Triptan exposure during pregnancy and the risk of major congenital malformations and adverse pregnancy outcomes: Results from the Norwegian mother and child cohort study

Headache

Volumn 50, Issue 4, 2010, Pages 563-575

  Nezvalová Henriksen, Kateřina ^a   Spigset, Olav ^b,c   Nordeng, Hedvig ^a,d  

^a UNIVERSITY OF OSLO   (Norway)

^b TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^c NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Adverse pregnancy outcomes; Major congenital malformations; Pregnancy; Triptans

Indexed keywords

ALMOTRIPTAN; ANGIOTENSIN II ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARBAMAZEPINE; DICLOFENAC; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ELETRIPTAN; ERGOTAMINE; FOLIC ACID; IBUPROFEN; NAPROXEN; NARATRIPTAN; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; RIZATRIPTAN; SULFAMETHOXAZOLE; SUMATRIPTAN; TETRACYCLINE DERIVATIVE; TRIMETHOPRIM; TRIPTAN DERIVATIVE; ZOLMITRIPTAN;

ACCIDENTAL INJURY; ADULT; ANEMIA; APGAR SCORE; ARTICLE; ASTHMA; BLEEDING; COHORT ANALYSIS; CONGENITAL MALFORMATION; CONTROLLED STUDY; DEMOGRAPHY; DEPRESSION; DISEASE REGISTRY; DRUG EXPOSURE; DRUG FEVER; DRUG INFORMATION; DRUG SAFETY; ECLAMPSIA; FEMALE; FIRST TRIMESTER PREGNANCY; FOLIC ACID DEFICIENCY; HOSPITALIZATION; HUMAN; HYDRAMNIOS; INFANT MORTALITY; LABOR COMPLICATION; LABOR INDUCTION; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; MATERNAL DIABETES MELLITUS; MATERNAL DISEASE; MATERNAL HYPERTENSION; MIGRAINE; MOTHER CHILD RELATION; NEWBORN; NEWBORN MORTALITY; NORWAY; OBSTETRIC HEMORRHAGE; OLIGOHYDRAMNIOS; PLACENTA PREVIA; POPULATION RESEARCH; PREECLAMPSIA; PREGNANCY; PREGNANCY OUTCOME; PREGNANT WOMAN; PREMATURITY; PRIORITY JOURNAL; PROTEINURIA; PYELONEPHRITIS; RISK FACTOR; SECOND TRIMESTER PREGNANCY; SIDE EFFECT; SOCIOECONOMICS; SOLUTIO PLACENTAE; SPONTANEOUS ABORTION; STILLBIRTH; TERATOGENESIS; THIRD TRIMESTER PREGNANCY; THYROID DISEASE; URINARY TRACT INFECTION; UTERINE ATONY; VAGINA BLEEDING; VITAMIN SUPPLEMENTATION; VOMITING;

ABNORMALITIES, DRUG-INDUCED; ADOLESCENT; ADULT; CAUSALITY; COHORT STUDIES; DRUG TOXICITY; FEMALE; HUMANS; MIGRAINE DISORDERS; NORWAY; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY TRIMESTER, FIRST; PRENATAL EXPOSURE DELAYED EFFECTS; REGISTRIES; RISK ASSESSMENT; RISK FACTORS; TRYPTAMINES; YOUNG ADULT;

EID: 77950523882     PISSN: 00178748     EISSN: 15264610     Source Type: Journal    
DOI: 10.1111/j.1526-4610.2010.01619.x     Document Type: Article

References (48)

1. Lipton RB, Stewart WF, Diamond S, Diamond ML, Reed M. Prevalence and burden of migraine in the United States: Data from the American migraine study II. Headache. 2001 41 : 646 657.
2. Sances G, Granella F, Nappi RE, et al. Course of migraine during pregnancy and postpartum: A prospective study. Cephalalgia. 2003 23 : 197 205.
3. Granella F, Sances G, Zanferrari C, Costa A, Martignoni E, Manzoni GC. Migraine without aura and reproductive life events: A clinical epidemiological study in 1300 women. Headache. 1993 33 : 385 389.
4. Maggioni F, Alessi C, Maggino T, Zanchin G. Headache during pregnancy. Cephalalgia. 1997 17 : 765 769.
5. Marcus DA, Scharff L, Turk DC. Longitudinal prospective study of headache during pregnancy and postpartum. Headache. 1999 39 : 625 632.
6. Silberstein SD, Lipton RB, Goadsby PJ. Headache in Clinical Practice, 2nd edn.
7. Nezvalová-Henriksen K, Spigset O, Nordeng H. Maternal characteristics and migraine pharmacotherapy during pregnancy: Cross sectional analysis of data from a large cohort study. Cephalalgia. 2009 29 : 1267 1276.
8. Källén B, Lygner PE. Delivery outcome in women who used drugs for migraine during pregnancy with special reference to sumatriptan. Headache. 2001 41 : 351 356.
9. Olesen C, Steffensen FH, Sørensen HT, Nielsen GL, Olsen J. Pregnancy outcome following prescription for sumatriptan. Headache. 2000 40 : 20 24.
10. O'Quinn S, Ephross SA, Williams V, Davis RL, Gutterman DL, Fox AW. Pregnancy and perinatal outcomes in migraineurs using sumatriptan: A prospective study. Arch Gynecol Obstet. 1999 263 : 7 12.
11. Shuhaiber S, Pastuszak A, Schick B, et al. Pregnancy outcome following first trimester exposure to sumatriptan. Neurology. 1998 51 : 581 583.
12. Cunnington M, Ephross S, Churchill P. The safety of sumatriptan and naratriptan in pregnancy: What have we learned? Headache. 2009 49 : 1414 1422.
13. Fiore M, Shields KE, Santanello N, Goldberg MR. Exposure to rizatriptan during pregnancy: Post-marketing experience up to 30 June 2004. Cephalalgia. 2005 25 : 685 688.
14. EUROCAT: European Surveillance of Congenital Malformations. 1980-2000 Prevalence data. Available at: http://www.eurocat.ulster.ac.uk/ (accessed March 8, 2009).
15. March of Dimes. Available at: http://www.marchofdimes.com/) (accessed March 8, 2009).
16. Castilla EE, Orioli IM. ECLAMC: The latin-American Collaborative Study of Congenital Malformations. Community Genet. 2004 7 : 76 94.
17. Facchinetti F, Allais G, Nappi RE, D'Amico R, Marozio L, Bertozzi L, Ornati A, Benedetto C. Migraine is a risk factor for hypertensive disorders in pregnancy: A prospective cohort study. Cephalalgia. 2009 29 : 286 292.
18. Chang CL, Donaghy M, Poulter N. The World Health Organization Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception. Migraine and stroke in young women: A case-control study. BMJ. 1999 318 : 13 18.
19. Facchinetti F, Allais G, D'Amico R, Benedetto C, Volpe A. The relationship between headache and preeclampsia: A case-control study. Eur J Obstet Gynecol Reprod Biol. 2004 121 : 143 148.
20. Scher AI, Terwindt GM, Picavet HSJ, Verschuren WMM, Ferrari MD, Launer LJ. Cardiovascular risk factors and migraine: The GEM population-based study. Neurology. 2005 64 : 614 620.
21. Adeney KL, Williams MA, Miller RS, Frederick IO, Sorensen TK, Luthy DA. Risk of preeclampsia in relation to maternal history of migraine headaches. J Matern Fetal Neonatal Med. 2005 18 : 167 172.
22. James AH, Bushnell CD, Jamison MG, Myers ER. Incidence and risk factors for stroke in pregnancy and the puerperium. Obstet Gynecol. 2005 106 : 509 516.
23. Norwegian Institute of Public Health. The Norwegian Mother and Child Cohort Study.
24. Norwegian Institute of Public Health. Medisinsk Fødselsregister.
25. WHO Collaborating Centre for Drug Statistics Methodology. ATC/DDD Index 2008. Available at: http://www.whocc.no/atcddd/ (accessed March 2, 2009).
26. Lipton RB, Bigal ME. Migraine: Epidemiology, impact, and risk factors for progression. Headache. 2005 45 : 3 31.
27. Rukmini M, Bushnell CD. Headache and pregnancy. Neurologist. 2008 14 : 108 119.
28. Bigal ME, Lipton RB. Modifiable risk factors for migraine progression. Headache. 2006 46 : 1334 1143.
29. Jensen R, Stovner LJ. Epidemiology and co morbidity of headache. Lancet Neurol. 2008 7 : 354 361.
30. Wacogne C, Lacoste JP, Guillibert E, Hugues FC, Le Jeune C. Stress, anxiety, depression and migraine. Cephalalgia. 2003 23 : 451 455.
31. Aamodt AH, Stovner LJ, Langhammer A, Hagen K, Zwart J-A. Is headache related to asthma, hay fever, and chronic bronchitis? The Head-HUNT study. Headache. 2007 47 : 204 212.
32. Gudmundson LS, Thorgeirsson G, Sigfusson N, Sigvaldason H, Johannsson M. Migraine patients have lower systolic but higher diastolic blood pressure compared with controls in a population-based study of 21 537 subjects. The Reykjavik Study. Cephalalgia. 2005 26 : 436 444.
33. Bigal M, Lipton B. The prognosis of migraine. Curr Opin Neurol. 2008 21 : 301 308.
34. James AH, Bushnell CD, Jamison MG, Myers ER. Incidence and risk factors for stroke in pregnancy and the puerperium. Obstet Gynecol. 2005 106 : 509 516.
35. Adeney KL, Williams MA. Migraine headaches and preeclampsia: An epidemiologic review. Headache. 2006 46 : 794 803.
36. Banhidy F, Acs N, Horvath-Puho E, Czeizel AE. Pregnancy complications and delivery outcomes in pregnant women with severe migraine. Eur J Obstet Gynecol Reprod Biol. 2007 134 : 157 163.
37. Banhidy F, Acs N, Horvath-Puho E, Czeizel AE. Maternal severe migraine and risk of congenital limb deficiencies. Birth Defects Res A Clin Mol Teratol. 2006 76 : 592 601.
38. Edwards CJ, Hughes GRV. Hughes syndrome (the antiphospholipid syndrome): 25 years old. Mod Rheumatol. 2008 18 : 119 124.
39. Panconesi A. Serotonin and migraine: A reconsideration of the central theory. J Headache Pain. 2008 9 : 267 276.
40. Cordeaux Y, Pasupathy D, Bacon J, Charnock-Jones SD, Smith GCS. Characterization of serotonin receptors in pregnant human myometrium. JPET. 2009 328 : 682 691.
41. Soldin OP, Dahlin J, O'Mara DM. Triptans in pregnancy. Ther Drug Monit. 2008 30 : 5 9.
42. Al-Zirqi I, Vangen S, Forsen L, Stray-Pedersen B. Prevalence and risk factors of severe obstetric haemorrhage. BJOG. 2008 115 : 1265 1272.
43. Llewellyn-Jones D. Fundamentals of Obstetrics and Gynaecology
44. Rossi C, Pini LA, Cupini ML, Calabresi P, Sarchielli P. Endocannabinoids in platelets of chronic migraine patients and medication-overuse headache patients: Relation with serotonin levels. Eur J Clin Pharmacol. 2008 64 : 1 8.
45. Melve KK, Lie RT, Skjaerven R, Van Der Hagen CB, Gradek GA, Jonsrud C, Braathen GJ, Irgens LM. Registration of Down syndrome in the Medical Birth Registry of Norway: Validity and time trends. Acta Obstet Gynecol Scand. 2008 87 : 824 830.
46. Kubon C, Sivertsen A, Vindenes HA, Abyholm F, Wilcox A, Lie RT. Completeness of registration of oral clefts in a medical birth registry: A population-based study. Acta Obstet Gynecol Scand. 2007 86 : 1453 1457.
47. Magnus P, Irgens LM, Haug K, Nystad W, Skjærven R, Stoltenberg C, The MoBa Study Group. Cohort profile: The Norwegian mother and child cohort study (MoBa). Int J Epidemiol. 2006 35 : 1146 1150. (Pubitemid 44605528)
48. Nilsen RM, Vollset SM, Gjessing HK, Skjærven R, Melve KK, Schreuder P, Alsaker EA, Haug K, Daltveit AK, Magnus P. Self-selection and bias in a large prospective pregnancy cohort in Norway. Paediatr Perinat Epidemiol. 2009 23 : 597 608.