Selectively preparative purification of aristolochic acids and aristololactams from Aristolochia plants

Journal of Pharmaceutical and Biomedical Analysis

Volumn 52, Issue 4, 2010, Pages 446-451

  Zhang, Jing ^a   Xiao, Yuansheng ^a   Feng, Jiatao ^a   Wu, Sophia L ^b   Xue, Xingya ^a   Zhang, Xiuli ^a   Liang, Xinmiao ^a  

^a DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^b Germantown Academy   (United States)

Author keywords

Aristolochic acids; Aristololactams; Auto purification Factory; Oligo (ethylene glycol); Preparative HPLC

Indexed keywords

ACETIC ACID ETHYL ESTER; ARISTOLOCHIA EXTRACT; ARISTOLOCHIC ACID; ARISTOLOLACTAM; BUTANOL; MACROGOL; PLANT EXTRACT; UNCLASSIFIED DRUG; ARISTOLOLACTAM-I; HERBACEOUS AGENT;

ARISTOLOCHIA; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; EXTRACTION; FRUIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; PLANT ROOT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PURIFICATION; TIME OF FLIGHT MASS SPECTROMETRY; CHEMISTRY; COMPARATIVE STUDY; ISOLATION AND PURIFICATION;

ARISTOLOCHIA; ARISTOLOCHIC ACIDS; DRUGS, CHINESE HERBAL; PLANT ROOTS;

EID: 77950368494     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.01.023     Document Type: Article

References (23)

1. Zhang C.Y., Wang X., Shang M.Y., Yu J., Xu Y.Q., Li Z.G., Lei L.C., Li X.M., Cai S.Q., Namba T. Simultaneous determination of five aristolochic acids and two aristololactams in Aristolochia plants by high-performance liquid chromatography. Biomed. Chromatogr. 2006, 20:309-318.
2. Shana S.J., Norman W.S., Cristina L.Q. Assessment of Chinese medicinal herb metabolite profiles by UPLC-MS-based methodology for the detection of aristolochic acids. J. Sep. Sci. 2007, 30:1200-1206.
3. Lee M.C., Ysao C.H., Lou S.C., Chuang W.C., Sheu S.J. Analysis of aristolochic acids in herbal medicines by LC/UV and LC/MS. J. Sep. Sci. 2003, 26:818-822.
4. Wei F., Cheng X.L., Ma L.Y., Jin W.T., Schaneberg B.T., Khan I.A., Lin R.C. Analysis of aristolochic acids and analogues in medicinal plants and their commercial products by HPLC-PAD-ESI/MS. Phytochem. Anal. 2005, 16:222-230.
5. Peter H.J., Muzaffer O. Aristolochic acids and aristolactams from Aristolochia auricularis. Phytochemistry 1991, 30:519-529.
6. Li H., Sakagami Y., Marumos S., Chen X.M. Eleven aristolochic acids derivatives from Aristolochia cinnabarina. Phytochemistry 1994, 37:237-239.
7. Wu T.S., Ou L.F., Teng C.M. Aristolochic acids, aristolactam alkaloids and amides from Aristolochia kankauensis. Phytochemistry 1994, 36:1063-1068.
8. Houghtom P.J., Ogutveren M. Alkaloids and lignan from Aristolochia ponticum. Phytochemistry 1991, 30:717-718.
9. Isabele R.N., Lucia M.X.L. Diterpene esters of aristolochic acids from Aristolochia pubescens. Phytochemistry 2003, 63:953-957.
10. Wang Y.P., Xue X.Y., Xiao Y.S., Zhang F.F., Xu Q., Liang X.M. Purification and preparation of compounds from an extract of Scutellaria barbata D. Don using preparative parallel high performance liquid chromatography. J. Sep. Sci. 2008, 31:1669-1676.
11. Guo Z.M., Liu Y.F., Xu J.Y., Xu Q., Xue X.Y., Zhang F.F., Ke Y.X., Ling X.M., Lei A.W. Novel reversed-phase high-performance liquid chromatography stationary phase with oligo(ethylene glycol) " click" to silica. J. Chromatogr. A 2008, 1191:78-82.
12. Wu J.H., Chang C., Qiao M. Detection on contents of aristolochic acid A in Daochi powder and its combination group with high performance liquid chromatography. Hubei Zhongyi Xueyuan Xuebao 2009, 11:30-31.
13. Ding L.S., Lou F.C., Cao M.C. Studies on the chemical constituents of Aristolochia Manishuriensis kom. Chung Tsao Yao 1986, 17:347-349.
14. Liu Y.M., Guo Z.M., Jin Y., Xue X.Y., Xu Q., Zhang F.F., Liang X.M. " Click oligo(ethylene glycol)": an excellent orthogonal stationary phase to C18 for two-dimensional reversed-phase/reversed-phase liquid chromatography. J. Chromatogr. A 2008, 1206:153-159.
15. 13C NMR spectroscopy of aristolochis acids and aristololactams. Magn. Reson. Chem. 1989, 27:460-469.
16. Zhang C.Y., Wang X., Su T., Ma C.M., Wen Y.J., Shang M.Y., Li X.M., Liu G.X., Cai S.Q. New aristolochic acid, aristololactam and renal cytotoxic constituents from the stem and leaves of Aristolochia contorta. Pharmazie 2005, 60:785-788.
17. Chen M.L., Luan J.L. A study of the chemical constituents of Wu jincao. Yi Yao Dao Bao 2005, 24:270-272.
18. Zhang S.X., Tani T., Yamaji S., Gao X.L., Wang X., Cai S.Q., Zhao Y.Y. Studies on chemical constituents from radix and rhizome of Asarum longerhizom atosum. Zhong Cao Yao 2002, 33:297-299.
19. Horacio A.P. Seven aristololactams from Aristolochia argentina. Phytochemistry 1985, 24:849-852.
20. Lou F.C., Peng G.P., Wang Y., Zhao S.X. Chemical studies on Aristolochia manshuriensis. Acta Pharm. Sin. 1995, 30:588-593.
21. Chen Y.G., Yu L.L. Studies on the chemical constituents of Aristolochia contorta. Yun Nan Shi Fan Da Xue Xue Bao 2005, 25:41-44.
22. Achari B., Bandyopadhyay S., Chakravarty A.K., Pakrashi S.C. Carbon-13 NMR spectra of some phenanthrene derivatives from Aristolochia indica and their analogues. Org. Magn. Reson. 1984, 22:741-746.
23. Wu T.S., Chan Y.Y., Leu Y.L. The constituents of the root and stem of Aristolochia cucurbitifolia hayata and their biological activity. Chem. Pharm. Bull. 2000, 48:1006-1009.