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Volumn 28, Issue 3, 2006, Pages 723-730

Insulin-like growth factor-I promotes migration in human androgen-independent prostate cancer cells via the αvβ3 integrin and PI3-K/Akt signaling

Author keywords

Cell motility; IGF I; Integrins; PI3 K Akt; Prostate cancer

Indexed keywords

1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ACTIN; ANDROGEN; ANTIBODY; CHROMONE DERIVATIVE; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MORPHOLINE DERIVATIVE; NITRILE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; VITRONECTIN RECEPTOR;

EID: 33645224456     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (41)

References (48)
  • 2
    • 9644279380 scopus 로고    scopus 로고
    • Androgen deprivation therapy for prostate cancer: Current status and future prospects
    • Miyamoto H, Messing EM and Chang C: Androgen deprivation therapy for prostate cancer: current status and future prospects. Prostate 61: 332-353, 2004.
    • (2004) Prostate , vol.61 , pp. 332-353
    • Miyamoto, H.1    Messing, E.M.2    Chang, C.3
  • 3
    • 16544369695 scopus 로고    scopus 로고
    • Emergence of metastatic hormone-refractory disease in prostate cancer after anti-androgen therapy
    • Lee ECY and Tenniswood MPR: Emergence of metastatic hormone-refractory disease in prostate cancer after anti-androgen therapy. J Cell Biochem 91: 662-670, 2004.
    • (2004) J Cell Biochem , vol.91 , pp. 662-670
    • Lee, E.C.Y.1    Tenniswood, M.P.R.2
  • 4
    • 0036219874 scopus 로고    scopus 로고
    • Mechanisms involved in the progression of androgen-independent prostate cancers: It is only the cancer cell's fault
    • Arnold JT and Isaacs JT: Mechanisms involved in the progression of androgen-independent prostate cancers: it is only the cancer cell's fault. Endocr-Rel Cancer 9: 61-73, 2002.
    • (2002) Endocr-Rel Cancer , vol.9 , pp. 61-73
    • Arnold, J.T.1    Isaacs, J.T.2
  • 6
    • 0038481707 scopus 로고    scopus 로고
    • Current strategies in the management of hormone refractory prostate cancer
    • Martel CL, Gumerlock PH, Meyers FJ and Lara PN: Current strategies in the management of hormone refractory prostate cancer. Cancer Treat Rev 29: 171-187, 2003.
    • (2003) Cancer Treat Rev , vol.29 , pp. 171-187
    • Martel, C.L.1    Gumerlock, P.H.2    Meyers, F.J.3    Lara, P.N.4
  • 7
    • 2342550633 scopus 로고    scopus 로고
    • Novel therapeutic strategies for androgen-independent prostate cancer: An update
    • Assikis VJ and Simons JW: Novel therapeutic strategies for androgen-independent prostate cancer: an update. Semin Oncol 31: 26-32, 2004.
    • (2004) Semin Oncol , vol.31 , pp. 26-32
    • Assikis, V.J.1    Simons, J.W.2
  • 10
    • 0027152122 scopus 로고
    • Insulin-Like growth factor I: Action and receptor characterization in human prostate cancer cell lines
    • Iwamura M, Sluss PM, Casamento JB and Cockett ATK: Insulin-like growth factor I: action and receptor characterization in human prostate cancer cell lines. Prostate 22: 243-252, 1993. (Pubitemid 23184735)
    • (1993) Prostate , vol.22 , Issue.3 , pp. 243-252
    • Iwamura, M.1    Sluss, P.M.2    Casamento, J.B.3    Cockett, A.T.K.4
  • 11
    • 0028326130 scopus 로고
    • Regulation of DU145 human prostate cancer cell proliferation by insulin-like growth factors and its interaction with the epidermal growth factor autocrine loop
    • Connolly JM and Rose DP: Regulation of DU145 human prostate cancer cell proliferation by insulin-like growth factors and its interaction with the epidermal growth factor autocrine loop. Prostate 24: 167-175, 1994.
    • (1994) Prostate , vol.24 , pp. 167-175
    • Connolly, J.M.1    Rose, D.P.2
  • 13
    • 0032922082 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone agonists interfere with the mitogenic activity of the insulin-like growth factor system in androgen-independent prostate cancer cells
    • Montagnani Marelli M, Moretti RM, Dondi D, Motta M and Limonta P: Luteinizing hormone-releasing hormone agonists interfere with the mitogenic activity of the insulin-like growth factor system in androgen-independent prostate cancer cells. Endocrinology 140: 329-334, 1999.
    • (1999) Endocrinology , vol.140 , pp. 329-334
    • Montagnani Marelli, M.1    Moretti, R.M.2    Dondi, D.3    Motta, M.4    Limonta, P.5
  • 14
    • 0029937307 scopus 로고    scopus 로고
    • Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo
    • Burfeind P, Chernicky CL, Rininsland F and Ilan J: Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo. Proc Natl Acad Sci USA 93: 7263-7268, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7263-7268
    • Burfeind, P.1    Chernicky, C.L.2    Rininsland, F.3    Ilan, J.4
  • 15
    • 9244242088 scopus 로고    scopus 로고
    • Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model
    • Krueckl SL, Sikes RA, Edlund NM, Bell RH, Hurtado-Coll A, Fazli L, Gleave ME and Cox ME: Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model. Cancer Res 64: 8620-8629, 2004.
    • (2004) Cancer Res , vol.64 , pp. 8620-8629
    • Krueckl, S.L.1    Sikes, R.A.2    Edlund, N.M.3    Bell, R.H.4    Hurtado-Coll, A.5    Fazli, L.6    Gleave, M.E.7    Cox, M.E.8
  • 16
    • 0035881876 scopus 로고    scopus 로고
    • In vivo progression of LAPC-9 and LNCaP prostate cancer models to androgen independence is associated with increased expression of insulin-like growth factor I (IGF-I) and IGF-I receptor (IGF-IR)
    • Nickerson T, Chang F, Lorimer D, Smeekens SP, Sawyers CL and Pollak M: In vivo progression of LAPC-9 and LNCaP prostate cancer models to androgen independence is associated with increased expression of insulin-like growth factor I (IGF-I) and IGF-I receptor (IGF-IR). Cancer Res 61: 6276-6280, 2001.
    • (2001) Cancer Res , vol.61 , pp. 6276-6280
    • Nickerson, T.1    Chang, F.2    Lorimer, D.3    Smeekens, S.P.4    Sawyers, C.L.5    Pollak, M.6
  • 17
    • 0033135898 scopus 로고    scopus 로고
    • The insulin-like growth factor axis and prostate cancer: Lessons from the transgenic adenocarcinoma of mouse prostate (TRAMP) model
    • Kaplan PJ, Mohan S, Cohen P, Foster BA and Greenberg NM: The insulin-like growth factor axis and prostate cancer: lessons from the transgenic adenocarcinoma of mouse prostate (TRAMP) model. Cancer Res 59: 2203-2209, 1999.
    • (1999) Cancer Res , vol.59 , pp. 2203-2209
    • Kaplan, P.J.1    Mohan, S.2    Cohen, P.3    Foster, B.A.4    Greenberg, N.M.5
  • 20
    • 0037092971 scopus 로고    scopus 로고
    • Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease
    • Hellawell GO, Turner GDH, Davies DR, Poulsom R, Brewster SF and Macaulay VM: Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease. Cancer Res 62: 2942-2950, 2002.
    • (2002) Cancer Res , vol.62 , pp. 2942-2950
    • Hellawell, G.O.1    Turner, G.D.H.2    Davies, D.R.3    Poulsom, R.4    Brewster, S.F.5    Macaulay, V.M.6
  • 21
    • 0036488589 scopus 로고    scopus 로고
    • Role of integrins in cell invasion and migration
    • Hood JD and Cheresh DA: Role of integrins in cell invasion and migration. Nat Rev Cancer 21: 91-100, 2002.
    • (2002) Nat Rev Cancer , vol.21 , pp. 91-100
    • Hood, J.D.1    Cheresh, D.A.2
  • 22
    • 0033118450 scopus 로고    scopus 로고
    • Prostatic carcinoma cell migration via αvβ3 integrin is modulated by a focal adhesion kinase pathway
    • Zheng D-Q, Woorward AS, Fornaro M, Tallini G and Languino LR: Prostatic carcinoma cell migration via αvβ3 integrin is modulated by a focal adhesion kinase pathway. Cancer Res 59: 1655-1664, 1999.
    • (1999) Cancer Res , vol.59 , pp. 1655-1664
    • Zheng, D.-Q.1    Woorward, A.S.2    Fornaro, M.3    Tallini, G.4    Languino, L.R.5
  • 23
    • 0036729025 scopus 로고    scopus 로고
    • Role of the orphan nuclear receptor RORα in the control of the metastatic behavior of androgen-independent prostate cancer cells
    • Moretti RM, Montagnani Marelli M, Motta M and Limonta P: Role of the orphan nuclear receptor RORα in the control of the metastatic behavior of androgen-independent prostate cancer cells. Oncol Rep 9: 1139-1143, 2002.
    • (2002) Oncol Rep , vol.9 , pp. 1139-1143
    • Moretti, R.M.1    Montagnani Marelli, M.2    Motta, M.3    Limonta, P.4
  • 24
    • 4444370976 scopus 로고    scopus 로고
    • Mechanisms by which IGF-I may promote cancer
    • Grimberg A: Mechanisms by which IGF-I may promote cancer. Cancer Biol Ther 2: 630-635, 2003.
    • (2003) Cancer Biol Ther , vol.2 , pp. 630-635
    • Grimberg, A.1
  • 25
    • 0036197909 scopus 로고    scopus 로고
    • Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and DU145 prostate carcinoma cells
    • Klein RD and Fischer SM: Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and DU145 prostate carcinoma cells. Carcinogenesis 23: 217-221, 2002.
    • (2002) Carcinogenesis , vol.23 , pp. 217-221
    • Klein, R.D.1    Fischer, S.M.2
  • 26
    • 0032894222 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF) receptor blockade inhibits the action of EGF, insulin-like growth factor I and protein kinase A activator on the mitogen-activated protein kinase pathway in prostate cancer cell lines
    • Putz T, Culig Z, Eder IE, Nessler-Menardi C, Bartsch G, Grunicke H, Uberall F and Klocker H: Epidermal growth factor (EGF) receptor blockade inhibits the action of EGF, insulin-like growth factor I and protein kinase A activator on the mitogen-activated protein kinase pathway in prostate cancer cell lines. Cancer Res 59: 227-233, 1999.
    • (1999) Cancer Res , vol.59 , pp. 227-233
    • Putz, T.1    Culig, Z.2    Eder, I.E.3    Nessler-Menardi, C.4    Bartsch, G.5    Grunicke, H.6    Uberall, F.7    Klocker, H.8
  • 28
    • 0346656569 scopus 로고    scopus 로고
    • Blockade of the type I IGF receptor expression in human prostate cancer cells inhibits proliferation and invasion, up-regulates IGF binding protein-3 and suppresses MMP-2 expression
    • Grzmil M, Hemmerlein B, Thelen P, Schweyer S and Burfeind P: Blockade of the type I IGF receptor expression in human prostate cancer cells inhibits proliferation and invasion, up-regulates IGF binding protein-3 and suppresses MMP-2 expression. J Pathol 202: 50-59, 2004.
    • (2004) J Pathol , vol.202 , pp. 50-59
    • Grzmil, M.1    Hemmerlein, B.2    Thelen, P.3    Schweyer, S.4    Burfeind, P.5
  • 29
    • 10344222098 scopus 로고    scopus 로고
    • The therapeutic potential of agents targeting the type I insulin-like growth factor receptor
    • Zhang H and Yee D: The therapeutic potential of agents targeting the type I insulin-like growth factor receptor. Exp Opin Invest Drugs 13: 1569-1577, 2004.
    • (2004) Exp Opin Invest Drugs , vol.13 , pp. 1569-1577
    • Zhang, H.1    Yee, D.2
  • 30
    • 0035504405 scopus 로고    scopus 로고
    • Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines
    • Jackson JG, Zhang X, Yoneda Y and Yee D: Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines. Oncogene 20: 7318-7325, 2001.
    • (2001) Oncogene , vol.20 , pp. 7318-7325
    • Jackson, J.G.1    Zhang, X.2    Yoneda, Y.3    Yee, D.4
  • 31
    • 1842833905 scopus 로고    scopus 로고
    • Functional role of alpha-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells
    • Guvakova MA, Adams JC and Boettiger D: Functional role of alpha-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells. J Cell Sci 115: 4149-4165, 2002.
    • (2002) J Cell Sci , vol.115 , pp. 4149-4165
    • Guvakova, M.A.1    Adams, J.C.2    Boettiger, D.3
  • 32
    • 0032146711 scopus 로고    scopus 로고
    • A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion and metastasis of breast cancer
    • Dunn SE, Ehrlich M, Sharp NJ, Reiss K, Solomon G, Hawkins R, Baserga R and Barrett JC: A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion and metastasis of breast cancer. Cancer Res 58: 3353-3361, 1998.
    • (1998) Cancer Res , vol.58 , pp. 3353-3361
    • Dunn, S.E.1    Ehrlich, M.2    Sharp, N.J.3    Reiss, K.4    Solomon, G.5    Hawkins, R.6    Baserga, R.7    Barrett, J.C.8
  • 33
    • 1042301373 scopus 로고    scopus 로고
    • A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells
    • Sachdev D, Hartell JS, Lee AV, Zhang X and Yee D: A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells. J Biol Chem 279: 5017-5024, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 5017-5024
    • Sachdev, D.1    Hartell, J.S.2    Lee, A.V.3    Zhang, X.4    Yee, D.5
  • 35
    • 0036173548 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis
    • Wu Y, Yakar S, Zhao L, Hennighausen L and LeRoith D: Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis. Cancer Res 62: 1030-1035, 2002.
    • (2002) Cancer Res , vol.62 , pp. 1030-1035
    • Wu, Y.1    Yakar, S.2    Zhao, L.3    Hennighausen, L.4    LeRoith, D.5
  • 36
    • 20944451167 scopus 로고    scopus 로고
    • Insulin-like growth factor-I-mediated migration and invasion of human colon carcinoma cells requires activation of c-Met and urokinase plasminogen activator receptor
    • Bauer TW, Fan F, Liu W, Johnson M, Parikh NU, Parry GC, Callahan J, Mazar AP, Gallick GE and Ellis LM: Insulin-like growth factor-I-mediated migration and invasion of human colon carcinoma cells requires activation of c-Met and urokinase plasminogen activator receptor. Ann Surg 241: 748-758, 2005.
    • (2005) Ann Surg , vol.241 , pp. 748-758
    • Bauer, T.W.1    Fan, F.2    Liu, W.3    Johnson, M.4    Parikh, N.U.5    Parry, G.C.6    Callahan, J.7    Mazar, A.P.8    Gallick, G.E.9    Ellis, L.M.10
  • 37
    • 0842290053 scopus 로고    scopus 로고
    • Growth factor-enhanced expression and activity of matrix metalloproteases in human non-small cell lung cancer cell lines
    • Bredin CG, Liu Z and Klominek J: Growth factor-enhanced expression and activity of matrix metalloproteases in human non-small cell lung cancer cell lines. Anticancer Res 23: 4877-4884, 2003.
    • (2003) Anticancer Res , vol.23 , pp. 4877-4884
    • Bredin, C.G.1    Liu, Z.2    Klominek, J.3
  • 38
    • 2442673123 scopus 로고    scopus 로고
    • Loss of tumorigenicity and metastatic potential in carcinoma cells expressing the extracellular domain of the type 1 insulin-like growth factor receptor
    • Samani AA, Chevet E, Fallavollita L, Galipeau J and Brodt P: Loss of tumorigenicity and metastatic potential in carcinoma cells expressing the extracellular domain of the type 1 insulin-like growth factor receptor. Cancer Res 64: 3380-3385, 2004.
    • (2004) Cancer Res , vol.64 , pp. 3380-3385
    • Samani, A.A.1    Chevet, E.2    Fallavollita, L.3    Galipeau, J.4    Brodt, P.5
  • 39
    • 2442421050 scopus 로고    scopus 로고
    • Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: The phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals
    • Zhang D, Bar-Eli M, Meloche S and Brodt P: Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals. J Biol Chem 279: 19683-19690, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 19683-19690
    • Zhang, D.1    Bar-Eli, M.2    Meloche, S.3    Brodt, P.4
  • 41
    • 0034637509 scopus 로고    scopus 로고
    • Substrate specificity of αvβ3 integrin-mediated cell migration and phosphatidylinositol 3-kinase/AKT
    • Zheng DQ, Woodard AS, Tallini G and Languino LR: Substrate specificity of αvβ3 integrin-mediated cell migration and phosphatidylinositol 3-kinase/AKT. J Biol Chem 275: 24565-24574, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 24565-24574
    • Zheng, D.Q.1    Woodard, A.S.2    Tallini, G.3    Languino, L.R.4
  • 42
    • 0033237660 scopus 로고    scopus 로고
    • Synthetic alphaVbeta3 antagonists inhibit insulin-like growth factor-I-stimulated smooth muscle cell migration and replication
    • Clemmons DR, Horvitz G, Engleman W, Nichols T, Moralez A and Nickols GA: Synthetic alphaVbeta3 antagonists inhibit insulin-like growth factor-I-stimulated smooth muscle cell migration and replication. Endocrinology 140: 4616-4621, 1999.
    • (1999) Endocrinology , vol.140 , pp. 4616-4621
    • Clemmons, D.R.1    Horvitz, G.2    Engleman, W.3    Nichols, T.4    Moralez, A.5    Nickols, G.A.6
  • 44
    • 22444440288 scopus 로고    scopus 로고
    • αvβ3 integrins and Pyk2 mediate IGF-I activation of Src and MAPK in 3T3-L1 cells
    • Sekimoto H, Eipper-Mains J, Pond-Tor S and Boney CM: αvβ3 integrins and Pyk2 mediate IGF-I activation of Src and MAPK in 3T3-L1 cells. Mol Endocrinol 19: 1859-1867, 2005.
    • (2005) Mol Endocrinol , vol.19 , pp. 1859-1867
    • Sekimoto, H.1    Eipper-Mains, J.2    Pond-Tor, S.3    Boney, C.M.4
  • 45
    • 0036826862 scopus 로고    scopus 로고
    • The alphaVbeta3 integrin regulates insulin-like growth factor I (IGF-I) receptor phosphorylation by altering the rate of recruitment of the Src-homology 2-containing phosphotyrosine phosphatase-2 to the activated IGF-I receptor
    • Maile LA and Clemmons DR: The alphaVbeta3 integrin regulates insulin-like growth factor I (IGF-I) receptor phosphorylation by altering the rate of recruitment of the Src-homology 2-containing phosphotyrosine phosphatase-2 to the activated IGF-I receptor. Endocrinology 143: 4259-4264, 2002.
    • (2002) Endocrinology , vol.143 , pp. 4259-4264
    • Maile, L.A.1    Clemmons, D.R.2
  • 46
    • 0042334863 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the beta3-subunit of the alphaVbeta3 integrin is required for membrane association of the tyrosine phosphatase SHP-2 and its further recruitment to the insulin-like growth factor I receptor
    • Ling Y, Maile LA and Clemmons DR: Tyrosine phosphorylation of the beta3-subunit of the alphaVbeta3 integrin is required for membrane association of the tyrosine phosphatase SHP-2 and its further recruitment to the insulin-like growth factor I receptor. Mol Endocrinol 17: 1824-1833, 2003.
    • (2003) Mol Endocrinol , vol.17 , pp. 1824-1833
    • Ling, Y.1    Maile, L.A.2    Clemmons, D.R.3
  • 47
    • 13544270759 scopus 로고    scopus 로고
    • DOK1 mediates SHP-2 binding to the alphaVbeta3 integrin and thereby regulates insulin-like growth factor I signalling in cultured vascular smooth muscle cells
    • Ling Y, Maile LA, Badley-Clarke J and Clemmons DR: DOK1 mediates SHP-2 binding to the alphaVbeta3 integrin and thereby regulates insulin-like growth factor I signalling in cultured vascular smooth muscle cells. J Biol Chem 280: 3151-3158, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 3151-3158
    • Ling, Y.1    Maile, L.A.2    Badley-Clarke, J.3    Clemmons, D.R.4
  • 48
    • 0842282618 scopus 로고    scopus 로고
    • Bimolecular interaction of insulin-like growth factor (IGF) binding protein-2 with αvβ3 negatively modulates IGF-I-mediated migration and tumor growth
    • Pereira JJ, Meyer T, Docherty SE, Reid HH, Marshall J, Thompson EW, Rossjohn J and Price JT: Bimolecular interaction of insulin-like growth factor (IGF) binding protein-2 with αvβ3 negatively modulates IGF-I-mediated migration and tumor growth. Cancer Res 64: 977-984, 2004.
    • (2004) Cancer Res , vol.64 , pp. 977-984
    • Pereira, J.J.1    Meyer, T.2    Docherty, S.E.3    Reid, H.H.4    Marshall, J.5    Thompson, E.W.6    Rossjohn, J.7    Price, J.T.8


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