Reduced interleukin-12 release from stimulated monocytes in patients with sepsis after major cancer surgery

Acta Anaesthesiologica Scandinavica

Volumn 54, Issue 5, 2010, Pages 643-648

  Mokart, D ^a   Leone, M ^b,c   Sannini, A ^a   Brun, J P ^a   Turrini, O ^a   Lelong, B ^a   Houvenaeghel, G ^a   Blache, J L ^a   Mege, J L ^c   Martin, C ^b  

^a INSTITUT PAOLI CALMETTES   (France)

^b HÔPITAL NORD   (France)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 6; LIPOPOLYSACCHARIDE;

ADULT; ARTICLE; BLOOD TRANSFUSION; CANCER SURGERY; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LENGTH OF STAY; LEUKOCYTE ACTIVATION; MONOCYTE; OPERATION DURATION; POSTOPERATIVE COMPLICATION; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; SEPSIS; UPREGULATION;

CASE-CONTROL STUDIES; DIGESTIVE SYSTEM NEOPLASMS; FEMALE; GENITAL NEOPLASMS, FEMALE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MONOCYTES; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; SEPSIS; SURGICAL PROCEDURES, ELECTIVE;

EID: 77950504632     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2010.02218.x     Document Type: Article

References (25)

1. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dainhaut JF, Gerlach H, Harvey M, Marini JJ, Marshall JC, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock 2008. Intensive Care Med 2008 34 : 17 60.
2. Desborough JP. The stress response to trauma and surgery. Br J Anaesth 2000 85 : 109 17.
3. Iwagaki H, Yagi T, Urushihara N, Morimoto Y, Jikuhara A, Isozaki H, Tanaka N. Blood transfusion and postoperative plasma cytokine antagonist levels in colorectal cancer patients. Hepatogastroenterology 2001 48 : 1351 4.
4. McBride WT, Armstrong MA, McBride SJ. Immunomodulation: an important concept in modern anaesthesia. Anaesthesia 1996 51 : 465 73.
5. Robinson PN. The effects of anesthesia on malignant disease. J Lab Clin Med 1994 123 : 16 7.
6. Mokart D, Capo C, Blache JL, Delpero JR, Houvenaeghel G, Martin C, Mege JL. Early postoperative compensatory anti-inflammatory response syndrome is associated with septic complications after major surgical trauma in patients with cancer. Br J Surg 2002 89 : 1450 6.
7. Cheadle WG, Mercer-Jones M, Heinzelmann M, Polk HC Jr. Sepsis and septic complications in the surgical patient: who is at risk? Shock 1996 6 (Suppl. 1) : S6 9.
8. Wakefield CH, Carey PD, Foulds S, Monson JR, Guillou PJ. Changes in major histocompatibility complex class II expression in monocytes and T cells of patients developing infection after surgery. Br J Surg 1993 80 : 205 9.
9. Faist E, Storck M, Hultner L, Redl H, Ertel W, Walz A, Schildberg FW. Functional analysis of monocyte activity through synthesis patterns of proinflammatory cytokines and neopterin in patients in surgical intensive care. Surgery 1992 112 : 562 72.
10. Hensler T, Heidecke CD, Hecker H, Heeg K, Bartels H, Zantl N, Wagner H, Siewert JR, Holzmann B. Increased susceptibility to postoperative sepsis in patients with impaired monocyte IL-12 production. J Immunol 1998 161 : 2655 9.
11. Spolarics Z, Siddiqi M, Siegel JH, Garcia ZC, Stein DS, Denny T, Deitch EA. Depressed interleukin-12-producing activity by monocytes correlates with adverse clinical course and a shift toward Th2-type lymphocyte pattern in severely injured male trauma patients. Crit Care Med 2003 31 : 1722 9.
12. Charlson ME, Sax FL, MacKenzie CR, Braham RL, Fields SD, Douglas RG Jr. Morbidity during hospitalization: can we predict it? J Chronic Dis 1987 40 : 705 12.
13. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med 1985 25 : 818 29.
14. Bone RC, Sibbald WJ, Sprung CL. The ACCP-SCCM consensus conference on sepsis and organ failure. Chest 1992 101 : 1481 3.
15. Baj-Krzyworzeka M, Baran J, Szatanek R, Stankiewicz D, Siedlar M, Zembala M. Prevention and reversal of tumor cell-induced monocyte deactivation by cytokines, purified protein derivative (PPD), and anti-IL-10 antibody. Cancer Immun 2004 4 : 8.
16. Mytar B, Woloszyn M, Szatanek R. Tumor cell-induced deactivation of human monocytes. J Leukoc Biol 2003 74 : 1094 101.
17. Onishi H, Kuroki H, Matsumoto K, Baba E, Sasaki N, Kuga H, Tanaka M, Katano M, Morisaki T. Monocyte-derived dendritic cells that capture dead tumor cells secrete IL-12 and TNF-alpha through IL-12TNF-alphaNF-kappaB autocrine loop. Cancer Immunol Immunother 2004 53 : 1093 100.
18. Weighardt H, Heidecke CD, Westerholt A, Emmanuilidis K, Maier S, Veit M, Gerauer K, Matevossian E, Ulm K, Siewert JR, Holzmann B. Impaired monocyte IL-12 production before surgery as a predictive factor for the lethal outcome of postoperative sepsis. Ann Surg 2002 235 : 560 7.
19. Ethuin F, Delarche C, Gougerot-Pocidalo MA, Eurin B, Jacob L, Chollet-Martin S. Regulation of interleukin 12 p40 and p70 production by blood and alveolar phagocytes during severe sepsis. Lab Invest 2003 83 : 1353 60.
20. Emmanuilidis K, Weighardt H, Matevossian E, Heidecke CD, Ulm K, Bartels H, Siewert JR, Holzmann B. Differential regulation of systemic IL-18 and IL-12 release during postoperative sepsis: high serum IL-18 as an early predictive indicator of lethal outcome. Shock 2002 18 : 301 5.
21. O'Sullivan ST, Lederer JA, Horgan AF, Chin DH, Mannick JA, Rodrick ML. Major injury leads to predominance of the T helper-2 lymphocyte phenotype and diminished interleukin-12 production associated with decreased resistance to infection. Ann Surg 1995 222 : 482 90.
22. Goebel A, Kavanagh E, Lyons A, Saporoschetz IB, Soberg C, Lederer JA, Mannick JA, Rodrick ML. Injury induces deficient interleukin-12 production, but interleukin-12 therapy after injury restores resistance to infection. Ann Surg 2000 231 : 253 61.
23. Munoz C, Carlet J, Fitting C, Misset B, Blériot JP, Cavaillon JM. Dysregulation of in vitro cytokine production by monocytes during sepsis. J Clin Invest 1991 88 : 1747 54.
24. Stanilova SA, Karakolev ZT, Dimov GS, Dobreva ZG, Miteva LD, Slavov ES, Stefanov CS, Stanilov NS. High interleukin 12 and low interleukin 10 production after in vitro stimulation detected in sepsis survivors. Intensive Care Med 2005 31 : 401 7.
25. Reddy RC, Chen GH, Newstead MW, Moore T, Zeng X, Tateda K, Standiford TJ. Alveolar macrophage deactivation in murine septic peritonitis: role of interleukin 10. Infect Immun 2001 69 : 1394 401.