Comparison between oral and vaginal administration of misoprostol on uterine contractility

Obstetrics and Gynecology

Volumn 93, Issue 2, 1999, Pages 275-280

  Danielsson, K Gemzell ^a,b   Marions, L ^a,b   Rodriguez, A ^a,b   Spur, B W ^a,b   Wong, P Y K ^a,b   Bygdeman, M ^a,b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MISOPROSTOL;

ADULT; ARTICLE; CLINICAL ARTICLE; CURETTAGE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG EFFICACY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTRAVAGINAL DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; PREGNANCY TERMINATION; PRIORITY JOURNAL; UTERUS CONTRACTION;

ABORTIFACIENT AGENTS, NONSTEROIDAL; ABORTION, INDUCED; ADMINISTRATION, INTRAVAGINAL; ADMINISTRATION, ORAL; ADULT; FEMALE; HUMANS; MISOPROSTOL; PREGNANCY; TIME FACTORS; UTERINE CONTRACTION;

EID: 0033081990     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0029-7844(98)00436-0     Document Type: Article

References (17)

1. Norman J.E., Thong K.J., Baird D.T. Uterine contractility and induction of abortion in early pregnancy by misoprostol and mifepristone. Lancet. 338:1991;1233-1236.
2. Aubeny E., Baulieu E.E. Activité contragestive de l'association au RU 486 d'une prostaglandin active par voie orale. C R Acad Sci (Paris). 312:1991;539-545.
3. McKinley C., Thong K.J., Baird D.T. The effect of dose of mifepristone and gestation on efficacy of medical abortion with mifepristone and misoprostol. Hum Reprod. 8:1993;1502-1505.
4. Baird D.T., Sukcharven N., Thong K.J. Randomized trial of misoprostol and Cervagem in combination with a reduced dose of mifepristone for induction of labour. Hum Reprod. 10:1995;1521-1527.
5. 2 for termination of second trimester pregnancy. N Engl J Med. 331:1994;290-293.
6. Bugalho A., Bique C., Machungo F., Faundes A. Low-dose vaginal misoprostol for induction of labor with a live fetus. Int J Gynaecol Obstet. 49:1995;149-155.
7. Wing D.A., Rakall A., Jones M.M., Goodwin T.M., Paul R.H. Misoprostol An effective agent for cervical ripening and labor induction . Am J Obstet Gynecol. 172:1995;1811-1816.
8. 2 in term pregnancy. Int J Gynaecol Obstet. 55:1996;99-104.
9. Toppozada M.K., Anwar M.Y.M., Hassan H.A., El-Gazaerly W.S. Oral or vaginal misoprostol for induction of labor. Int J Gynaecol Obstet. 56:1997;135-139.
10. Creinin M.D., Vittinghoff E., Galbraith S., Klaisle C. A randomized trial comparing misoprostol three and ten days after methotrexate for early abortion. Am J Obstet Gynecol. 173:1995;1578-1584.
11. Zieman M., Fong S.K., Benowitz N.L., Banskter D., Darney P.D. Absorption kinetics of misoprostol with oral or vaginal administration. Obstet Gynecol. 90:1997;88-92.
12. Caldeyro-Barcia R., Poseiro J.J. Oxytocin and contractility of the human pregnant uterus. Ann N Y Acad Sci. 75:1959;813-830.
13. Snedecor G.W., Cochran W.G. Statistical methods. 6th ed. 1973;State University Press, Ames, Iowa.
14. Bygdeman M., Swahn M.L. Progesterone receptor blockage. Effect on uterine contractility in early pregnancy. Contraception. 32:1985;45-51.
15. Swahn M.L., Bygdeman M. The effect of the antiprogestin RU 486 on uterine contractility and sensitivity to prostaglandin and oxytocin. Br J Obstet Gynaecol. 95:1988;126-134.
16. Bugalho A., Bique C., Almeida L., Faundes A. The effectiveness of intravaginal misoprostol (Cytotec) in inducing abortion after eleven weeks of pregnancy. Stud Fam Plann. 24:1993;319-323.
17. El-Refaey H., Templeton A.A. Early induction of abortion by a combination of mifepristone and misoprostol by the vaginal route. Contraception. 49:1993;111-114.