Antibiotic resistance patterns in gram-negative and gram-positive bacteria causing septicemia in newborns in León, Nicaragua: Correlation with environmental samples

Journal of Chemotherapy

Volumn 22, Issue 1, 2010, Pages 25-29

  Amaya, E ^a,b   Caceres, M ^b   Fang, H ^a   Torres Ramirez, A ^b   Palmgren, A C ^a   Nord, Carl Erik ^a   Weintraub, A ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b en el Jardín botánico ambiental de la UNAN León   (Nicaragua)

Author keywords

Antibiotic resistance; Neonatal septicemia; Nicaragua

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMOXICILLIN PLUS CLAVULANIC ACID; BETA LACTAM ANTIBIOTIC; CEFOXITIN; CEFTAZIDIME; CEFTRIAXONE; CIPROFLOXACIN; COTRIMOXAZOLE; ERYTHROMYCIN; EXTENDED SPECTRUM BETA LACTAMASE; GENTAMICIN; IMIPENEM; OXACILLIN; PENICILLIN G; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM IDENTIFICATION; CLONAL VARIATION; ENTEROBACTER CLOACAE; ENVIRONMENTAL FACTOR; ESCHERICHIA COLI; FEMALE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; NEWBORN; NEWBORN INTENSIVE CARE; NEWBORN MORTALITY; NEWBORN SEPSIS; NICARAGUA; NONHUMAN; PHENOTYPE; RANDOM AMPLIFIED POLYMORPHIC DNA; SERRATIA LIQUEFACIENS; STAPHYLOCOCCUS EPIDERMIDIS;

BACTEREMIA; BETA-LACTAMASES; DRUG RESISTANCE, BACTERIAL; FEMALE; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; INFANT, NEWBORN; INTENSIVE CARE UNITS, NEONATAL; MALE; MICROBIAL SENSITIVITY TESTS; NICARAGUA; POLYMERASE CHAIN REACTION; RISK FACTORS;

EID: 77950119535     PISSN: 1120009X     EISSN: 19739478     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Zaidi AK, Huskins WC, Thaver D, Bhutta ZA, Abbas Z, Goldmann DA. Hospital-acquired neonatal infections in developing countries. Lance 2005; 365(9465):1175-1188.
2. PAHO. Health situation analysts and trends summary of Nicaragua. [cited 2009; Analysis by population group children (0-4 years)]. Available from: http://www.paho.org/English/DD/AIS/cp-558.htm
3. WHO. Mortality country fact sheet 2006. [cted 2009; Causes of death in children under-5]. Available from: http://www.who.int/whosis/mort/profiles/mort- amro-nic-nicaragua.pdf
4. Carey AJ, Saiman L, Polin RA. Hospital-acquired infections in the NICU: epidemiology for the new millennium. Clin Perinatol 2008; 35(1):223-249.
5. Zingg W, Posfay-Barbe KM, Pittet D. Healthcare-associated infections in neonates. Curr Opin Infect Dis 2008; 21(3):228-234.
6. Stonati M, Borghesi A, Decembrino L, Bollani L. Antibiotics in neonatal intensive care units (NICUs). J Chemother 2007; 19 (2):52-55.
7. Fanos V, Cuzzolin L, Atzei A, Testa M. Antibiotics and antifungals in neonatal intensive care units: a review. J Chemother 2007; 19(1):5-20.
8. Curtis C, Shetty N. Recent trends and prevention of infection in the neonatal intensive care unit. Curr Opin Infect Dis 2008; 21(4):350-356.
9. Srivastava S, Shetty N. Healthcare-associated infections in neonatal units: lessons from contrasting worlds. J Hosp Infect 2007; 65(4)292-306.
10. Bizzarro MJ, Gallagher PG. Antibiotic-resistant organisms in the neonatal intensive care unit. Semin Perinatol 2007; 31(1)26-32.
11. Okeke IN, Laxminarayan R, Bhutta ZA, Duse AG, Jenkins P, O'Brien TF, et al. Antimicrobial resistance in developing countries. Part I: recent trends and current status. Lancet Infect Dis 2005; 5(8):481-493.
12. WHO. Pocket book of hospital care for children: guidelines for the management of common illnesses with limited resources. Geneva: 2005.
13. WHO. Serious childhood problems in countries with limited resources. Background book on management of the child with a serious infection or severe malnutrition. Geneva: Department of child and adolescent heelth and development 2004.
14. Lawn JE, Osrin D, Adler A. Cousens S. Four million neonatal deaths: counting and attribution of cause of death. Paediatr Perinat Epidemiol 2008; 22(5):410-416.
15. Sehulster L, Chien R, CDC, HICPAC. Guidelines for environmental infection control in health-care facilities. Recommendations of CDC and the healthcare infeclion control practices advisory committee (HICPAC). MMWR Recomm Rep 2003; 52(RR-10):1-42.
16. CLSI. Performance standards for antimicrobial disk susceptibility tests; Approved standard-ninth edition. CLSI: 2006.
17. CLSI. Methods for dilution antimicrobial susceptibility tests for bacterial that grow aerobically; Approved standard M7-A7-Seventh edition. M7-A7 Wayne, PA: CLSI; 2006.
18. Fang H, Ataker F, Hedin G, Dembusch K. Molecular epidemiology of extended-spectrum beta-lactamases among Escherichia coli isolates collected in a Swedish hospital and its associated health care facilities from 2001 to 2006. J Clin Microbiol 2008; 46(2):707-712.
19. Touati A, Benallaoua S, Djoudi F, Madoux J, Brasme L, De Champs C. Characterization of CTX-M-15-producing Klebsiella pneumoniae and Escherichia coli strains isolated from hospital environments in Algeria. Microb Drug Resist 2007; 13(2):85-89.
20. Amaya E, Caceres M, Fang H, Ramirez AT, Palmgren AC, Nord CE, at al. Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a neonatal intensive cate unit in Leon, Nicaragua. Int J Antimicrob Agents 2009; 33(4):386-387.
21. Zaidi AK, Thaver D, Ali SA, Khan TA. Pathogens associated with sepsis in newborns and young infants in developing countries. Pediatr Infect Dis J 2009; 28(1):S10-18.
22. Sehgal R, Gaind R, Chellani H, Agarwal P. Extended-spectrum beta-lactamase-producing gram-negative bacteria: clinical profile end outcome in a neonatal intensive care unit. Ann Trop Paediatr 2007; 27:45-54.
23. Perez F, Endimiani A, Hufer KM, Bocomo RA. The continuing challenge of ESBLs. Curr Opin Pharmacol 2007; 7(5):459-469.
24. Abdel-Hady H, Hawas S, El-Daker M, El-Kady R. Extended-spectrum beta-lactamase producing Klebsiella pneumoniae in neonatal intensive care unit. J Parinatol 2008; 28(10):685-690.
25. Venkatesh MP, Placencia F, Waisman LE. Coagulase-negative staphylococcal infections in the neonate and child: an update. Semin Pediatr Infect Dis 2006 17(3):120-127.
26. Waters V, Larson E, Wu F, San Gabriel P, Haas J, Cimiotti J, et al. Molecular epidemiology of Gram-negative bacilli from infected neonates and health care workers' hands in neonatal intensive care units. Clin Infect Dis 2004; 38(12):1682-1687.
27. Falagas ME, Bliziotis IA. Pandrug-resistant Gram-negative bacteria: the dawn of the post-antibiotic era? Int J Antimicrob Agents 2007; 29(6):630-636.
28. Talbot G, Bradley J, Edwards JJ, Gilbert D, Scheld M, Bartlett J. Bad bugs need drugs: an update on the development pipeline from the antimicrobial availability task force of the infectious diseases society of America. Clin Infect Dis 2006; 42(5):657-668.
29. Gould IM. The epidemiology of antibiotic resistance. Int J Antimicrob Agents 2008; 32(1):S2-9.
30. Hawkey PM, Jones AM. The changing epidemiology of resistance. J Antimicrob Chemother 2009; 64(1):i3-10.
31. Hawkey PM. The growing burden of antimicrobial resistance. J Antimicrob Chemother 2008; 62(1):i1-9.