GABAB receptor activation exacerbates spontaneous spike-and-wave discharges in DBA/2J mice

Seizure

Volumn 19, Issue 4, 2010, Pages 226-231

  Bortolato, Marco ^a,b   Frau, Roberto ^a,b   Orrù, Marco ^b   Fà, Mauro ^b   Dessì, Christian ^b   Puligheddu, Monica ^b   Barberini, Luigi ^b   Pillolla, Giuliano ^b   Polizzi, Lorenzo ^b   Santoni, Federico ^b   Mereu, Giampaolo ^b   Marrosu, Francesco ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Absence rodent models; Baclofen; DBA 2J mice; EEG pattern; GABAB receptors; GBL

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; 4 HYDROXYBUTYRIC ACID; 5,5 DIMETHYL 2 MORPHOLINEACETIC ACID; BACLOFEN; GAMMA BUTYROLACTONE; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT;

ABSENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DBA 2 MOUSE; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MEGADOSE; DRUG RECEPTOR BINDING; EPILEPTIC DISCHARGE; LOCOMOTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; SPIKE AND WAVE DISCHARGE; SPIKE WAVE; ANIMAL; DBA MOUSE; ELECTROENCEPHALOGRAPHY; METABOLISM; MOTOR ACTIVITY; PATHOPHYSIOLOGY;

ANIMALS; BACLOFEN; ELECTROENCEPHALOGRAPHY; EPILEPSY, ABSENCE; GABA AGONISTS; MALE; MICE; MICE, INBRED DBA; MOTOR ACTIVITY; RECEPTORS, GABA-B;

EID: 77950630250     PISSN: 10591311     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seizure.2010.02.007     Document Type: Article

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