Analysis of aristolochic acids and analogues in medicinal plants and their commercial products by HPLC-PAD-ESI/MS

Phytochemical Analysis

Volumn 16, Issue 3, 2005, Pages 222-230

  Wei, Feng ^a   Cheng, Xian Long ^a   Ma, Lin Yun ^a   Jin, Wen Tao ^b   Schaneberg, Brian T ^b   Khan, Ikhlas A ^b   Lin, Rui Chao ^a  

^a NATIONAL INSTITUTE FOR THE CONTROL OF PHARMACEUTICAL AND BIOLOGICAL PRODUCTS   (China)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Akebia; Aristolochia; Aristolochic acids; Asarum; Clematis; ESI; HPLC UV MS; Stephania

Indexed keywords

AKEBIA; ARISTOLOCHIA; ARISTOLOCHIC ACID; ASARUM; CLEMATI; COMMERCIAL PRODUCTS; ESI; HPLC-UV/MS; MEDICINAL PLANTS; STEPHANIA;

ELECTROSPRAY IONIZATION;

AKEBIA QUINATA EXTRACT; AKEBIA TRIFOLATA EXTRACT; ARISTOLACHIA CONTORTA EXTRACT; ARISTOLOCHIA FANGCHI EXTRACT; ARISTOLOCHIA MANSHURIENSIS EXTRACT; ARISTOLOCHIC ACID; ASARUM HETEROTROPOIDES EXTRACT; CLEMATIS ARMANDII EXTRACT; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; STEPHANIA TETRANDRA EXTRACT; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DIODE; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION MONITORING; MEDICINAL PLANT; NONHUMAN; TOXIN ANALYSIS; ULTRAVIOLET SPECTROSCOPY;

AKEBIA; ARISTOLOCHIA; ASARUM; CLEMATIS; STEPHANIA;

EID: 21344442192     PISSN: 09580344     EISSN: None     Source Type: Journal    
DOI: 10.1002/pca.849     Document Type: Article

References (25)

1. Arlt VM, Marie Stiborova M, Schmeiser HH. 2002. Aristolochic acid as a probable human cancer hazard in herbal remedies: a review. Mutagenesis 17: 265-27.
2. Chen H, Jin R, Xu L. 1994. Determination of aristolochic acid I and total alkaloids in Fangji. Zhongguo Zhongyao Zazhi 19: 323-324.
3. Cosyns J-P. 2003. Aristolochic acid and 'Chinese Herbs Nephropathy': a review of the evidence to date. Drug Safety 26: 33-48.
4. Damu AG, Kuo P-C, Leu Y-L, Chan Y-Y, Wu T-S. 2003. Chemical constituents and pharmacology of the Formosan Aristolochia species. Chin Pharm J 55: 1-33.
5. Hashimoto K, Higuchi M, Makino B, Sakakibara I, Kubo M, Komatsu Y, Maruno M, Okada M. 1999. Quantitative analysis of aristolochic acids, toxic compounds contained in some medicinal plants. J Ethnopharmacol 64: 185-189.
6. Huang ZY, Zhao XC. 2003. Toxicity of Aristolochia plants. Lishizhen Med Materia Med Res 14: 248-249.
7. Ioset JR, Raoelison GE, Hostettmann K. 2003. Detection of aristolochic acid in Chinese phytomedicines and dietary supplements used as slimming regimens. Food Chem Toxicol 41: 29-36.
8. Jong T-T, Lee M-R, Hsiao S-S, Hsai J-L, Wu T-S, Chiang S-T, Cai S-Q. 2003. Analysis of aristolochic acid in nine sources of Xixin, a traditional Chinese medicine, by liquid chromatography/ atmospheric pressure chemical ionization/ tandem mass spectrometry. J Pharm Biomed Anal 33: 831-837.
9. Jou J-H, Chen S, Wu T-S. 2003. Facile reversed-phase HPLC resolution and quantitative determination of aristolochic acid and aristolactam analogues in traditional Chinese medicine. J Liq Chromatogr Relat Technol 26: 3057-3068.
10. Kery A, Askari AA, Sharefi KA. 1981. Quantitative TLC determination of aristolochic acid in Aristolochia maurorum. Fitoterapia 52: 201-207.
11. Kite GC, Yule MA, Leon C, Simmonds MS. 2002. Detecting aristolochic acids in herbal remedies by liquid chromatography/ serial mass spectrometry. Rapid Commun Mass Spectrom 16: 585-590.
12. Lee T-Y, Wu M-L, Deng J-F, Hwang D-F. 2002. High-performance liquid chromatographic determination for aristolochic acid in medicinal plants and slimming products. J Chromatogr B 766: 169-174.
13. Nakamura Y, Yomura K, Kikuchi Y, Ishimatsu M, Niitsu K, Sakakibara I, Higuchi M, Amagaya S, Aburada M, Okada M, Sekita S, Satake M. 2003. Quality evaluation of natural compound isolated from crude drugs (Part 2) Aristolochic acid II. Iyakuhin Kenkyu 34: 485-492.
14. Nortier JL, Muniz Martinez M-C, Schmeiser HH. 2000. Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi). New Engl J Med 342: 1686-1692.
15. Pharmacopoeia of the People's Republic of China. 2000. Chemical Industry Publishing House, Beijing.
16. Schaneberg BT, Applequist WL, Khan IA. 2002. Determination of aristolochic acid I and II in north American species of Asarum and Aristolochia. Pharmazie 10: 686-689.
17. Singh DV, Singh BL, Verma RK, Gupta MM, Banerji S, Kumar S. 2001. Quantitation of aristolochic acid using high performance liquid chromatography with photo-diode array detection. J Ind Chem Soc 78: 487-488.
18. UK Government. 2001. Statutory Instrument no. 1841. The Medicines (Aristolochia and Mu tong etc.) (prohibitions) order 2001. The Stationery Office: London.
19. US Food and Drug Administration. 2000. Dietary supplements: aristolochic acid. www.cfsan.fda.gov/dms/ds-bot.html (accessed 26 August 2002).
20. US Food and Drug Administration. 2001a. Listing of botanical ingredients of concern. Attachment A-Botanicals known or suspected to contain aristolochic acid. www.cfsan.fda.gov/-dms/ds-bot2.html (accessed 26 August 2002).
21. US Food and Drug Administration. 2001b. Listing of botanical ingredients of concern. Attachment D - Botanical products determined by FDA to contain aristolochic acids. www.cfsan.fda.gov/-dms/ds-bot2.html (accessed 26 August 2002).
22. Vanherweghem IL, Depierreux M, Tielemans C, Abramowicz D, Dratwa M, Ladoul M, Richard C, Vandervelde D, Verbeelen D, Vanhaelen-Fastre R. 1993. Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs. Lancet 341: 387-391.
23. Wang ZM. 2002. Preparations of traditional Chinese medicine containing aristolochic acids in Chinese market. China J Chin Materia Med 27: 800-801.
24. Wang, Y, Pan ZX., Jia ZZ. 2000. The research progress of genus Aristolochia. Nat Prod Res Dev 12: 84-93.
25. Zhu M, Phillipson JD. 1996. Hong Kong samples of the traditional Chinese medicine Fang ji contain aristolochic acid toxins. Int J Pharmacogn 34: 283-289.