(-)-Carbodine: Enantiomeric synthesis and in vitro antiviral activity against various strains of influenza virus including H5N1 (avian influenza) and novel 2009 H1N1 (swine flu)

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 8, 2010, Pages 2601-2604

  Rao, Jagadeeshwar R ^a   Jha, Ashok K ^a   Rawal, Ravindra K ^a   Sharon, Ashoke ^a   Day, Craig W ^b   Barnard, Dale L ^b   Smee, Donald F ^b   Chu, Chung K ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b UTAH STATE UNIVERSITY   (United States)

Author keywords

Anti influenza activity; Carbocyclic nucleosides; Carbodine

Indexed keywords

CARBODINE; RIBAVIRIN; RIBOSE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; AVIAN INFLUENZA; CELL STRAIN; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; ENANTIOSELECTIVITY; IC 50; INFLUENZA; INFLUENZA VIRUS A; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H5N1; INFLUENZA VIRUS B; NONHUMAN; REACTION ANALYSIS; STRUCTURE ANALYSIS; SWINE INFLUENZA; VIRUS STRAIN;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CYTIDINE; DOGS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; SERIAL PASSAGE; STEREOISOMERISM;

AVES; CERCOPITHECINE HERPESVIRUS 1; ORTHOMYXOVIRIDAE; SUIDAE;

EID: 77950062509     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.02.074     Document Type: Article

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