A novel glucosyltransferase from Catharanthus roseus cell suspensions

Process Biochemistry

Volumn 45, Issue 5, 2010, Pages 655-659

  Piovan, Anna ^a   Cozza, Giorgio ^a   Caniato, Rosy ^a   Moro, Stefano ^a   Filippini, Raffaella ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Biocatalysts; Biotransformations; Catharanthus roseus; Cell cultures; Glucosyltransferase; Purification

Indexed keywords

AROMATIC RINGS; BIOTRANSFORMATIONS; CATHARANTHUS ROSEUS; CELL SUSPENSION; CHALCONES; DIHYDROXYFLAVONE; DIVALENT IONS; ESCULETIN; FLAVONOIDS; GLUCOSYLTRANSFERASE; GLUCOSYLTRANSFERASES; GLYCOCONJUGATES; GLYCOSYLTRANSFERASES; OPTIMUM PH; OPTIMUM TEMPERATURE; PHENOLIC COMPOUNDS; POTENTIAL APPLICATIONS; PURIFIED ENZYME; SCOPOLETIN; SDS-POLYACRYLAMIDE GEL ELECTROPHORESIS; SODIUM IONS; STRUCTURAL FEATURE; SUBSTRATE SPECIFICITY; UMBELLIFERONE;

ELECTROPHORESIS; ENZYME ACTIVITY; ENZYMES; METAL IONS; PHENOLS; PURIFICATION; SUGAR (SUCROSE);

CELL CULTURE;

CATHARANTHUS ROSEUS;

EID: 77950298945     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2009.12.014     Document Type: Article

References (32)

1. Lim E.K., and Bowles D. A class of plant glycosyltransferase involved in cellular homeostasis. EMBO J 23 (2004) 2915-2922
2. Bowles D., Lsayenkova J., Lim E.K., and Poppenberg B. Glycosyltransferases: managers of small molecules. Curr Opin Plant Biol 8 (2005) 254-263
3. Jones P., and Vogt T. Glycosyltransferases in secondary plant metabolism: tranquilizers and stimulant controllers. Planta 213 (2001) 164-174
4. Bowles D., Lim E.K., Poppenberger B., and Vaistij F.E. Glycosyltransferase of lipophilic small molecules. Annu Rev Plant Biol 57 (2006) 567-597
5. Křen V., and Thiem J. Glycosylation employing bio-systems: from enzymes to whole cells. Chem Soc Rev 26 (1997) 463-473
6. Giri A., Dhingra V., Giri C.C., Singh A., Ward O.P., and Narasu M.L. Biotransformations using plant cells, organ cultures and enzyme systems: current trends and future prospects. Biotechnol Adv 19 (2001) 175-199
7. Lim E.K., Ashford D.A., Hou B.K., Jackson R.G., and Bowles D.J. Arabidopsis glycosyltransferases as biocatalysts in fermentation for regioselective synthesis of diverse quercetin glucosides. Biotechnol Bioeng 87 (2004) 623-631
8. Lim E.K. Plant glycosyltransferases: their potential as novel biocatalysts. Chem Eur J 11 (2005) 5486-5494
9. Schoemaker H.E., Mink D., and Wubbolts M.G. Dispelling the myths-biocatalysis in industrial synthesis. Science 299 (2003) 1694-1697
10. Thayer A. Enzymes at work. Chem Eng News 84 (2006) 15-25
11. Pollard D.J., and Woodley J.M. Biocatalysis for pharmaceutical intermediates: the future is now. Trends Biotechnol 25 (2007) 66-73
12. Fox R.J., and Huisman G.W. Enzyme optimization: moving from blind evolution to statistical exploration of sequence-function space. Trends Biotechnol 26 (2008) 132-138
13. Li L., Modolo L.V., Escamilla-Trevino L.L., Achnine L., Dixon R.A., and Wang X. Cristal structure of Medicago truncatula UGT8. J Mol Biol 370 (2007) 951-963
14. Murashige T., and Skoog F. A revised medium for rapid growth and bioassays in tobacco tissue culture. Physiol Plant 15 (1962) 473-497
15. Piovan A., Filippini R., Caniato R., Dalla Vecchia F., Innocenti G., Cappelletti E.M., et al. Somatic embryogenesis and indole alkaloid production in Catharanthus roseus. Plant Biosyst 134 (2000) 179-184
16. Bradford M. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 72 (1976) 248-254
17. Laemmli U.K. Cleavage of structural proteins during assembling of the head of bacteriophage T-4. Nature 270 (1970) 680-685
18. Saxby M.J. Characterization of flavonoids and coumarins by their absorption spectra on paper chromatograms. Anal Chem 36 (1964) 1145-1146
19. Vogt T., and Jones P. Glycosyltransferases in plant natural product synthesis: characterization of a supergene family. Trends Plant Sci 5 (2000) 380-386
20. Berim A., Ebel R., Schneider B., and Petersen M. UDP-glucose: (6-methoxy) podophyllotoxin 7-O-glucosyltranferase from suspension cultures of Linum nodiflorum. Phytochemistry 69 (2008) 374-381
21. Shao H., He X., Achnine L., Blount G.W., Dixon R.A., and Wang X. Cristal structures of a multifunctional triterpene/flavonoid glucosyltransferase from Medicago truncatula. Plant Cell 17 (2005) 3141-3154
22. Offen W., Martinez-Fleites C., Yang M., Lim E.K., Davis B.G., Tarling C.A., et al. Structure of a flavonoid glucosyltranferase reveals the basis for plant natural product modification. EMBO J 25 (2006) 1396-1405
23. Weis M., Lim E.K., Bruce N.C., and Bowles D.J. Enginering and kinetic characterization of two glucosyltransferases from Arabidopsis thaliana. Biochimie 90 (2008) 830-834
24. Ko J.H., Kim B.G., Kim J.H., Kim H., Lim C.E., Lim J., et al. Four glucosyltranferases from rice: cDNA cloning, expression, and characterization. J Plant Physiol 165 (2008) 435-444
25. Achnine L., Huhman D.V., Farag N.A., Sumner L.W., Blount J.W., and Dixon R.A. Genomics based selection and functional characterization of triterpene glycosyltransferases from the model legume Medicago truncatula. Plant J 41 (2005) 875-887
26. Kaminaga Y., Nagatsu A., Akiyama T., Sugimoto N., Yamazaki T., Maitani T., et al. Production of unnatural glucosydes of curcumin with drastically enhanced water solubility by cell suspension cultures of Catharanthus roseus. FEBS Lett 555 (2003) 311-316
27. Kaminaga Y., Sahin F.P., and Mizukami H. Molecular cloning and characterization of a glucosyltransferase catalyzing glucosylation of curcumin in cultured Catharanthus roseus cells. FEBS Lett 567 (2004) 197-202
28. Miller K.D., Guyon V., Evans J.N.S., Shuttleworth W.A., and Taylor L.P. Purification, cloning, and heterologous expression of a catalytically efficient flavonol 3-O-galactosyltransferase expressed in the male gametophyte of Petunia hybrida. J Biol Chem 274 (1999) 34011-34019
29. Hirotani M., Kuroda R., Suzuki H., and Yoshikawa T. Cloning and expression of UDP-glucose:flavonoid 7-O-glucosyltransferase from hairy root cultures of Scutellaria baicalensis. Planta 210 (2000) 1006-1013
30. Jones P., Messner B., Nakajima J.I., Schäffner A.R., and Saito K. UGT73C6 and UGT78D1, glycosyltransferses involved in flavonoid glycoside biosynthesis in Arabidopsis thaliana. J Biol Chem 278 (2003) 43910-43918
31. Kramer C.M., Prata R.T.N., Willits M.G., de Luca V., Steffens J.C., and Graser G. Cloning and regiospecificity studies of two flavonoid glucosyltransferases from Allium cepa. Phytochemistry 64 (2003) 1069-1076
32. Griesser M., Vitzthum F., Fink B., Bellido M.L., Raasch C., Munoz-Blanco J., et al. Multisubstrate flavonol O-glucosyltransferases from strawberry (Fragaria x ananassa) achene and receptacle. J Exp Bot 59 (2008) 2611-2625