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Volumn 17, Issue 7, 2010, Pages 494-499

Double-blind, placebo-controlled, randomised study of single dose effects of ADAPT-232 on cognitive functions

Author keywords

Accuracy; Adaptogens; Attention; Eleutherococcus senticosus; Mental performance; Rhodiola rosea; Schisandra chinensis; Speed

Indexed keywords

ADAPT 232; HERBACEOUS AGENT; PLACEBO; UNCLASSIFIED DRUG;

EID: 77950858131     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2010.02.005     Document Type: Article
Times cited : (46)

References (21)
  • 1
    • 77950864253 scopus 로고
    • Experimental trials of phytoadaptogen effect on the quality of operators' activity, mental and physical working capacity
    • Institute of Medical and Biological Problems IMBP, Moscow, pp
    • Bogatova, R.I., Shlyakova, L.V., Malozemov, V.V., Narinskaja, A.L., Roslyakova, N.A., Shangin, A.L., 1994. Experimental trials of phytoadaptogen effect on the quality of operators' activity, mental and physical working capacity. Final Report on ADAPT 232. Institute of Medical and Biological Problems (IMBP), Moscow, pp. 1-151.
    • (1994) Final Report on ADAPT , vol.232 , pp. 1-151
    • Bogatova, R.I.1    Shlyakova, L.V.2    Malozemov, V.V.3    Narinskaja, A.L.4    Roslyakova, N.A.5    Shangin, A.L.6
  • 2
    • 0031297030 scopus 로고    scopus 로고
    • Evaluation of the effect of a single dose of a phytoadaptogen on human subjects' work ability during long isolation
    • Bogatova R.I., Shlyakova L.V., Salnitsky V.P., and Wikman G. Evaluation of the effect of a single dose of a phytoadaptogen on human subjects' work ability during long isolation. Aerospace Environ. Med. 31 (1997) 51-54
    • (1997) Aerospace Environ. Med. , vol.31 , pp. 51-54
    • Bogatova, R.I.1    Shlyakova, L.V.2    Salnitsky, V.P.3    Wikman, G.4
  • 3
    • 0014463631 scopus 로고
    • New substances of plant origin which increase non-specific resistance
    • Brekhman I.I., and Dardymov I.V. New substances of plant origin which increase non-specific resistance. Annu. Rev. Pharmacol. 9 (1969) 419-430
    • (1969) Annu. Rev. Pharmacol. , vol.9 , pp. 419-430
    • Brekhman, I.I.1    Dardymov, I.V.2
  • 5
    • 0036182303 scopus 로고    scopus 로고
    • Eleutherococcus senticosus reduces cardiovascular stress response in healthy subjects: a randomized, placebo-controlled trial
    • Facchinetti F., Neri I., and Tarabusi M. Eleutherococcus senticosus reduces cardiovascular stress response in healthy subjects: a randomized, placebo-controlled trial. Stress Health 18 (2002) 11-17
    • (2002) Stress Health , vol.18 , pp. 11-17
    • Facchinetti, F.1    Neri, I.2    Tarabusi, M.3
  • 7
    • 77950865882 scopus 로고    scopus 로고
    • International Conference on Harmonisation, 2000. ICH Harmonised Tripartite Guideline. Guideline for Good Clinical Practice E6(R1). Current Step 4 version dated 10 June 1996. Available at 〈http://www.ich.org/LOB/media/MEDIA482.pdf〉.
    • International Conference on Harmonisation, 2000. ICH Harmonised Tripartite Guideline. Guideline for Good Clinical Practice E6(R1). Current Step 4 version dated 10 June 1996. Available at 〈http://www.ich.org/LOB/media/MEDIA482.pdf〉.
  • 8
    • 77950860019 scopus 로고    scopus 로고
    • International Conference on Harmonization (ICH). Topic Q2 (R1), Validation of Analytical Procedures: Text and Methodology, Step 5, Note for Guidance for Validation of Analytical Procedure> Text and Methodologies. CPMP/ICH/381/95, June 1995. Available at 〈http://www.emea.europa.eu/pdfs/human/ich/038195en.pdf〉.
    • International Conference on Harmonization (ICH). Topic Q2 (R1), Validation of Analytical Procedures: Text and Methodology, Step 5, Note for Guidance for Validation of Analytical Procedure> Text and Methodologies. CPMP/ICH/381/95, June 1995. Available at 〈http://www.emea.europa.eu/pdfs/human/ich/038195en.pdf〉.
  • 9
    • 77950858730 scopus 로고    scopus 로고
    • International Organisation for Standardisation. EN ISO/IEC 17 025:2001 Standard Accreditation Requirements for QC Laboratories Operating under the GxP Compliance Requirements 2001. Available at 〈http://www.effichem.com〉.
    • International Organisation for Standardisation. EN ISO/IEC 17 025:2001 Standard Accreditation Requirements for QC Laboratories Operating under the GxP Compliance Requirements 2001. Available at 〈http://www.effichem.com〉.
  • 10
    • 27144465987 scopus 로고    scopus 로고
    • Impact of ChisanR (ADAPT 232) on the Quality - of - life and its Efficacy as an Adjuvant in the treatment of Acute Non-specific Pneumonia
    • Narimanian M., Badalyan M., Panosyan V., Gabrielyan E., Panossian A., Wikman G., and Wagner H. Impact of ChisanR (ADAPT 232) on the Quality - of - life and its Efficacy as an Adjuvant in the treatment of Acute Non-specific Pneumonia. Phytomedicine 12 (2005) 723-729
    • (2005) Phytomedicine , vol.12 , pp. 723-729
    • Narimanian, M.1    Badalyan, M.2    Panosyan, V.3    Gabrielyan, E.4    Panossian, A.5    Wikman, G.6    Wagner, H.7
  • 11
    • 63149169639 scopus 로고    scopus 로고
    • A randomized double-blind placebo controlled parallel group study of SHR-5 extract of Rhodiola rosea roots as treatment for patients with stress related fatigue
    • Olsson E.M.G., von Schéele B., Panossian A.G., 2009. A randomized double-blind placebo controlled parallel group study of SHR-5 extract of Rhodiola rosea roots as treatment for patients with stress related fatigue. Planta Med. 75, 105-112.
    • (2009) Planta Med , vol.75 , pp. 105-112
    • Olsson, E.M.G.1    von Schéele, B.2    Panossian, A.G.3
  • 12
    • 37449003708 scopus 로고    scopus 로고
    • The adaptogens Rhodiola and Schizandra modify the response to immobilization stress in rabbits by suppressing the increase of phosphorylated stress-activated protein kinase, nitric oxide and cortisol
    • Available at 〈http://www.la-press.com/the-adaptogens-rhodiola-and-schizandra-modify-the-response-to-immobili-a260〉
    • Panossian A., Hambartsumyan M., Hovanissian A., Gabrielyan E., and Wikman G. The adaptogens Rhodiola and Schizandra modify the response to immobilization stress in rabbits by suppressing the increase of phosphorylated stress-activated protein kinase, nitric oxide and cortisol. Drug Target Insights 1 (2007) 39-54. http://www.la-press.com/the-adaptogens-rhodiola-and-schizandra-modify-the-response-to-immobili-a260 Available at 〈http://www.la-press.com/the-adaptogens-rhodiola-and-schizandra-modify-the-response-to-immobili-a260〉
    • (2007) Drug Target Insights , vol.1 , pp. 39-54
    • Panossian, A.1    Hambartsumyan, M.2    Hovanissian, A.3    Gabrielyan, E.4    Wikman, G.5
  • 13
    • 27944504357 scopus 로고    scopus 로고
    • Stimulating effects of adaptogens: an overview of clinical trials of adaptogens with particular reference on their efficacy at single dose administration
    • Panossian A., and Wagner H. Stimulating effects of adaptogens: an overview of clinical trials of adaptogens with particular reference on their efficacy at single dose administration. Phytother Res. 19 (2005) 819-838
    • (2005) Phytother Res. , vol.19 , pp. 819-838
    • Panossian, A.1    Wagner, H.2
  • 14
    • 70549108394 scopus 로고    scopus 로고
    • Adaptogens exert a stress protective effect by modulation of expression of molecular chaperons
    • Panossian A., Wikman G., Andreeva L., Boykova A., Nikiforova D., and Timonina N. Adaptogens exert a stress protective effect by modulation of expression of molecular chaperons. Planta Med. 74 (2008) 1018
    • (2008) Planta Med. , vol.74 , pp. 1018
    • Panossian, A.1    Wikman, G.2    Andreeva, L.3    Boykova, A.4    Nikiforova, D.5    Timonina, N.6
  • 15
    • 67349132352 scopus 로고    scopus 로고
    • Adaptogens exert a stress protective effect by modulation of expression of molecular chaperons
    • Panossian, A., Wikman, G., Kaur, P., Asea, A., 2009. Adaptogens exert a stress protective effect by modulation of expression of molecular chaperons. Phytomedicine, 16, 617-622.
    • (2009) Phytomedicine , vol.16 , pp. 617-622
    • Panossian, A.1    Wikman, G.2    Kaur, P.3    Asea, A.4
  • 16
    • 0033203104 scopus 로고    scopus 로고
    • Plant adaptogens III: Earlier and more recent aspects and concepts on their modes of action
    • Panossian A., Wikman G., and Wagner H. Plant adaptogens III: Earlier and more recent aspects and concepts on their modes of action. Phytomedicine 6 (1999) 287-300
    • (1999) Phytomedicine , vol.6 , pp. 287-300
    • Panossian, A.1    Wikman, G.2    Wagner, H.3
  • 17
    • 45449105337 scopus 로고    scopus 로고
    • Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine
    • Panossian A., and Wikman G. Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine. J. Ethnopharmacol. 118 (2008) 183-212
    • (2008) J. Ethnopharmacol. , vol.118 , pp. 183-212
    • Panossian, A.1    Wikman, G.2
  • 18
    • 70549106478 scopus 로고    scopus 로고
    • Evidence based efficacy of adaptogens in fatigue and molecular mechanisms related to their stress protective action
    • Panossian A., and Wikman G. Evidence based efficacy of adaptogens in fatigue and molecular mechanisms related to their stress protective action. Curr. Clin. Pharmacol. 4 (2009) 198-219
    • (2009) Curr. Clin. Pharmacol. , vol.4 , pp. 198-219
    • Panossian, A.1    Wikman, G.2
  • 19
    • 85016625153 scopus 로고    scopus 로고
    • Adaptogens: tonic herbs for fatigue and stress
    • Panossian A.G. Adaptogens: tonic herbs for fatigue and stress. Altern. Complement. Ther. 9 (2004) 327-332
    • (2004) Altern. Complement. Ther. , vol.9 , pp. 327-332
    • Panossian, A.G.1
  • 20
    • 77950859531 scopus 로고    scopus 로고
    • Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress-protective activity
    • http://www.mdpi.com/1424-8247/3/1/188/pdf
    • Panossian A., and Wikman G. Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress-protective activity. Pharmaceuticals 3 (2010) 188-224. http://www.mdpi.com/1424-8247/3/1/188/pdf http://www.mdpi.com/1424-8247/3/1/188/pdf
    • (2010) Pharmaceuticals , vol.3 , pp. 188-224
    • Panossian, A.1    Wikman, G.2
  • 21
    • 77950860943 scopus 로고    scopus 로고
    • Ethical principles for medical research involving human subjects 2000. 18th WMA General Assembly
    • World Medical Association Declaration of Helsinki, Edinburgh Scotland, October
    • World Medical Association Declaration of Helsinki. Ethical principles for medical research involving human subjects 2000. 18th WMA General Assembly, Helsinki (Finland) June 1964 and 52nd WMA General Assembly, Edinburgh (Scotland), October 2000.
    • (2000) Helsinki (Finland) June 1964 and 52nd WMA General Assembly


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.