New design platform for malonyl-CoA-acyl carrier protein transacylase

FEBS Letters

Volumn 584, Issue 6, 2010, Pages 1240-1244

  Hong, Seung Kon ^a   Kim, Kook Han ^a   Park, Joon Kyu ^a   Jeong, Ki Woong ^b   Kim, Yangmee ^b   Kim, Eunice EunKyeong ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Konkuk University   (South Korea)

Author keywords

Antibacterial; FabD; Fatty acid biosynthesis; MCAT; Structure based drug design

Indexed keywords

ACYLTRANSFERASE; GLUTAMINE; GLYCINE; HISTIDINE; MALONYL COENZYME A ACYL CARRIER PROTEIN TRANSACYLASE; SERINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PURIFICATION; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

ACYL-CARRIER PROTEIN S-MALONYLTRANSFERASE; AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; ENZYME ASSAYS; ENZYME INHIBITORS; ESCHERICHIA COLI; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MYCOBACTERIUM TUBERCULOSIS; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

EID: 77950368619     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.02.038     Document Type: Article

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