Anti-tumor activity of Sann-Joong-Kuey-Jian-Tang alone and in combination with 5-fluorouracil in a human colon cancer colo 205 cell xenograft model

Molecular Medicine Reports

Volumn 3, Issue 2, 2010, Pages 227-231

  Cheng, Chun Yuan ^a,b   Lin, Yi Hsiang ^c   Su, Chin Cheng ^c  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c TZU CHI UNIVERSITY   (Taiwan)

Author keywords

5 fluorouracil; Colo 205 cell xenograft model; Microtubule associated protein light chain 3; Sann Joong Kuey Jian Tang

Indexed keywords

ANTINEOPLASTIC AGENT; FLUOROURACIL; MICROTUBULE ASSOCIATED PROTEIN; SANN JOONG KUEY JIAN TANG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BODY WEIGHT; CANCER CELL; CANCER INHIBITION; CANCER SIZE; CANCER SURGERY; CARBON DIOXIDE BREATHING; COLON CANCER; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG DOSE REGIMEN; DRUG MEGADOSE; HUMAN; HUMAN CELL; IN VIVO STUDY; LIGHT CHAIN; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REDUCTION; SCID MOUSE; WESTERN BLOTTING; XENOGRAFT;

ANIMALIA; CITRUS MACROPHYLLA; MUS;

EID: 77950792041     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr_000000244     Document Type: Article

References (16)

1. Rauh R, Kahl S, Boechzelt H, Bauer R, Kaina B and Efferth T: Molecular biology of cantharidin in cancer cells. Chin Med 2: 8, 2007.
2. Jemal A, Tiwari RC , Murray T, et al: Cancer statistics, 2004. CA Cancer J Clin 54: 8-29, 2004.
3. Statistics of Causes of Death, 2007. Department of Health, Executive Yuan, Taipei, Taiwan R.O.C, p33, 2008.
4. Cheng CY, Lin YH and Su CC: Sann-Joong-Kuey-Jian-Tang increases the protein expression of microtubule-associated protein II light chain 3 in human colon cancer colo 205 cells. Mol Med Rep 2: 707-711, 2009.
5. James K, Eisenhauer E, Christian M, Terenziani M, Vena D and Mudal A: Measuring response in solid tumors: unidimensional versus bidimensinal measurement. J Natl Cancer Inst 91: 523-528, 1999.
6. Hsu YL, Yen MH, Kuo PL, et al: San-Zhong-Kui-Jian-Tang, a traditional Chinese medicine prescription, inhibits the proliferation of human breast cancer cells by blocking cell cycle progression and inducing apoptosis. Biol Pharm Bull 29: 2388-2394, 2006.
7. Su CC and Lin YH: Tanshinone IIA inhibits human breast cancer cells through increased Bax to Bcl-xL ratios. Int J Mol Med 22: 357-361, 2008.
8. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
9. Chen HC, Hsieh WT, Chang WC and Chung JG: Aloe-emodin induced in vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells. Food Chem Toxicol 42: 1251-1257, 2004.
10. E Efferth T, Kahl S, Paulus K, et al: Phytochemistry and pharmacogenomics of natural products derived from traditional Chinese medicine and Chinese materia medica with activity against tumor cells. Mol Cancer Ther 7: 152-161, 2008.
11. Parekh HS, Liu G and Wei MQ: A new dawn for the use of traditional Chinese medicine in cancer therapy. Mol Cancer 8: 1-8, 2009.
12. 12.Clarke PG: Developmental cell death: morphological diversity and multiple mechanisms. Anat Embryol 181: 195-213, 1990.
13. Moretti Lu, Yang ES, Kim KW and Lu B: Autophagy signaling in cancer and its potential as novel target to improve anticancer therapy. Drug Resist Updat 10: 135-143, 2007.
14. Kirkegaard K, Taylor MP and Jackson WT: Cellular autophagy: surrender, avoidance and subversion by microorganisms. Nat Rev Microbiol 2: 301-314, 2004.
15. E Eskelinen EL , Prescott AR , Cooper J, et al: Inhibition of autophagy in mitotic animal cells. Traffic 3: 878-893, 2002.
16. Cheng CY, Lin YH and Su CC: Sann-Joong-Kuey-Jian-Tang up-regulates the protein expression of Fas and TNF-α in colo 205 cells in vivo and in vitro. Mol Med Rep 3: 63-67, 2010.