Novel method for concentrating and drying polymeric nanoparticles: Hydrogen bonding coacervate precipitation

Molecular Pharmaceutics

Volumn 7, Issue 2, 2010, Pages 557-564

  D'Addio, Suzanne M ^a   Kafka, Concepcion ^a   Akbulut, Mustafa ^a,c   Beattie, Patrick ^a   Saad, Walid ^a   Herrera, Margarita ^a,d   Kennedy, Michael T ^b   Prud'Homme, Robert K ^a  

^a Princeton University   (United States)

^b AMGEN INC   (United States)

^c Department of Electrical and Computer Engineering   (United States)

^d Johns Hopkins University   (United States)

Author keywords

Aggregation; Citric acid; Coacervate; Drying; Hydrogen bonding; Lyophilization; Nanoparticle; Poly(acrylic acid); Poly(aspartic acid); Polymeric nanoparticles; Redispersion

Indexed keywords

BETA CAROTENE; CITRIC ACID; CRYOPROTECTIVE AGENT; ETHYLENE OXIDE; MACROGOL; NANOPARTICLE; NEUTRALIZING ANTIBODY; POLYACRYLIC ACID; POLYASPARTIC ACID; POLYMER; SUCROSE;

ARTICLE; COACERVATION; CONTROLLED STUDY; CYTOTOXICITY; EVAPORATION; FREEZE DRYING; HUMAN; HUMAN CELL; HYDROGEN BOND; IONIZATION; PRECIPITATION; PRIORITY JOURNAL;

DESICCATION; HYDROGEN BONDING; MODELS, THEORETICAL; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYMERS;

EID: 77950563111     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp900260q     Document Type: Article

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