-
1
-
-
0031748545
-
Glutathione-dependent bioactivation of haloalkenes
-
Anders M.W., Dekant W. Glutathione-dependent bioactivation of haloalkenes. Annu. Rev. Pharmacol. Toxicol. 1998, 38:501-537.
-
(1998)
Annu. Rev. Pharmacol. Toxicol.
, vol.38
, pp. 501-537
-
-
Anders, M.W.1
Dekant, W.2
-
2
-
-
33846859089
-
Glutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones
-
Board P.G., Anders M.W. Glutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones. Chem. Res. Toxicol. 2007, 20:149-154.
-
(2007)
Chem. Res. Toxicol.
, vol.20
, pp. 149-154
-
-
Board, P.G.1
Anders, M.W.2
-
3
-
-
77957176507
-
1,1,1,2-Tetrafluoroethane: repeat exposure inhalation toxicity study in the rat, developmental toxicity in the rabbit, and genotoxicity in vitro and in vivo
-
Collins M.A., Rusch G.M., Sato F., Hext P.M., Millischer R.-J. 1,1,1,2-Tetrafluoroethane: repeat exposure inhalation toxicity study in the rat, developmental toxicity in the rabbit, and genotoxicity in vitro and in vivo. Fundam. Appl. Toxicol. 1995, 25:271-280.
-
(1995)
Fundam. Appl. Toxicol.
, vol.25
, pp. 271-280
-
-
Collins, M.A.1
Rusch, G.M.2
Sato, F.3
Hext, P.M.4
Millischer, R.-J.5
-
4
-
-
0029008428
-
Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Role in bioactivation and detoxication mechanisms of xenobiotics
-
Commandeur J.N., Stijntjes G.J., Vermeulen N.P. Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Role in bioactivation and detoxication mechanisms of xenobiotics. Pharmacol. Rev. 1995, 47:271-330.
-
(1995)
Pharmacol. Rev.
, vol.47
, pp. 271-330
-
-
Commandeur, J.N.1
Stijntjes, G.J.2
Vermeulen, N.P.3
-
5
-
-
0023937244
-
Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-l-cysteine and S-(1,2,2-trichlorovinyl)-l-cysteine formed by cysteine conjugate beta-lyase
-
Dekant W., Berthold K., Vamvakas S., Henschler D., Anders M.W. Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-l-cysteine and S-(1,2,2-trichlorovinyl)-l-cysteine formed by cysteine conjugate beta-lyase. Chem. Res. Toxicol. 1988, 1:175-178.
-
(1988)
Chem. Res. Toxicol.
, vol.1
, pp. 175-178
-
-
Dekant, W.1
Berthold, K.2
Vamvakas, S.3
Henschler, D.4
Anders, M.W.5
-
6
-
-
34347205616
-
Determination of enzyme kinetics and glutathione conjugates of chlortetracycline and chloroacetanilides using liquid chromatography-mass spectrometry
-
Farkas M., Berry J.O., Aga D.S. Determination of enzyme kinetics and glutathione conjugates of chlortetracycline and chloroacetanilides using liquid chromatography-mass spectrometry. Analyst 2007, 132:664-671.
-
(2007)
Analyst
, vol.132
, pp. 664-671
-
-
Farkas, M.1
Berry, J.O.2
Aga, D.S.3
-
7
-
-
0026022309
-
Tissue acylation by the chlorofluorocarbon substitute 2,2-dichloro-1,1,1-trifluoroethane
-
Harris J.W., Pohl L.R., Martin J.L., Anders M.W. Tissue acylation by the chlorofluorocarbon substitute 2,2-dichloro-1,1,1-trifluoroethane. PNAS 1991, 88:1407-1410.
-
(1991)
PNAS
, vol.88
, pp. 1407-1410
-
-
Harris, J.W.1
Pohl, L.R.2
Martin, J.L.3
Anders, M.W.4
-
8
-
-
56049086723
-
Toxicogenomic assessment of the carcinogenic potential of 2,3,3,3-tetrafluoropropene
-
Honeywell, Honeywell international, Morristown
-
Toxicogenomic assessment of the carcinogenic potential of 2,3,3,3-tetrafluoropropene. Report no. 06014, Hamner Institute for Health Sciences, Research Triangle Park, NC 2007, 1-36. Honeywell, Honeywell international, Morristown.
-
(2007)
Report no. 06014, Hamner Institute for Health Sciences, Research Triangle Park, NC
, pp. 1-36
-
-
-
9
-
-
77950864548
-
An inhalation range-finding prenatal developmental toxicity study of HFO-1234yf (2,3,3,3-tetrafluoropropene) in rabbits
-
Honeywell, George Road, Ashland, OH
-
An inhalation range-finding prenatal developmental toxicity study of HFO-1234yf (2,3,3,3-tetrafluoropropene) in rabbits. Report no. WIL-447021, WIL Research Laboratories, LLC, 1407 2008, 44805-48946. Honeywell, George Road, Ashland, OH.
-
(2008)
Report no. WIL-447021, WIL Research Laboratories, LLC, 1407
, pp. 44805-48946
-
-
-
10
-
-
0022494453
-
Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isoenzyme
-
Koop D.R. Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isoenzyme. Mol. Pharmacol. 1986, 29:399-404.
-
(1986)
Mol. Pharmacol.
, vol.29
, pp. 399-404
-
-
Koop, D.R.1
-
11
-
-
0028017797
-
Role of cytochrome P450 2E1 in the metabolism of 1,1,2,3,3,3-hexafluoropropyl methyl ether
-
Köster U., Speerschneider P., Kerssebaum R., Wittmann H., Dekant W. Role of cytochrome P450 2E1 in the metabolism of 1,1,2,3,3,3-hexafluoropropyl methyl ether. Drug Metab. Dispos. 1994, 22:667-672.
-
(1994)
Drug Metab. Dispos.
, vol.22
, pp. 667-672
-
-
Köster, U.1
Speerschneider, P.2
Kerssebaum, R.3
Wittmann, H.4
Dekant, W.5
-
12
-
-
0025975205
-
Oxidation of 1,1,1,2-tetrafluoroethane in rat liver microsomes is catalyzed primarily by cytochrome P-450IIE1
-
Olson M.J., Kim S.G., Reidy C.A., Johnson J.T., Novak R.F. Oxidation of 1,1,1,2-tetrafluoroethane in rat liver microsomes is catalyzed primarily by cytochrome P-450IIE1. Drug Metab. Dispos. 1991, 19:298-303.
-
(1991)
Drug Metab. Dispos.
, vol.19
, pp. 298-303
-
-
Olson, M.J.1
Kim, S.G.2
Reidy, C.A.3
Johnson, J.T.4
Novak, R.F.5
-
13
-
-
24944544704
-
Molecular modeling, synthesis, and preliminary biological evaluation of glutathione-S-transferase inhibitors as potential therapeutic agents
-
Procopio A., Alcaro S., Cundari S., De Nino A., Ortuso F., Sacchetta P., Pennelli A., Sindona G. Molecular modeling, synthesis, and preliminary biological evaluation of glutathione-S-transferase inhibitors as potential therapeutic agents. J. Med. Chem. 2005, 48:6084-6089.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 6084-6089
-
-
Procopio, A.1
Alcaro, S.2
Cundari, S.3
De Nino, A.4
Ortuso, F.5
Sacchetta, P.6
Pennelli, A.7
Sindona, G.8
-
14
-
-
69049117105
-
Biotransformation of trans-1,1,1,3-tetrafluoropropene (HFO-1234ze)
-
Schuster P., Bertermann R., Rusch G.M., Dekant W. Biotransformation of trans-1,1,1,3-tetrafluoropropene (HFO-1234ze). Toxicol. Appl. Pharmacol. 2009, 239:215-223.
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.239
, pp. 215-223
-
-
Schuster, P.1
Bertermann, R.2
Rusch, G.M.3
Dekant, W.4
-
15
-
-
56049104200
-
Biotransformation of 2,3,3,3-tetrafluoropropene (HFO-1234yf)
-
Schuster P., Bertermann R., Snow T.A., Han X., Rusch G.M., Jepson G.W., Dekant W. Biotransformation of 2,3,3,3-tetrafluoropropene (HFO-1234yf). Toxicol. Appl. Pharmacol. 2008, 233:323-332.
-
(2008)
Toxicol. Appl. Pharmacol.
, vol.233
, pp. 323-332
-
-
Schuster, P.1
Bertermann, R.2
Snow, T.A.3
Han, X.4
Rusch, G.M.5
Jepson, G.W.6
Dekant, W.7
-
16
-
-
0002960833
-
Preparation of microsomes and submicrosomal fractions: mammalian
-
Siekevitz P. Preparation of microsomes and submicrosomal fractions: mammalian. Methods Enzymol. 1962, 5:61-68.
-
(1962)
Methods Enzymol.
, vol.5
, pp. 61-68
-
-
Siekevitz, P.1
-
18
-
-
0026645046
-
Dominant role of cytochrome P-450 2E1 in human hepatic microsomal oxidation of the CFC-substitute 1,1,1,2-tetrafluoroethane
-
Surbrook S.E.J., Olson M.J. Dominant role of cytochrome P-450 2E1 in human hepatic microsomal oxidation of the CFC-substitute 1,1,1,2-tetrafluoroethane. Drug Metab. Dispos. 1992, 20:518-524.
-
(1992)
Drug Metab. Dispos.
, vol.20
, pp. 518-524
-
-
Surbrook, S.E.J.1
Olson, M.J.2
-
19
-
-
77950861267
-
-
TNO Bacterial Reverse Mutation Test with HFO-1234yf. TNO Study 6202/09, TNO Quality of Life, Zeist, The Netherlands conducted for Honeywell International, ref. MA-RR-07-3198. (17. April. 2007).
-
TNO (2007). Bacterial Reverse Mutation Test with HFO-1234yf. TNO Study 6202/09, TNO Quality of Life, Zeist, The Netherlands conducted for Honeywell International, ref. MA-RR-07-3198. (17. April. 2007).
-
(2007)
-
-
-
20
-
-
0028258364
-
Metabolism of the chlorofluorocarbon substitute 1,1-dichloro-2,2,2-trifluoroethane by rat and human liver microsomes: the role of cytochrome P450 2E1
-
Urban G., Speerschneider P., Dekant W. Metabolism of the chlorofluorocarbon substitute 1,1-dichloro-2,2,2-trifluoroethane by rat and human liver microsomes: the role of cytochrome P450 2E1. Chem. Res. Toxicol. 1994, 7:170-176.
-
(1994)
Chem. Res. Toxicol.
, vol.7
, pp. 170-176
-
-
Urban, G.1
Speerschneider, P.2
Dekant, W.3
-
21
-
-
0024470691
-
Cytotoxicity of cysteine S-conjugates: structure-activity relationships
-
Vamvakas S., Kochling A., Berthold K., Dekant W. Cytotoxicity of cysteine S-conjugates: structure-activity relationships. Chem. Biol. Interact. 1989, 71:79-90.
-
(1989)
Chem. Biol. Interact.
, vol.71
, pp. 79-90
-
-
Vamvakas, S.1
Kochling, A.2
Berthold, K.3
Dekant, W.4
-
22
-
-
0029096376
-
The role of cytochrome P4503A1/2 in the sex-specific sulfoxidation of the hexachlorobutadiene metabolite, N-acetyl-S-(pentachlorobutadienyl)-l-cysteine in rats
-
Werner M., Birner G., Dekant W. The role of cytochrome P4503A1/2 in the sex-specific sulfoxidation of the hexachlorobutadiene metabolite, N-acetyl-S-(pentachlorobutadienyl)-l-cysteine in rats. Drug Metab. Dispos. 1995, 23:861-868.
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 861-868
-
-
Werner, M.1
Birner, G.2
Dekant, W.3
|