IGF-1 increases macrophage motility via PKC/p38-dependent αvβ3-integrin inside-out signaling

Biochemical and Biophysical Research Communications

Volumn 394, Issue 3, 2010, Pages 786-791

  Furundzija, Vesna ^a   Fritzsche, Jan ^a   Kaufmann, Jan ^a   Meyborg, Heike ^a   Fleck, Eckart ^a   Kappert, Kai ^b,c   Stawowy, Philipp ^a  

^a DEUTSCHES HERZZENTRUM BERLIN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

IGF 1; Inside out signaling; Integrin; Macrophages; Migration

Indexed keywords

ACTIN; ADAPTOR PROTEIN; ARGINYLGLYCYLASPARTIC ACID; FOCAL ADHESION KINASE; FURIN; GELATINASE A; GELATINASE B; ILOMASTAT; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCLONAL ANTIBODY LM 609; PAXILLIN; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; VIMENTIN; VITRONECTIN RECEPTOR;

ARTICLE; ATHEROMA; ATHEROSCLEROSIS; CELL MIGRATION; CELL MOTILITY; CHEMOTAXIS; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVATION; FOCAL ADHESION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INFLAMMATION; MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

ATHEROSCLEROSIS; CELL LINE; CELL MOVEMENT; CHEMOTAXIS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTEGRIN ALPHAVBETA3; MACROPHAGES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE C; SIGNAL TRANSDUCTION;

EID: 77950629143     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.03.072     Document Type: Article

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