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Volumn 11, Issue 4, 2010, Pages 383-390

Molecular epidemiology and its current clinical use in cancer management

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CYCLOPHOSPHAMIDE; CYTOCHROME P450 2D6; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FLUOROURACIL; PACLITAXEL; PROSTATE SPECIFIC ANTIGEN; TAMOXIFEN; TRASTUZUMAB;

EID: 77950308676     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(10)70005-X     Document Type: Review
Times cited : (35)

References (81)
  • 1
    • 7244245762 scopus 로고    scopus 로고
    • Finishing the euchromatic sequence of the human genome
    • Finishing the euchromatic sequence of the human genome. Nature 2004, 431:931-945.
    • (2004) Nature , vol.431 , pp. 931-945
  • 2
    • 27344436618 scopus 로고    scopus 로고
    • Genomics. New haplotype map may overhaul gene hunting
    • Couzin J Genomics. New haplotype map may overhaul gene hunting. Science 2005, 310:601.
    • (2005) Science , vol.310 , pp. 601
    • Couzin, J.1
  • 3
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • A haplotype map of the human genome. Nature 2005, 437:1299-1320.
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 4
    • 34250305146 scopus 로고    scopus 로고
    • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    • Birney E, Stamatoyannopoulos JA, Dutta A, et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007, 447:799-816.
    • (2007) Nature , vol.447 , pp. 799-816
    • Birney, E.1    Stamatoyannopoulos, J.A.2    Dutta, A.3
  • 5
    • 70349956433 scopus 로고    scopus 로고
    • Finding the missing heritability of complex diseases
    • Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature 2009, 461:747-753.
    • (2009) Nature , vol.461 , pp. 747-753
    • Manolio, T.A.1    Collins, F.S.2    Cox, N.J.3
  • 6
    • 66349121862 scopus 로고    scopus 로고
    • The HapMap and genome-wide association studies in diagnosis and therapy
    • Manolio TA, Collins FS The HapMap and genome-wide association studies in diagnosis and therapy. Annu Rev Med 2009, 60:443-456.
    • (2009) Annu Rev Med , vol.60 , pp. 443-456
    • Manolio, T.A.1    Collins, F.S.2
  • 7
    • 41649109807 scopus 로고    scopus 로고
    • Translating insights from the cancer genome into clinical practice
    • Chin L, Gray JW Translating insights from the cancer genome into clinical practice. Nature 2008, 452:553-563.
    • (2008) Nature , vol.452 , pp. 553-563
    • Chin, L.1    Gray, J.W.2
  • 8
    • 33947393565 scopus 로고    scopus 로고
    • Mapping the cancer genome. Pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies
    • Collins FS, Barker AD Mapping the cancer genome. Pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies. Sci Am 2007, 296:50-57.
    • (2007) Sci Am , vol.296 , pp. 50-57
    • Collins, F.S.1    Barker, A.D.2
  • 9
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature 2000, 406:747-752.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 10
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van't Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002, 415:530-536.
    • (2002) Nature , vol.415 , pp. 530-536
    • van't Veer, L.J.1    Dai, H.2    van de Vijver, M.J.3
  • 11
    • 60849097255 scopus 로고    scopus 로고
    • Gene-expression signatures in breast cancer
    • Sotiriou C, Pusztai L Gene-expression signatures in breast cancer. N Engl J Med 2009, 360:790-800.
    • (2009) N Engl J Med , vol.360 , pp. 790-800
    • Sotiriou, C.1    Pusztai, L.2
  • 12
    • 0035747593 scopus 로고    scopus 로고
    • Interpreting and integrating risk factors for patients with primary breast cancer
    • Clark GM Interpreting and integrating risk factors for patients with primary breast cancer. J Natl Cancer Inst Monogr 2001, 30:17-21.
    • (2001) J Natl Cancer Inst Monogr , vol.30 , pp. 17-21
    • Clark, G.M.1
  • 13
    • 62549085618 scopus 로고    scopus 로고
    • Human genetic variation and its contribution to complex traits
    • Frazer KA, Murray SS, Schork NJ, Topol EJ Human genetic variation and its contribution to complex traits. Nat Rev Genet 2009, 10:241-251.
    • (2009) Nat Rev Genet , vol.10 , pp. 241-251
    • Frazer, K.A.1    Murray, S.S.2    Schork, N.J.3    Topol, E.J.4
  • 14
    • 67349237973 scopus 로고    scopus 로고
    • Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2
    • Ahmed S, Thomas G, Ghoussaini M, et al. Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet 2009, 41:585-590.
    • (2009) Nat Genet , vol.41 , pp. 585-590
    • Ahmed, S.1    Thomas, G.2    Ghoussaini, M.3
  • 15
    • 34250006413 scopus 로고    scopus 로고
    • Genome-wide association study identifies novel breast cancer susceptibility loci
    • Easton DF, Pooley KA, Dunning AM, et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007, 447:1087-1093.
    • (2007) Nature , vol.447 , pp. 1087-1093
    • Easton, D.F.1    Pooley, K.A.2    Dunning, A.M.3
  • 16
    • 33847337318 scopus 로고    scopus 로고
    • A common coding variant in CASP8 is associated with breast cancer risk
    • Cox A, Dunning AM, Garcia-Closas M, et al. A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet 2007, 39:352-358.
    • (2007) Nat Genet , vol.39 , pp. 352-358
    • Cox, A.1    Dunning, A.M.2    Garcia-Closas, M.3
  • 17
    • 39749129053 scopus 로고    scopus 로고
    • Multiple newly identified loci associated with prostate cancer susceptibility
    • Eeles RA, Kote-Jarai Z, Giles GG, et al. Multiple newly identified loci associated with prostate cancer susceptibility. Nat Genet 2008, 40:316-321.
    • (2008) Nat Genet , vol.40 , pp. 316-321
    • Eeles, R.A.1    Kote-Jarai, Z.2    Giles, G.G.3
  • 18
    • 52949115663 scopus 로고    scopus 로고
    • Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12
    • Sun J, Zheng SL, Wiklund F, et al. Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12. Nat Genet 2008, 40:1153-1155.
    • (2008) Nat Genet , vol.40 , pp. 1153-1155
    • Sun, J.1    Zheng, S.L.2    Wiklund, F.3
  • 19
    • 66149110014 scopus 로고    scopus 로고
    • A novel prostate cancer susceptibility locus at 19q13
    • Hsu FC, Sun J, Wiklund F, et al. A novel prostate cancer susceptibility locus at 19q13. Cancer Res 2009, 69:2720-2723.
    • (2009) Cancer Res , vol.69 , pp. 2720-2723
    • Hsu, F.C.1    Sun, J.2    Wiklund, F.3
  • 20
    • 39749159112 scopus 로고    scopus 로고
    • Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer
    • Gudmundsson J, Sulem P, Rafnar T, et al. Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet 2008, 40:281-283.
    • (2008) Nat Genet , vol.40 , pp. 281-283
    • Gudmundsson, J.1    Sulem, P.2    Rafnar, T.3
  • 21
    • 46849098205 scopus 로고    scopus 로고
    • Multiple loci with different cancer specificities within the 8q24 gene desert
    • Ghoussaini M, Song H, Koessler T, et al. Multiple loci with different cancer specificities within the 8q24 gene desert. J Natl Cancer Inst 2008, 100:962-966.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 962-966
    • Ghoussaini, M.1    Song, H.2    Koessler, T.3
  • 22
    • 45949085378 scopus 로고    scopus 로고
    • Polygenes, risk prediction, and targeted prevention of breast cancer
    • Pharoah PD, Antoniou AC, Easton DF, Ponder BA Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med 2008, 358:2796-2803.
    • (2008) N Engl J Med , vol.358 , pp. 2796-2803
    • Pharoah, P.D.1    Antoniou, A.C.2    Easton, D.F.3    Ponder, B.A.4
  • 23
    • 0028806048 scopus 로고
    • Quantitative monitoring of gene expression patterns with a complementary DNA microarray
    • Schena M, Shalon D, Davis RW, Brown PO Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995, 270:467-470.
    • (1995) Science , vol.270 , pp. 467-470
    • Schena, M.1    Shalon, D.2    Davis, R.W.3    Brown, P.O.4
  • 25
    • 41649114164 scopus 로고    scopus 로고
    • Enabling personalized cancer medicine through analysis of gene-expression patterns
    • van't Veer LJ, Bernards R Enabling personalized cancer medicine through analysis of gene-expression patterns. Nature 2008, 452:564-570.
    • (2008) Nature , vol.452 , pp. 564-570
    • van't Veer, L.J.1    Bernards, R.2
  • 26
    • 70350710119 scopus 로고    scopus 로고
    • Rethinking screening for breast cancer and prostate cancer
    • Esserman L, Shieh Y, Thompson I Rethinking screening for breast cancer and prostate cancer. JAMA 2009, 302:1685-1692.
    • (2009) JAMA , vol.302 , pp. 1685-1692
    • Esserman, L.1    Shieh, Y.2    Thompson, I.3
  • 27
    • 47649099448 scopus 로고    scopus 로고
    • Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk
    • Gail MH Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk. J Natl Cancer Inst 2008, 100:1037-1041.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1037-1041
    • Gail, M.H.1
  • 28
    • 65949104586 scopus 로고    scopus 로고
    • Genomewide association studies and human disease
    • Hardy J, Singleton A Genomewide association studies and human disease. N Engl J Med 2009, 360:1759-1768.
    • (2009) N Engl J Med , vol.360 , pp. 1759-1768
    • Hardy, J.1    Singleton, A.2
  • 29
    • 65949107547 scopus 로고    scopus 로고
    • Common genetic variation and human traits
    • Goldstein DB Common genetic variation and human traits. N Engl J Med 2009, 360:1696-1698.
    • (2009) N Engl J Med , vol.360 , pp. 1696-1698
    • Goldstein, D.B.1
  • 30
    • 65949099120 scopus 로고    scopus 로고
    • Genetic risk prediction-are we there yet?
    • Kraft P, Hunter DJ Genetic risk prediction-are we there yet?. N Engl J Med 2009, 360:1701-1703.
    • (2009) N Engl J Med , vol.360 , pp. 1701-1703
    • Kraft, P.1    Hunter, D.J.2
  • 31
    • 29144475553 scopus 로고    scopus 로고
    • Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials
    • Clarke M, Collins R, Darby S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005, 366:2087-2106.
    • (2005) Lancet , vol.366 , pp. 2087-2106
    • Clarke, M.1    Collins, R.2    Darby, S.3
  • 35
    • 43249123378 scopus 로고    scopus 로고
    • Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
    • Garcia-Closas M, Hall P, Nevanlinna H, et al. Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet 2008, 4:e1000054.
    • (2008) PLoS Genet , vol.4
    • Garcia-Closas, M.1    Hall, P.2    Nevanlinna, H.3
  • 36
    • 0642335059 scopus 로고    scopus 로고
    • Allelic diversity in the host genetic background may be an important determinant in tumor metastatic dissemination
    • Hunter KW Allelic diversity in the host genetic background may be an important determinant in tumor metastatic dissemination. Cancer Lett 2003, 200:97-105.
    • (2003) Cancer Lett , vol.200 , pp. 97-105
    • Hunter, K.W.1
  • 37
    • 33750598939 scopus 로고    scopus 로고
    • The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer
    • Ma XJ, Hilsenbeck SG, Wang W, et al. The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer. J Clin Oncol 2006, 24:4611-4619.
    • (2006) J Clin Oncol , vol.24 , pp. 4611-4619
    • Ma, X.J.1    Hilsenbeck, S.G.2    Wang, W.3
  • 38
    • 52049095087 scopus 로고    scopus 로고
    • A five-gene molecular grade index and HOXB13:IL17BR are complementary prognostic factors in early stage breast cancer
    • Ma XJ, Salunga R, Dahiya S, et al. A five-gene molecular grade index and HOXB13:IL17BR are complementary prognostic factors in early stage breast cancer. Clin Cancer Res 2008, 14:2601-2608.
    • (2008) Clin Cancer Res , vol.14 , pp. 2601-2608
    • Ma, X.J.1    Salunga, R.2    Dahiya, S.3
  • 39
    • 73949136029 scopus 로고    scopus 로고
    • The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade
    • Weigelt B, Baehner FL, Reis-Filho JS The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade. J Pathol 2010, 220:263-280.
    • (2010) J Pathol , vol.220 , pp. 263-280
    • Weigelt, B.1    Baehner, F.L.2    Reis-Filho, J.S.3
  • 40
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005, 365:1687-1717. Early Breast Cancer Trialists' Collaborative Group (EBCTCG).
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 41
    • 51049104630 scopus 로고    scopus 로고
    • Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial
    • Bill-Axelson A, Holmberg L, Filen F, et al. Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial. J Natl Cancer Inst 2008, 100:1144-1154.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1144-1154
    • Bill-Axelson, A.1    Holmberg, L.2    Filen, F.3
  • 42
    • 34547094447 scopus 로고    scopus 로고
    • Molecular Classification of Breast Tumors Toward Improved Diagnostics and Treatments
    • Sørlie T Molecular Classification of Breast Tumors Toward Improved Diagnostics and Treatments. Methods Mol Biol 2007, 360:91-114.
    • (2007) Methods Mol Biol , vol.360 , pp. 91-114
    • Sørlie, T.1
  • 43
    • 36349024762 scopus 로고    scopus 로고
    • Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes
    • Schroth W, Antoniadou L, Fritz P, et al. Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes. J Clin Oncol 2007, 25:5187-5193.
    • (2007) J Clin Oncol , vol.25 , pp. 5187-5193
    • Schroth, W.1    Antoniadou, L.2    Fritz, P.3
  • 44
    • 33644639136 scopus 로고    scopus 로고
    • Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes
    • Goetz MP, Rae JM, Suman VJ, et al. Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes. J Clin Oncol 2005, 23:9312-9318.
    • (2005) J Clin Oncol , vol.23 , pp. 9312-9318
    • Goetz, M.P.1    Rae, J.M.2    Suman, V.J.3
  • 46
    • 70349929431 scopus 로고    scopus 로고
    • Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen
    • Schroth W, Goetz MP, Hamann U, et al. Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen. JAMA 2009, 302:1429-1436.
    • (2009) JAMA , vol.302 , pp. 1429-1436
    • Schroth, W.1    Goetz, M.P.2    Hamann, U.3
  • 47
    • 34248208754 scopus 로고    scopus 로고
    • Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer
    • Wegman P, Elingarami S, Carstensen J, Stal O, Nordenskjold B, Wingren S Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer. Breast Cancer Res 2007, 9:R7.
    • (2007) Breast Cancer Res , vol.9
    • Wegman, P.1    Elingarami, S.2    Carstensen, J.3    Stal, O.4    Nordenskjold, B.5    Wingren, S.6
  • 48
    • 70349240709 scopus 로고    scopus 로고
    • PARP inhibitors: will the new class of drugs match the hype?
    • Tuma RS PARP inhibitors: will the new class of drugs match the hype?. J Natl Cancer Inst 2009, 101:1230-1232.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1230-1232
    • Tuma, R.S.1
  • 49
    • 77950304120 scopus 로고    scopus 로고
    • Phase II trial of the oral PARP inhibitor olaparib in BRCA-deficient advanced breast cancer. 2009 ASCO Annual Meeting, Orlando, FL, USA; May 29-June 2.
    • Tutt A, Robson M, Garber JE, et al. Phase II trial of the oral PARP inhibitor olaparib in BRCA-deficient advanced breast cancer. 2009 ASCO Annual Meeting, Orlando, FL, USA; May 29-June 2.
    • Tutt, A.1    Robson, M.2    Garber, J.E.3
  • 50
    • 77950308650 scopus 로고    scopus 로고
    • Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer. ASCO Annual Meeting, Orlando, FL, USA; May 29-June 2.
    • Audeh MW, Penson RT, Friedlander M, et al. Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer. 2009 ASCO Annual Meeting, Orlando, FL, USA; May 29-June 2.
    • (2009)
    • Audeh, M.W.1    Penson, R.T.2    Friedlander, M.3
  • 51
    • 77950317605 scopus 로고    scopus 로고
    • Efficacy of BSI-201, a poly (ADP-ribose) polymerase-1 (PARP1) inhibitor, in combination with gemcitabine/carboplatin (G/C) in patients with metastatic triple-negative breast cancer (TNBC): Results of a randomized phase II trial. 2009 ASCO Annual Meeting, Orlando, FL, USA; May 29-June 2.
    • O'Shaughnessy J, Osborne C, Pippen J, et al. Efficacy of BSI-201, a poly (ADP-ribose) polymerase-1 (PARP1) inhibitor, in combination with gemcitabine/carboplatin (G/C) in patients with metastatic triple-negative breast cancer (TNBC): Results of a randomized phase II trial. 2009 ASCO Annual Meeting, Orlando, FL, USA; May 29-June 2.
    • O'Shaughnessy, J.1    Osborne, C.2    Pippen, J.3
  • 52
    • 39749137117 scopus 로고    scopus 로고
    • Inherited variation in the androgen pathway is associated with the efficacy of androgen-deprivation therapy in men with prostate cancer
    • Ross RW, Oh WK, Xie W, et al. Inherited variation in the androgen pathway is associated with the efficacy of androgen-deprivation therapy in men with prostate cancer. J Clin Oncol 2008, 26:842-847.
    • (2008) J Clin Oncol , vol.26 , pp. 842-847
    • Ross, R.W.1    Oh, W.K.2    Xie, W.3
  • 53
    • 67649935641 scopus 로고    scopus 로고
    • Genomic approaches to outcome prediction in prostate cancer
    • Febbo PG Genomic approaches to outcome prediction in prostate cancer. Cancer 2009, 115:3046-3057.
    • (2009) Cancer , vol.115 , pp. 3046-3057
    • Febbo, P.G.1
  • 54
    • 59249100224 scopus 로고    scopus 로고
    • Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia
    • Yang JJ, Cheng C, Yang W, et al. Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. JAMA 2009, 301:393-403.
    • (2009) JAMA , vol.301 , pp. 393-403
    • Yang, J.J.1    Cheng, C.2    Yang, W.3
  • 55
    • 38149015568 scopus 로고    scopus 로고
    • Critical review of microarray-based prognostic tests and trials in breast cancer
    • Koscielny S Critical review of microarray-based prognostic tests and trials in breast cancer. Curr Opin Obstet Gynecol 2008, 20:47-50.
    • (2008) Curr Opin Obstet Gynecol , vol.20 , pp. 47-50
    • Koscielny, S.1
  • 56
    • 24744445401 scopus 로고    scopus 로고
    • Loss of epigenetic control of synuclein-gamma gene as a molecular indicator of metastasis in a wide range of human cancers
    • Liu H, Liu W, Wu Y, et al. Loss of epigenetic control of synuclein-gamma gene as a molecular indicator of metastasis in a wide range of human cancers. Cancer Res 2005, 65:7635-7643.
    • (2005) Cancer Res , vol.65 , pp. 7635-7643
    • Liu, H.1    Liu, W.2    Wu, Y.3
  • 57
    • 2542418468 scopus 로고    scopus 로고
    • Gene-expression profiles and breast-cancer prognosis
    • Master SR, Mies C Gene-expression profiles and breast-cancer prognosis. Adv Anat Pathol 2003, 10:338-346.
    • (2003) Adv Anat Pathol , vol.10 , pp. 338-346
    • Master, S.R.1    Mies, C.2
  • 58
    • 2942578063 scopus 로고    scopus 로고
    • A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
    • Ma XJ, Wang Z, Ryan PD, et al. A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell 2004, 5:607-616.
    • (2004) Cancer Cell , vol.5 , pp. 607-616
    • Ma, X.J.1    Wang, Z.2    Ryan, P.D.3
  • 59
    • 20044377912 scopus 로고    scopus 로고
    • Molecular classification of tamoxifen-resistant breast carcinomas by gene expression profiling
    • Jansen MP, Foekens JA, van Staveren IL, et al. Molecular classification of tamoxifen-resistant breast carcinomas by gene expression profiling. J Clin Oncol 2005, 23:732-740.
    • (2005) J Clin Oncol , vol.23 , pp. 732-740
    • Jansen, M.P.1    Foekens, J.A.2    van Staveren, I.L.3
  • 60
    • 35748937074 scopus 로고    scopus 로고
    • Clinical and therapeutic perspectives of gene expression profiling for breast cancer
    • Chiuri VE, Leo G, Lorusso V Clinical and therapeutic perspectives of gene expression profiling for breast cancer. Ann Oncol 2007, 18(suppl 6):58-62.
    • (2007) Ann Oncol , vol.18 , Issue.SUPPL. 6 , pp. 58-62
    • Chiuri, V.E.1    Leo, G.2    Lorusso, V.3
  • 61
    • 33947246109 scopus 로고    scopus 로고
    • Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer
    • Harris LN, You F, Schnitt SJ, et al. Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer. Clin Cancer Res 2007, 13:1198-1207.
    • (2007) Clin Cancer Res , vol.13 , pp. 1198-1207
    • Harris, L.N.1    You, F.2    Schnitt, S.J.3
  • 62
    • 22344446693 scopus 로고    scopus 로고
    • Neoadjuvant docetaxel before radical prostatectomy in patients with high-risk localized prostate cancer
    • Febbo PG, Richie JP, George DJ, et al. Neoadjuvant docetaxel before radical prostatectomy in patients with high-risk localized prostate cancer. Clin Cancer Res 2005, 11:5233-5240.
    • (2005) Clin Cancer Res , vol.11 , pp. 5233-5240
    • Febbo, P.G.1    Richie, J.P.2    George, D.J.3
  • 63
    • 1842612441 scopus 로고    scopus 로고
    • Molecular determinants of resistance to antiandrogen therapy
    • Chen CD, Welsbie DS, Tran C, et al. Molecular determinants of resistance to antiandrogen therapy. Nat Med 2004, 10:33-39.
    • (2004) Nat Med , vol.10 , pp. 33-39
    • Chen, C.D.1    Welsbie, D.S.2    Tran, C.3
  • 64
    • 65349089474 scopus 로고    scopus 로고
    • Genomic strategy for targeting therapy in castration-resistant prostate cancer
    • Mendiratta P, Mostaghel E, Guinney J, et al. Genomic strategy for targeting therapy in castration-resistant prostate cancer. J Clin Oncol 2009, 27:2022-2029.
    • (2009) J Clin Oncol , vol.27 , pp. 2022-2029
    • Mendiratta, P.1    Mostaghel, E.2    Guinney, J.3
  • 65
    • 68349126950 scopus 로고    scopus 로고
    • Microarray-based gene expression profiling as a clinical tool for breast cancer management: are we there yet?
    • Correa Geyer F, Reis-Filho JS Microarray-based gene expression profiling as a clinical tool for breast cancer management: are we there yet?. Int J Surg Pathol 2009, 17:285-302.
    • (2009) Int J Surg Pathol , vol.17 , pp. 285-302
    • Correa Geyer, F.1    Reis-Filho, J.S.2
  • 66
    • 78649365002 scopus 로고    scopus 로고
    • Predicting prostate cancer behavior using transcript profiles
    • Nelson PS Predicting prostate cancer behavior using transcript profiles. J Urol 2004, 172:S28-S32.
    • (2004) J Urol , vol.172
    • Nelson, P.S.1
  • 67
    • 37549055451 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in oestrogen-receptor-poor breast cancer: patient-level meta-analysis of randomised trials
    • Clarke M, Coates AS, Darby SC, et al. Adjuvant chemotherapy in oestrogen-receptor-poor breast cancer: patient-level meta-analysis of randomised trials. Lancet 2008, 371:29-40.
    • (2008) Lancet , vol.371 , pp. 29-40
    • Clarke, M.1    Coates, A.S.2    Darby, S.C.3
  • 68
    • 58149354867 scopus 로고    scopus 로고
    • Quo vadis with targeted drugs in the 21st century?
    • Bergh J Quo vadis with targeted drugs in the 21st century?. J Clin Oncol 2009, 27:2-5.
    • (2009) J Clin Oncol , vol.27 , pp. 2-5
    • Bergh, J.1
  • 69
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001, 98:10869-10874.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.M.2    Tibshirani, R.3
  • 70
    • 26444546442 scopus 로고    scopus 로고
    • An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival
    • Miller LD, Smeds J, George J, et al. An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. Proc Natl Acad Sci USA 2005, 102:13550-13555.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13550-13555
    • Miller, L.D.1    Smeds, J.2    George, J.3
  • 71
    • 58149330982 scopus 로고    scopus 로고
    • Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures
    • Wirapati P, Sotiriou C, Kunkel S, et al. Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures. Breast Cancer Res 2008, 10:R65.
    • (2008) Breast Cancer Res , vol.10
    • Wirapati, P.1    Sotiriou, C.2    Kunkel, S.3
  • 72
    • 33745926178 scopus 로고    scopus 로고
    • Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing
    • Thomas RK, Nickerson E, Simons JF, et al. Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing. Nat Med 2006, 12:852-855.
    • (2006) Nat Med , vol.12 , pp. 852-855
    • Thomas, R.K.1    Nickerson, E.2    Simons, J.F.3
  • 73
    • 41649102043 scopus 로고    scopus 로고
    • The cancer biomarker problem
    • Sawyers CL The cancer biomarker problem. Nature 2008, 452:548-552.
    • (2008) Nature , vol.452 , pp. 548-552
    • Sawyers, C.L.1
  • 74
    • 6044278144 scopus 로고    scopus 로고
    • Evaluating the efficiency of targeted designs for randomized clinical trials
    • Simon R, Maitournam A Evaluating the efficiency of targeted designs for randomized clinical trials. Clin Cancer Res 2004, 10:6759-6763.
    • (2004) Clin Cancer Res , vol.10 , pp. 6759-6763
    • Simon, R.1    Maitournam, A.2
  • 75
    • 22344446208 scopus 로고    scopus 로고
    • Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group
    • Marty M, Cognetti F, Maraninchi D, et al. Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group. J Clin Oncol 2005, 23:4265-4274.
    • (2005) J Clin Oncol , vol.23 , pp. 4265-4274
    • Marty, M.1    Cognetti, F.2    Maraninchi, D.3
  • 76
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001, 344:783-792.
    • (2001) N Engl J Med , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 77
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003, 349:2042-2054.
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 78
    • 0037115392 scopus 로고    scopus 로고
    • Dependence of histone modifications and gene expression on DNA hypermethylation in cancer
    • Fahrner JA, Eguchi S, Herman JG, Baylin SB Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. Cancer Res 2002, 62:7213-7218.
    • (2002) Cancer Res , vol.62 , pp. 7213-7218
    • Fahrner, J.A.1    Eguchi, S.2    Herman, J.G.3    Baylin, S.B.4
  • 79
    • 33845319262 scopus 로고    scopus 로고
    • Epigenetic inactivation of the HOXA gene cluster in breast cancer
    • Novak P, Jensen T, Oshiro MM, et al. Epigenetic inactivation of the HOXA gene cluster in breast cancer. Cancer Res 2006, 66:10664-10667.
    • (2006) Cancer Res , vol.66 , pp. 10664-10667
    • Novak, P.1    Jensen, T.2    Oshiro, M.M.3
  • 80
    • 66649105473 scopus 로고    scopus 로고
    • Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas
    • Stewart DJ, Issa JP, Kurzrock R, et al. Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas. Clin Cancer Res 2009, 15:3881-3888.
    • (2009) Clin Cancer Res , vol.15 , pp. 3881-3888
    • Stewart, D.J.1    Issa, J.P.2    Kurzrock, R.3
  • 81
    • 33846973361 scopus 로고    scopus 로고
    • Inheritance of a cancer-associated MLH1 germ-line epimutation
    • Hitchins MP, Wong JJ, Suthers G, et al. Inheritance of a cancer-associated MLH1 germ-line epimutation. N Engl J Med 2007, 356:697-705.
    • (2007) N Engl J Med , vol.356 , pp. 697-705
    • Hitchins, M.P.1    Wong, J.J.2    Suthers, G.3


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