메뉴 건너뛰기




Volumn 26, Issue 3, 2010, Pages 307-311

Short communication: High polymorphism rates in the HR1 and HR2 gp41 and presence of primary resistance-related mutations in HIV type 1 circulating in Brazil: Possible impact on enfuvirtide efficacy

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ENFUVIRTIDE; GLYCOPROTEIN GP 41; PROTEINASE; PROTEINASE B; REVERSE TRANSCRIPTASE B; RNA; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG;

EID: 77950228238     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2008.0297     Document Type: Article
Times cited : (9)

References (28)
  • 1
    • 24144489999 scopus 로고    scopus 로고
    • HIV-1 drug resistance evolution among patients on potent combination antiretroviral therapy with detectable viremia
    • Napravnik S, Edwards D, Stewart P, Stalzer B, Matteson E, and Eron JJ Jr: HIV-1 drug resistance evolution among patients on potent combination antiretroviral therapy with detectable viremia. J Acquir Immune Defic Syndr 2005; 40:34-40.
    • (2005) J Acquir Immune Defic Syndr , vol.40 , pp. 34-40
    • Napravnik, S.1    Edwards, D.2    Stewart, P.3    Stalzer, B.4    Matteson, E.5    JJ Jr. Eron6
  • 2
    • 0037169269 scopus 로고    scopus 로고
    • Duration and predictors of CD4 T-cell gains in patients who continue combination therapy despite detectable plasma viremia
    • Deeks SG, Barbour JD, Grant RM, and Martin JN: Duration and predictors of CD4 T-cell gains in patients who continue combination therapy despite detectable plasma viremia. AIDS 2002;16:201-220.
    • (2002) AIDS , vol.16 , pp. 201-220
    • Deeks, S.G.1    Barbour, J.D.2    Grant, R.M.3    Martin, J.N.4
  • 3
    • 8744267606 scopus 로고    scopus 로고
    • Long-term follow-up of HIV-infected individuals who have significant increases in CD4+ cell counts during antiretroviral therapy
    • Koletar SL, Williams PL, Wu J, et al.: Long-term follow-up of HIV-infected individuals who have significant increases in CD4+ cell counts during antiretroviral therapy. Clin Infect Dis 2004;39:1500-1506.
    • (2004) Clin Infect Dis , vol.39 , pp. 1500-1506
    • Koletar, S.L.1    Williams, P.L.2    Wu, J.3
  • 4
    • 29244449843 scopus 로고    scopus 로고
    • Virological control during the first 6-18 months after initiating highly active antiretroviral therapy as a predictor for outcome in HIVinfected patients: A Danish, population-based, 6-year follow-up study
    • Lohse N, Kronborg G, Gerstoft J, et al.: Virological control during the first 6-18 months after initiating highly active antiretroviral therapy as a predictor for outcome in HIVinfected patients: A Danish, population-based, 6-year follow-up study. Clin Infect Dis 2006;42:136-144.
    • (2006) Clin Infect Dis , vol.42 , pp. 136-144
    • Lohse, N.1    Kronborg, G.2    Gerstoft, J.3
  • 5
    • 21844462147 scopus 로고    scopus 로고
    • Multiple drug classwide resistance associated with poorer survival after treatment failure in a cohort of HIV-infected patients
    • Zaccarelli M, Tozzi V, Lorenzini P, et al.: Multiple drug classwide resistance associated with poorer survival after treatment failure in a cohort of HIV-infected patients. AIDS 2005;19:1081-1089.
    • (2005) AIDS , vol.19 , pp. 1081-1089
    • Zaccarelli, M.1    Tozzi, V.2    Lorenzini, P.3
  • 6
    • 58149519978 scopus 로고    scopus 로고
    • HIV-1 susceptibility to the maturation inhibitor bevirimat is modulated by natural polymorphisms at positions 369-371 in Gag spacer peptide 1
    • Baelen KV: HIV-1 susceptibility to the maturation inhibitor bevirimat is modulated by natural polymorphisms at positions 369-371 in Gag spacer peptide 1. Antiviral Ther 2008; 13:A30.
    • (2008) Antiviral Ther , vol.13
    • Baelen, K.V.1
  • 7
    • 14844357223 scopus 로고    scopus 로고
    • Analysis of full-length human immunodeficiency virus type 1 genome reveals a variable spectrum of subtypes B and F recombinants in Sao Paulo, Brazil
    • Sá-Filho DJS, Diaz RS, Munerato P, Brunstein A, Fusuma E, et al.: Analysis of full-length human immunodeficiency virus type 1 genome reveals a variable spectrum of subtypes B and F recombinants in Sao Paulo, Brazil. AIDS Res Hum Retroviruses 2005;21:145-151.
    • (2005) AIDS Res Hum Retroviruses , vol.21 , pp. 145-151
    • Sá-Filho, D.J.S.1    Diaz, R.S.2    Munerato, P.3    Brunstein, A.4    Fusuma, E.5
  • 9
    • 33750246313 scopus 로고    scopus 로고
    • Characterization of a new circulating recombinant form comprising HIV-1 subtypes C and B in southern Brazil
    • Santos AF, Sousa TM, Soares EA, et al.: Characterization of a new circulating recombinant form comprising HIV-1 subtypes C and B in southern Brazil. AIDS 2006;20:2011-2019.
    • (2006) AIDS , vol.20 , pp. 2011-2019
    • Santos, A.F.1    Sousa, T.M.2    Soares, E.A.3
  • 10
    • 54549093554 scopus 로고    scopus 로고
    • Selective regimes and evolutionary rates of HIV-1 subtype B V3 variants in the Brazilian epidemic
    • Diaz RS, Sanabani S, Sucupira MCA, Tanuri A, Sabino EC, and Janini LMR: Selective regimes and evolutionary rates of HIV-1 subtype B V3 variants in the Brazilian epidemic. Virology 2008;381:184-193.
    • (2008) Virology , vol.381 , pp. 184-193
    • Diaz, R.S.1    Sanabani, S.2    Sucupira, M.C.A.3    Tanuri, A.4    Sabino, E.C.5    Janini, L.M.R.6
  • 11
    • 0041421014 scopus 로고    scopus 로고
    • Estimating the length of the first antiretroviral therapy regiment durability in Sao Paulo, Brazil
    • Medeiros R and Castelo A: Estimating the length of the first antiretroviral therapy regiment durability in Sao Paulo, Brazil. Braz J Infect Dis 2002;6:298-304.
    • (2002) Braz J Infect Dis , vol.6 , pp. 298-304
    • Medeiros, R.1    Castelo, A.2
  • 13
    • 0037119035 scopus 로고    scopus 로고
    • Variability of critical epitopes within HIV-1 heptad repeat domains for selected entry inhibitors in HIV-infected populations worldwide [corrected]
    • Hanna SL, Yang C, Owen SM, and Lal RB: Variability of critical epitopes within HIV-1 heptad repeat domains for selected entry inhibitors in HIV-infected populations worldwide [corrected]. AIDS 2002;16:1603-1608.
    • (2002) AIDS , vol.16 , pp. 1603-1608
    • Hanna, S.L.1    Yang, C.2    Owen, S.M.3    Lal, R.B.4
  • 14
    • 0019296687 scopus 로고
    • A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences
    • Kimura M: A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. J Mol Evol 1980;16:111-120.
    • (1980) J Mol Evol , vol.16 , pp. 111-120
    • Kimura, M.1
  • 15
    • 34547781750 scopus 로고    scopus 로고
    • MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0
    • Tamura K, Dudley J, Nei M, and Kumar S: MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 2007;24:1596-1599.
    • (2007) Mol Biol Evol , vol.24 , pp. 1596-1599
    • Tamura, K.1    Dudley, J.2    Nei, M.3    Kumar, S.4
  • 16
    • 4344685387 scopus 로고    scopus 로고
    • Genotype and phenotype patterns of human immunodeficiency virus type 1 resistance to enfuvirtide during long-term treatment
    • Menzo S, Castagna A, Monachetti A, et al.: Genotype and phenotype patterns of human immunodeficiency virus type 1 resistance to enfuvirtide during long-term treatment. Antimicrob Agents Chemother 2004;48:3253-3259.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3253-3259
    • Menzo, S.1    Castagna, A.2    Monachetti, A.3
  • 17
    • 0031883832 scopus 로고    scopus 로고
    • Determinants of human immunodeficiency virus type 1 resistance to gp41- derived inhibitory peptides
    • Rimsky LT, Shugars DC, and Matthews TJ: Determinants of human immunodeficiency virus type 1 resistance to gp41- derived inhibitory peptides. J Virol 1998;72:986-993.
    • (1998) J Virol , vol.72 , pp. 986-993
    • Rimsky, L.T.1    Shugars, D.C.2    Matthews, T.J.3
  • 18
    • 48449083017 scopus 로고    scopus 로고
    • HIV-1 drug resistance mutations: An updated framework for the second decade of HAART
    • Shafer RW and Schapiro JM: HIV-1 drug resistance mutations: An updated framework for the second decade of HAART. AIDS Rev 2008;10:67-84.
    • (2008) AIDS Rev , vol.10 , pp. 67-84
    • Shafer, R.W.1    Schapiro, J.M.2
  • 19
    • 20044371998 scopus 로고    scopus 로고
    • Emergence and evolution of enfuvirtide resistance following long-term therapy involves heptad repeat 2 mutations within gp41
    • Xu L, Pozniak A, Wildfire A, et al.: Emergence and evolution of enfuvirtide resistance following long-term therapy involves heptad repeat 2 mutations within gp41. Antimicrob Agents Chemother 2005;49:1113-1119.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 1113-1119
    • Xu, L.1    Pozniak, A.2    Wildfire, A.3
  • 20
    • 4444310448 scopus 로고    scopus 로고
    • Characterization of determinants of genotypic and phenotypic resistance to enfuvirtide in baseline and on-treatment HIV-1 isolates
    • Sista PR, Melby T, Davison D, et al.: Characterization of determinants of genotypic and phenotypic resistance to enfuvirtide in baseline and on-treatment HIV-1 isolates. AIDS 2004;18:1787-1794.
    • (2004) AIDS , vol.18 , pp. 1787-1794
    • Sista, P.R.1    Melby, T.2    Davison, D.3
  • 21
    • 31144436790 scopus 로고    scopus 로고
    • Long-term monitoring of genotypic and phenotypic resistance to T20 in treated patients infected with HIV-1
    • Perez-Alvarez L, Carmona R, Ocampo A, et al.: Long-term monitoring of genotypic and phenotypic resistance to T20 in treated patients infected with HIV-1. J Med Virol 2006;78: 141-147.
    • (2006) J Med Virol , vol.78 , pp. 141-147
    • Perez-Alvarez, L.1    Carmona, R.2    Ocampo, A.3
  • 22
    • 33846029516 scopus 로고    scopus 로고
    • Increased polymorphism in the HR-1 gp41 env gene encoding the enfuvirtide (T-20) target in HIV-1 variants harboring multiple antiretroviral drug resistance mutations in the pol gene
    • Si-Mohamed A, Piketty C, Tisserand P, et al.: Increased polymorphism in the HR-1 gp41 env gene encoding the enfuvirtide (T-20) target in HIV-1 variants harboring multiple antiretroviral drug resistance mutations in the pol gene. J Acquir Immune Defic Syndr 2007;44:1-5.
    • (2007) J Acquir Immune Defic Syndr , vol.44 , pp. 1-5
    • Si-Mohamed, A.1    Piketty, C.2    Tisserand, P.3
  • 23
    • 0031729823 scopus 로고    scopus 로고
    • Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
    • Kilby JM, Hopkins S, Venetta TM, et al.: Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nat Med 1998;4: 1302-1307.
    • (1998) Nat Med , vol.4 , pp. 1302-1307
    • Kilby, J.M.1    Hopkins, S.2    Venetta, T.M.3
  • 24
    • 33748115445 scopus 로고    scopus 로고
    • Rapid emergence of enfuvirtide resistance in HIV-1-infected patients: Results of a clonal analysis
    • Lu J, Deeks SG, Hoh R, et al.: Rapid emergence of enfuvirtide resistance in HIV-1-infected patients: Results of a clonal analysis. J Acquir Immune Defic Syndr 2006;43:60-64.
    • (2006) J Acquir Immune Defic Syndr , vol.43 , pp. 60-64
    • Lu, J.1    Deeks, S.G.2    Hoh, R.3
  • 25
    • 39549102404 scopus 로고    scopus 로고
    • Adherence to enfuvirtide and its impact on treatment efficacy
    • Rockstroh J, Dejesus E, Donatacci L, et al.: Adherence to enfuvirtide and its impact on treatment efficacy. AIDS Res Hum Retroviruses 2008;24:141-148.
    • (2008) AIDS Res Hum Retroviruses , vol.24 , pp. 141-148
    • Rockstroh, J.1    Dejesus, E.2    Donatacci, L.3
  • 26
    • 60849084600 scopus 로고    scopus 로고
    • Enfuvirtide (T-20) resistance-related mutations in HIV type 1 subtypes B, C, and F isolates from Brazilian patients failing HAART
    • Oliveira AC, Martins AN, Pires AF, et al.: Enfuvirtide (T-20) resistance-related mutations in HIV type 1 subtypes B, C, and F isolates from Brazilian patients failing HAART. AIDS Res Hum Retroviruses 2009;25:193-198.
    • (2009) AIDS Res Hum Retroviruses , vol.25 , pp. 193-198
    • Oliveira, A.C.1    Martins, A.N.2    Pires, A.F.3
  • 27
    • 0038576281 scopus 로고    scopus 로고
    • Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America
    • Lalezari JP, Henry K, O'HearnM, et al.: Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America. N Engl J Med 2003;348:2175-2185.
    • (2003) N Engl J Med , vol.348 , pp. 2175-2185
    • Lalezari, J.P.1    O'Hearnm, H.K.2
  • 28
    • 0037849954 scopus 로고    scopus 로고
    • Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia
    • Lazzarin A, Clotet B, Cooper D, et al.: Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia. N Engl J Med 2003;348:2186-2195.
    • (2003) N Engl J Med , vol.348 , pp. 2186-2195
    • Lazzarin, A.1    Clotet, B.2    Cooper, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.