Pathologic correlates of dementia in individuals with lewy body disease

Brain Pathology

Volumn 20, Issue 3, 2010, Pages 654-659

  Sonnen, Joshua A ^a   Postupna, Nadia ^a   Larson, Eric B ^b   Crane, Paul K ^a,b   Rose, Shannon E ^a   Montine, Kathleen S ^a   Leverenz, James B ^a,c   Montine, Thomas J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b CENTER FOR HEALTH STUDIES   (United States)

^c DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

Epidemiology; Lewy body disease; Neuropathology

Indexed keywords

ALZHEIMER DISEASE; AUTOPSY; BRAIN INJURY; CAUDATE NUCLEUS; CHOLINERGIC SYSTEM; COGNITIVE DEFECT; COMORBIDITY; CONFERENCE PAPER; CORPUS STRIATUM; DEMENTIA; DIAGNOSTIC VALUE; DIFFUSE LEWY BODY DISEASE; DOPAMINERGIC SYSTEM; FRONTAL LOBE; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; NERVE PROJECTION; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NONHUMAN; NORADRENERGIC SYSTEM; OLIVARY NUCLEUS; PARKINSON DISEASE; SEROTONINERGIC SYSTEM;

COGNITION DISORDERS; HUMANS; LEWY BODY DISEASE;

EID: 77950803528     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2009.00371.x     Document Type: Conference Paper

References (44)

1. Aarsland D, Perry R, Brown A, Larsen JP, Ballard C (2005) Neuropathology of dementia in Parkinson's disease: a prospective, community-based study. Ann Neurol 58 : 773 776.
2. Apaydin H, Ahlskog JE, Parisi JE, Boeve BF, Dickson DW (2002) Parkinson disease neuropathology: later-developing dementia and loss of the levodopa response. Arch Neurol 59 : 102 112.
3. Bancher C, Braak H, Fischer P, Jellinger KA (1993) Neuropathological staging of Alzheimer lesions and intellectual status in Alzheimers and Parkinsons-disease patients. Neurosci Lett 162 : 179 182.
4. Dickson DW, Braak H, Duda JE, Duyckaerts C, Gasser T, Halliday GM et al (2009) Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria. Lancet Neurol 8 : 1150 1157.
5. Dorsey ER, Constantinescu R, Thompson JP, Biglan KM, Holloway RG, Kieburtz K et al (2007) Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030. Neurology 68 : 384 386.
6. Dubois B, Pillon B (1997) Cognitive deficits in Parkinson's disease. J Neurol 244 : 2 8.
7. Emre M (2003) Dementia associated with Parkinson's disease. Lancet Neurol 2 : 229 237.
8. Emre M, Aarsland D, Brown R, Burn DJ, Duyckaerts C, Mizuno Y et al (2007) Clinical diagnostic criteria for dementia associated with Parkinson's disease. Mov Disord 22 : 1689 1707 quiz 1837. (Pubitemid 47597592)
9. Frigerio R, Fujishiro H, Maraganore DM, Klos KJ, DelleDonne A, Heckman MG et al (2009) Comparison of risk factor profiles in incidental Lewy body disease and Parkinson disease. Arch Neurol 66 : 1114 1119.
10. Galvin JE, Pollack J, Morris JC (2006) Clinical phenotype of Parkinson disease dementia. Neurology 67 : 1605 1611.
11. Gaspar P, Gray F (1984) Dementia in idiopathic Parkinson's disease. A neuropathological study of 32 cases. Acta Neuropathol (Berl) 64 : 43 52.
12. Halliday GM, Li YW, Blumbergs PC, Joh TH, Cotton RG, Howe PR et al (1990) Neuropathology of immunohistochemically identified brainstem neurons in Parkinson's disease. Ann Neurol 27 : 373 385.
13. Haroutunian V, Serby M, Purohit DP, Perl DP, Marin D, Lantz M et al (2000) Contribution of lewy body inclusions to dementia in patients with and without Alzheimer disease neuropathological conditions. Arch Neurol 57 : 1145 1150.
14. Hughes AJ, Daniel SE, Blankson S, Lees AJ (1993) A clinicopathologic study of 100 cases of Parkinson's disease. Arch Neurol 50 : 140 148.
15. Hurtig HI, Trojanowski JQ, Galvin J, Ewbank D, Schmidt ML, Lee VMY et al (2000) Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson's disease. Neurology 54 : 1916 1921.
16. Jendroska K (1997) The relationship of Alzheimer-type pathology to dementia in Parkinson's disease. J Neural Transm Suppl 49 : 23 31. (Pubitemid 27351470)
17. Kalaitzakis ME, Pearce RK (2009) The morbid anatomy of dementia in Parkinson's disease. Acta Neuropathol 118 : 587 598.
18. Kish SJ, Shannak K, Hornykiewicz O (1988) Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. N Engl J Med 318 : 876 880.
19. Koerts J, Leenders KL, Koning M, Portman AT, van Beilen M (2007) Striatal dopaminergic activity (FDOPA-PET) associated with cognitive items of a depression scale (MADRS) in Parkinson's disease. Eur J Neurosci 25 : 3132 3136.
20. Larson EB, Shadlen MF, Wang L, McCormick WC, Bowen JD, Teri L, Kukull WA (2004) Survival after initial diagnosis of Alzheimer disease. Ann Intern Med 140 : 501 509.
21. Leroi I, Brandt J, Reich SG, Lyketsos CG, Grill S, Thompson R, Marsh L (2004) Randomized placebo-controlled trial of donepezil in cognitive impairment in Parkinson's disease. Int J Geriatr Psychiatry 19 : 1 8.
22. Leverenz JB, Hamilton R, Tsuang DW, Schantz A, Vavrek D, Larson EB et al (2008) Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient. Brain Pathol 18 : 220 224.
23. Levy G, Tang MX, Cote LJ, Louis ED, Alfaro B, Mejia H et al (2000) Motor impairment in PD: relationship to incident dementia and age. Neurology 55 : 539 544.
24. Markesbery WR, Jicha GA, Liu H, Schmitt FA (2009) Lewy body pathology in normal elderly subjects. J Neuropathol Exp Neurol 68 : 816 822.
25. Mattay VS, Tessitore A, Callicott JH, Bertolino A, Goldberg TE, Chase TN et al (2002) Dopaminergic modulation of cortical function in patients with Parkinson's disease. Ann Neurol 51 : 156 164.
26. Molano J, Boeve B, Ferman T, Smith G, Parisi J, Dickson D et al (2009) Mild cognitive impairment associated with limbic and neocortical lewy body disease: a clinicopathological study. Brain [Epub ahead of print] DOI: 10.1093/brain/awp280.
27. Monchi O, Petrides M, Mejia-Constain B, Strafella AP (2007) Cortical activity in Parkinson's disease during executive processing depends on striatal involvement. Brain 130 : 233 244.
28. Nelson PT, Kryscio RJ, Jicha GA, Abner EL, Schmitt FA, Xu LO et al (2009) Relative preservation of MMSE scores in autopsy-proven dementia with Lewy bodies. Neurology 73 : 1127 1133.
29. Nussbaum RL, Ellis CE (2003) Alzheimer's disease and Parkinson's disease. N Engl J Med 348 : 1356 1364.
30. Papapetropoulos S, Lieberman A, Gonzalez J, Mash DC (2005) Can Alzheimer's type pathology influence the clinical phenotype of Parkinson's disease? Acta Neurol Scand 111 : 353 359.
31. Parkinson J (1817) An Essay on the Shaking Palsy. Sherwood, Neely and Jones
32. Rinne JO, Portin R, Ruottinen H, Nurmi E, Bergman J, Haaparanta M, Solin O (2000) Cognitive impairment and the brain dopaminergic system in Parkinson disease: [18F]fluorodopa positron emission tomographic study. Arch Neurol 57 : 470 475.
33. Rinne JO, Rummukainen J, Paljarvi L, Sako E, Molsa P, Rinne UK (1989) Neuronal loss in the substantia nigra in patients with Alzheimer's disease and Parkinson's disease in relation to extrapyramidal symptoms and dementia. Prog Clin Biol Res 317 : 325 332.
34. Rogers J, Bloom FE (1985) Neurotransmitter metabolism and function in the aging central nervous system. In : Handbook of the Biology of Aging. 6th (ed.), pp. 645 691. Van Nostrand Reinhold
35. Rub U, Del Tredici K, Schultz C, Ghebremedhin E, de Vos RAI, Steur EJ, Braak H (2002) Parkinson's disease: the thalamic components of the limbic loop are severely impaired by a-synuclein immunopositive inclusion body pathology. Neurobiol Aging 23 : 245 254.
36. Sawamoto N, Honda M, Hanakawa T, Aso T, Inoue M, Toyoda H et al (2007) Cognitive slowing in Parkinson disease is accompanied by hypofunctioning of the striatum. Neurology 68 : 1062 1068.
37. Scatton B, Javoy-Agid F, Rouquier L, Dubois B, Agid Y (1983) Reduction of cortical dopamine, noradrenaline, serotonin and their metabolites in Parkinson's disease. Brain Res 275 : 321 328.
38. Sonnen JA, Larson EB, Crane PK, Haneuse S, Li G, Schellenberg GD et al (2007) Pathological correlates of dementia in a longitudinal, population-based sample of aging. Ann Neurol 62 : 406 413.
39. Teng EL, Hasegawa K, Homma A, Imai Y, Larson E, Graves A et al (1994) The Cognitive Abilities Screening Instrument (CASI): a practical test for cross-cultural epidemiological studies of dementia. Int Psychogeriatr 6 : 45 58 discussion 62.
40. Thomas AJ, Burn DJ, Rowan EN, Littlewood E, Newby J, Cousins D et al (2005) A comparison of the efficacy of donepezil in Parkinson's disease with dementia and dementia with Lewy bodies. Int J Geriatr Psychiatry 20 : 938 944.
41. Torack RM, Morris JC (1988) The association of ventral tegmental area histopathology with adult dementia. Arch Neurol 45 : 497 501.
42. Williams SM, Goldman-Rakic PS (1998) Widespread origin of the primate mesofrontal dopamine system. Cereb Cortex 8 : 321 345.
43. Zaja-Milatovic S, Keene CD, Montine KS, Leverenz JB, Tsuang D, Montine TJ (2006) Selective dendritic degeneration of medium spiny neurons in dementia with Lewy bodies. Neurology 66 : 1591 1593.
44. Zaja-Milatovic S, Milatovic D, Schantz AM, Zhang J, Montine KS, Samii A et al (2005) Dendritic degeneration in neostriatal medium spiny neurons in Parkinson disease. Neurology 64 : 545 547.