Hemoglobin-vesicle, a cellular artificial oxygen carrier that fulfils the physiological roles of the red blood cell structure

Advances in Experimental Medicine and Biology

Volumn 662, Issue , 2010, Pages 433-438

  Sakai, Hiromi ^a   Sou, Keitaro ^a   Horinouchi, Hirohisa ^a   Kobayashi, Koichi ^a   Tsuchida, Eishun ^a  

^a WASEDA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; HEMOGLOBIN; LIPOSOME; NITRIC OXIDE; OXYGEN;

CELL ENCAPSULATION; CELL FUNCTION; COLLOID; CONFERENCE PAPER; DIFFUSION; ERYTHROCYTE STRUCTURE; HEMOGLOBIN VESICLE; HEMORRHAGIC SHOCK; LIPID BILAYER; MEMBRANE VESICLE; NONHUMAN; OSMOTIC PRESSURE; OXYGEN TRANSPORT; PRIORITY JOURNAL; RESUSCITATION; VASCULARIZATION; CELL STRUCTURE; CYTOLOGY; ERYTHROCYTE; HUMAN; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW;

CELLULAR STRUCTURES; ERYTHROCYTES; HEMOGLOBINS; HUMANS; OXYGEN; SHOCK, HEMORRHAGIC;

EID: 77949898570     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-1241-1_62     Document Type: Conference Paper

References (12)

1. Sakai H, Sou K, Horinouchi H, Kobayashi K, Tsuchida E. (2008) Haemoglobin-vesicles as artificial oxygen carriers: present situation and future visions. J Intern Med 263:4-15. (Pubitemid 350243556)
2. Sakai H, Okamoto M, Ikeda E, Horinouchi H, Kobayashi K, Tsuchida E. (2009) J Biomed Mater Res A 90:1107-1119.
3. Sakai H, Tomiyama KI, Sou K, Takeoka S, Tsuchida E. (2000) Poly(ethylene glycol)- conjugation and deoxygenation enable long-term preservation of hemoglobin-vesicles as oxygen carriers in a liquid state. Bioconjug Chem 11:425-432 (Pubitemid 30324910)
4. Sakai H, Horinouchi H, Tomiyama K, Ikeda E, Takeoka S, Kobayashi K, Tsuchida E. (2001) Hemoglobin-vesicles as oxygen carriers: influence on phagocytic activity and histopathological changes in reticuloendothelial system. Am J Pathol 159:1079-1088. (Pubitemid 32847198)
5. Sakai H, Masada Y, Horinouchi H, Ikeda E, Sou K, Takeoka S, Suematsu M, Takaori M, Kobayashi K, Tsuchida E. (2004) Physiological capacity of the reticuloendothelial system for the degradation of hemoglobin vesicles (artificial oxygen carriers) after massive intravenous doses by daily repeated infusions for 14 days. J Pharmacol Exp Ther 311:874-884. (Pubitemid 39612691)
6. Sakai H, Yuasa M, Onuma H, Takeoka S, Tsuchida E. (2000) Synthesis and physicochemical characterization of a series of hemoglobin-based oxygen carriers: objective comparison between cellular and acellular types. Bioconjug Chem 11:56-64. (Pubitemid 30063344)
7. Vandegriff KD, McCarthy M, Rohlfs RJ, Winslow RM. (1997) Colloid osmotic properties of modified hemoglobins: chemically cross-linked versus polyethylene glycol surfaceconjugated. Biophys Chem 69:23-30. (Pubitemid 28010759)
8. Sakai H, Sato A, Takeoka S, Tsuchida E. (2007) Rheological properties of hemoglobin vesicles (artificial oxygen carriers) suspended in a series of plasma-substitute solutions. Langmuir 23:8121-8128. (Pubitemid 47155325)
9. Sakai H, Suzuki Y, Kinoshita M, Takeoka S, Maeda N, Tsuchida E. (2003) O2 release from Hb vesicles evaluated using an artificial, narrow O2-permeable tube: comparison with RBCs and acellular Hbs. Am J Physiol Heart Circ Physiol 285:H2543-H2551 (Pubitemid 37443072)
10. Sakai H, Sato A, Masuda K, Takeoka S, Tsuchida E. (2008) Encapsulation of concentrated hemoglobin solution in phospholipid vesicles retards the reaction with NO, but not CO, by intracellular diffusion barrier. J Biol Chem 283:1508-1517
11. Sakai H, Masada Y, Horinouchi H, Yamamoto M, Ikeda E, Takeoka S, Kobayashi K, Tsuchida E. (2004) Hemoglobin-vesicles suspended in recombinant human serum albumin for resuscitation from hemorrhagic shock in anesthetized rats. Crit Care Med 32:539-545. (Pubitemid 38234138)
12. Sakai H, Horinouchi H, Tsuchida E, Kobayashi K. (2009) Hemoglobin-vesicles and red blood cells as carriers of carbon monoxide prior to oxygen for resuscitation from hemorrhagic shock in a rat model. Shock 31(5):507-514.