-
1
-
-
19444375104
-
DNA-based therapeutics and DNA delivery systems: A comprehensive review
-
Patil SD, Rhodes DG, Burgess DJ DNA-based therapeutics and DNA delivery systems: a comprehensive review. AAPS J. 2005 ; 7: E61 - E77.
-
(2005)
AAPS J
, vol.7
-
-
Patil, S.D.1
Rhodes, D.G.2
Burgess, D.J.3
-
2
-
-
0025074907
-
Vitro selection of RNA molecules that bind specific ligands
-
Ellington AD, Szostak JW In vitro selection of RNA molecules that bind specific ligands. Nature. 1990 ; 346: 818-822.
-
(1990)
Nature
, vol.346
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
3
-
-
0025194307
-
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
-
Tuerk C., Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science. 1990 ; 249: 505-510.
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
4
-
-
44649163943
-
Phase 1b randomized study of antidote-controlled modulation of factor IXa activity in patients with stable coronary artery disease
-
Chan MY, Cohen MG, Dyke CK, et al. Phase 1b randomized study of antidote-controlled modulation of factor IXa activity in patients with stable coronary artery disease. Circulation. 2008 b; 117: 2865-2874.
-
(2008)
Circulation
, vol.117
, pp. 2865-2874
-
-
Chan, M.Y.1
Cohen, M.G.2
Dyke, C.K.3
-
5
-
-
33747007916
-
Pegaptanib: A novel approach to ocular neovascularization
-
Chapman JA, Beckey C. Pegaptanib: a novel approach to ocular neovascularization. Ann Pharmacother. 2006 ; 40: 1322-1326.
-
(2006)
Ann Pharmacother
, vol.40
, pp. 1322-1326
-
-
Chapman, J.A.1
Beckey, C.2
-
6
-
-
46049096465
-
Molecular recognition of small-cell lung cancer cells using aptamers
-
Chen HW, Medley CD, Sefah K., et al. Molecular recognition of small-cell lung cancer cells using aptamers. ChemMedChem. 2008 ; 3: 991-1001.
-
(2008)
ChemMedChem
, vol.3
, pp. 991-1001
-
-
Chen, H.W.1
Medley, C.D.2
Sefah, K.3
-
7
-
-
42349091244
-
SsDNA aptamer-based surface plasmon resonance biosensor for the detection of retinol binding protein 4 for the early diagnosis of type 2 diabetes
-
Lee SJ, Youn BS, Park JW, Niazi JH, Kim YS, Gu MB ssDNA aptamer-based surface plasmon resonance biosensor for the detection of retinol binding protein 4 for the early diagnosis of type 2 diabetes. Anal Chem. 2008 ; 80: 2867-2873.
-
(2008)
Anal Chem
, vol.80
, pp. 2867-2873
-
-
Lee, S.J.1
Youn, B.S.2
Park, J.W.3
Niazi, J.H.4
Kim, Y.S.5
Gu, M.B.6
-
8
-
-
22544477581
-
Aptamers as tools for target validation
-
Blank M., Blind M. Aptamers as tools for target validation. Curr Opin Chem Biol. 2005 ; 9: 336-342.
-
(2005)
Curr Opin Chem Biol
, vol.9
, pp. 336-342
-
-
Blank, M.1
Blind, M.2
-
9
-
-
11144290107
-
Aptamers in research and drug development
-
Mayer G., Jenne A. Aptamers in research and drug development. BioDrugs. 2004 ; 18: 351-359.
-
(2004)
BioDrugs
, vol.18
, pp. 351-359
-
-
Mayer, G.1
Jenne, A.2
-
10
-
-
43949143533
-
Aptamer-modified monolithic capillary chromatography for protein separation and detection
-
Zhao Q., Li XF, Le XC Aptamer-modified monolithic capillary chromatography for protein separation and detection. Anal Chem. 2008 ; 80: 3915-3920.
-
(2008)
Anal Chem
, vol.80
, pp. 3915-3920
-
-
Zhao, Q.1
Li, X.F.2
Le, X.C.3
-
11
-
-
33644942097
-
An electronic, aptamer-based small-molecule sensor for the rapid, label-free detection of cocaine in adulterated samples and biological fluids
-
Baker BR, Lai RY, Wood MS, Doctor EH, Heeger AJ, Plaxco KW An electronic, aptamer-based small-molecule sensor for the rapid, label-free detection of cocaine in adulterated samples and biological fluids. J Am Chem Soc. 2006 ; 128: 3138-3139.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 3138-3139
-
-
Baker, B.R.1
Lai, R.Y.2
Wood, M.S.3
Doctor, E.H.4
Heeger, A.J.5
Plaxco, K.W.6
-
12
-
-
53849109617
-
A new aptameric biosensor for cocaine based on surface-enhanced Raman scattering spectroscopy
-
Chen J., Jiang J., Gao X., Liu G., Shen G., Yu R. A new aptameric biosensor for cocaine based on surface-enhanced Raman scattering spectroscopy. Chemistry. 2008 ; 14: 8374-8382.
-
(2008)
Chemistry
, vol.14
, pp. 8374-8382
-
-
Chen, J.1
Jiang, J.2
Gao, X.3
Liu, G.4
Shen, G.5
Yu, R.6
-
13
-
-
33748632129
-
Probing single-stranded DNA and its biomolecular interactions through direct catalytic activation of factor XII, a protease of the blood coagulation cascade
-
Pavlov V., Zorn M., Kramer R. Probing single-stranded DNA and its biomolecular interactions through direct catalytic activation of factor XII, a protease of the blood coagulation cascade. Biochem Biophys Res Commun. 2006 ; 349: 1011-1015.
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 1011-1015
-
-
Pavlov, V.1
Zorn, M.2
Kramer, R.3
-
14
-
-
34447322451
-
Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation
-
Kannemeier C., Shibamiya A., Nakazawa F., et al. Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation. Proc Natl Acad Sci U S A. 2007 ; 104: 6388-6393.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 6388-6393
-
-
Kannemeier, C.1
Shibamiya, A.2
Nakazawa, F.3
-
16
-
-
0026492431
-
The contact activation proteins: A structure/function overview
-
Meijers JC, Mcmullen BA, Bouma BN The contact activation proteins: a structure/function overview. Agents Actions Suppl. 1992 ; 38 (pt 2). 219-230.
-
(1992)
Agents Actions Suppl
, vol.38
, Issue.2
, pp. 219-230
-
-
Meijers, J.C.1
McMullen, B.A.2
Bouma, B.N.3
-
17
-
-
0036369436
-
Contact system. New concepts on activation mechanisms and bioregulatory functions
-
Mosc).
-
Yarovaya GA, Blokhina TB, Neshkova EA Contact system. New concepts on activation mechanisms and bioregulatory functions. Biochemistry (Mosc). 2002 ; 67: 13-24.
-
(2002)
Biochemistry
, vol.67
, pp. 13-24
-
-
Yarovaya, G.A.1
Blokhina, T.B.2
Neshkova, E.A.3
-
18
-
-
0034214874
-
Quality assessment of heparin coatings by their binding capacities of coagulation and complement enzymes
-
Weber N., Wendel HP, Ziemer G. Quality assessment of heparin coatings by their binding capacities of coagulation and complement enzymes. J Biomater Appl. 2000 ; 15: 8-22.
-
(2000)
J Biomater Appl
, vol.15
, pp. 8-22
-
-
Weber, N.1
Wendel, H.P.2
Ziemer, G.3
-
19
-
-
0036628791
-
Hemocompatibility of medical connectors with biopassive or bioactive surface coatings
-
Wendel HP, Hauser N., Briquet F., Ziemer G. Hemocompatibility of medical connectors with biopassive or bioactive surface coatings. J Biomater Appl. 2002 ; 17: 5-17.
-
(2002)
J Biomater Appl
, vol.17
, pp. 5-17
-
-
Wendel, H.P.1
Hauser, N.2
Briquet, F.3
Ziemer, G.4
-
20
-
-
33646448553
-
Tirofiban (Aggrastat) protects platelets and decreases platelet-granulocyte binding in an extracorporeal circulation model
-
Straub A., Azevedo R., Beierlein W., Wendel HP, Dietz K., Ziemer G. Tirofiban (Aggrastat) protects platelets and decreases platelet-granulocyte binding in an extracorporeal circulation model. Thorac Cardiovasc Surg. 2006 ; 54: 162-167.
-
(2006)
Thorac Cardiovasc Surg
, vol.54
, pp. 162-167
-
-
Straub, A.1
Azevedo, R.2
Beierlein, W.3
Wendel, H.P.4
Dietz, K.5
Ziemer, G.6
-
21
-
-
0026073646
-
Modified deoxyoligonucleotides stable to exonuclease degradation in serum
-
Shaw JP, Kent K., Bird J., Fishback J., Froehler B. Modified deoxyoligonucleotides stable to exonuclease degradation in serum. Nucleic Acids Res. 1991 ; 19: 747-750.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 747-750
-
-
Shaw, J.P.1
Kent, K.2
Bird, J.3
Fishback, J.4
Froehler, B.5
-
22
-
-
0019733067
-
Structural gene identification utilizing eukaryotic cell-free translational systems
-
Paterson BM, Roberts BE Structural gene identification utilizing eukaryotic cell-free translational systems. Gene Amplif Anal. 1981 ; 2: 417-437.
-
(1981)
Gene Amplif Anal
, vol.2
, pp. 417-437
-
-
Paterson, B.M.1
Roberts, B.E.2
-
23
-
-
35348911812
-
Brothers in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies
-
Bhindi R., Fahmy RG, Lowe HC, et al. Brothers in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies. Am J Pathol. 2007 ; 171: 1079-1088.
-
(2007)
Am J Pathol
, vol.171
, pp. 1079-1088
-
-
Bhindi, R.1
Fahmy, R.G.2
Lowe, H.C.3
-
24
-
-
0032004967
-
A good antisense molecule is hard to find
-
Branch AD A good antisense molecule is hard to find. Trends Biochem Sci. 1998 ; 23: 45-50.
-
(1998)
Trends Biochem Sci
, vol.23
, pp. 45-50
-
-
Branch, A.D.1
-
26
-
-
0028943759
-
Antigene, ribozyme and aptamer nucleic acid drugs: Progress and prospects
-
Stull RA, Szoka FC Jr. Antigene, ribozyme and aptamer nucleic acid drugs: progress and prospects. Pharm Res. 1995 ; 12: 465-483.
-
(1995)
Pharm Res
, vol.12
, pp. 465-483
-
-
Stull, R.A.1
-
27
-
-
34548262708
-
Pegaptanib 1-year systemic safety results from a safety-pharmacokinetic trial in patients with neovascular age-related macular degeneration
-
Apte RS, Modi M., Masonson H., Patel M., Whitfield L., Adamis AP Pegaptanib 1-year systemic safety results from a safety-pharmacokinetic trial in patients with neovascular age-related macular degeneration. Ophthalmology. 2007 ; 114: 1702-1712.
-
(2007)
Ophthalmology
, vol.114
, pp. 1702-1712
-
-
Apte, R.S.1
Modi, M.2
Masonson, H.3
Patel, M.4
Whitfield, L.5
Adamis, A.P.6
-
28
-
-
33748779821
-
Pegaptanib (Macugen): Treating neovascular age-related macular degeneration and current role in clinical practice
-
Vavvas D., DAmico DJ Pegaptanib (Macugen): treating neovascular age-related macular degeneration and current role in clinical practice. Ophthalmol Clin North Am. 2006 ; 19: 353-360.
-
(2006)
Ophthalmol Clin North Am
, vol.19
, pp. 353-360
-
-
Vavvas, D.1
Damico, D.J.2
-
29
-
-
37349040378
-
First-in-human evaluation of anti von Willebrand factor therapeutic aptamer ARC1779 in healthy volunteers
-
Gilbert JC, Feo-Fraulini T., Hutabarat RM, et al. First-in-human evaluation of anti von Willebrand factor therapeutic aptamer ARC1779 in healthy volunteers. Circulation. 2007 ; 116: 2678-2686.
-
(2007)
Circulation
, vol.116
, pp. 2678-2686
-
-
Gilbert, J.C.1
Feo-Fraulini, T.2
Hutabarat, R.M.3
-
30
-
-
8344221992
-
Antidote-mediated control of an anticoagulant aptamer in vivo
-
Rusconi CP, Roberts JD, Pitoc GA, et al. Antidote-mediated control of an anticoagulant aptamer in vivo. Nat Biotechnol. 2004 ; 22: 1423-1428.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1423-1428
-
-
Rusconi, C.P.1
Roberts, J.D.2
Pitoc, G.A.3
-
31
-
-
35148840942
-
Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy
-
Famulok M., Hartig JS, Mayer G. Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy. Chem Rev. 2007 ; 107: 3715-3743.
-
(2007)
Chem Rev
, vol.107
, pp. 3715-3743
-
-
Famulok, M.1
Hartig, J.S.2
Mayer, G.3
-
32
-
-
6344244639
-
Overview of target validation and the impact of oligonucleotides
-
Jones SW, Lindsay MA Overview of target validation and the impact of oligonucleotides. Curr Opin Mol Ther. 2004 ; 6: 546-550.
-
(2004)
Curr Opin Mol Ther
, vol.6
, pp. 546-550
-
-
Jones, S.W.1
Lindsay, M.A.2
-
33
-
-
33646255219
-
Liquid chromatography, electrochromatography and capillary electrophoresis applications of DNA and RNA aptamers
-
Ravelet C., Grosset C., Peyrin E. Liquid chromatography, electrochromatography and capillary electrophoresis applications of DNA and RNA aptamers. J Chromatogr A. 2006 ; 1117: 1-10.
-
(2006)
J Chromatogr A
, vol.1117
, pp. 1-10
-
-
Ravelet, C.1
Grosset, C.2
Peyrin, E.3
-
34
-
-
0037173068
-
Vivo properties of an anti-GnRH Spiegelmer: An example of an oligonucleotide-based therapeutic substance class
-
Wlotzka B., Leva S., Eschgfaller B., et al. In vivo properties of an anti-GnRH Spiegelmer: an example of an oligonucleotide-based therapeutic substance class. Proc Natl Acad Sci U S A. 2002 ; 99: 8898-8902.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 8898-8902
-
-
Wlotzka, B.1
Leva, S.2
Eschgfaller, B.3
-
35
-
-
0020021627
-
The biochemistry and pathophysiology of the contact system of plasma
-
Cochrane CG, Griffin JH The biochemistry and pathophysiology of the contact system of plasma. Adv Immunol. 1982 ; 33: 241-306.
-
(1982)
Adv Immunol
, vol.33
, pp. 241-306
-
-
Cochrane, C.G.1
Griffin, J.H.2
-
36
-
-
0022593032
-
The contact activation system: Biochemistry and interactions of these surface-mediated defense reactions
-
Colman RW, Schmaier AH The contact activation system: biochemistry and interactions of these surface-mediated defense reactions. Crit Rev Oncol Hematol. 1986 ; 5: 57-85.
-
(1986)
Crit Rev Oncol Hematol
, vol.5
, pp. 57-85
-
-
Colman, R.W.1
Schmaier, A.H.2
-
37
-
-
0030830360
-
Contact system: A vascular biology modulator with anticoagulant, profibrinolytic, antiadhesive, and proinflammatory attributes
-
Colman RW, Schmaier AH Contact system: a vascular biology modulator with anticoagulant, profibrinolytic, antiadhesive, and proinflammatory attributes. Blood. 1997 ; 90: 3819-3843.
-
(1997)
Blood
, vol.90
, pp. 3819-3843
-
-
Colman, R.W.1
Schmaier, A.H.2
-
38
-
-
0023624010
-
Initiation of blood coagulation at artificial surfaces
-
Colman RW, Scott CF, Schmaier AH, Wachtfogel YT, Pixley RA, Edmunds LH Jr. Initiation of blood coagulation at artificial surfaces. Ann N Y Acad Sci. 1987 ; 516: 253-267.
-
(1987)
Ann N y Acad Sci
, vol.516
, pp. 253-267
-
-
Colman, R.W.1
Scott, C.F.2
Schmaier, A.H.3
Wachtfogel, Y.T.4
Pixley, R.A.5
-
39
-
-
13444311776
-
Extracellular RNA is a natural cofactor for the (auto-)activation of factor VII-activating protease (FSAP)
-
Nakazawa F., Kannemeier C., Shibamiya A., et al. Extracellular RNA is a natural cofactor for the (auto-)activation of factor VII-activating protease (FSAP). Biochem J. 2005 ; 385: 831-838.
-
(2005)
Biochem J
, vol.385
, pp. 831-838
-
-
Nakazawa, F.1
Kannemeier, C.2
Shibamiya, A.3
-
40
-
-
0035128439
-
New anticoagulant drugs
-
Weitz JI, Hirsh J. New anticoagulant drugs. Chest. 2001 ; 119: 95S - 107S.
-
(2001)
Chest
, vol.119
-
-
Weitz, J.I.1
Hirsh, J.2
-
41
-
-
0021235057
-
Vitro activation of the contact (Hageman factor) system of plasma by heparin and chondroitin sulfate e
-
Hojima Y., Cochrane CG, Wiggins RC, Austen KF, Stevens RL In vitro activation of the contact (Hageman factor) system of plasma by heparin and chondroitin sulfate E. Blood. 1984 ; 63: 1453-1459.
-
(1984)
Blood
, vol.63
, pp. 1453-1459
-
-
Hojima, Y.1
Cochrane, C.G.2
Wiggins, R.C.3
Austen, K.F.4
Stevens, R.L.5
-
42
-
-
0014883076
-
Generation of kinin-like agents by chondroitin sulfate, heparin, chitin sulfate, and human articular cartilage: Possible pathophysiologic implications
-
Moskowitz RW, Schwartz HJ, Michel B., Ratnoff OD, Astrup T. Generation of kinin-like agents by chondroitin sulfate, heparin, chitin sulfate, and human articular cartilage: possible pathophysiologic implications. J Lab Clin Med. 1970 ; 76: 790-798.
-
(1970)
J Lab Clin Med
, vol.76
, pp. 790-798
-
-
Moskowitz, R.W.1
Schwartz, H.J.2
Michel, B.3
Ratnoff, O.D.4
Astrup, T.5
|