Presence of Porphyromonas gingivalis and plasma cell dominance in gingival tissues with periodontitis

Oral Diseases

Volumn 16, Issue 4, 2010, Pages 375-381

  Kim, Y C ^a   Ko, Y ^b   Hong, S D ^a   Kim, K Y ^a   Lee, Y H ^a   Chae, C ^a   Choi, Y ^a  

^a Seoul National University   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

Immunology; Inflammatory diseases; Periodontium

Indexed keywords

ADULT; ARTICLE; B LYMPHOCYTE; CHRONIC INFLAMMATION; CLINICAL ARTICLE; FEMALE; GINGIVA; HUMAN; HYPOTHESIS; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATORY INFILTRATE; MALE; PATHOGENESIS; PERIODONTITIS; PLASMA CELL; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RISK FACTOR; CASE CONTROL STUDY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CYTOLOGY; IMMUNOLOGY; INTRACELLULAR SPACE; ISOLATION AND PURIFICATION; MICROBIOLOGY; MIDDLE AGED; PATHOLOGY; REFERENCE VALUE; T LYMPHOCYTE SUBPOPULATION;

FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN;

ADULT; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GINGIVA; HUMANS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SPACE; MALE; MIDDLE AGED; PERIODONTITIS; PLASMA CELLS; PORPHYROMONAS GINGIVALIS; REFERENCE VALUES; T-LYMPHOCYTE SUBSETS;

EID: 77950501561     PISSN: 1354523X     EISSN: 16010825     Source Type: Journal    
DOI: 10.1111/j.1601-0825.2009.01649.x     Document Type: Article

References (28)

1. Allenspach-Petrzilka GE, Guggenheim B (1983). Bacterial invasion of the periodontium; an important factor in the pathogenesis of periodontitis? J Clin Periodontol 10 : 609 617.
2. Belkaid Y (2008). Role of Foxp3-positive regulatory T cells during infection. Eur J Immunol 38 : 918 921.
3. Berglundh T, Donati M, Zitzmann N (2007). B cells in periodontitis: friends or enemies? Periodontol 2000 45 : 51 66.
4. Cardoso CR, Garlet GP, Moreira AP, Júnior WM, Rossi MA, Silva JS (2008). Characterization of CD4 + CD25 + natural regulatory T cells in the inflammatory infiltrate of human chronic periodontitis. J Leukoc Biol 84 : 311 318.
5. Chae C (2004). Postweaning multisystemic wasting syndrome: a review of aetiology, diagnosis and pathology. Vet J 168 : 41 49.
6. Chakravorty S, Helb D, Burday M, Connell N, Alland D (2007). A detailed analysis of 16S ribosomal RNA gene segments for the diagnosis of pathogenic bacteria. J Microbiol Methods 69 : 330 339.
7. Choi C, Chae C (1999). In-situ hybridization for the detection of porcine circovirus in pigs with postweaning multisystemic wasting syndrome. J Comp Pathol 121 : 265 270.
8. Colombo AV, da Silva CM, Haffajee A, Colombo AP (2007). Identification of intracellular oral species within human crevicular epithelial cells from subjects with chronic periodontitis by fluorescence in situ hybridization. J Periodontal Res 42 : 236 243.
9. Darveau RP, Belton CM, Reife RA, Lamont RJ (1998). Local chemokine paralysis, a novel pathogenic mechanism for Porphyromonas gingivalis. Infect Immun 66 : 1660 1665.
10. Donati M, Liljenberg B, Zitzmann NU, Berglundh T (2009). B-1a cells and plasma cells in periodontitis lesions. J Periodontal Res 44 : 683 688.
11. Gemmell E, Drysdale KE, Seymour GJ (2006). Gene expression in splenic CD4 and CD8 cells from BALB/c mice immunized with Porphyromonas gingivalis. J Periodontol 77 : 622 633.
12. Hisaeda H, Maekawa Y, Iwakawa D et al (2004). Escape of malaria parasites from host immunity requires CD4 + CD25 + regulatory T cells. Nat Med 10 : 29 30.
13. Houri-Haddad Y, Wilensky A, Shapira L (2007). T-cell phenotype as a risk factor for periodontal disease. Periodontol 2000 45 : 67 75.
14. Ji S, Hyun J, Park E, Lee BL, Kim KK, Choi Y (2007a). Susceptibility of various oral bacteria to antimicrobial peptides and to phagocytosis by neutrophils. J Periodontal Res 42 : 410 419.
15. Ji S, Kim Y, Min B-Y, Han SH, Choi Y (2007b). Innate immune responses of gingival epithelial cells to nonperiodontopathic and periodontopathic bacteria. J Periodontal Res 42 : 503 510.
16. Lamont RJ, Yilmaz O (2002). In or out: the invasiveness of oral bacteria. Periodontol 2000 30 : 61 69.
17. Meyer DH, Lippmann JE, Fives-Taylor PM (1996). Invasion of epithelial cells by Actinobacillus actinomycetemcomitans: a dynamic, multistep process. Infect Immun 64 : 2988 2997.
18. Nakajima T, Ueki-Maruyama K, Oda T et al (2005). Regulatory T-cells infiltrate periodontal disease tissues. J Dent Res 84 : 639 643.
19. Nik Tavakoli N, Hambly BD, Sullivan DR, Bao S (2008). Forkhead box protein 3: essential immune regulatory role. Int J Biochem Cell Biol 40 : 2369 2373.
20. Peković DD, Fillery ED (1984). Identification of bacteria in immunopathological mechanisms of human periodontal diseases. J Periodontal Res 19 : 329 351.
21. Riviere GR, Smith KS, Tzagaroulaki E et al (1996). Periodontal status and detection frequency of bacteria at sites of periodontal health and gingivitis. J Periodontol 67 : 109 115.
22. Saglie FR, Smith CT, Newman MG et al (1986). The presence of bacteria in the oral epithelium in periodontal disease. II. Immunohistochemical identification of bacteria. J Periodontol 57 : 492 500.
23. Sanderson RD, Lalor P, Bernfield M (1989). B lymphocytes express and lose syndecan at specific stages of differentiation. Cell Regulation 1 : 27 35.
24. Socransky SS, Haffajee AD (2005). Periodontal microbial ecology. Periodontol 2000 38 : 135 187.
25. Soukka T, Pohjola J, Inki P, Happonen RP (2000). Reduction of syndecan-1 expression is associated with dysplastic oral epithelium. J Oral Pathol Med 29 : 308 313.
26. Wang M, Hajishengallis G (2008). Lipid raft-dependent uptake, signalling and intracellular fate of Porphyromonas gingivalis in mouse macrophages. Cell Microbiol 10 : 2029 2042.
27. Yamazaki K, Nakajima T, Aoyagi T, Hara K (1993). Immunohistological analysis of memory T lymphocytes and activated B lymphocytes in tissues with periodontal disease. J Periodontal Res 28 : 324 334.
28. Yilmaz O, Verbeke P, Lamont RJ, Ojcius DM (2006). Intercellular spreading of Porphyromonas gingivalis infection in primary gingival epithelial cells. Infect Immun 74 : 703 710.