Effect of fluid shear stress on tubular kidney epithelial cell structure

IFMBE Proceedings

Volumn 25, Issue 10, 2009, Pages 50-52

  Condorelli, L ^a   Cattaneo, I ^a   Arrigoni, C ^a   Antiga, L ^a   Perico, N ^a   Remuzzi, A ^a,b  

^a MARIO NEGRI INST PHARMACOL RES   (Italy)

^b UNIVERSITY OF BERGAMO   (Italy)

Author keywords

Cell structure; Epithelial cells; Fluid shear stress; Polycystic kidney disease

Indexed keywords

ARTIFICIAL ORGANS; CALCIUM; CELL CULTURE; CHELATION; DOMES; MEDICAL PHYSICS; MONOLAYERS; PARALLEL FLOW; PLATES (STRUCTURAL COMPONENTS); SCANNING ELECTRON MICROSCOPY; SHEAR FLOW; SHEAR STRESS; TISSUE; TISSUE ENGINEERING;

CELL STRUCTURE; CHELATING AGENT; EPITHELIAL CELLS; FLUID SHEAR STRESS; KIDNEY EPITHELIAL CELL; PARALLEL PLATE FLOW CHAMBER; POLYCYSTIC KIDNEY DISEASE; TUBULAR STRUCTURES;

CELLS;

EID: 77950185369     PISSN: 16800737     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1007/978-3-642-03900-3_15     Document Type: Conference Paper

References (7)

1. Nauli1 SM, Alenghat FJ, Luo Y et al. (2003) Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Gen 33:129-37.
2. Nauli SM, Rossetti S, Kolb RJ et al. (2007) Loss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction. JASN 17: 1015-25.
3. Loghman-Adham M, Nauli SM, Soto CE et al. (2003) Immortalized epithelial cells from human autosomal dominant polycystic kidney cysts. AJP 2003 285:F397-412.
4. Imberti B, Morigi M, Zoja C, et al. (2000) Shear stress-induced cyto-skeleton rearrangement mediates NF-kappaB-dependent endothelial expression of ICAM-1. Microvasc Res 60:182-8.
5. Morigi M, Galbusera M, Binda, E et al. (2001) Verotoxin-1-induced up-regulation of adhesive molecules renders microvascular endothelial cells thrombogenic at high shear stress. Blood 98:1828-35.
6. Praetorius, HA, Spring, KR. (2003) The renal cell primary cilium functions as a flow sensor Cur Opinion Nephr Hypert 12:517-520.
7. Praetorius, HA, Spring, KR. (2003) Bending the primary cilium opens Ca2+-sensitive intermediate-conductance K+ Channels in MDCK cells. J Mem Biol 191:193-200.