Aldosterone antisecretagogue and antihypertensive actions of adrenomedullin in patients with primary aldosteronism

Hypertension Research

Volumn 33, Issue 4, 2010, Pages 374-379

  Kita, Toshihiro ^a   Tokashiki, Mariko ^a   Kitamura, Kazuo ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Adrenomedullin; Aldosterone; C reactive protein; Humans; Primary aldosteronism

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8 ISOPROSTANE; ADRENOMEDULLIN; ALDOSTERONE; AMLODIPINE; ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; C REACTIVE PROTEIN; CORTICOTROPIN; CYCLIC AMP; CYCLIC GMP; HYDROCORTISONE; INTERLEUKIN 6; NORADRENALIN; RENIN;

AGED; ALDOSTERONE BLOOD LEVEL; ALDOSTERONE RELEASE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; ATHEROSCLEROSIS; AUGMENTATION INDEX; BLOOD PRESSURE; CAROTID ARTERY; CONTROLLED STUDY; DRUG BLOOD LEVEL; ELASTICITY; FEMALE; HEART RATE; HEART VENTRICLE OVERLOAD; HEMODYNAMICS; HORMONE ACTION; HUMAN; HYPERTENSION; IMMUNE SYSTEM; INFLAMMATION; MALE; OXIDATIVE STRESS; PRIMARY HYPERALDOSTERONISM; PROTEIN EXPRESSION; PULSE WAVE; RENIN RELEASE; THERAPY EFFECT;

ADRENOMEDULLIN; AGED; ALDOSTERONE ANTAGONISTS; ANTIHYPERTENSIVE AGENTS; FEMALE; HUMANS; HYPERALDOSTERONISM; MALE; MIDDLE AGED;

EID: 77950497159     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2010.8     Document Type: Article

References (34)

1. Eto T, Kato J, Kitamura K. Regulation of production and secretion of adrenomedullin in the cardiovascular system. Regul Pept 2002; 112: 61-69.
2. Kapas S, Martínez A, Cuttitta F, Hinson JP. Local production and action of adrenome-dullin in the rat adrenal zona glomerulosa. J Endocrinol 1998; 156: 477-484. (Pubitemid 28131465)
3. Mazzocchi G, Albertin G, Andreis PG, Neri G, Malendowicz LK, Champion HC, Bahçelioglu M, Kadowitz PJ, Nussdorfer GG. Distribution, functional role, and signaling mechanism of adrenomedullin receptors in the rat adrenal gland. Peptides 1999; 20: 1479-1487.
4. Forneris M, Gottardo L, Albertin G, Malendowicz LK, Nussdorfer GG. Expression and function of adrenomedullin and its receptors in Conn's adenoma cells. Int J Mol Med 2001; 8: 675-679.
5. Jiang W, Yang JH, Pan CS, Qi YF, Pang YZ, Tang CS. Effects of adrenomedullin on cell proliferation in rat adventitia induced by aldosterone. J Hypertens 2004; 22: 1953-1961. (Pubitemid 39336678)
6. Jiang W, Yang JH, Wang SH, Pan CS, Qi YF, Zhao J, Tang CS. Effects of adrenomedullin on aldosterone-induced cell proliferation in rat cardiac fibroblasts. Biochim Biophys Acta 2004; 1690: 265-275. (Pubitemid 39423622)
7. Rahman M, Nishiyama A, Guo P, Nagai Y, Zhang GX, Fujisawa Y, Fan YY, Kimura S, Hosomi N, Omori K, Abe Y, Kohno M. Effects of adrenomedullin on cardiac oxidative stress and collagen accumulation in aldosterone-dependent malignant hypertensive rats. J Pharmacol Exp Ther 2006; 318: 1323-1329.
8. Charles CJ, Lainchbury JG, Nicholls MG, Rademaker MT, Richards AM, Troughton RW. Adrenomedullin and the renin-angiotensin-aldosterone system. Regul Pept 2003; 112: 41-49.
9. Lainchbury JG, Troughton RW, Lewis LK, Yandle TG, Richards AM, Nicholls MG. Hemodynamic, hormonal, and renal effects of short-term adrenomedullin infusion in healthy volunteers. J Clin Endocrinol Metab 2000; 85: 1016-1020.
10. Troughton RW, Levis LK, Yandle TG, Richards AM, Nicholls MG. Hemodynamic, hormone, and urinary effects of adrenomedullin infusion in essential hypertension. Hypertension 2000; 36: 588-593.
11. McGregor DO, Troughton RW, Frampton C, Lynn KL, Yandle T, Richards AM, Nicolls MG. Hypotensive and natriuretic actions of adrenomedullin in subjects with chronic renal impairment. Hypertension 2001; 37: 1279-1284.
12. Nagaya N, Satoh T, Nishikimi T, Uematsu M, Furuichi S, Sakamaki F, Oya H, Kyotani S, Nakanishi N, Goto Y, Masuda Y, Miyatake K, Kangawa K. Hemodynamic, renal, and hormonal effects of adrenomedullin infusion in patients with congestive heart failure. Circulation 2000; 101: 498-503.
13. Blankenhorn DH, Chin HP, Conover DJ, Nessim SA. Ultrasound observation on pulsation in human carotid artery lesions. Ultrasound Med Biol 1988; 14: 583-587.
14. Nishikimi T, Karasawa T, Inaba C, Ishimura K, Tadokoro K, Koshikawa S, Yoshihara F, Nagaya N, Sakio H, Kangawa K, Matsuoka H. Effects of long-term intravenous administration of adrenomedullin (AM) plus hANP therapy in acute decompensated heart failure: a pilot study. Circ J 2009; 73: 892-898.
15. Andreis PG, Tortorella C, Mazzocchi G, Nussdorfer GG. Proadrenomedullin N-terminal 20 peptide inhibits aldosterone secretion of human adrenocortical and Conn's adenoma cells: comparison with adrenomedullin effect. J Clin Endocrinol Metab 1998; 83: 253-257.
16. Troughton RW, Frampton CM, Levis LK, Yandle TG, Richards AM, Nicholls MG. Differing thresholds for modulatory effects of adrenomedullin infusion on haemody-namic and hormone responses to angiotensin II and adrenocorticotrophic hormone in healthy volunteers. Clin Sci (Lond) 2001; 101: 103-109.
17. Petrie MC, Hillier C, Morton JJ, McMurray JJV. Adrenomedullin selectively inhibits angiotensin II-induced aldosterone secretion in humans. J Hypertens 2000; 18: 61-64.
18. Kato J, Kitamura K, Kuwasako K, Tanaka M, Ishiyama Y, Shimokubo T, Ichiki Y, Nakamura S, Kangawa K, Eto T. Plasma adrenomedullin in patients with primary aldosteronism. Am J Hypertens 1995; 8: 997-1000.
19. Letizia C, De Toma G, Cerci S, Massa R, Coassin S, Subioli S, Scuro L, De Ciocchis A. Adrenomedullin levels are high in primary aldosteronism due to adenoma and decline after surgical cure. Blood Press 1998; 7: 19-23. (Pubitemid 28137522)
20. Andreis PG, Albertin G, Conconi MT, Carraro G, Malendowicz LK, Ziolkowska A, Nussdorfer GG. Evidence for an autocrine-paracrine role of adrenomedullin in the cultured rat adrenal zona glomerulosa cells. Int J Mol Med 2002; 10: 401-405.
21. Rossi GP, Conconi MT, Malendowicz LK, Nussdorfer GG. Role of the endogenous adrenomedullin system in regulating the secretion and growth of rat adrenal cortex. Hypertens Res 2003; 26 (Suppl): S85-S92.
22. Ganquly A. Atrial natriuretic peptide-induced inhibition of aldosterone secretion: a quest for mediator(s). Am J Physiol 1992; 263: E181-E194.
23. Yokota N, Bruneau BG, Kuroski de Bold ML, de Bold AJ. Atrial natriuretic factor significantly contributes to the mineralocorticoid escape phenomenon. Evidence for a guanylate cyclase-mediated pathway. J Clin Invest 1994; 94: 1938-1946. (Pubitemid 24983314)
24. Shionoiri H, Hirawa N, Takasaki I, Ishikawa Y, Oda H, Minamisawa K, Sugimoto K, Matsukawa T, Ueda S, Miyajima E. Functional atrial natriuretic peptide receptor in human adrenal tumor. J Cardiovasc Pharmacol 1989; 13 (Suppl 6): S9-S12. (Pubitemid 19238411)
25. Rocco S, Opocher G, Carpenè G, Mantero F. Atrial natriuretic peptide infusion in primary aldosteronism. Renal, hemodynamic and hormonal effects. Am J Hypertens 1990; 3: 668-673. (Pubitemid 20330610)
26. Ihara T, Ikeda U, Tate Y, Ishibashi S, Shimada K. Positive inotropic effects of adrenomedullin on rat papillary muscle. Eur J Pharmacol 2000; 390: 167-172. (Pubitemid 30122450)
27. Szokodi I, Kinnunen P, Tavi P, Weckstrom M, Toth M, Ruskoaho H. Evidence for cAMP-independent mechanisms mediating the effects of adrenomedullin, a new inotropic peptide. Circulation 1998; 97: 1062-1070. (Pubitemid 28145377)
28. Rademaker MT, Charles CJ, Espiner EA, Nicholls MG, Richards AM. Long-term adrenomedullin administration in experimental heart failure. Hypertension 2002; 40: 667-672. (Pubitemid 35278603)
29. Yang S, Zhou M, Fowler DE, Wang P. Mechanisms of the beneficial effect of adrenomedullin and adrenomedullin-binding protein-1 in sepsis: down-regulation of proinflammatory cytokines. Crit Care Med 2002; 30: 2729-2735. (Pubitemid 36870576)
30. Wong LYF, Cheung BMY, Li Y-Y, Tang F. Adrenomedullin is both proinflammatory and anti-inflammatory: its effects on gene expression and secretion of cytokines and macrophage migration inhibitory factor in NR8383 macrophage cell line. Endocrinology 2005; 146: 1321-1327. (Pubitemid 40289319)
31. Isumi Y, Minamino N, Kubo A, Nishimoto N, Yoshizaki K, Yoshioka M, Kangawa K, Matsuo H. Adrenomedullin stimulates interleukin-6 production in Swiss 3T3 cells. Biochem Biophys Res Commun 1998; 244: 325-331. (Pubitemid 28414081)
32. Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest 2003; 111: 1805-1812.
33. Suzuki Y, Horio T, Nonogi H, Hayashi T, Kitamura K, Eto T, Kangawa K, Kawano Y. Adrenomedullin as a sensitive marker for coronary and peripheral arterial complications in patients with atherosclerotic risks. Peptides 2004; 25: 1321-1326. (Pubitemid 39180064)
34. Kato J, Tsuruda T, Kita T, Kitamura K, Eto T. Adrenomedullin: a protective factor for blood vessels. Arterioscler Thromb Vasc Biol 2005; 25: 2480-2487. (Pubitemid 43732267)