Modulation of aggregate size- and shape-distributions of the amyloid-β peptide by a designed β-sheet breaker

European Biophysics Journal

Volumn 39, Issue 3, 2010, Pages 415-422

  Nagel Steger, Luitgard ^a   Demeler, Borries ^b   Meyer Zaika, Wolfgang ^c   Hochdörffer, Katrin ^c   Schrader, Thomas ^c   Willbold, Dieter ^a,d  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b University of Texas Health Science Center   (United States)

^c UNIVERSITY OF DUISBURG ESSEN   (Germany)

^d FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

Aggregation inhibitor; Alzheimer's disease; Amyloid ; Peptide; Sedimentation velocity centrifugation; Thioflavin T; Transmission electron microscopy

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA-PROTEIN (1-42); CALCIUM CARBONATE; CITRIC ACID; DIMETHYL SULFOXIDE; MAGNESIUM OXIDE; PEPTIDE FRAGMENT; SUBY'S G SOLUTION; THIAZOLE DERIVATIVE; THIOFLAVINE;

ARTICLE; CHEMISTRY; COMPUTER PROGRAM; DENSITY GRADIENT CENTRIFUGATION; DRUG COMBINATION; FLUORESCENCE; MOLECULAR WEIGHT; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; SIGNAL PROCESSING; TIME; TRANSMISSION ELECTRON MICROSCOPY;

AMYLOID BETA-PROTEIN; CALCIUM CARBONATE; CENTRIFUGATION, DENSITY GRADIENT; CITRATES; DIMETHYL SULFOXIDE; DRUG COMBINATIONS; FLUORESCENCE; MAGNESIUM OXIDE; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR WEIGHT; PEPTIDE FRAGMENTS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; SIGNAL PROCESSING, COMPUTER-ASSISTED; SOFTWARE; THIAZOLES; TIME FACTORS;

EID: 77950552292     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-009-0416-2     Document Type: Conference Paper

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