Cognitive slowing in Parkinson disease is accompanied by hypofunctioning of the striatum

Neurology

Volumn 68, Issue 13, 2007, Pages 1062-1068

  Sawamoto, N ^a   Honda, M ^a,c,d   Hanakawa, T ^a,c   Aso, T ^a   Inoue, M ^a   Toyoda, H ^e   Ishizu, K ^a   Fukuyama, H ^a   Shibasaki, H ^a,b,f  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^f TAKEDA GENERAL HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM; OXYGEN 15;

ADULT; ARTICLE; BASAL GANGLION; BRAIN DYSFUNCTION; BRAIN FUNCTION; BRAIN NERVE CELL; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; CORPUS STRIATUM; FEMALE; FRONTAL LOBE; HUMAN; HUMAN CELL; MALE; MENTAL DETERIORATION; MENTAL PERFORMANCE; MOTOR DYSFUNCTION; PARKINSON DISEASE; POSITRON EMISSION TOMOGRAPHY; PREMOTOR CORTEX; PRIORITY JOURNAL; TASK PERFORMANCE; VELOCITY; VERBAL MEMORY;

BRAIN MAPPING; CEREBROVASCULAR CIRCULATION; COGNITION DISORDERS; CORPUS STRIATUM; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTOR CORTEX; NEURAL PATHWAYS; NEUROPSYCHOLOGICAL TESTS; PARKINSON DISEASE; POSITRON-EMISSION TOMOGRAPHY; PREDICTIVE VALUE OF TESTS; REACTION TIME; REFERENCE VALUES;

EID: 34147101251     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000257821.28992.db     Document Type: Article

References (37)

1. Owen AM, Doyon J, Dagher A, Sadikot A, Evans AC. Abnormal basal ganglia outflow in Parkinson's disease identified with PET. Implications for higher cortical functions. Brain 1998;121:949-965.
2. Dagher A, Owen AM, Boecker H, Brooks DJ. The role of the striatum and hippocampus in planning: a PET activation study in Parkinson's disease. Brain 2001;124:1020-1032.
3. Lewis SJ, Dove A, Robbins TW, Barker RA, Owen AM. Cognitive impairments in early Parkinson's disease are accompanied by reductions in activity in frontostriatal neural circuitry. J Neurosci 2003;23:6351-6356.
4. Mattay VS, Tessitore A, Callicott JH, et al. Dopaminergic modulation of cortical function in patients with Parkinson's disease. Ann Neurol 2002;51:156-164.
5. Monchi O, Petrides M, Doyon J, Postuma RB, Worsley K, Dagher A. Neural bases of set-shifting deficits in Parkinson's disease. J Neurosci 2004;24:702-710.
6. Sawamoto N, Honda M, Hanakawa T, Fukuyama H, Shibasaki H. Cognitive slowing in Parkinson's disease: a behavioral evaluation independent of motor slowing. J Neurosci 2002;22:5198-5203.
7. Vingerhoets FJ, Schulzer M, Calne DB, Snow BJ. Which clinical sign of Parkinson's disease best reflects the nigrostriatal lesion? Ann Neurol 1997;41:58-64.
8. Berardelli A, Rothwell JC, Thompson PD, Hallett M. Pathophysiology of bradykinesia in Parkinson's disease. Brain 2001;124:2131-2146.
9. Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 1986;9:357-381.
10. Pate DS, Margolin DI. Cognitive slowing in Parkinson's and Alzheimer's patients: distinguishing bradyphrenia from dementia. Neurology 1994;44:669-674.
11. Carlin D, Bonerba J, Phipps M, Alexander G, Shapiro M, Grafman J. Planning impairments in frontal lobe dementia and frontal lobe lesion patients. Neuropsychologia 2000;38:655-665.
12. Hanakawa T, Honda M, Sawamoto N, et al. The role of rostral Brodmann area 6 in mental-operation tasks: an integrative neuroimaging approach. Cereb Cortex 2002;12:1157-1170.
13. Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992;55:181-184.
14. Talairach J, Tournoux P. Co-planar stereotaxic atlas of the human brain. New York: Thieme Medical, 1988.
15. Evans AC, Collins DL, Mills SR, Brown ED, Kelly RL. 3D statistical neuroanatomical models from 305 MRI volumes. In: Proc IEEE-Nucl Sci Symp Med Imaging, 1993:1813-1817.
16. Timmer J, Lauk M, Deuschl G. Quantitative analysis of tremor time series. Electroencephalogr Clin Neurophysiol 1996;101:461-468.
17. Deuschl G, Krack P, Lauk M, Timmer J. Clinical neurophysiology of tremor. J Clin Neurophysiol 1996;13:110-121.
18. Picard N, Strick PL. Motor areas of the medial wall: a review of their location and functional activation. Cereb Cortex 1996;6:342-353.
19. Kish SJ, Shannak K, Hornykiewicz O. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. N Engl J Med 1988;318:876-880.
20. Bischoff-Grethe A, Martin M, Mao H, Berns GS. The context of uncertainty modulates the subcortical response to predictability. J Cogn Neurosci 2001;13:986-993.
21. Poldrack RA, Sabb FW, Foerde K, et al. The neural correlates of motor skill automaticity. J Neurosci 2005;25:5356-64.
22. Marsden CD. The mysterious motor function of the basal ganglia: the Robert Wartenberg Lecture. Neurology 1982;32:514-539.
23. Selemon LD, Goldman-Rakic PS. Longitudinal topography and interdigitation of corticostriatal projections in the rhesus monkey. J Neurosci 1985;5:776-794.
24. Schultz W, Apicella P, Romo R, Scarnati E. Context-dependent activity in primate striatum reflecting past and future behavioral events. In: Houk JC, Davis JL, Beiser DG, eds. Models of information processing in the basal ganglia. Cambridge MA: MIT Press, 1995:11-27.
25. Braver TS, Cohen JD, Nystrom LE, Jonides J, Smith EE, Noll DC. A parametric study of prefrontal cortex involvement in human working memory. Neuroimage 1997;5:49-62.
26. Rypma B, Prabhakaran V, Desmond JE, Glover GH, Gabrieli JD. Load-dependent roles of frontal brain regions in the maintenance of working memory. Neuroimage 1999;9:216-226.
27. Fry AF, Hale S. Relationships among processing speed, working memory, and fluid intelligence in children. Biol Psychol 2000;54:1-34.
28. Turner RS, Grafton ST, Votaw JR, Delong MR, Hoffman JM. Motor subcircuits mediating the control of movement velocity: a PET study. J Neurophysiol 1998;80:2162-2176.
29. Taniwaki T, Okayama A, Yoshiura T, et al. Reappraisal of the motor role of basal ganglia: a functional magnetic resonance image study. J Neurosci 2003;23:3432-3438.
30. Inase M, Tokuno H, Nambu A, Akazawa T, Takada M. Corticostriatal and corticosubthalamic input zones from the presupplementary motor area in the macaque monkey: comparison with the input zones from the supplementary motor area [erratum appears in Brain Res 2000;861:190]. Brain Res 1999;833:191-201.
31. Tanaka S, Honda M, Sadato N. Modality-specific cognitive function of medial and lateral human Brodmann area 6. J Neurosci 2005;25:496-501.
32. Mendez MF, Adams NL, Lewandowski KS. Neurobehavioral changes associated with caudate lesions. Neurology 1989;39:349-354.
33. Cromwell HC, Berridge KC. Implementation of action sequences by a neostriatal site: a lesion mapping study of grooming syntax. J Neurosci 1996;16:3444-3458.
34. Schultz W, Romo R. Role of primate basal ganglia and frontal cortex in the internal generation of movements. I. Preparatory activity in the anterior striatum. Exp Brain Res 1992;91:363-384.
35. Playford ED, Jenkins IH, Passingham RE, Nutt J, Frackowiak RS, Brooks DJ. Impaired mesial frontal and putamen activation in Parkinson's disease: a positron emission tomography study. Ann Neurol 1992;32:151-161.
36. Catalan MJ, Ishii K, Honda M, Samii A, Hallett M. A PET study of sequential finger movements of varying length in patients with Parkinson's disease. Brain 1999;122:483-495.
37. Jenkins IH, Fernandez W, Playford ED, et al. Impaired activation of the supplementary motor area in Parkinson's disease is reversed when akinesia is treated with apomorphine. Ann Neurol 1992;32:749-757.