Development and validation of an EI-GC-MS method for the determination of benzodiazepine drugs and their metabolites in blood: Applications in clinical and forensic toxicology

Journal of Pharmaceutical and Biomedical Analysis

Volumn 52, Issue 4, 2010, Pages 609-614

  Papoutsis, Ioannis I ^a   Athanaselis, Sotirios A ^a   Nikolaou, Panagiota D ^a   Pistos, Constantinos M ^a   Spiliopoulou, Chara A ^a   Maravelias, Constantinos P ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Benzodiazepines; Blood; GC MS

Indexed keywords

7 AMINOFLUNITRAZEPAM; ACID ANHYDRIDE; ALPRAZOLAM; BENZODIAZEPINE DERIVATIVE; BROMAZEPAM; CAMAZEPAM; CHLORDIAZEPOXIDE; CHLOROFORM; CLOBAZAM; CLONAZEPAM; DIAZEPAM; DRUG METABOLITE; FLUDIAZEPAM; FLUNITRAZEPAM; FLURAZEPAM; LORAZEPAM; LORMETAZEPAM; MEDAZEPAM; MIDAZOLAM; NIMETAZEPAM; NITRAZEPAM; NORDAZEPAM; OXAZEPAM; PRAZEPAM; TEMAZEPAM; TETRAMETHYLAMMONIUM HYDROXIDE; TETRAZEPAM; TRIAZOLAM; TRIETHYLAMINE; UNINDEXED DRUG;

ACCURACY; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG BLOOD LEVEL; DRUG DEPENDENCE; DRUG DETERMINATION; FEMALE; FORENSIC TOXICOLOGY; GAS CHROMATOGRAPHY; HUMAN; LIQUID LIQUID EXTRACTION; MALE; MASS SPECTROMETRY; PH MEASUREMENT; PRIORITY JOURNAL; PROCESS OPTIMIZATION; TRAFFIC ACCIDENT; VALIDATION STUDY; BLOOD; CASE REPORT; COMPARATIVE STUDY; ELECTROSPRAY MASS SPECTROMETRY; MASS FRAGMENTOGRAPHY; METABOLISM; MIDDLE AGED; PROCEDURES; REPRODUCIBILITY; STANDARDS;

ADULT; AGED; BENZODIAZEPINES; FEMALE; FORENSIC TOXICOLOGY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 77950368592     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.01.027     Document Type: Article

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