Central representation of the inferior rectal nerve of the rat

Diseases of the Colon and Rectum

Volumn 53, Issue 3, 2010, Pages 315-320

  Peirce, Colin ^a   Alexander, Lauren E ^a   O'Herlihy, Colm ^a,b   O'Connell, P Ronan ^a,c   Jones, James F X ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b NATIONAL MATERNITY HOSPITAL   (Ireland)

^c ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

Author keywords

Animal model; Fecal incontinence; Inferior rectal nerve; Motoneuron; Rat; Sacral nerve stimulation; Sensory neuron

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; FLUOROGOLD; MOLECULAR MARKER;

ANIMAL EXPERIMENT; ANUS SPHINCTER; ARTICLE; ELECTROSTIMULATION; FECES INCONTINENCE; FEMALE; INTESTINE INNERVATION; LUMBOSACRAL SPINE; MOTONEURON; MOTOR NERVE; NONHUMAN; PUDENDAL NERVE; RAT; SENSORY NERVE; SENSORY NERVE CELL; SPINAL GANGLION; ANIMAL; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INNERVATION; RECTUM; SPINAL ROOT; STAINING; ULTRASTRUCTURE; WISTAR RAT;

ACTIVATING TRANSCRIPTION FACTOR 3; ANIMALS; FEMALE; IMMUNOHISTOCHEMISTRY; MOTOR NEURONS; RATS; RATS, WISTAR; RECTUM; SPINAL NERVE ROOTS; STAINING AND LABELING;

EID: 77949909127     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1007/DCR.0b013e3181c3873c     Document Type: Article

References (21)

1. Buckley BS, Lapitan MC. Prevalence of urinary and faecal incontinence and nocturnal enuresis and attitudes to treatment and help-seeking amongst a community-based representative sample of adults in the United Kingdom. Int J Clin Pract. 2009;263:568-573.
2. Nelson R, Norton N, Cautley E, Furner S. Community-based prevalence of anal incontinence. JAMA. 1995;274:559-561.
3. Whitehead WE. Diagnosing and managing fecal incontinence: if you don't ask they won't tell. Gastroenterology. 2005;129:6.
4. Snooks SJ, Henry MM, Swash M. Faecal incontinence due to external anal sphincter division in childbirth is associated with damage to the innervation of the pelvic floor musculature: a double pathology. Br J Obstet Gynaecol. 1985;92:824-828. (Pubitemid 16172052)
5. Fitzpatrick M, O'Brien C, O'Connell PR, O'Herlihy C. Patterns of abnormal pudendal nerve function associated with postpartum faecal incontinence. Am J Obstet Gynecol. 2003;189:730-735. (Pubitemid 37194095)
6. Matzel KE, Stadelmaier U, Hohenfellner M, Gall FP. Electrical stimulation of sacral spinal nerves for treatment of faecal incontinence. Lancet. 1995;346:1124-1127.
7. Melenhorst J, Koch SM, Uludag O, van Gemert WG, Baeten CG. Sacral neuromodulation in patients with faecal incontinence: results for the first 100 permanent implantations. Colorectal Dis. 2007;9:725-730. (Pubitemid 47422972)
8. O'Riordan JM, Healy CF, McLoughlin D, Cassidy M, Brannigan AE, O'Connell PR. Sacral nerve stimulation for faecal incontinence. Ir J Med Sci. 2008;177:117-119.
9. Koch S M P, van Gemert WG, Baeten CG. Determinationoftherapeutic threshold in sacral nerve modulation for faecal incontinence. Br J Surg. 2005;92:83-87. (Pubitemid 40144199)
10. Fowler CJ. The perspective of a neurologist on treatment-related research in fecal and urinary incontinence. Gastroenterology. 2004;126: S172-S174. (Pubitemid 38036861)
11. Fowler CJ, Swinn MJ, Goodwin RJ, Oliver S, Craggs M. Studies of the latency of pelvic floor contraction during peripheral nerve evaluation show that the muscle response is reflexly mediated. J Urol. 2000;163:881-883. (Pubitemid 30091638)
12. Healy CF, O'Herlihy C, O'Brien C, O'Connell PR, Jones JF. Experimental models of neuropathic fecal incontinence: an animal model of childbirth injury to the pudendal nerve and external anal sphincter. Dis Colon Rectum. 2008;51:1619-1626.
13. Peirce C, Healy CF, O'Herlihy C, O'Connell PR, Jones JF. Reduced somatosensory cortical activation in experimental models of neuropathic fecal incontinence. Dis Colon Rectum. 2009;52:1417-1422.
14. Molander C, Grant G. Spinal cord cytoarchitecture. Paxinos G. The Rat Nervous System. San Diego, CA: Academic Press; 1995.
15. McKenna KE, Nadelhaft I. The organisation of the pudendal nerve in the male and female rat. J Comp Neurol. 1986;248:532-549. (Pubitemid 16073029)
16. Tsujino H, Kondo E, Fukuoka T, et al. Activating transcription factor3 (ATF3) induction by axotomy insensory and motoneurons: a novel neuronal marker of nerve injury. Mol Cell Neurosci. 2000;15:170-182. (Pubitemid 30109120)
17. Kane DD, Shott S, Hughes WF, Kerns JM. Motor pudendal nerve characterization in the female rat. Anat Rec. 2002;266:21-29. (Pubitemid 34027832)
18. Holmes GM. 5-Hydroxytryptamine2C receptors on pudendal motoneurons innervating the external anal sphincter. Brain Res. 2005;1057:65-71. (Pubitemid 41338088)
19. Abercrombie M. Estimation of nuclear population from microtome sections. Anat Rec. 1946;94:239-247.
20. Harper AA, Lawson SN. Conduction velocity is related to morphological cell type in rat dorsal root ganglion neurones. J Physiol. 1985;359:31-46. (Pubitemid 15152926)
21. Hu P, McLachlan EM. Selective reactionsofcutaneous andmuscle afferent neurons to peripheral nerve transaction in rats. J Neurosci. 2003;23:10559-10567. (Pubitemid 37485269)