Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 8, 2010, Pages 2902-2911

  Karakurt, Arzu ^a   Özalp, Meral ^a   Işik, Şamil ^b   Stables, James P ^c   Dalkara, Sevim ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

^b ONDOKUZ MAYIS UNIVERSITY   (Turkey)

^c NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

(Arylalkyl)imidazole; 2 Acetylnaphthalene; Anticonvulsant activity; Antimicrobial activity

Indexed keywords

2 (1H IMIDAZOL 1 YL) 1 (NAPHTHALEN 2 YL)ETHYL 3 METHYLBUTANOATE; AMPICILLIN; FLUCONAZOLE; IMIDAZOLE DERIVATIVE; NAFIMIDONE; NAPHTHALENE DERIVATIVE; PENTETRAZOLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC SHOCK; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; RAT; ROTAROD TEST; SEIZURE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTICONVULSANTS; CRYSTALLOGRAPHY, X-RAY; IMIDAZOLES; MOLECULAR CONFORMATION; NAPHAZOLINE; NAPHTHALENES; RATS; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP;

MUS; RATTUS;

EID: 77950520100     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.03.010     Document Type: Article

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