Evaluation of 4′,6-diamidino-2-phenylindole as a fluorescent probe substrate for rapid assays of the functionality of human multidrug and toxin extrusion proteins

Drug Metabolism and Disposition

Volumn 38, Issue 4, 2010, Pages 715-721

  Yasujima, Tomoya ^a   Ohta, Kin Ya ^a   Inoue, Katsuhisa ^a   Ishimaru, Munenori ^b   Yuasa, Hiroaki ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b AICHI GAKUIN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 4 AMINOHIPPURIC ACID; 4',6 DIAMIDINO 2 PHENYLINDOLE; ANTIPORTER; CIMETIDINE; CLONIDINE; COCARBOXYLASE; CORTICOSTERONE; DILTIAZEM; DIPHENHYDRAMINE; FLUORESCENT DYE; IMIPRAMINE; MULTIDRUG AND TOXIN EXTRUSION PROTEIN 1; MULTIDRUG AND TOXIN EXTRUSION PROTEIN 2 K; N METHYLNICOTINAMIDE; NICOTINAMIDE; NORADRENALIN; ORGANIC CATION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 2; ORGANIC CATION TRANSPORTER 3; PROCAINAMIDE; PROTEIN INHIBITOR; SEROTONIN; UNCLASSIFIED DRUG; VERAPAMIL; CARRIER PROTEIN; CATION; COMPLEMENTARY DNA; HISTAMINE H2 RECEPTOR ANTAGONIST; INDOLE DERIVATIVE; MATE1 PROTEIN, HUMAN; MATE2 K PROTEIN, HUMAN; MATE2-K PROTEIN, HUMAN; OCTAMER TRANSCRIPTION FACTOR 4; ORGANIC CATION TRANSPORTER; POU5F1 PROTEIN, HUMAN; RNA; SLC22A2 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FLUORESCENCE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; MICHAELIS CONSTANT; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; CELL LINE; DOG; GENETICS; KIDNEY; METABOLISM;

ANIMALS; CARRIER PROTEINS; CATIONS; CELL LINE; CIMETIDINE; DNA, COMPLEMENTARY; DOGS; FLUORESCENT DYES; HISTAMINE H2 ANTAGONISTS; HUMANS; INDOLES; KIDNEY; MICROSCOPY, FLUORESCENCE; OCTAMER TRANSCRIPTION FACTOR-3; ORGANIC CATION TRANSPORT PROTEINS; ORGANIC CATION TRANSPORTER 1; RNA;

EID: 77950199210     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.109.030221     Document Type: Article

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