol Oncol 102 1 61 66 10.1016/j.ygyno. 2005.11.029 1:CAS:528:DC%2BD28XlsFCntrc%3D 16403569 (Pubitemid 43851051)
45. AW Zimmerman H Jyonouchi AM Comi SL Connors S Milstien A Varsou MP Heyes 2005 Cerebrospinal fluid and serum markers of inflammation in autism Pediatr Neurol 33 3 195 201 10.1016/j.pediatrneurol.2005.03.014 16139734 (Pubitemid 41558217)