-
1
-
-
3543035771
-
Biology and therapeutic advances for pediatric osteosarcoma
-
DOI 10.1634/theoncologist.9-4-422
-
Marina N, Gebhardt M, Teot L, Gorlick R: Biology and therapeutic advances for pediatric osteosarcoma. Oncologist 9(4), 422-441 (2004). (Pubitemid 39014554)
-
(2004)
Oncologist
, vol.9
, Issue.4
, pp. 422-441
-
-
Marina, N.1
Gebhardt, M.2
Teot, L.3
Gorlick, R.4
-
2
-
-
47549083691
-
Changes in incidence and survival of Ewing sarcoma patients over the past 3 decades: Surveillance epidemiology and end results data
-
Esiashvili N, Goodman M, Marcus RB Jr: Changes in incidence and survival of Ewing sarcoma patients over the past 3 decades: surveillance epidemiology and end results data. J. Pediatr. Hematol. Oncol. 30(6), 425-430 (2008).
-
(2008)
J. Pediatr. Hematol. Oncol.
, vol.30
, Issue.6
, pp. 425-430
-
-
Esiashvili, N.1
Goodman, M.2
Marcus Jr., R.B.3
-
3
-
-
61449097712
-
The role of IGF-1R in pediatric malignancies
-
Kim SY, Toretsky JA, Scher D, Helman LJ: The role of IGF-1R in pediatric malignancies. Oncologist 14(1), 83-91 (2009).
-
(2009)
Oncologist
, vol.14
, Issue.1
, pp. 83-91
-
-
Kim, S.Y.1
Toretsky, J.A.2
Scher, D.3
Helman, L.J.4
-
4
-
-
0028900684
-
Insulin-like growth factor 1 (IGF-1) receptors, IGF-1, and IGF-2 are expressed in primary human sarcomas
-
Sekyi-Otu A, Bell RS, Ohashi C, Pollak M, Andrulis IL: Insulin-like growth factor 1 (IGF-1) receptors, IGF-1, and IGF-2 are expressed in primary human sarcomas. Cancer Res. 55(1), 129-134 (1995).
-
(1995)
Cancer Res
, vol.55
, Issue.1
, pp. 129-134
-
-
Sekyi-Otu, A.1
Bell, R.S.2
Ohashi, C.3
Pollak, M.4
Andrulis, I.L.5
-
5
-
-
0029433537
-
Role of insulin-like growth factor binding proteins in the control of IGF actions
-
Clemmons DR, Busby WH, Arai T et al.: Role of insulin-like growth factor binding proteins in the control of IGF actions. Prog. Growth Factor Res. 6(2-4), 357-366 (1995).
-
(1995)
Prog. Growth Factor Res.
, vol.6
, Issue.2-4
, pp. 357-366
-
-
Clemmons, D.R.1
Busby, W.H.2
Arai, T.3
-
6
-
-
0031743951
-
Insulin-like growth factor-I receptor signal transduction: At the interface between physiology and cell biology
-
DOI 10.1016/S0305-0491(98)10106-2, PII S0305049198101062
-
Butler AA, Yakar S, Gewolb IH, Karas M, Okubo Y, LeRoith D: Insulin-like growth factor-I receptor signal transduction: at the interface between physiology and cell biology. Comp. Biochem. Physiol. B. Biochem. Mol. Biol. 121(1), 19-26 (1998). (Pubitemid 28561545)
-
(1998)
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology
, vol.121
, Issue.1
, pp. 19-26
-
-
Butler, A.A.1
Yakar, S.2
Gewolb, I.H.3
Karas, M.4
Okubo, Y.5
LeRoith, D.6
-
7
-
-
0028115727
-
Specific expression of insulin-like growth factor-II in rhabdomyosarcoma tumor cells
-
Minniti CP, Tsokos M, Newton WA Jr, Helman LJ: Specific expression of insulin-like growth factor-II in rhabdomyosarcoma tumor cells. Am. J. Clin. Pathol. 101(2), 198-203 (1994). (Pubitemid 24061448)
-
(1994)
American Journal of Clinical Pathology
, vol.101
, Issue.2
, pp. 198-203
-
-
Minniti, C.P.1
Tsokos, M.2
Newton Jr., W.A.3
Helman, L.J.4
-
8
-
-
0032189704
-
Insulin-like growth factor II and PAX3-FKHR cooperate in the oncogenesis of rhabdomyosarcoma
-
Wang W, Kumar P, Epstein J, Helman L, Moore JV, Kumar S: Insulin-like growth factor II and PAX3-FKHR cooperate in the oncogenesis of rhabdomyosarcoma. Cancer Res. 58(19), 4426-4433 (1998). (Pubitemid 28450047)
-
(1998)
Cancer Research
, vol.58
, Issue.19
, pp. 4426-4433
-
-
Wang, W.1
Kumar, P.2
Wang, W.3
Epstein, J.4
Helman, L.5
Moore, J.V.6
Kumar, S.7
-
9
-
-
0029588595
-
Loss of imprinting of IGF2 in Ewing's sarcoma
-
Zhan S, Shapiro DN, Helman LJ: Loss of imprinting of IGF2 in Ewing's sarcoma. Oncogene 11(12), 2503-2507 (1995). (Pubitemid 26023817)
-
(1995)
Oncogene
, vol.11
, Issue.12
, pp. 2503-2507
-
-
Zhan, S.1
Shapiro, D.N.2
Helman, L.J.3
-
10
-
-
0026446058
-
A new marker for rhabdomyosarcoma. Insulin-like growth factor II
-
Yun K: A new marker for rhabdomyosarcoma. Insulin-like growth factor II. Lab. Invest. 67(5), 653-664 (1992).
-
(1992)
Lab. Invest.
, vol.67
, Issue.5
, pp. 653-664
-
-
Yun, K.1
-
11
-
-
54249157471
-
Addiction to elevated insulin-like growth factor i receptor and initial modulation of the Akt pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody
-
Cao L, Yu Y, Darko I et al.: Addiction to elevated insulin-like growth factor I receptor and initial modulation of the Akt pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody. Cancer Res. 68(19), 8039-8048 (2008).
-
(2008)
Cancer Res
, vol.68
, Issue.19
, pp. 8039-8048
-
-
Cao, L.1
Yu, Y.2
Darko, I.3
-
12
-
-
63449142234
-
Expression of insulin-like growth factor pathway proteins in rhabdomyosarcoma: IGF-2 expression is associated with translocation-negative tumors
-
Makawita S, Ho M, Durbin AD, Thorner PS, Malkin D, Somers GR: Expression of insulin-like growth factor pathway proteins in rhabdomyosarcoma: IGF-2 expression is associated with translocation-negative tumors. Pediatr. Dev. Pathol. 12(2), 127-135 (2009).
-
(2009)
Pediatr. Dev. Pathol.
, vol.12
, Issue.2
, pp. 127-135
-
-
Makawita, S.1
Ho, M.2
Durbin, A.D.3
Thorner, P.S.4
Malkin, D.5
Somers, G.R.6
-
13
-
-
0035728324
-
Transcriptional regulation of IGF-I receptor gene expression by the PAX3-FKHR oncoprotein
-
DOI 10.1054/ghir.2001.0244
-
Ayalon D, Glaser T, Werner H: Transcriptional regulation of IGF-I receptor gene expression by the PAX3-FKHR oncoprotein. Growth Horm. IGF Res. 11(5), 289-297 (2001). (Pubitemid 34257726)
-
(2001)
Growth Hormone and IGF Research
, vol.11
, Issue.5
, pp. 289-297
-
-
Ayalon, D.1
Glaser, T.2
Werner, H.3
-
14
-
-
42349083307
-
Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program
-
DOI 10.1002/pbc.21450
-
Kolb EA, Gorlick R, Houghton PJ et al.: Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program. Pediatr. Blood Cancer 50(6), 1190-1197 (2008). (Pubitemid 351555543)
-
(2008)
Pediatric Blood and Cancer
, vol.50
, Issue.6
, pp. 1190-1197
-
-
Anders Kolb, E.1
Gorlick, R.2
Houghton, P.J.3
Morton, C.L.4
Lock, R.5
Carol, H.6
Patrick Reynolds, C.7
Maris, J.M.8
Keir, S.T.9
Billups, C.A.10
Smith, M.A.11
-
15
-
-
0035839938
-
Biology of EWS/ETS fusions in Ewing's family tumors
-
Arvand A, Denny CT: Biology of EWS/ETS fusions in Ewing's family tumors. Oncogene 20(40), 5747-5754 (2001).
-
(2001)
Oncogene
, vol.20
, Issue.40
, pp. 5747-5754
-
-
Arvand, A.1
Denny, C.T.2
-
16
-
-
0035575779
-
Insulin-like growth factor type 1 (IGF-1) and igf binding protein-3 in patients with ewing sarcoma family of tumors
-
DOI 10.1002/1097-0142(20011201)92:11<2941::AID-CNCR10072>3.0.CO;2-C
-
Toretsky JA, Steinberg SM, Thakar M et al.: Insulin-like growth factor type 1 (IGF-1) and IGF binding protein-3 in patients with Ewing sarcoma family of tumors. Cancer 92(11), 2941-2947 (2001). (Pubitemid 33091932)
-
(2001)
Cancer
, vol.92
, Issue.11
, pp. 2941-2947
-
-
Schouten-van Meeteren, A.Y.N.1
Van Valk, P.D.2
Van Der Linden, H.C.3
Moll, A.C.4
Imhof, S.M.5
Huismans, D.R.6
Loonen, A.H.7
Veerman, A.J.P.8
-
17
-
-
0025632981
-
Insulin-like growth factor i expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factor
-
Yee D, Favoni RE, Lebovic GS et al.: Insulin-like growth factor I expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factor. J. Clin. Invest. 86(6), 1806-1814 (1990).
-
(1990)
J. Clin. Invest.
, vol.86
, Issue.6
, pp. 1806-1814
-
-
Yee, D.1
Favoni, R.E.2
Lebovic, G.S.3
-
18
-
-
62849105383
-
The insulin-like growth factor system and sarcomas
-
Rikhof B, De Jong S, Suurmeijer AJ, Meijer C, van der Graaf WT: The insulin-like growth factor system and sarcomas. J. Pathol. 217(4), 469-482 (2009).
-
(2009)
J. Pathol.
, vol.217
, Issue.4
, pp. 469-482
-
-
Rikhof, B.1
De Jong, S.2
Suurmeijer, A.J.3
Meijer, C.4
Van Der Graaf, W.T.5
-
19
-
-
0031704545
-
Expression of insulin-like growth factor receptor, IGF-1, and IGF-2 in primary and metastatic osteosarcoma
-
DOI 10.1002/(SICI)1096-9098(199809)69:1<21::AID-JSO5>3.0.CO;2-M
-
Burrow S, Andrulis IL, Pollak M, Bell RS: Expression of insulin-like growth factor receptor, IGF-1, and IGF-2 in primary and metastatic osteosarcoma. J. Surg. Oncol. 69(1), 21-27 (1998). (Pubitemid 28452269)
-
(1998)
Journal of Surgical Oncology
, vol.69
, Issue.1
, pp. 21-27
-
-
Burrow, S.1
Andrulis, I.L.2
Pollak, M.3
Bell, R.S.4
-
20
-
-
65549161522
-
Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma
-
Avnet S, Sciacca L, Salerno M et al.: Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma. Cancer Res. 69(6), 2443-2452 (2009).
-
(2009)
Cancer Res
, vol.69
, Issue.6
, pp. 2443-2452
-
-
Avnet, S.1
Sciacca, L.2
Salerno, M.3
-
21
-
-
34548078061
-
Analysis of genes critical for growth regulation identifies insulin-like growth factor 2 receptor variations with possible functional significance as risk factors for osteosarcoma
-
DOI 10.1158/1055-9965.EPI-07-0214
-
Savage SA, Woodson K, Walk E et al.: Analysis of genes critical for growth regulation identifies insulin-like growth factor 2 receptor variations with possible functional significance as risk factors for osteosarcoma. Cancer Epidemiol Biomarkers Prev. 16(8), 1667-1674 (2007). (Pubitemid 47294836)
-
(2007)
Cancer Epidemiology Biomarkers and Prevention
, vol.16
, Issue.8
, pp. 1667-1674
-
-
Savage, S.A.1
Woodson, K.2
Walk, E.3
Modi, W.4
Liao, J.5
Douglass, C.6
Hoover, R.N.7
Chanock, S.J.8
Simon, M.A.9
Gebhardt, M.C.10
Scarborough, M.T.11
Gitelis, S.12
Eckardt, J.J.13
Neff, J.R.14
Joyce, M.J.15
Malawer, M.16
McGuire, M.17
Anderson, H.C.18
-
22
-
-
0026721016
-
Inhibition of metastatic behavior of murine osteosarcoma by hypophysectomy
-
Pollak M, Sem AW, Richard M, Tetenes E, Bell R: Inhibition of metastatic behavior of murine osteosarcoma by hypophysectomy. J. Natl Cancer Inst. 84(12), 966-971 (1992).
-
(1992)
J. Natl Cancer Inst.
, vol.84
, Issue.12
, pp. 966-971
-
-
Pollak, M.1
Sem, A.W.2
Richard, M.3
Tetenes, E.4
Bell, R.5
-
23
-
-
33750312177
-
The synovial-sarcoma-associated SS18-SSX2 fusion protein induces epigenetic gene (de)regulation
-
De Bruijn DR, Allander SV, van Dijk AH et al.: The synovial-sarcoma- associated SS18-SSX2 fusion protein induces epigenetic gene (de)regulation. Cancer Res. 66(19), 9474-9482 (2006).
-
(2006)
Cancer Res
, vol.66
, Issue.19
, pp. 9474-9482
-
-
De Bruijn, D.R.1
Allander, S.V.2
Van Dijk, A.H.3
-
24
-
-
57149093206
-
Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma
-
Friedrichs N, Kuchler J, Endl E et al.: Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma. J. Pathol. 216(4), 428-439 (2008).
-
(2008)
J. Pathol.
, vol.216
, Issue.4
, pp. 428-439
-
-
Friedrichs, N.1
Kuchler, J.2
Endl, E.3
-
25
-
-
0033179378
-
Expression of insulin-like growth factor-1 receptor in synovial sarcoma: Association with an aggressive phenotype
-
Xie Y, Skytting B, Nilsson G, Brodin B, Larsson O: Expression of insulin-like growth factor-1 receptor in synovial sarcoma: association with an aggressive phenotype. Cancer Res. 59(15), 3588-3591 (1999). (Pubitemid 29381857)
-
(1999)
Cancer Research
, vol.59
, Issue.15
, pp. 3588-3591
-
-
Xie, Y.1
Skytting, B.2
Nilsson, G.3
Brodin, B.4
Larsson, O.5
-
26
-
-
33845630749
-
A novel EWS-WT1 gene fusion product in desmoplastic small round cell tumor is a potent transactivator of the insulin-like growth factor-I receptor (IGF-IR) gene
-
DOI 10.1016/j.canlet.2006.03.027, PII S030438350600190X
-
Werner H, Idelman G, Rubinstein M, Pattee P, Nagalla SR, Roberts CT Jr: A novel EWS-WT1 gene fusion product in desmoplastic small round cell tumor is a potent transactivator of the insulin-like growth factor-I receptor (IGF-IR) gene. Cancer Lett. 247(1), 84-90 (2007). (Pubitemid 44959411)
-
(2007)
Cancer Letters
, vol.247
, Issue.1-2
, pp. 84-90
-
-
Werner, H.1
Idelman, G.2
Rubinstein, M.3
Pattee, P.4
Nagalla, S.R.5
Roberts Jr., C.T.6
-
27
-
-
20944447905
-
Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors
-
DOI 10.1158/0008-5472.CAN-04-3192
-
Scotlandi K, Manara MC, Nicoletti G et al.: Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors. Cancer Res. 65(9), 3868-3876 (2005). (Pubitemid 40616368)
-
(2005)
Cancer Research
, vol.65
, Issue.9
, pp. 3868-3876
-
-
Scotlandi, K.1
Manara, M.C.2
Nicoletti, G.3
Lollini, P.-L.4
Lukas, S.5
Benini, S.6
Croci, S.7
Perdichizzi, S.8
Zambelli, D.9
Serra, M.10
Garcia-Echeverria, C.11
Hofmann, F.12
Picci, P.13
-
28
-
-
33745212417
-
Insulin-like growth factor i receptor pathway inhibition by ADW742, alone or in combination with imatinib, doxorubicin, or vincristine, is a novel therapeutic approach in Ewing tumor
-
Martins AS, Mackintosh C, Martin DH et al.: Insulin-like growth factor I receptor pathway inhibition by ADW742, alone or in combination with imatinib, doxorubicin, or vincristine, is a novel therapeutic approach in Ewing tumor. Clin. Cancer Res. 12(11 Pt 1), 3532-3540 (2006).
-
(2006)
Clin. Cancer Res.
, vol.12
, Issue.11 PART 1
, pp. 3532-3540
-
-
Martins, A.S.1
MacKintosh, C.2
Martin, D.H.3
-
29
-
-
51049098720
-
A pivotal role for heat shock protein 90 in Ewing sarcoma resistance to anti-insulin-like growth factor 1 receptor treatment: In vitro and in vivo study
-
Martins AS, Ordonez JL, Garcia-Sanchez A et al.: A pivotal role for heat shock protein 90 in Ewing sarcoma resistance to anti-insulin-like growth factor 1 receptor treatment: in vitro and in vivo study. Cancer Res. 68(15), 6260-6270 (2008).
-
(2008)
Cancer Res
, vol.68
, Issue.15
, pp. 6260-6270
-
-
Martins, A.S.1
Ordonez, J.L.2
Garcia-Sanchez, A.3
-
30
-
-
58249101005
-
The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors
-
Huang F, Greer A, Hurlburt W et al.: The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors. Cancer Res. 69(1), 161-170 (2009).
-
(2009)
Cancer Res
, vol.69
, Issue.1
, pp. 161-170
-
-
Huang, F.1
Greer, A.2
Hurlburt, W.3
-
31
-
-
70349982602
-
Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: Implications for cellular potency and selectivity over insulin receptor
-
Wood ER, Shewchuk L, Hassel A et al.: Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: implications for cellular potency and selectivity over insulin receptor. Biochem. Pharmacol. 78(12), 1438-1447 (2009).
-
(2009)
Biochem. Pharmacol.
, vol.78
, Issue.12
, pp. 1438-1447
-
-
Wood, E.R.1
Shewchuk, L.2
Hassel, A.3
-
32
-
-
77950610169
-
A SARC global collaborative PHASE II trial of R1507, a recombinant human monoclonal antibody to the insulin-like growth factor-1 receptor (IGF1R) in patients with recurrent or refractory sarcomas
-
Presented at Miami Beach, FL, USA 5-7 November Abstract
-
Pappo A, Patel S, Crowley J et al.: A SARC global collaborative PHASE II trial of R1507, a recombinant human monoclonal antibody to the insulin-like growth factor-1 receptor (IGF1R) in patients with recurrent or refractory sarcomas. Presented at: CTOS 15th Annual Meeting. Miami Beach, FL, USA, 5-7 November (2009) (Abstract).
-
(2009)
CTOS 15th Annual Meeting
-
-
Pappo, A.1
Patel, S.2
Crowley, J.3
-
33
-
-
70350227313
-
The insulin-like growth factor-1 receptor-targeting antibody, CP-751,871, suppresses tumor-derived VEGF and synergizes with rapamycin in models of childhood sarcoma
-
Kurmasheva RT, Dudkin L, Billups C, Debelenko LV, Morton CL, Houghton PJ: The insulin-like growth factor-1 receptor-targeting antibody, CP-751,871, suppresses tumor-derived VEGF and synergizes with rapamycin in models of childhood sarcoma. Cancer Res. 69(19), 7662-7671 (2009).
-
(2009)
Cancer Res
, vol.69
, Issue.19
, pp. 7662-7671
-
-
Kurmasheva, R.T.1
Dudkin, L.2
Billups, C.3
Debelenko, L.V.4
Morton, C.L.5
Houghton, P.J.6
-
34
-
-
72449159103
-
Targeting insulin-like growth factor type 1 receptor in cancer therapy
-
Atzori F TT, Ionta MT, Massidda B: Targeting insulin-like growth factor type 1 receptor in cancer therapy. Target Oncol. 4(4) 255-266 (2009).
-
(2009)
Target Oncol
, vol.4
, Issue.4
, pp. 255-266
-
-
Atzori, F.T.T.1
Ionta, M.T.2
Massidda, B.3
-
35
-
-
70349734861
-
Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy
-
Ikeda H, Shiojima I, Ozasa Y et al.: Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy. J. Mol. Cell. Cardiol. 47(5), 664-675 (2009).
-
(2009)
J. Mol. Cell. Cardiol.
, vol.47
, Issue.5
, pp. 664-675
-
-
Ikeda, H.1
Shiojima, I.2
Ozasa, Y.3
-
36
-
-
50249186404
-
The effects of growth hormone and insulin-like growth factor-1 on the aging cardiovascular system and its progenitor cells
-
Devin JK, Young PP: The effects of growth hormone and insulin-like growth factor-1 on the aging cardiovascular system and its progenitor cells. Curr. Opin. Invest. Drugs 9(9), 983-992 (2008).
-
(2008)
Curr. Opin. Invest. Drugs
, vol.9
, Issue.9
, pp. 983-992
-
-
Devin, J.K.1
Young, P.P.2
-
37
-
-
13444302623
-
Insulin-like growth factors and coronary heart disease
-
DOI 10.1097/01.crd.0000134914.10407.40
-
Kaplan RC, Strickler HD, Rohan TE, Muzumdar R, Brown DL: Insulin-like growth factors and coronary heart disease. Cardiol. Rev. 13(1), 35-39 (2005). (Pubitemid 40204695)
-
(2005)
Cardiology in Review
, vol.13
, Issue.1
, pp. 35-39
-
-
Kaplan, R.C.1
Strickler, H.D.2
Rohan, T.E.3
Muzumdar, R.4
Brown, D.L.5
-
38
-
-
77952670495
-
Analysis of angiogenesis induced by local IGF-1 expression after myocardial infarction using microSPECT-CT imaging
-
doi:10.1016/j.yjmcc.2009.10.008 , (Epub ahead of print)
-
Dobrucki LW, Tsutsumi Y, Kalinowski L et al.: Analysis of angiogenesis induced by local IGF-1 expression after myocardial infarction using microSPECT-CT imaging. J. Mol. Cell Cardiol. DOI: doi:10.1016/j.yjmcc.2009.10. 008 (2009) (Epub ahead of print).
-
(2009)
J. Mol. Cell Cardiol.
-
-
Dobrucki, L.W.1
Tsutsumi, Y.2
Kalinowski, L.3
-
39
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley LC: The phosphoinositide 3-kinase pathway. Science 296(5573), 1655-1657 (2002).
-
(2002)
Science
, vol.296
, Issue.5573
, pp. 1655-1657
-
-
Cantley, L.C.1
-
40
-
-
0038540963
-
United at last: The tuberous sclerosis complex gene products connect the phosphoinositide 3-kinase/Akt pathway to mammalian target of rapamycin (mTOR) signalling
-
Manning BD, Cantley LC: United at last: the tuberous sclerosis complex gene products connect the phosphoinositide 3-kinase/Akt pathway to mammalian target of rapamycin (mTOR) signalling. Biochem. Soc. Trans. 31(Pt 3), 573-578 (2003).
-
(2003)
Biochem. Soc. Trans.
, vol.31
, Issue.PART 3
, pp. 573-578
-
-
Manning, B.D.1
Cantley, L.C.2
-
41
-
-
34248216623
-
Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival
-
DOI 10.1158/0008-5472.CAN-06-1344
-
Petricoin EF 3rd, Espina V, Araujo RP et al.: Phosphoprotein pathway mapping: Akt/ mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival. Cancer Res. 67(7), 3431-3440 (2007). (Pubitemid 46724884)
-
(2007)
Cancer Research
, vol.67
, Issue.7
, pp. 3431-3440
-
-
Petricoin III, E.F.1
Espina, V.2
Araujo, R.P.3
Midura, B.4
Yeung, C.5
Wan, X.6
Eichler, G.S.7
Johann Jr., D.J.8
Qualman, S.9
Tsokos, M.10
Krishnan, K.11
Helman, L.J.12
Liotta, L.A.13
-
42
-
-
0028328655
-
Rapamycin selectively inhibits the growth of childhood rhabdomyosarcoma cells through inhibition of signaling via the type I insulin-like growth factor receptor
-
Dilling MB, Dias P, Shapiro DN, Germain GS, Johnson RK, Houghton PJ: Rapamycin selectively inhibits the growth of childhood rhabdomyosarcoma cells through inhibition of signaling via the type I insulin-like growth factor receptor. Cancer Res. 54(4), 903-907 (1994). (Pubitemid 24085438)
-
(1994)
Cancer Research
, vol.54
, Issue.4
, pp. 903-907
-
-
Dilling, M.B.1
Dias, P.2
Shapiro, D.N.3
Germain, G.S.4
Johnson, R.K.5
Houghton, P.J.6
-
43
-
-
40449091406
-
Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program
-
DOI 10.1002/pbc.21296
-
Houghton PJ, Morton CL, Kolb EA et al.: Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program. Pediatr. Blood Cancer 50(4), 799-805 (2008). (Pubitemid 351354788)
-
(2008)
Pediatric Blood and Cancer
, vol.50
, Issue.4
, pp. 799-805
-
-
Houghton, P.J.1
Morton, C.L.2
Kolb, E.A.3
Gorlick, R.4
Lock, R.5
Carol, H.6
Reynolds, C.P.7
Maris, J.M.8
Keir, S.T.9
Billups, C.A.10
Smith, M.A.11
-
44
-
-
16844366544
-
Rapamycin inhibits ezrin-mediated metastatic behavior in a murine model of osteosarcoma
-
DOI 10.1158/0008-5472.CAN-04-3135
-
Wan X, Mendoza A, Khanna C, Helman LJ: Rapamycin inhibits ezrin-mediated metastatic behavior in a murine model of osteosarcoma. Cancer Res. 65(6), 2406-2411 (2005). (Pubitemid 40490152)
-
(2005)
Cancer Research
, vol.65
, Issue.6
, pp. 2406-2411
-
-
Wan, X.1
Mendoza, A.2
Khanna, C.3
Helman, L.J.4
-
45
-
-
59449111147
-
Inhibition of mTOR radiosensitizes soft tissue sarcoma and tumor vasculature
-
Murphy JD, Spalding AC, Somnay YR, Markwart S, Ray ME, Hamstra DA: Inhibition of mTOR radiosensitizes soft tissue sarcoma and tumor vasculature. Clin. Cancer Res. 15(2), 589-596 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, Issue.2
, pp. 589-596
-
-
Murphy, J.D.1
Spalding, A.C.2
Somnay, Y.R.3
Markwart, S.4
Ray, M.E.5
Hamstra, D.A.6
-
46
-
-
63149129641
-
A Phase i trial to determine the safety, tolerability, and maximum tolerated dose of deforolimus in patients with advanced malignancies
-
Hartford CM, Desai AA, Janisch L et al.: A Phase I trial to determine the safety, tolerability, and maximum tolerated dose of deforolimus in patients with advanced malignancies. Clin. Cancer Res. 15(4), 1428-1434 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, Issue.4
, pp. 1428-1434
-
-
Hartford, C.M.1
Desai, A.A.2
Janisch, L.3
-
47
-
-
58149385663
-
Deforolimus (AP23573) a novel mTOR inhibitor in clinical development
-
Mita M, Sankhala K, Abdel-Karim I, Mita A, Giles F: Deforolimus (AP23573) a novel mTOR inhibitor in clinical development. Expert Opin. Invest. Drugs 17(12), 1947-1954 (2008).
-
(2008)
Expert Opin. Invest. Drugs
, vol.17
, Issue.12
, pp. 1947-1954
-
-
Mita, M.1
Sankhala, K.2
Abdel-Karim, I.3
Mita, A.4
Giles, F.5
-
48
-
-
43249086546
-
Phase i pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors
-
O'Donnell A, Faivre S, Burris HA 3rd et al.: Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors. J. Clin. Oncol. 26(10), 1588-1595 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.10
, pp. 1588-1595
-
-
O'Donnell, A.1
Faivre, S.2
Burris III, H.A.3
-
49
-
-
77950609873
-
Phase I, safety, pharmacokinetic, exploratory biomarker study of intravenous temsirolimus in children with advanced solid tumors
-
Abstract
-
Spunt SL, Grupp S, Vik T: Phase I, safety, pharmacokinetic, exploratory biomarker study of intravenous temsirolimus in children with advanced solid tumors. Am. Soc. Pediatr. Hematol. Oncol. (2007) (Abstract).
-
(2007)
Am. Soc. Pediatr. Hematol. Oncol.
-
-
Spunt, S.L.1
Grupp, S.2
Vik, T.3
-
50
-
-
38649140450
-
Phase i trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with advanced malignancies
-
Mita MM, Mita AC, Chu QS et al.: Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with advanced malignancies. J. Clin. Oncol. 26(3), 361-367 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.3
, pp. 361-367
-
-
Mita, M.M.1
Mita, A.C.2
Chu, Q.S.3
-
51
-
-
33745220580
-
Synergy between an IGF-1R antibody and Raf/MEK/ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells
-
Bertrand FE, Steelman LS, Chappell WH et al.: Synergy between an IGF-1R antibody and Raf/MEK/ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells. Leukemia 20(7), 1254-1260 (2006).
-
(2006)
Leukemia
, vol.20
, Issue.7
, pp. 1254-1260
-
-
Bertrand, F.E.1
Steelman, L.S.2
Chappell, W.H.3
-
52
-
-
33750211376
-
Predicted mechanisms of resistance to mTOR inhibitors
-
Kurmasheva RT, Huang S, Houghton PJ: Predicted mechanisms of resistance to mTOR inhibitors. Br. J. Cancer 95(8), 955-960 (2006).
-
(2006)
Br. J. Cancer
, vol.95
, Issue.8
, pp. 955-960
-
-
Kurmasheva, R.T.1
Huang, S.2
Houghton, P.J.3
-
53
-
-
66149165883
-
Zoledronic acid inhibits both the osteolytic and osteoblastic components of osteosarcoma lesions in a mouse model
-
Labrinidis A, Hay S, Liapis V, Ponomarev V, Findlay DM, Evdokiou A: Zoledronic acid inhibits both the osteolytic and osteoblastic components of osteosarcoma lesions in a mouse model. Clin. Cancer Res. 15(10), 3451-3461 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, Issue.10
, pp. 3451-3461
-
-
Labrinidis, A.1
Hay, S.2
Liapis, V.3
Ponomarev, V.4
Findlay, D.M.5
Evdokiou, A.6
-
54
-
-
0037946792
-
Bisphosphonate mechanism of action
-
Reszka AA, Rodan GA: Bisphosphonate mechanism of action. Curr. Rheumatol. Rep. 5(1), 65-74 (2003).
-
(2003)
Curr. Rheumatol. Rep.
, vol.5
, Issue.1
, pp. 65-74
-
-
Reszka, A.A.1
Rodan, G.A.2
-
55
-
-
33845910925
-
Zoledronic acid activates the DNA S-phase checkpoint and induces osteosarcoma cell death characterized by apoptosis-inducing factor and endonuclease-G translocation independently of p53 and retinoblastoma status
-
DOI 10.1124/mol.106.028837
-
Ory B, Blanchard F, Battaglia S, Gouin F, Redini F, Heymann D: Zoledronic acid activates the DNA S-phase checkpoint and induces osteosarcoma cell death characterized by apoptosis-inducing factor and endonuclease-G translocation independently of p53 and retinoblastoma status. Mol. Pharmacol. 71(1), 333-343 (2007). (Pubitemid 46021003)
-
(2007)
Molecular Pharmacology
, vol.71
, Issue.1
, pp. 333-343
-
-
Ory, B.1
Blanchard, F.2
Battaglia, S.3
Gouin, F.4
Redini, F.5
Heymann, D.6
-
56
-
-
23944446040
-
Zoledronic-acid-induced circulating level modifications of angiogenic factors, metalloproteinases and proinflammatory cytokines in metastatic breast cancer patients
-
DOI 10.1159/000087286
-
Ferretti G, Fabi A, Carlini P et al.: Zoledronic-acid-induced circulating level modifications of angiogenic factors, metalloproteinases and proinflammatory cytokines in metastatic breast cancer patients. Oncology 69(1), 35-43 (2005). (Pubitemid 41207056)
-
(2005)
Oncology
, vol.69
, Issue.1
, pp. 35-43
-
-
Ferretti, G.1
Fabi, A.2
Carlini, P.3
Papaldo, P.4
Fei, P.C.5
Di Cosimo, S.6
Salesi, N.7
Giannarelli, D.8
Alimonti, A.9
Di Cocco, B.10
D'Agosto, G.11
Bordignon, V.12
Trento, E.13
Cognetti, F.14
-
57
-
-
35348839555
-
Zoledronic acid -a multiplicity of anti-cancer action
-
DOI 10.2174/092986707781389600
-
Yuasa T, Kimura S, Ashihara E, Habuchi T, Maekawa T: Zoledronic acid - a multiplicity of anti-cancer action. Curr. Med. Chem. 14(20), 2126-2135 (2007). (Pubitemid 47578153)
-
(2007)
Current Medicinal Chemistry
, vol.14
, Issue.20
, pp. 2126-2135
-
-
Yuasa, T.1
Kimura, S.2
Ashihara, E.3
Habuchi, T.4
Maekawa, T.5
-
58
-
-
28044467108
-
Zoledronic acid suppresses lung metastases and prolongs overall survival of osteosarcoma-bearing mice
-
DOI 10.1002/cncr.21530
-
Ory B, Heymann MF, Kamijo A, Gouin F, Heymann D, Redini F: Zoledronic acid suppresses lung metastases and prolongs overall survival of osteosarcoma-bearing mice. Cancer 104(11), 2522-2529 (2005). (Pubitemid 41691577)
-
(2005)
Cancer
, vol.104
, Issue.11
, pp. 2522-2529
-
-
Ory, B.1
Heymann, M.-F.2
Kamijo, A.3
Gouin, F.4
Heymann, D.5
Redini, F.6
-
59
-
-
0034932935
-
The bisphosphonate pamidronate is a potent inhibitor of human osteosarcoma cell growth in vitro
-
DOI 10.1097/00001813-200106000-00007
-
Sonnemann J, Eckervogt V, Truckenbrod B, Boos J, Winkelmann W, van Valen F: The bisphosphonate pamidronate is a potent inhibitor of human osteosarcoma cell growth in vitro. Anticancer Drugs 12(5), 459-465 (2001). (Pubitemid 32643090)
-
(2001)
Anti-Cancer Drugs
, vol.12
, Issue.5
, pp. 459-465
-
-
Sonnemann, J.1
Eckervogt, V.2
Truckenbrod, B.3
Boos, J.4
Winkelmann, W.5
Van Valen, F.6
-
60
-
-
0036901126
-
Mechanisms of bisphosphonate effects on osteoclasts, tumor cell growth, and metastasis
-
DOI 10.1097/00000421-200212001-00002
-
Green JR, Clezardin P: Mechanisms of bisphosphonate effects on osteoclasts, tumor cell growth, and metastasis. Am. J. Clin. Oncol. 25(6 Suppl. 1), S3-S9 (2002). (Pubitemid 35453651)
-
(2002)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.25
, Issue.SUPPL. 1
-
-
Green, J.R.1
Clezardin, P.2
-
61
-
-
34047129164
-
Growth inhibition and sensitization to cisplatin by zoledronic acid in osteosarcoma cells
-
DOI 10.1016/j.canlet.2006.10.004, PII S030438350600557X
-
Benassi MS, Chiechi A, Ponticelli F et al.: Growth inhibition and sensitization to cisplatin by zoledronic acid in osteosarcoma cells. Cancer Lett. 250(2), 194-205 (2007). (Pubitemid 46529443)
-
(2007)
Cancer Letters
, vol.250
, Issue.2
, pp. 194-205
-
-
Benassi, M.S.1
Chiechi, A.2
Ponticelli, F.3
Pazzaglia, L.4
Gamberi, G.5
Zanella, L.6
Manara, M.C.7
Perego, P.8
Ferrari, S.9
Picci, P.10
-
62
-
-
33846523379
-
Combined effects of a third-generation bisphosphonate, zoledronic acid with other anticancer agents against murine osteosarcoma
-
DOI 10.1038/sj.bjc.6603548, PII 6603548
-
Horie N, Murata H, Kimura S et al.: Combined effects of a third-generation bisphosphonate, zoledronic acid with other anticancer agents against murine osteosarcoma. Br. J. Cancer 96(2), 255-261 (2007). (Pubitemid 46160630)
-
(2007)
British Journal of Cancer
, vol.96
, Issue.2
, pp. 255-261
-
-
Horie, N.1
Murata, H.2
Kimura, S.3
Takeshita, H.4
Sakabe, T.5
Matsui, T.6
Maekawa, T.7
Kubo, T.8
Fushiki, S.9
-
63
-
-
26444574115
-
Zoledronic acid inhibits primary bone tumor growth in Ewing sarcoma
-
DOI 10.1002/cncr.21383
-
Zhou Z, Guan H, Duan X, Kleinerman ES: Zoledronic acid inhibits primary bone tumor growth in Ewing sarcoma. Cancer 104(8), 1713-1720 (2005). (Pubitemid 41437436)
-
(2005)
Cancer
, vol.104
, Issue.8
, pp. 1713-1720
-
-
Zhou, Z.1
Guan, H.2
Duan, X.3
Kleinerman, E.S.4
-
64
-
-
11144336663
-
Proven efficacy of zoledronic acid in the treatment of bone metastases in patients with breast cancer and other malignancies
-
Cameron D: Proven efficacy of zoledronic acid in the treatment of bone metastases in patients with breast cancer and other malignancies. Breast 12(Suppl. 2), S22-S29 (2003). (Pubitemid 40023560)
-
(2003)
Breast
, vol.12
, Issue.SUPPL. 2
-
-
Cameron, D.1
-
65
-
-
10744229392
-
Approval summary for zoledronic acid for treatment of multiple myeloma and cancer bone metastases
-
Ibrahim A, Scher N, Williams G et al.: Approval summary for zoledronic acid for treatment of multiple myeloma and cancer bone metastases. Clin. Cancer Res. 9(7), 2394-2399 (2003).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.7
, pp. 2394-2399
-
-
Ibrahim, A.1
Scher, N.2
Williams, G.3
-
66
-
-
0035312469
-
Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases
-
Berenson JR, Rosen LS, Howell A et al.: Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases. Cancer 91(7), 1191-1200 (2001).
-
(2001)
Cancer
, vol.91
, Issue.7
, pp. 1191-1200
-
-
Berenson, J.R.1
Rosen, L.S.2
Howell, A.3
-
67
-
-
0037277721
-
Efficacy and safety of zoledronic acid in the treatment of bone metastases associated with lung cancer and other solid tumors
-
Rosen LS: Efficacy and safety of zoledronic acid in the treatment of bone metastases associated with lung cancer and other solid tumors. Semin. Oncol. 29(6 Suppl. 21), 28-32 (2002).
-
(2002)
Semin. Oncol.
, vol.29
, Issue.6 SUPPL. 21
, pp. 28-32
-
-
Rosen, L.S.1
-
68
-
-
34848872278
-
Osteonecrosis of the jaw as an adverse bisphosphonate event: Three cases of bone metastatic prostate cancer patients treated with zoledronic acid
-
Garcia Saenz JA, Lopez Tarruella S, Garcia Paredes B, Rodriguez Lajusticia L, Villalobos L, Diaz Rubio E: Osteonecrosis of the jaw as an adverse bisphosphonate event: three cases of bone metastatic prostate cancer patients treated with zoledronic acid. Med. Oral Patol. Oral Cir. Bucal. 12(5), E351-E356 (2007).
-
(2007)
Med. Oral Patol. Oral Cir. Bucal.
, vol.12
, Issue.5
-
-
Garcia Saenz, J.A.1
Lopez Tarruella, S.2
Garcia Paredes, B.3
Rodriguez Lajusticia, L.4
Villalobos, L.5
Diaz Rubio, E.6
-
69
-
-
33645828043
-
Liposomal muramyl tripeptide phosphatidylethanolamine: Targeting and activating macrophages for adjuvant treatment of osteosarcoma
-
Nardin A, Lefebvre ML, Labroquere K, Faure O, Abastado JP: Liposomal muramyl tripeptide phosphatidylethanolamine: targeting and activating macrophages for adjuvant treatment of osteosarcoma. Curr. Cancer Drug Targets 6(2), 123-133 (2006).
-
(2006)
Curr. Cancer Drug Targets
, vol.6
, Issue.2
, pp. 123-133
-
-
Nardin, A.1
Lefebvre, M.L.2
Labroquere, K.3
Faure, O.4
Abastado, J.P.5
-
70
-
-
0026498531
-
Liposomes containing muramyl tripeptide phosphatidylethanolamine (MTP-PE) are excellent adjuvants for induction of an immune response to protein and tumor antigens
-
Ullrich SE, Fidler IJ: Liposomes containing muramyl tripeptide phosphatidylethanolamine (MTP-PE) are excellent adjuvants for induction of an immune response to protein and tumor antigens. J. Leukoc. Biol. 52(5), 489-494 (1992).
-
(1992)
J. Leukoc. Biol.
, vol.52
, Issue.5
, pp. 489-494
-
-
Ullrich, S.E.1
Fidler, I.J.2
-
72
-
-
33745492007
-
Liposomal muramyl tripeptide phosphatidyl ethanolamine: Ifosfamide-containing chemotherapy in osteosarcoma
-
Anderson P: Liposomal muramyl tripeptide phosphatidyl ethanolamine: ifosfamide-containing chemotherapy in osteosarcoma. Future Oncol. 2(3), 333-343 (2006).
-
(2006)
Future Onol
, vol.2
, Issue.3
, pp. 333-343
-
-
Anderson, P.1
-
73
-
-
0028928375
-
Efficacy of liposomal muramyl tripeptide (CGP 19835A) in the treatment of relapsed osteosarcoma
-
Kleinerman ES, Gano JB, Johnston DA, Benjamin RS, Jaffe N: Efficacy of liposomal muramyl tripeptide (CGP 19835A) in the treatment of relapsed osteosarcoma. Am. J. Clin. Oncol. 18(2), 93-99 (1995).
-
(1995)
Am. J. Clin. Oncol.
, vol.18
, Issue.2
, pp. 93-99
-
-
Kleinerman, E.S.1
Gano, J.B.2
Johnston, D.A.3
Benjamin, R.S.4
Jaffe, N.5
-
74
-
-
39149136228
-
Osteosarcoma: The addition of muramyl tripeptide to chemotherapy improves overall survival - A report from the Children's Oncology Group
-
Meyers PA, Schwartz CL, Krailo MD et al.: Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival - a report from the Children's Oncology Group. J. Clin. Oncol. 26(4), 633-638 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.4
, pp. 633-638
-
-
Meyers, P.A.1
Schwartz, C.L.2
Krailo, M.D.3
-
75
-
-
70449369314
-
Addition of muramyl tripeptide to chemotherapy for patients with newly diagnosed metastatic osteosarcoma: A report from the Children's Oncology Group
-
Chou AJ, Kleinerman ES, Krailo MD et al.: Addition of muramyl tripeptide to chemotherapy for patients with newly diagnosed metastatic osteosarcoma: a report from the Children's Oncology Group. Cancer 115(22), 5339-5348 (2009).
-
(2009)
Cancer
, vol.115
, Issue.22
, pp. 5339-5348
-
-
Chou, A.J.1
Kleinerman, E.S.2
Krailo, M.D.3
-
76
-
-
1942446145
-
Treatment of solid sarcomas in immunocompetent mice with novel, oncolytic herpes simplex viruses
-
Sugiura S, Goshima F, Takakuwa H, Sata T, Nakashima T, Nishiyama Y: Treatment of solid sarcomas in immunocompetent mice with novel, oncolytic herpes simplex viruses. Otolaryngol. Head Neck Surg. 130(4), 470-478 (2004).
-
(2004)
Otolaryngol. Head Neck Surg.
, vol.130
, Issue.4
, pp. 470-478
-
-
Sugiura, S.1
Goshima, F.2
Takakuwa, H.3
Sata, T.4
Nakashima, T.5
Nishiyama, Y.6
-
77
-
-
0036694323
-
Differential susceptibility of pediatric sarcoma cells to oncolysis by conditionally replication-competent herpes simplex viruses
-
Bharatan NS, Currier MA, Cripe TP: Differential susceptibility of pediatric sarcoma cells to oncolysis by conditionally replication-competent herpes simplex viruses. J. Pediatr. Hematol. Oncol. 24(6), 447-453 (2002).
-
(2002)
J. Pediatr. Hematol. Oncol.
, vol.24
, Issue.6
, pp. 447-453
-
-
Bharatan, N.S.1
Currier, M.A.2
Cripe, T.P.3
-
78
-
-
15744395384
-
Widespread intratumoral virus distribution with fractionated injection enables local control of large human rhabdomyosarcoma xenografts by oncolytic herpes simplex viruses
-
Currier MA, Adams LC, Mahller YY, Cripe TP: Widespread intratumoral virus distribution with fractionated injection enables local control of large human rhabdomyosarcoma xenografts by oncolytic herpes simplex viruses. Cancer Gene Ther. 12(4), 407-416 (2005).
-
(2005)
Cancer Gene Ther
, vol.12
, Issue.4
, pp. 407-416
-
-
Currier, M.A.1
Adams, L.C.2
Mahller, Y.Y.3
Cripe, T.P.4
-
79
-
-
40149087207
-
Intravenous administration of the conditionally replicative adenovirus Ad5-Delta24RGD induces regression of osteosarcoma lung metastases
-
Graat HC, Van Beusechem VW, Schagen FH et al.: Intravenous administration of the conditionally replicative adenovirus Ad5-Delta24RGD induces regression of osteosarcoma lung metastases. Mol. Cancer 7, 9 (2008).
-
(2008)
Mol. Cancer
, vol.7
, pp. 9
-
-
Graat, H.C.1
Van Beusechem, V.W.2
Schagen, F.H.3
-
80
-
-
54249165981
-
Oncolytic Semliki forest virus vector as a novel candidate against unresectable osteosarcoma
-
Ketola A, Hinkkanen A, Yongabi F et al.: Oncolytic Semliki forest virus vector as a novel candidate against unresectable osteosarcoma. Cancer Res. 68(20), 8342-8350 (2008).
-
(2008)
Cancer Res
, vol.68
, Issue.20
, pp. 8342-8350
-
-
Ketola, A.1
Hinkkanen, A.2
Yongabi, F.3
-
81
-
-
36048935105
-
Seneca Valley virus, a systemically deliverable oncolytic picornavirus, and the treatment of neuroendocrine cancers
-
Reddy PS, Burroughs KD, Hales LM et al.: Seneca Valley virus, a systemically deliverable oncolytic picornavirus, and the treatment of neuroendocrine cancers. J. Natl Cancer Inst. 99(21), 1623-1633 (2007).
-
(2007)
J. Natl Cancer Inst.
, vol.99
, Issue.21
, pp. 1623-1633
-
-
Reddy, P.S.1
Burroughs, K.D.2
Hales, L.M.3
-
83
-
-
36349024510
-
Treatment of invasive retinoblastoma in a murine model using an oncolytic picornavirus
-
Wadhwa L, Hurwitz MY, Chevez-Barrios P, Hurwitz RL: Treatment of invasive retinoblastoma in a murine model using an oncolytic picornavirus. Cancer Res. 67(22), 10653-10656 (2007).
-
(2007)
Cancer Res
, vol.67
, Issue.22
, pp. 10653-10656
-
-
Wadhwa, L.1
Hurwitz, M.Y.2
Chevez-Barrios, P.3
Hurwitz, R.L.4
-
84
-
-
77950619016
-
Systemic administration of reolysin inhibits growth of human sarcoma xenografts alone and in combination with cisplatin and radiation
-
Presented at San Diego, CA, USA 12-16 April, Abstract
-
Gidwani P, Zhang E, Guha C, Liu L, Kolb EA: Systemic administration of reolysin inhibits growth of human sarcoma xenografts alone and in combination with cisplatin and radiation. Presented at: American Association for Cancer Research (AACR) 2008 Annual Meeting. San Diego, CA, USA, 12-16 April (2008) (Abstract).
-
(2008)
American Association for Cancer Research (AACR) 2008 Annual Meeting
-
-
Gidwani, P.1
Zhang, E.2
Guha, C.3
Liu, L.4
Kolb, E.A.5
-
85
-
-
58149252477
-
A Phase i study of intravenous oncolytic reovirus type 3 Dearing in patients with advanced cancer
-
Vidal L, Pandha HS, Yap TA et al.: A Phase I study of intravenous oncolytic reovirus type 3 Dearing in patients with advanced cancer. Clin. Cancer Res. 14(21), 7127-7137 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, Issue.21
, pp. 7127-7137
-
-
Vidal, L.1
Pandha, H.S.2
Yap, T.A.3
-
86
-
-
77950612308
-
A Phase II study of intravenous reolysin (wild type reovorus) in the treatment of patients with bone and soft tissue sarcomas metastatic to the lung
-
Presented at Miami Beach, FL, USA 5-7 November, Abstract
-
Mita A, Sankhala K, Sarantopoulos J et al.: A Phase II study of intravenous reolysin (wild type reovorus) in the treatment of patients with bone and soft tissue sarcomas metastatic to the lung. Presented at: CTOS 15th Annual Meeting. Miami Beach, FL, USA, 5-7 November (2009) (Abstract).
-
(2009)
CTOS 15th Annual Meeting
-
-
Mita, A.1
Sankhala, K.2
Sarantopoulos, J.3
-
88
-
-
66849124862
-
Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: Implications for immune recognition
-
Berghuis D, De Hooge AS, Santos SJ et al.: Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition. J. Pathol. 218(2), 222-231 (2009).
-
(2009)
J. Pathol.
, vol.218
, Issue.2
, pp. 222-231
-
-
Berghuis, D.1
De Hooge, A.S.2
Santos, S.J.3
-
89
-
-
67650091383
-
A high proportion of bone marrow T cells with regulatory phenotype (CD4+CD25hiFoxP3+) in Ewing sarcoma patients is associated with metastatic disease
-
Brinkrolf P, Landmeier S, Altvater B et al.: A high proportion of bone marrow T cells with regulatory phenotype (CD4+CD25hiFoxP3+) in Ewing sarcoma patients is associated with metastatic disease. Int. J. Cancer 125(4), 879-886 (2009).
-
(2009)
Int. J. Cancer
, vol.125
, Issue.4
, pp. 879-886
-
-
Brinkrolf, P.1
Landmeier, S.2
Altvater, B.3
-
90
-
-
2942752408
-
Characterization of CD34+ progenitor-derived dendritic cells pulsed with tumor cell lysate for a vaccination strategy in children with malignant solid tumors and a poor prognosis
-
Ackermann B, Troger A, Glouchkova L, Korholz D, Gobel U, Dilloo D: Characterization of CD34+ progenitor-derived dendritic cells pulsed with tumor cell lysate for a vaccination strategy in children with malignant solid tumors and a poor prognosis. Klin. Padiatr. 216(3), 176-182 (2004).
-
(2004)
Klin. Padiatr.
, vol.216
, Issue.3
, pp. 176-182
-
-
Ackermann, B.1
Troger, A.2
Glouchkova, L.3
Korholz, D.4
Gobel, U.5
Dilloo, D.6
-
91
-
-
50649111902
-
Dendritic cell-Ewing's sarcoma cell hybrids enhance antitumor immunity
-
Guo W, Guo Y, Tang S, Qu H, Zhao H: Dendritic cell-Ewing's sarcoma cell hybrids enhance antitumor immunity. Clin. Orthop. Relat. Res. 466(9), 2176-2183 (2008).
-
(2008)
Clin. Orthop. Relat. Res.
, vol.466
, Issue.9
, pp. 2176-2183
-
-
Guo, W.1
Guo, Y.2
Tang, S.3
Qu, H.4
Zhao, H.5
-
92
-
-
34547764917
-
In vitro induction of immune responses to shared tumor-associated antigens in rhabdomyosarcoma
-
Rodeberg DA, Erskine C, Celis E: In vitro induction of immune responses to shared tumor-associated antigens in rhabdomyosarcoma. J. Pediatr. Surg. 42(8), 1396-1402 (2007).
-
(2007)
J. Pediatr. Surg.
, vol.42
, Issue.8
, pp. 1396-1402
-
-
Rodeberg, D.A.1
Erskine, C.2
Celis, E.3
-
93
-
-
34247595587
-
Immune reconstitution prevents metastatic recurrence of murine osteosarcoma
-
Merchant MS, Melchionda F, Sinha M, Khanna C, Helman L, Mackall CL: Immune reconstitution prevents metastatic recurrence of murine osteosarcoma. Cancer Immunol. Immunother. 56(7), 1037-1046 (2007).
-
(2007)
Cancer Immunol. Immunother.
, vol.56
, Issue.7
, pp. 1037-1046
-
-
Merchant, M.S.1
Melchionda, F.2
Sinha, M.3
Khanna, C.4
Helman, L.5
MacKall, C.L.6
-
94
-
-
33846445664
-
Early lymphocyte recovery as a prognostic indicator for high-risk Ewing sarcoma
-
De Angulo G, Hernandez M, Morales- Arias J et al.: Early lymphocyte recovery as a prognostic indicator for high-risk Ewing sarcoma. J. Pediatr. Hematol. Oncol. 29(1), 48-52 (2007).
-
(2007)
J. Pediatr. Hematol. Oncol.
, vol.29
, Issue.1
, pp. 48-52
-
-
De Angulo, G.1
Hernandez, M.2
Morales- Arias, J.3
-
95
-
-
0035576891
-
Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression
-
Geiger JD, Hutchinson RJ, Hohenkirk LF et al.: Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression. Cancer Res. 61(23), 8513-8519 (2001).
-
(2001)
Cancer Res
, vol.61
, Issue.23
, pp. 8513-8519
-
-
Geiger, J.D.1
Hutchinson, R.J.2
Hohenkirk, L.F.3
-
96
-
-
51049105734
-
A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas
-
Mackall CL, Rhee EH, Read EJ et al.: A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas. Clin. Cancer Res. 14(15), 4850-4858 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, Issue.15
, pp. 4850-4858
-
-
MacKall, C.L.1
Rhee, E.H.2
Read, E.J.3
-
97
-
-
65249173447
-
Adoptive cell therapy for the treatment of patients with metastatic melanoma
-
Rosenberg SA, Dudley ME: Adoptive cell therapy for the treatment of patients with metastatic melanoma. Curr. Opin. Immunol. 21(2), 233-240 (2009).
-
(2009)
Curr. Opin. Immunol.
, vol.21
, Issue.2
, pp. 233-240
-
-
Rosenberg, S.A.1
Dudley, M.E.2
-
98
-
-
0035146702
-
Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action
-
Erba E, Bergamaschi D, Bassano L et al.: Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action. Eur. J. Cancer 37(1), 97-105 (2001).
-
(2001)
Eur. J. Cancer
, vol.37
, Issue.1
, pp. 97-105
-
-
Erba, E.1
Bergamaschi, D.2
Bassano, L.3
-
99
-
-
0034813203
-
Sensitivity of soft tissue sarcoma cell lines to chemotherapeutic agents: Identification of ecteinascidin-743 as a potent cytotoxic agent
-
Li WW, Takahashi N, Jhanwar S et al.: Sensitivity of soft tissue sarcoma cell lines to chemotherapeutic agents: identification of ecteinascidin-743 as a potent cytotoxic agent. Clin. Cancer Res. 7(9), 2908-2911 (2001).
-
(2001)
Clin. Cancer Res.
, vol.7
, Issue.9
, pp. 2908-2911
-
-
Li, W.W.1
Takahashi, N.2
Jhanwar, S.3
-
100
-
-
2942571277
-
A Phase II study of ET-743/trabectedin ('Yondelis') for patients with advanced gastrointestinal stromal tumours
-
Blay JY, Le Cesne A, Verweij J et al.: A Phase II study of ET-743/trabectedin ('Yondelis') for patients with advanced gastrointestinal stromal tumours. Eur. J. Cancer 40(9), 1327-1331 (2004).
-
(2004)
Eur. J. Cancer
, vol.40
, Issue.9
, pp. 1327-1331
-
-
Blay, J.Y.1
Le Cesne, A.2
Verweij, J.3
-
101
-
-
19944426087
-
A Phase i and pharmacokinetic study of ecteinascidin-743 (Yondelis) in children with refractory solid tumors
-
A Children's Oncology Group study
-
Lau L, Supko JG, Blaney S et al.: A Phase I and pharmacokinetic study of ecteinascidin-743 (Yondelis) in children with refractory solid tumors. A Children's Oncology Group study. Clin. Cancer Res. 11(2 Pt 1), 672-677 (2005).
-
(2005)
Clin. Cancer Res.
, vol.11
, Issue.2 PART 1
, pp. 672-677
-
-
Lau, L.1
Supko, J.G.2
Blaney, S.3
-
102
-
-
54049091219
-
RANKL inhibition in the treatment of bone metastases
-
Lipton A, Jun S: RANKL inhibition in the treatment of bone metastases. Curr. Opin. Support Palliat. Care 2(3), 197-203 (2008).
-
(2008)
Curr. Opin. Support Palliat. Care
, vol.2
, Issue.3
, pp. 197-203
-
-
Lipton, A.1
Jun, S.2
-
103
-
-
33644760436
-
A study of the biological receptor activator of nuclear factor-kB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancer
-
Body JJ, Facon T, Coleman RE et al.: A study of the biological receptor activator of nuclear factor-kB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancer. Clin. Cancer Res. 12(4), 1221-1228 (2006).
-
(2006)
Clin. Cancer Res.
, vol.12
, Issue.4
, pp. 1221-1228
-
-
Body, J.J.1
Facon, T.2
Coleman, R.E.3
-
104
-
-
68949159770
-
Role of denosumab in breast cancer
-
Bartsch R, Steger GG: Role of denosumab in breast cancer. Expert Opin. Biol. Ther. 9(9), 1225-1233 (2009).
-
(2009)
Expert Opin. Biol. Ther.
, vol.9
, Issue.9
, pp. 1225-1233
-
-
Bartsch, R.1
Steger, G.G.2
-
105
-
-
70349488703
-
An open-label, Phase 2 trial of denosumab in the treatment of relapsed or plateau-phase multiple myeloma
-
Vij R, Horvath N, Spencer A et al.: An open-label, Phase 2 trial of denosumab in the treatment of relapsed or plateau-phase multiple myeloma. Am. J. Hematol. 84(10), 650-656 (2009).
-
(2009)
Am. J. Hematol.
, vol.84
, Issue.10
, pp. 650-656
-
-
Vij, R.1
Horvath, N.2
Spencer, A.3
-
106
-
-
58149198581
-
Extended efficacy and safety of denosumab in breast cancer patients with bone metastases not receiving prior bisphosphonate therapy
-
Lipton A, Steger GG, Figueroa J et al.: Extended efficacy and safety of denosumab in breast cancer patients with bone metastases not receiving prior bisphosphonate therapy. Clin. Cancer Res. 14(20), 6690-6696 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, Issue.20
, pp. 6690-6696
-
-
Lipton, A.1
Steger, G.G.2
Figueroa, J.3
-
107
-
-
63749094012
-
Randomized Phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates
-
Fizazi K, Lipton A, Mariette X et al.: Randomized Phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates. J. Clin. Oncol. 27(10), 1564-1571 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.10
, pp. 1564-1571
-
-
Fizazi, K.1
Lipton, A.2
Mariette, X.3
-
108
-
-
33847405376
-
Pazopanib: A novel multitargeted tyrosine kinase inhibitor
-
Sonpavde G, Hutson TE: Pazopanib: a novel multitargeted tyrosine kinase inhibitor. Curr. Oncol. Rep. 9(2), 115-119 (2007).
-
(2007)
Curr. Oncol. Rep.
, vol.9
, Issue.2
, pp. 115-119
-
-
Sonpavde, G.1
Hutson, T.E.2
-
109
-
-
67449164582
-
Phase i trial of pazopanib in patients with advanced cancer
-
Hurwitz HI, Dowlati A, Saini S et al.: Phase I trial of pazopanib in patients with advanced cancer. Clin. Cancer Res. 15(12), 4220-4227 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, Issue.12
, pp. 4220-4227
-
-
Hurwitz, H.I.1
Dowlati, A.2
Saini, S.3
-
110
-
-
39049095199
-
Pazopanib, a potent orally administered small-molecule multitargeted tyrosine kinase inhibitor for renal cell carcinoma
-
Sonpavde G, Hutson TE, Sternberg CN: Pazopanib, a potent orally administered small-molecule multitargeted tyrosine kinase inhibitor for renal cell carcinoma. Expert Opin. Invest. Drugs 17(2), 253-261 (2008).
-
(2008)
Expert Opin. Invest. Drugs
, vol.17
, Issue.2
, pp. 253-261
-
-
Sonpavde, G.1
Hutson, T.E.2
Sternberg, C.N.3
-
111
-
-
67650337802
-
Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: A Phase II study from the European Organisation for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC study 62043)
-
Sleijfer S, Ray-Coquard I, Papai Z et al.: Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a Phase II study from the European Organisation for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC study 62043). J. Clin. Oncol. 27(19), 3126-3132 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.19
, pp. 3126-3132
-
-
Sleijfer, S.1
Ray-Coquard, I.2
Papai, Z.3
-
112
-
-
33845882259
-
The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma
-
Podar K, Tonon G, Sattler M et al.: The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma. Proc. Natl Acad. Sci. USA 103(51), 19478-19483 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.51
, pp. 19478-19483
-
-
Podar, K.1
Tonon, G.2
Sattler, M.3
-
113
-
-
57349179851
-
Pazopanib, a VEGF receptor tyrosine kinase inhibitor for cancer therapy
-
Sloan B, Scheinfeld NS: Pazopanib, a VEGF receptor tyrosine kinase inhibitor for cancer therapy. Curr. Opin. Invest. Drugs 9(12), 1324-1335 (2008).
-
(2008)
Curr. Opin. Invest. Drugs
, vol.9
, Issue.12
, pp. 1324-1335
-
-
Sloan, B.1
Scheinfeld, N.S.2
-
114
-
-
33846212284
-
Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
-
Liu L, Cao Y, Chen C et al.: Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. Cancer Res. 66(24), 11851-11858 (2006).
-
(2006)
Cancer Res
, vol.66
, Issue.24
, pp. 11851-11858
-
-
Liu, L.1
Cao, Y.2
Chen, C.3
-
115
-
-
72449133456
-
Sorafenib induces growth inhibition and apoptosis in human synovial sarcoma cells via inhibiting the RAF/MEK/ERK signaling pathway. Cancer
-
Peng CL, Guo W, Ji T et al.: Sorafenib induces growth inhibition and apoptosis in human synovial sarcoma cells via inhibiting the RAF/MEK/ERK signaling pathway. Cancer Biol. Ther. 8(18), 1729-1736 (2009).
-
(2009)
Biol. Ther.
, vol.8
, Issue.18
, pp. 1729-1736
-
-
Peng, C.L.1
Guo, W.2
Ji, T.3
-
116
-
-
74549210540
-
Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways
-
Pignochino Y, Grignani G, Cavalloni G et al.: Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways. Mol. Cancer 8, 118 (2009).
-
(2009)
Mol. Cancer
, vol.8
, pp. 118
-
-
Pignochino, Y.1
Grignani, G.2
Cavalloni, G.3
-
117
-
-
67650293850
-
Phase II study of sorafenib in patients with metastatic or recurrent sarcomas
-
Maki RG, D'Adamo DR, Keohan ML et al.: Phase II study of sorafenib in patients with metastatic or recurrent sarcomas. J. Clin. Oncol. 27(19), 3133-3140 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.19
, pp. 3133-3140
-
-
Maki, R.G.1
D'Adamo, D.R.2
Keohan, M.L.3
-
118
-
-
39149114438
-
HDAC inhibitors: A potential new category of anti-tumor agents
-
Pan LN, Lu J, Huang B: HDAC inhibitors: a potential new category of anti-tumor agents. Cell. Mol. Immunol. 4(5), 337-343 (2007).
-
(2007)
Cell. Mol. Immunol.
, vol.4
, Issue.5
, pp. 337-343
-
-
Pan, L.N.1
Lu, J.2
Huang, B.3
-
119
-
-
23244432614
-
Antitumor effects of histone deacetylase inhibitor on Ewing's family tumors
-
Sakimura R, Tanaka K, Nakatani F et al.: Antitumor effects of histone deacetylase inhibitor on Ewing's family tumors. Int. J. Cancer 116(5), 784-792 (2005).
-
(2005)
Int. J. Cancer
, vol.116
, Issue.5
, pp. 784-792
-
-
Sakimura, R.1
Tanaka, K.2
Nakatani, F.3
-
120
-
-
19444376494
-
Significant growth suppression of synovial sarcomas by the histone deacetylase inhibitor FK228 in vitro and in vivo
-
Ito T, Ouchida M, Morimoto Y et al.: Significant growth suppression of synovial sarcomas by the histone deacetylase inhibitor FK228 in vitro and in vivo. Cancer Lett. 224(2), 311-319 (2005).
-
(2005)
Cancer Lett
, vol.224
, Issue.2
, pp. 311-319
-
-
Ito, T.1
Ouchida, M.2
Morimoto, Y.3
-
121
-
-
57749179753
-
Preclinical evaluation of the antineoplastic action of 5-aza-2́-deoxycytidine and different histone deacetylase inhibitors on human Ewing's sarcoma cells
-
Hurtubise A, Bernstein ML, Momparler RL: Preclinical evaluation of the antineoplastic action of 5-aza-2́-deoxycytidine and different histone deacetylase inhibitors on human Ewing's sarcoma cells. Cancer Cell Int. 8, 16 (2008).
-
(2008)
Cancer Cell Int
, vol.8
, pp. 16
-
-
Hurtubise, A.1
Bernstein, M.L.2
Momparler, R.L.3
-
122
-
-
45949083938
-
Suberoylanilide hydroxamic acid (SAHA) induces apoptosis or autophagy-associated cell death in chondrosarcoma cell lines
-
Yamamoto S, Tanaka K, Sakimura R et al.: Suberoylanilide hydroxamic acid (SAHA) induces apoptosis or autophagy-associated cell death in chondrosarcoma cell lines. Anticancer Res. 28(3A), 1585-1591 (2008).
-
(2008)
Anticancer Res
, vol.28
, Issue.3 A
, pp. 1585-1591
-
-
Yamamoto, S.1
Tanaka, K.2
Sakimura, R.3
-
123
-
-
33846266216
-
The effects of histone deacetylase inhibitors on the induction of differentiation in chondrosarcoma cells
-
Sakimura R, Tanaka K, Yamamoto S et al.: The effects of histone deacetylase inhibitors on the induction of differentiation in chondrosarcoma cells. Clin. Cancer Res. 13(1), 275-282 (2007).
-
(2007)
Clin. Cancer Res.
, vol.13
, Issue.1
, pp. 275-282
-
-
Sakimura, R.1
Tanaka, K.2
Yamamoto, S.3
-
124
-
-
67651205908
-
Initial testing (stage 1) of vorinostat (SAHA) by the pediatric preclinical testing program
-
Keshelava N, Houghton PJ, Morton CL et al.: Initial testing (stage 1) of vorinostat (SAHA) by the pediatric preclinical testing program. Pediatr. Blood Cancer 53(3), 505-508 (2009).
-
(2009)
Pediatr. Blood Cancer
, vol.53
, Issue.3
, pp. 505-508
-
-
Keshelava, N.1
Houghton, P.J.2
Morton, C.L.3
|