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Volumn 15, Issue 2, 2010, Pages 203-211

Positive and negative drug selection pressures on the N348I connection domain mutation: New insights from in vivo data

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; EFAVIRENZ; N348I PROTEIN; NEVIRAPINE; PROTEIN; STAVUDINE; TENOFOVIR DISOPROXIL; UNCLASSIFIED DRUG; ZIDOVUDINE;

EID: 77950652922     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: 10.3851/IMP1511     Document Type: Article
Times cited : (10)

References (29)
  • 1
    • 37849041431 scopus 로고    scopus 로고
    • Expanded range of HIV-1 reverse transcriptase mutations detected through long range sequencing
    • 8-11 February San Francisco, CA, USA. Abstract 629
    • Kagan R, Winters M, Merigan T, Heseltine P. Expanded range of HIV-1 reverse transcriptase mutations detected through long range sequencing. 11th Conference on Retroviruses and Opportunistic Infections. 8-11 February 2004, San Francisco, CA, USA. Abstract 629.
    • (2004) 11th Conference on Retroviruses and Opportunistic Infections
    • Kagan, R.1    Winters, M.2    Merigan, T.3    Heseltine, P.4
  • 2
    • 33847018853 scopus 로고    scopus 로고
    • UK collaborative group on HIV Drug Resistance. Identification of accessory mutations associated with high-level resistance in HIV-1 reverse transcriptase
    • Cane PA, Green H, Fearnhill E, Dunn D, UK collaborative group on HIV Drug Resistance. Identification of accessory mutations associated with high-level resistance in HIV-1 reverse transcriptase. AIDS 2007; 21:447-455.
    • (2007) AIDS , vol.21 , pp. 447-455
    • Cane, P.A.1    Green, H.2    Fearnhill, E.3    Dunn, D.4
  • 3
    • 52049107430 scopus 로고    scopus 로고
    • Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3′-azido-3′-deoxythymidine through both RNase H-dependent and -independent mechanisms
    • Ehteshami M, Beilhartz GL, Scarth BJ, et al. Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3′-azido-3′-deoxythymidine through both RNase H-dependent and -independent mechanisms. J Biol Chem 2008; 283:22222-22232.
    • (2008) J Biol Chem , vol.283 , pp. 22222-22232
    • Ehteshami, M.1    Beilhartz, G.L.2    Scarth, B.J.3
  • 5
    • 49449103962 scopus 로고    scopus 로고
    • HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision
    • Delviks-Frankenberry KA, Nikolenko GN, Boyer PL, et al. HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision. Proc Natl Acad Sci USA 2008; 105:10943-10948.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10943-10948
    • Delviks-Frankenberry, K.A.1    Nikolenko, G.N.2    Boyer, P.L.3
  • 6
    • 38049028352 scopus 로고    scopus 로고
    • N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance
    • Yap SH, Sheen CW, Fahey J, et al. N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance. PLoS Med 2007; 4:e335.
    • (2007) PLoS Med , vol.4
    • Yap, S.H.1    Sheen, C.W.2    Fahey, J.3
  • 7
    • 41149145592 scopus 로고    scopus 로고
    • Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors
    • DOI 10.1128/JVI.01154-07
    • Hachiya A, Kodama EN, Sarafianos SG, et al. Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors. J Virol 2008; 82:3261-3270. (Pubitemid 351429905)
    • (2008) Journal of Virology , vol.82 , Issue.7 , pp. 3261-3270
    • Hachiya, A.1    Kodama, E.N.2    Sarafianos, S.G.3    Schuckmann, M.M.4    Sakagami, Y.5    Matsuoka, M.6    Takiguchi, M.7    Gatanaga, H.8    Oka, S.9
  • 8
    • 34147172072 scopus 로고    scopus 로고
    • Infrequent occurrence of mutations in the C-terminal regions of reverse transcriptase modulates susceptibility to RT inhibitors
    • 13-17 June Sitges, Spain. Abstract S143
    • Gupta S, Fransen S, Paxinos EE, et al. Infrequent occurrence of mutations in the C-terminal regions of reverse transcriptase modulates susceptibility to RT inhibitors. XV International HIV Drug Resistance Workshop. 13-17 June 2006, Sitges, Spain. Abstract S143.
    • (2006) XV International HIV Drug Resistance Workshop
    • Gupta, S.1    Fransen, S.2    Paxinos, E.E.3
  • 11
    • 38049007454 scopus 로고    scopus 로고
    • Should we include connection domain mutations of HIV-1 reverse transcriptase in HIV resistance testing?
    • Gotte M. Should we include connection domain mutations of HIV-1 reverse transcriptase in HIV resistance testing? PLoS Med 2007; 4:e346.
    • (2007) PLoS Med , vol.4
    • Gotte, M.1
  • 12
    • 77950652661 scopus 로고    scopus 로고
    • N348I in the connection domain of HIV-1 reverse transcriptase exhibits differential effects on RNase H activity in response to NNRTI
    • 8-11 February Montréal, QC, Canada. Abstract 624
    • Biondi M, Beilhartz G, Götte M. N348I in the connection domain of HIV-1 reverse transcriptase exhibits differential effects on RNase H activity in response to NNRTI. 16th Conference on Retroviruses and Opportunistic Infections. 8-11 February 2009, Montréal, QC, Canada. Abstract 624.
    • (2009) 16th Conference on Retroviruses and Opportunistic Infections
    • Biondi, M.1    Beilhartz, G.2    Götte, M.3
  • 13
    • 31344445595 scopus 로고    scopus 로고
    • Time trends in primary resistance to HIV drugs in the United Kingdom: Multicentre observational study
    • UK Group on Transmitted HIV Drug Resistance
    • UK Group on Transmitted HIV Drug Resistance. Time trends in primary resistance to HIV drugs in the United Kingdom: multicentre observational study. BMJ 2005; 331:1368-1371.
    • (2005) BMJ , vol.331 , pp. 1368-1371
  • 14
    • 12144290367 scopus 로고    scopus 로고
    • The creation of a large UK-based multicentre cohort of HIV-infected individuals: The UK Collaborative HIV Cohort (UK CHIC) Study
    • UK Collaborative HIV Cohort Steering Committee
    • UK Collaborative HIV Cohort Steering Committee. The creation of a large UK-based multicentre cohort of HIV-infected individuals: the UK Collaborative HIV Cohort (UK CHIC) Study. HIV Med 2004; 5:115-124.
    • (2004) HIV Med , vol.5 , pp. 115-124
  • 15
    • 35748933494 scopus 로고    scopus 로고
    • Update of the drug resistance mutations in HIV-1: 2007
    • Johnson VA, Brun-Vézinet F, Clotet B, et al. Update of the drug resistance mutations in HIV-1: 2007. Top HIV Med 2007; 15:119-125.
    • (2007) Top HIV Med , vol.15 , pp. 119-125
    • Johnson, V.A.1    Brun-Vézinet, F.2    Clotet, B.3
  • 16
    • 73649114589 scopus 로고    scopus 로고
    • The impact of the 0-0 cell on measures of amino acid covariation
    • Dunn D, von Wyl V, Price H, Asboe D. The impact of the 0-0 cell on measures of amino acid covariation. AIDS 2010; 24:159-160.
    • (2010) AIDS , vol.24 , pp. 159-160
    • Dunn, D.1    Von Wyl, V.2    Price, H.3    Asboe, D.4
  • 17
    • 0037102914 scopus 로고    scopus 로고
    • Flexible parametric proportional-hazards and proportional-odds models for censored survival data, with application to prognostic modelling and estimation of treatment effects
    • DOI 10.1002/sim.1203
    • Royston P, Parmar MK. Flexible parametric proportional hazards and proportional odds models for censored survival data, with application to prognostic modelling and estimation of treatment effects. Stat Med 2002; 21:2175-2197. (Pubitemid 34830755)
    • (2002) Statistics in Medicine , vol.21 , Issue.15 , pp. 2175-2197
    • Royston, P.1    Parmar, M.K.B.2
  • 19
    • 0025031812 scopus 로고
    • No adjustments are needed for multiple comparisons
    • Rothman KJ. No adjustments are needed for multiple comparisons. Epidemiology 1990; 1:43-46.
    • (1990) Epidemiology , vol.1 , pp. 43-46
    • Rothman, K.J.1
  • 20
    • 73649093077 scopus 로고    scopus 로고
    • Prevalence and patterns of antiretroviral drug resistance at low plasma HIV RNA load levels
    • Geretti AM, Phillips AN, Kaye S, Booth C, Garcia A, Mackie N. Prevalence and patterns of antiretroviral drug resistance at low plasma HIV RNA load levels. Antivir Ther 2008; 13 Suppl 3:A156.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Geretti, A.M.1    Phillips, A.N.2    Kaye, S.3    Booth, C.4    Garcia, A.5    Mackie, N.6
  • 22
    • 77950664625 scopus 로고    scopus 로고
    • Prevalence and in vitro characteristics of reverse transcriptase N348I mutation in non-B subtypes, in the absence of viral load monitoring: The development of ART in Africa, nevirapine or abacavir substudy
    • 8-11 February Montréal, QC, Canada. Abstract 643
    • McCormick A, Burke A, Katundu P, et al. Prevalence and in vitro characteristics of reverse transcriptase N348I mutation in non-B subtypes, in the absence of viral load monitoring: the development of ART in Africa, nevirapine or abacavir substudy. 16th Conference on Retroviruses and Opportunistic Infections. 8-11 February 2009, Montréal, QC, Canada. Abstract 643.
    • (2009) 16th Conference on Retroviruses and Opportunistic Infections
    • McCormick, A.1    Burke, A.2    Katundu, P.3
  • 23
    • 33748052358 scopus 로고    scopus 로고
    • Antagonism between the HIV-1 reverse-transcriptase mutation K65R and thymidine-analogue mutations at the genomic level
    • DOI 10.1086/505711
    • Parikh UM, Barnas DC, Faruki H, Mellors JW. Antagonism between the HIV-1 reverse-transcriptase mutation K65R and thymidine-analogue mutations at the genomic level. J Infect Dis 2006; 194:651-660. (Pubitemid 44297851)
    • (2006) Journal of Infectious Diseases , vol.194 , Issue.5 , pp. 651-660
    • Parikh, U.M.1    Barnas, D.C.2    Faruki, H.3    Mellors, J.W.4
  • 24
    • 77950660193 scopus 로고    scopus 로고
    • Phenotypic role of HIV-1 reverse transcriptase C-terminal mutations and their relation with classical thymidine analogue mutations
    • 19-22 July Cape Town, South Africa. Abstract WEPEA079
    • Bohrer Lengruber R, Delviks-Frankenberry K, Nikolenko G, et al. Phenotypic role of HIV-1 reverse transcriptase C-terminal mutations and their relation with classical thymidine analogue mutations. 5th IAS Conference on HIV Pathogenesis, Treatment and Prevention. 19-22 July 2009, Cape Town, South Africa. Abstract WEPEA079.
    • (2009) 5th IAS Conference on HIV Pathogenesis, Treatment and Prevention
    • Bohrer Lengruber, R.1    Delviks-Frankenberry, K.2    Nikolenko, G.3
  • 29
    • 77950666559 scopus 로고    scopus 로고
    • Mutation A376S in the RT connection domain is associated with an increased risk of virological failure to nevirapine-based therapy in NNRTI-naive HIV-infected subjects: The EuroSIDA study
    • 8-11 February Montréal, QC, Canada. Abstract 646
    • Paredes R, Bannister W, Cozzi-Lepri A, et al. Mutation A376S in the RT connection domain is associated with an increased risk of virological failure to nevirapine-based therapy in NNRTI-naive HIV-infected subjects: the EuroSIDA study. 16th Conference on Retroviruses and Opportunistic Infections. 8-11 February 2009, Montréal, QC, Canada. Abstract 646.
    • (2009) 16th Conference on Retroviruses and Opportunistic Infections
    • Paredes, R.1    Bannister, W.2    Cozzi-Lepri, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.