Glutathione-S-transferase genotypes influence the risk of chemotherapy-related toxicities and prognosis in Korean patients with diffuse large B-cell lymphoma

Cancer Genetics and Cytogenetics

Volumn 198, Issue 1, 2010, Pages 40-46

  Cho, Hyun Jung ^a   Eom, Hyeon Seok ^b   Kim, Hyun Ju ^b   Kim, In Suk ^c   Lee, Gyeong Won ^c   Kong, Sun Young ^b  

^a Konyang University College of Medicine   (South Korea)

^b National Cancer Center   (South Korea)

^c Gyeongsang National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; ISOLEUCINE; PREDNISOLONE; RITUXIMAB; VALINE; VINCRISTINE; ANTINEOPLASTIC AGENT; CHOP PROTOCOL; GLUTATHIONE S-TRANSFERASE M1; GLUTATHIONE S-TRANSFERASE T1; MONOCLONAL ANTIBODY; PREDNISONE;

ADOLESCENT; ADULT; AGED; ALOPECIA; ANEMIA; ARTICLE; BLOOD TOXICITY; CANCER SURVIVAL; CLINICAL EVALUATION; CONTROLLED STUDY; DIARRHEA; EVENT FREE SURVIVAL; FEMALE; FEVER; GENE DELETION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC DIFFERENCE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; INFECTION; KOREA; LARGE CELL LYMPHOMA; LEUKOPENIA; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; MULTIPLEX POLYMERASE CHAIN REACTION; NAUSEA; NEUROTOXICITY; NEUTROPENIA; NULL ALLELE; PRIORITY JOURNAL; PROGNOSIS; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; THERAPY EFFECT; THROMBOCYTOPENIA; TREATMENT RESPONSE; VOMITING; ASIAN; GENETICS; MIDDLE AGED; MORTALITY; RISK; TREATMENT OUTCOME;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ASIAN CONTINENTAL ANCESTRY GROUP; CYCLOPHOSPHAMIDE; DOXORUBICIN; FEMALE; GENE DELETION; GENOTYPE; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; KOREA; LYMPHOMA, LARGE B-CELL, DIFFUSE; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PREDNISONE; PROGNOSIS; RISK; TREATMENT OUTCOME; VINCRISTINE;

EID: 77950349305     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2009.12.004     Document Type: Article

References (33)

1. World Health Organization Classification of Tumors. Pathology and Genetics of Tumors of Haematopoietic and Lymphoid Tissues 2001, IARC Press, Lyon, France. H.N. Jaffe ES, H. Stein, J.W. Vardiman (Eds.).
2. Feugier P., Van Hoof A., Sebban C., Solal-Celigny P., Bouabdallah R., Ferme C., Christian B., Lepage E., Tilly H., Morschhauser F., Gaulard P., Salles G., Bosly A., Gisselbrecht C., Reyes F., Coiffier B. Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: a study by the Groupe d'Etude des Lymphomes de l'Adulte. J Clin Oncol 2005, 23:4117-4126.
3. Pfreundschuh M., Trumper L., Osterborg A., Pettengell R., Trneny M., Imrie K., Ma D., Gill D., Walewski J., Zinzani P.L., Stahel R., Kvaloy S., Shpilberg O., Jaeger U., Hansen M., Lehtinen T., Lopez-Guillermo A., Corrado C., Scheliga A., Milpied N., Mendila M., Rashford M., Kuhnt E., Loeffler M. CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group. Lancet Oncol 2006, 7:379-391.
4. Zhang J., Tian Q., Yung Chan S., Chuen Li S., Zhou S., Duan W., Zhu Y.Z. Metabolism and transport of oxazaphosphorines and the clinical implications. Drug Metabol Rev 2005, 37:611-703.
5. Dirven H.A., van Ommen B., van Bladeren P.J. Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione. Cancer Res 1994, 54:6215-6220.
6. van Ommen B., Bogaards J.J., Peters W.H., Blaauboer B., van Bladeren P.J. Quantification of human hepatic glutathione S-transferases. Biochem J 1990, 269:609-613.
7. Tew K.D. Glutathione-associated enzymes in anticancer drug resistance. Cancer research 1994, 54:4313-4320.
8. Joel S.P., Rohatine A. Pharmacology of Antileukemic Drugs 2002, Saunders, Philadelphia.
9. Rosazza J.P., Duffel M.W., el-Marakby S., Ahn S.H. Metabolism of the Catharanthus alkaloids: from Streptomyces griseus to monoamine oxidase B. J Natural Prod 1992, 55:269-284.
10. Depeille P., Cuq P., Mary S., Passagne I., Evrard A., Cupissol D., Vian L. Glutathione S-transferase M1 and multidrug resistance protein 1 act in synergy to protect melanoma cells from vincristine effects. Mol Pharmacol 2004, 65:897-905.
11. Homma H., Maruyama H., Niitsu Y., Listowsky I. A subclass of glutathione S-transferases as intracellular high-capacity and high-affinity steroid-binding proteins. Biochem J 1986, 235:763-768.
12. High capacity binding by glutathione S-transferases and glucocorticoid resistance 1993, CRC Press, Boca Raton. I. Listowsky (Ed.).
13. Cheson B.D., Horning S.J., Coiffier B., Shipp M.A., Fisher R.I., Connors J.M., Lister T.A., Vose J., Grillo-Lopez A., Hagenbeek A., Cabanillas F., Klippensten D., Hiddemann W., Castellino R., Harris N.L., Armitage J.O., Carter W., Hoppe R., Canellos G.P. Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. NCI Sponsored International Working Group. J Clin Oncol 1999, 17:1244.
14. Cancer Therapy Evaluation Program. Terminology Criteria for Adverse Effects, version 3.0 2003, National Institutes of Health USDoHaHS, National Cancer Institute, Bethesda.
15. Abdel-Rahman S.Z., el-Zein R.A., Anwar W.A., Au W.W. A multiplex PCR procedure for polymorphic analysis of GSTM1 and GSTT1 genes in population studies. Cancer Lett 1996, 107:229-233.
16. Cho H.J., Lee S.Y., Ki C.S., Kim J.W. GSTM1, GSTT1 and GSTP1 polymorphisms in the Korean population. J Korean Med Sci 2005, 20:1089-1092.
17. Choi S.C., Yun K.J., Kim T.H., Kim H.J., Park S.G., Oh G.J., Chae S.C., Oh G.J., Nah Y.H., Kim J.J., Chung H.T. Prognostic potential of glutathione S-transferase M1 and T1 null genotypes for gastric cancer progression. Cancer Lett 2003, 195:169-175.
18. Yim J.J., Yoo C.G., Lee C.T., Kim Y.W., Han S.K., Shim Y.S. Lack of association between glutathione S-transferase P1 polymorphism and COPD in Koreans. Lung 2002, 180:119-125.
19. Zhong S., Huang M., Yang X., Liang L., Wang Y., Romkes M., Duan W., Chan E., Zhou S.F. Relationship of glutathione S-transferase genotypes with side-effects of pulsed cyclophosphamide therapy in patients with systemic lupus erythematosus. Br J Clin Pharmacol 2006, 62:457-472.
20. Davies S.M., Robison L.L., Buckley J.D., Tjoa T., Woods W.G., Radloff G.A., Ross J.A., Perentesis J.P. Glutathione S-transferase polymorphisms and outcome of chemotherapy in childhood acute myeloid leukemia. J Clin Oncol 2001, 19:1279-1287.
21. Naoe T., Tagawa Y., Kiyoi H., Kodera Y., Miyawaki S., Asou N., Kuriyama K., Kusumoto S., Shimazaki C., Saito K., Akiyama H., Motoji T., Nishimura M., Shinagawa K., Ueda R., Saito H., Ohno R. Prognostic significance of the null genotype of glutathione S-transferase-T1 in patients with acute myeloid leukemia: increased early death after chemotherapy. Leukemia 2002, 16:203-208.
22. Sanchez R.I., Mesia-Vela S., Kauffman F.C. Induction of NAD(P)H quinone oxidoreductase and glutathione S-transferase activities in livers of female August-Copenhagen Irish rats treated chronically with estradiol: comparison with the Sprague-Dawley rat. J Steroid Biochem Mol Biol 2003, 87:199-206.
23. Barragan E., Collado M., Cervera J., Martin G., Bolufer P., Roman J., Sanz M.A. The GST deletions and NQO1*2 polymorphism confers interindividual variability of response to treatment in patients with acute myeloid leukemia. Leuk Res 2007, 31:947-953.
24. Ambrosone C.B., Sweeney C., Coles B.F., Thompson P.A., McClure G.Y., Korourian S., Fares M.Y., Stone A., Kadlubar F.F., Hutchins L.F. Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer. Cancer Res 2001, 61:7130-7135.
25. Stanulla M., Schrappe M., Brechlin A.M., Zimmermann M., Welte K. Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study. Blood 2000, 95:1222-1228.
26. Voso M.T., D'Alo F., Putzulu R., Mele L., Scardocci A., Chiusolo P., Latagliata R., Lo-Coco F., Rutella S., Pagano L., Hohaus S., Leone G. Negative prognostic value of glutathione S-transferase (GSTM1 and GSTT1) deletions in adult acute myeloid leukemia. Blood 2002, 100:2703-2707.
27. Takanashi M., Morimoto A., Yagi T., Kuriyama K., Kano G., Imamura T., Hibi S., Todo S., Imashuku S. Impact of glutathione S-transferase gene deletion on early relapse in childhood B-precursor acute lymphoblastic leukemia. Haematologica 2003, 88:1238-1244.
28. Hohaus S., Mansueto G., Massini G., D'Alo F., Giachelia M., Martini M., Larocca L.M., Voso M.T., Leone G. Glutathione-S-transferase genotypes influence prognosis in follicular non-Hodgkin's Lymphoma. Leuk Lymph 2007, 48:564-569.
29. Dieckvoss B.O., Stanulla M., Schrappe M., Beier R., Zimmermann M., Welte K., Reiter A. Polymorphisms within glutathione S-transferase genes in pediatric non-Hodgkin's lymphoma. Haematologica 2002, 87:709-713. [Discussion, 13].
30. Howells R.E., Redman C.W., Dhar K.K., Sarhanis P., Musgrove C., Jones P.W., Alldersea J., Fryer A.A., Hoban P.R., Strange R.C. Association of glutathione S-transferase GSTM1 and GSTT1 null genotypes with clinical outcome in epithelial ovarian cancer. Clin Cancer Res 1998, 4:2439-2445.
31. Howells R.E., Holland T., Dhar K.K., Redman C.W., Hand P., Hoban P.R., Jones P.W., Fryer A.A., Strange R.C. Glutathione S-transferase GSTM1 and GSTT1 genotypes in ovarian cancer: association with p53 expression and survival. Int J Gynecol Cancer 2001, 11:107-112.
32. Nakamichi I., Tomita Y., Zhang B., Sugiyama H., Kanakura Y., Fukuhara S., Hino M., Kanamaru A., Ogawa H., Aozasa K. Correlation between promoter hypermethylation of GSTP1 and response to chemotherapy in diffuse large B cell lymphoma. Ann Hematol 2007, 86:557-564.
33. Hohaus S., Di Ruscio A., Di Febo A., Massini G., D'Alo F., Guidi F., Mansueto G., Voso M.T., Leone G. Glutathione S-transferase P1 genotype and prognosis in Hodgkin's lymphoma. Clin Cancer Res 2005, 11:2175-2179.