Randomized trial of buccal versus vaginal misoprostol for induction of second trimester abortion

Contraception

Volumn 81, Issue 5, 2010, Pages 441-445

  Ellis, Sacheen Carr ^a   Kapp, Nathalie ^a   Vragpvoc, Olivera ^a   Borgata, Lynn ^a  

^a BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Buccal misoprostol; Induced abortion; Misoprostol; Randomized control trial; Second trimester

Indexed keywords

MISOPROSTOL; MORPHINE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG EFFICACY; FEMALE; GESTATIONAL AGE; HOSPITAL ADMISSION; HUMAN; INDUCED ABORTION; LABOR INDUCTION; LABOR PAIN; NAUSEA; PATIENT ATTITUDE; PATIENT CONTROLLED ANALGESIA; PREGNANCY TERMINATION; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SECOND TRIMESTER ABORTION; VOMITING;

ABORTIFACIENT AGENTS, NONSTEROIDAL; ABORTION, INDUCED; ADMINISTRATION, INTRAVAGINAL; ADMINISTRATION, ORAL; ADULT; FEMALE; HUMANS; MISOPROSTOL; PREGNANCY; PREGNANCY TRIMESTER, SECOND; PROSPECTIVE STUDIES; YOUNG ADULT;

EID: 77950865571     PISSN: 00107824     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.contraception.2009.12.018     Document Type: Article

References (17)

1. Kapp N., and von Hertzen H. Medical methods to induce abortion in the second trimester. In: Paul M., Lichtenberg E.S., Borgatta L., Grimes D., Stubblefield P., and Creinin M. (Eds). A clinician's guide to medical and surgical abortion (2009), Blackwell Publishing Ltd, United Kingdom 178-192
2. Dickinson J.E., and Evans S.F. The optimization of intravaginal misoprostol dosing schedules in second-trimester pregnancy termination. Am J Obstet and Gynecol 1186 (2002) 470-474
3. Ramin K.D. High-dose oral misoprostol for mid-trimester pregnancy interruption. Gynecol Obstet Invest 54 (2002) 176-179
4. Ngai S.W., Tang O.S., and HO P.C. Randomization comparison of vaginal (200 microg every 3 h) and oral (400 microg every 3 h) misoprostol when combined with mifepristone in termination of second trimester pregnancy. Hum Reprod 15 (2000) 2205-2208
5. Zieman M., Fong S.K., Benowitz N.L., et al. Absorption kinetics of misoprostol with oral or vaginal administration. Obstet Gynecol 90 (1997) 88-92
6. Danielsson K.G., Marions L., Rodriguez A., et al. Comparison between oral and vaginal administration of misoprostol on uterine contractility. Obstet Gynecol 93 (1999) 275-279
7. Gilbert A. A randomized trial of oral versus vaginal administration of misoprostol for the purpose of mid-trimester termination of pregnancy. Aust NZ J Obstet Gynecol 41 (2001) 407-410
8. Bebbington M.W., Kent N., Lim K., et al. A randomized controlled trial comparing two protocols for the use of misoprostol inmidtrimester pregnancy termination. Am J Obstet Gynecol 187 (2002) 853-857
9. Fisher S.A., Mackenzie V.P., and Davies G.A. Oral versus vaginal misoprostol for induction of labor: a double-blind randomized controlled trial. Am J Obstet Gynecol 185 (2001) 906-910
10. Middleton T., Schaff E., Fielding S.L., et al. Randomized trial of mifepristone and buccal or vaginal misoprostol for abortion through 56 days of last menstrual period. Contraception 72 (2005) 328-332
11. Todd C.S. Buccal misoprostol as cervical preparation for second trimester pregnancy termination. Contraception 65 (2002) 415-418
12. Carlan S.J. Buccal versus intravaginal misoprostol administration for cervical ripening. Am J Obstet Gynecol 186 (2002) 229-233
13. Patel A., Talmont E., Morfesis J., et al. Planned parenthood federation of America buccal misoprostol waiver group. Adequacy and safety of buccal misoprostol for cervical preparation prior to termination of second-trimester pregnancy. Contraception 73 (2006) 420-430
14. Jackson R.A., Teplin V.L., Drey E.A., et al. Digoxin to facilitate late second trimester abortion: a randomized, masked, placebo-controlled trial. Obstet Gynecol 97 (2001) 471-476
15. Feldman D.M., Borgida A.F., Rodis J.F., et al. A randomized comparison of two regimens of misoprostol for second-trimester pregnancy termination. Am J Obstet Gynecol 189 (2003) 710-713
16. El-Refaey H., and Templeton A. Pregnancy: induction of abortion in the second trimester combination of misoprostol and mifepristone: a randomized comparison between two misoprostol regimens. Hum Reprod 10 (1995) 475-478
17. Dickinson J.E., and Evans S.F. A comparison of oral misoprostol with vaginal misoprostol administration in second-trimester pregnancy termination for fetal anomaly. Obstet Gynecol 101 (2003) 1294-1299