Selective apoptotic killing of solid and hematologic tumor cells by bombesin-targeted delivery of mitochondria-disrupting peptides

Molecular Pharmaceutics

Volumn 7, Issue 2, 2010, Pages 586-596

  Cai, Huawei ^a   Yang, Hao ^a   Xiang, Bin ^a   Li, Shengfu ^a   Liu, Shan ^a   Wan, Lin ^a   Zhang, Jie ^a   Li, Youping ^a   Cheng, Jingqiu ^a   Lu, Xiaofeng ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Apoptosis; Bombesin; Drug delivery system; Targeted therapy; Tumor homing peptide

Indexed keywords

BOMBESIN; CASPASE; MITOCHONDRIA DISRUPTING PEPTIDE B27; MITOCHONDRIA DISRUPTING PEPTIDE B28; MITOCHONDRIA DISRUPTING PEPTIDE BB27; MITOCHONDRIA DISRUPTING PEPTIDE BB28; MITOCHONDRIA DISRUPTING PEPTIDE KB; MITOCHONDRIA DISRUPTING PEPTIDE KLA; PEPTIDE; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD CELL; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOLID TUMOR; TUMOR CELL; TUMOR GROWTH; TUMOR XENOGRAFT;

AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BOMBESIN; CELL LINE; CELL LINE, TUMOR; CELLS, CULTURED; FEMALE; HELA CELLS; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PEPTIDES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77950591472     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp900280s     Document Type: Article

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