The effect of age, menopausal state, and breast density on 18F-FDG uptake in normal glandular breast tissue

Journal of Nuclear Medicine

Volumn 51, Issue 3, 2010, Pages 347-352

  Mavi, Ayse ^a   Cermik, Tevfik F ^a   Urhan, Muammer ^a   Puskulcu, Halis ^b   Basu, Sandip ^a   Cucchiara, Andrew J ^c   Yu, Jian Q ^a   Alavi, Abass ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b IZMIR INSTITUTE OF TECHNOLOGY   (Turkey)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

18F FDG PET; Age; Breast density; Menopausal state; Normal breast

Indexed keywords

FLUORODEOXYGLUCOSE F 18; DIAGNOSTIC AGENT;

ADULT; AGE; AGED; ARTICLE; BREAST; BREAST CANCER; DRUG UPTAKE; HUMAN; MAJOR CLINICAL STUDY; MENOPAUSE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; AGING; ANALYSIS OF VARIANCE; BREAST TUMOR; CLINICAL TRIAL; CYTOLOGY; FEMALE; MAMMOGRAPHY; METABOLISM; MIDDLE AGED; PATHOLOGY; RADIOGRAPHY; SCINTISCANNING; STATISTICAL MODEL; TRANSPORT AT THE CELLULAR LEVEL;

ADULT; AGED; AGING; ANALYSIS OF VARIANCE; BIOLOGICAL TRANSPORT; BREAST; BREAST NEOPLASMS; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; LINEAR MODELS; MAMMOGRAPHY; MENOPAUSE; MIDDLE AGED;

EID: 77950364750     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.109.068718     Document Type: Article

References (37)

1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin. 2008;58:71-96.
2. Carney PA, Miglioretti DL, Yankaskas BC, et al. Individual and combined effects of age, breast density, and hormone replacement therapy use on the accuracy of screening mammography. Ann Intern Med. 2003;138:168-175.
3. Rosenberg RD, Hunt WC, Williamson MR, et al. Effects of age, breast density, ethnicity, and estrogen replacement therapy on screening mammographic sensitivity and cancer stage at diagnosis: review of 183,134 screening mammograms in Albuquerque, New Mexico. Radiology. 1998;209:511-518.
4. Baines CJ, Miller AB, Wall C, et al. Sensitivity and specificity of first screen mammography in the Canadian National Breast Screening Study: a preliminary report from five centers. Radiology. 1986;160:295-298. (Pubitemid 16070629)
5. Fletcher SW, Black W, Harris R, et al. Report of the International Workshop on Screening for Breast Cancer. J Natl Cancer Inst. 1993;85:1644-1656. (Pubitemid 23315423)
6. Frisell J, Klund G, Hellstrom L. Randomized study of mammography screening: preliminary report on mortality in the Stockholm trial. Breast Cancer Res Treat. 1991;18:49-56.
7. Kolb TM, Lichy J, Newhouse JH. Comparison of the performance of screening mammography, physical examination, and breast US and evaluation of factors that influence them: an analysis of 27,825 patient evaluations. Radiology. 2002;225:165-175.
8. Mandelson MT, Oestreicher N, Porter PL, et al. Breast density as a predictor of mammographic detection: comparison of interval- and screen-detected cancers. J Natl Cancer Inst. 2000;92:1081-1087. (Pubitemid 30616482)
9. Lehman CD, White E, Peacock S, et al. Effect of age and breast density on screening mammograms with false-positive findings. AJR. 1999;173:1651-1655.
10. Foxcroft LM, Evans EB, Joshua HK, et al. Breast cancers invisible on mammography. Aust N Z J Surg. 2000;70:162-167.
11. Wolfe JN. Breast patterns as an index of risk for developing breast cancer. AJR. 1976;126:1130-1137.
12. Warner E, Lockwood G, Tritchler D, et al. The risk of breast cancer associated with mammographic parenchymal patterns: a meta-analysis of the published literature to examine the effect of method of classification. Cancer Detect Prev. 1992;16:67-72.
13. Byrne C, Schairer C, Wolfe J, et al. Mammographic features and breast cancer risk: effectswith time, age, andmenopause status. J Natl Cancer Inst. 1995;87:1622-1629.
14. McCormack VA, dos Santos Silva I. Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysis. Cancer Epidemiol Biomarkers Prev. 2006;15:1159-1169.
15. Orel SG, Schnall MD. MR imaging of the breast for the detection, diagnosis, and staging of breast cancer. Radiology. 2001;220:13-30. (Pubitemid 32577955)
16. Liberman M, Sampalis F, Mulder DS, et al. Breast cancer diagnosis by scintimammography: a meta-analysis and review of the literature. Breast Cancer Res Treat. 2003;80:115-126. (Pubitemid 36851291)
17. Avril N, Dose J, Janicke F, et al. Metabolic characterization of breast tumors with positron emission tomography using F-18 fluorodeoxyglucose. J Clin Oncol. 1996;14:1848-1857. (Pubitemid 26185460)
18. Wahl RL, Cody RL, Hutchins GD, et al. Primary and metastatic breast carcinoma: initial clinical evaluation with PET with the radiolabeled glucose analogue 2-[F-18]-fluoro-2-deoxy-D-glucose. Radiology. 1991;179:765-770.
19. Nieweg OE, Kim EE, Wong WH. Positron emission tomography with fluorine-18-deoxyglucose in the detection and staging of breast cancer. Cancer. 1993;71:3920-3925. (Pubitemid 23172970)
20. Hoh CK, Schiepers C. 18-FDG imaging in breast cancer. Semin Nucl Med. 1999;29:49-56.
21. Mavi A, Urhan M, Yu JQ, et al. Dual time point 18F-FDG PET imaging detects breast cancer with high sensitivity and correlates well with histologic subtypes. J Nucl Med. 2006;47:1440-1446. (Pubitemid 47544929)
22. Cermik TF, Mavi A, Basu S, et al. Impact of FDG PET on the preoperative staging of newly diagnosed breast cancer. Eur J Nucl Med Mol Imaging. 2008;35:475-483. (Pubitemid 351661670)
23. Stomper PC, D'Souza DJ, DiNitto PA, et al. Analysis of parenchymal density on mammograms in 1353 women 25-79 years old. AJR. 1996;167:1261-1265.
24. Kopans DB. Bias in the medical journals: a commentary. AJR. 2005;185:176-177.
25. Bedigian MP, Benard F, Smith RJ, et al. Whole-body positron emission tomography for oncology using singles transmission scanning with segmentation and ordered subsets expectation maximization (OS-EM) reconstruction. Eur J Nucl Med. 1998;25:659-661. (Pubitemid 28297841)
26. Abramson R, Mavi A, Cermik TF, et al. Age-related structural and functional changes in the breast: multimodality correlation with digital mammography, computed tomography, magnetic resonance imaging, and positron emission tomography. Semin Nucl Med. 2007;37:146-153. (Pubitemid 46517467)
27. 18F-FDG uptake and breast density in women with normal breast tissue. J Nucl Med. 2003;44:1238-1242.
28. Kumar R, Chauhan A, Zhuang H, et al. Standardized uptake values of normal breast tissue with 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography: variations with age, breast density, and menopausal status. Mol Imaging Biol. 2006;8:355-362. (Pubitemid 44741373)
29. Mavi A, Urhan M, Yu JQ, et al. Fluorine-18 fluorodeoxyglucose uptake in normal breast: effect of breast density, menopausal status and age [abstract]. J Nucl Med. 2005;46(suppl 2):441P.
30. Mavi A, Urhan M, Zhuang H, et al. The effect of age, density and menopausal status on FDG uptake in normal breast glandular tissue [abstract]. Eur J Nucl Med Mol Imaging. 2005;32(suppl 1):158P.
31. Ciatto S, Zappa M. A prospective study of the value of mammographic patterns as indicators of breast cancer risk in a screening experience. Eur J Radiol. 1993;17:122-125. (Pubitemid 23303606)
32. Flook D, Gilhome RW, Harman J, et al. Changes in Wolfe mammographic patterns with aging. Br J Radiol. 1987;60:455-456. (Pubitemid 17065584)
33. Wolfe JN. Breast parenchymal patterns and their changes with age. Radiology. 1976;121:545-552.
34. Kerlikowske K, Grady D, Barclay J, et al. Effect of age, breast density, and family history on the sensitivity of first screening mammography. JAMA. 1996;276:33-38. (Pubitemid 26231053)
35. Mavi A, Cermik TF, Urhan M, et al. The effect of breast density on FDG uptake and its change over time in normal breast tissue [abstract]. J Nucl Med. 2006;47(suppl 1):436P.
36. Greendale GA, Reboussin BA, Slone S, et al. Post-menopausal hormone therapy and change in mammographic density. J Natl Cancer Inst. 2003;95:30-37. (Pubitemid 36124293)
37. Laya MB, Gallagher JC, Schreiman JS, et al. Effect of post-menopausal hormonal replacement therapy on mammographic density and parenchymal pattern. Radiology. 1995;196:433-437.