Cyclic stretch enhances the expression of Toll-like Receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase and NF-κB pathway

Journal of Biomedical Science

Volumn 17, Issue 1, 2010, Pages

  Shyu, Kou Gi ^a,b   Wang, Bao Wei ^c   Lin, Chiu Mei ^a   Chang, Hang ^a  

^a SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANGIOTENSIN II; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; DEOXYRIBONUCLEOPROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LOSARTAN; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCLONAL ANTIBODY; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL STRESS; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; HEART CELL CULTURE; HEART MUSCLE CELL; MECHANICAL STRESS; MONOCYTE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR GENE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOLL LIKE RECEPTOR 4 GENE; WESTERN BLOTTING; WISTAR RAT; ANIMAL; GENETICS; METABOLISM; UPREGULATION;

RATTUS; RATTUS NORVEGICUS;

ANIMALS; ANIMALS, NEWBORN; CELL ADHESION; MYOCYTES, CARDIAC; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

EID: 77949983956     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-17-15     Document Type: Article

References (27)

1. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. R Medzhitov P Preston-Hurlburt CA Janeway, Nature 1997 388 394 397 10.1038/41131 9237759
2. Cytokines link Toll-like receptor 4 signaling to cardiac dysfunction after global myocardial ischemia. J Cha Z Wang L Ao N Zou CA Dinarello A Banerjee DA Fullerton X Meng, Ann Thorac Surg 2008 85 1678 1685 10.1016/j.athoracsur.2008.01.043 18442564
3. Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium. S Frantz L Kobzik YD Kim R Fukazawa R Medzhitov RT Lee RA Kelly, J Clin Invest 1999 104 271 280 10.1172/JCI6709 10430608
4. Toll-like receptor stimulation in cardiomyocytes decreases contractility and initiates an NF-kappaB dependent inflammatory response. JH Boyd S Mathur Y Wang RM Bateman ER Walley, Cardiovasc Res 2006 72 384 393 10.1016/j.cardiores. 2006.09.011 17054926
5. Reduced myocardial ischemia-reperfusion injury in toll-like 4-deficient mice. J Oyama C Blais jr X Liu M Pu L Kobzik RA Kelly T Bourcier, Circulation 2004 109 784 789 10.1161/01.CIR.0000112575.66565.84 14970116
6. Is there a role for cardiomyocyte toll-like receptor 4 in endotoxemia? A Samantha SA Tavener P Kubes, Trends Cardiovasc Med 2005 15 153 157 10.1016/j.tcm.2005.06.001 16165010
7. Immune cell toll-like receptor 4 is required for cardiac myocyte impairment during endotoxemia. SA Tavener EM Long SM Robbins KM McRae H Van Remmen P Kubes, Circ Res 2004 95 700 707 10.1161/01.RES.0000144175.70140.8c 15358664
8. Reduced cardiac hypertrophy in toll-like receptor 4-deficient mice following pressure overload. T Ha Y Li F Hua J Ma X Gao J Kelley A Zhao GE Haddad DL Williams IW Browder RL Kao C Li, Cardiovasc Res 2005 68 224 234 10.1016/j.cardiores.2005.05.025 15967420
9. Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice. A Raid S Bien M Gratz F Escher D Westermann MM Heimesaat S Bereswill T Krieg SB Felix HP Schultheiss HK Kroemer C Tschope, Eur J Heart Fail 2008 10 233 243 10.1016/j.ejheart.2008.01.004 18321777
10. LPS-induced TNF-alpha release from and apoptosis in rat cardiomyocytes: obligatory role for CD14 in mediating the LPS response. KL Comstock KA Krown MT Page D Martin P Ho M Pedraza EN Castro N Nakajima CC Glembotski PJ Quintana RA Sabbadini, J Mol Cell Cardiol 1998 30 2761 2775 10.1006/jmcc.1998.0851 9990546
11. Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression. G Wright IS Singh JD Hasday IK Farrance G Hall AS Cross TB Rogers, Am J Physiol Heart Circ Physiol 2002 282 872 H879 11834481
12. Inflammatory mediators in chronic heart failure: an overview. SD Anker Haehling van, Heart 2004 90 464 470 10.1136/hrt.2002.007005 15020532
13. Innate immunity and inflammation - new frontiers in comparative cardiovascular pathology. A Linde D Mosier F Blecha T Melgarejo, Cardiovasc Res 2007 73 26 36 10.1016/j.cardiores.2006.08.009 17010957
14. Roles of intercellular adhesion molecule-1 in hypertensive cardiac remodeling. F Kuwahara H Kai K Tokuda H Niiyama N Tahara K Kusaba K Takemiya A Jalalidin M Koga T Nagata R Shibata T Imaizumi, Hypertension 2003 41 819 823 10.1161/01.HYP.0000056108.73219.0A 12624002
15. Cyclical mechanical stretch enhances angiopoietin-2 and Tie2 receptor expression in cultured human umbilical vein endothelial cells. H Chang BW Wang P Kuan KG Shyu, Clin Sci 2003 104 421 428 10.1042/CS20020210 12653688
16. Regulation of discoidin domain receptor 2 by cyclic mechanical stretch in cultured rat vascular smooth muscle cells. KG Shyu YM Chao BW Wang P Kuan, Hypertension 2005 46 614 621 10.1161/01.HYP.0000175811.79863.e2 16087782
17. Angiotensin II receptor antagonist blocks the expression of connexin43 induced by cyclical mechanical stretch in cultured neonatal rat cardiac myocytes. KG Shyu CC Chen BW Wang PL Kuan, J Mol Cell Cardiol 2001 33 691 698 10.1006/jmcc.2000.1333 11273722
18. The role of toll-like receptors in the regulation of neutrophil migration, activation, and apoptosis. I Sabroe SK Dower MKB Whyte, Clin Infect Dis 2005 41 421 S426 10.1086/431992 16237641
19. Activated macrophages decrease rat cardiac myocyte contractility: importance of ICAM-1-dependnet adhesion. MG Simms KR Walley, Am J Physiol Heart Circ Physiol 1999 277 253 H260
20. Cellular and molecular mechanisms underlying LPS-associated myocyte impairement. S Tavener P Kubes, Am J Physiol Heart Circ Physiol 2006 290 800 H806 10.1152/ajpheart.00701.2005 16172157
21. Protection against myoocardial ischemia/reperfusion injury in TLR4-deficient mice is mediated through a phosphoinostide 3-kinase-dependent mechanism. F Hua T Ha J Ma Y Li J Kelley X Gao IW Browder RL Kao DL Williams C Li, J Immunol 2007 178 7317 7324 17513782
22. Alteration in the cardiac inflammatory response to burn trauma in mice lacking a functiona; toll-like receptor 4 gene. B Bruns D Maass R Barber J Horton D Carison, Shock 2008 30 740 746 10.1097/SHK.0b013e318173f329 18496236
23. Cellular and molecular effects of mechanical stretch on vascular cells and cardiac myocytes. KG Shyu, Clin Sci 2009 116 377 389 10.1042/CS20080163 19175356
24. Angiotensin II upregulates toll-like receptor 4 on mesanginal cells. G Wolf J Bohlender T Bondeva T Roger F Thaiss UO Wenzel, J Am Soc Nephrol 2006 17 1585 1593 10.1681/ASN.2005070699 16675600
25. Toll-liker receptors in cardiovascular diseases. D De Kleijn G Pasterkamp, Cardiovasc Res 2003 60 58 67 10.1016/S0008-6363(03)00348-1 14522407
26. Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. JR Caso JM Pradillo O Hurtado P Lorenzo MA Moro I Lizasoain, Circulation 2007 115 1599 1608 10.1161/CIRCULATIONAHA.106.603431 17372179
27. Toll-like receptor-mediated NF-B activation: a phylogenetically conserved paradigm in innate immunity. G Zhang S Ghosh, J Clin Invest 2001 107 13 19 10.1172/JCI11837 11134172