Difficulties in selecting an appropriate neonatal thyroid stimulating hormone (TSH) screening threshold

Archives of Disease in Childhood

Volumn 95, Issue 3, 2010, Pages 169-173

  Korada, Srinivasa Murthy ^a   Pearce, Mark ^a   Ward Platt, Martin P ^b   Avis, Enid ^b   Turner, Steve ^b   Wastell, Hilary ^b   Cheetham, Tim ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b ROYAL VICTORIA INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

THYROTROPIN;

ARTICLE; BLOOD EXAMINATION; CONGENITAL HYPOTHYROIDISM; CONTROLLED STUDY; HEALTH SURVEY; HUMAN; INFANT; MAJOR CLINICAL STUDY; NEWBORN; NEWBORN SCREENING; NORMAL VALUE; PRIORITY JOURNAL; THYROTROPIN BLOOD LEVEL;

BIOLOGICAL MARKERS; CONGENITAL HYPOTHYROIDISM; GREAT BRITAIN; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; NEONATAL SCREENING; PROFESSIONAL PRACTICE; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; THYROTROPIN; THYROXINE;

EID: 77949895491     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/adc.2008.147884     Document Type: Article

References (17)

1. Department of Health and Social Security (DHSS). Joint Standing Committee on Screening in Medical Care. Screening for Early Detection of Congenital Hypothyroidism. HN(81)20. London: DHSS, 1981.
2. Dubuis JM, Glorieux J, Richer F, et al. Outcome of severe congenital hypothyroidism: closing the developmental gap with early high dose levothyroxine treatment. J Clin Endocrinol Metab 1996;81:222-7.
3. Bongers-Schokking JJ, de Muinck Keizer-Schrama SM. Influence of timing and dose of thyroid hormone replacement on mental, psychomotor, and behavioral development in children with congenital hypothyroidism. J Pediatr 2005;147:768-74.
4. UK Newborn Screening Programme Centre. http://newbornbloodspot. screening.nhs.uk/standards (accessed 8 January 2010).
5. Pryce RA, Gregory JW, Warner JT, et al. Is the current threshold level for screening for congenital hypothyroidism too high? An audit of the clinical evaluation, confirmatory diagnostic tests and treatment of infants with increased blood spot thyroid-stimulating hormone concentrations identified on newborn blood spot screening in Wales. Arch Dis Child 2007;92:1048.
6. Alm J, Hagenfeldt L, Larsson A, et al. Incidence of congenital hypothyroidism: retrospective study of neonatal laboratory screening versus clinical symptoms as indicators leading to diagnosis. Br Med J (Clin Res Ed) 1984;289:1171-5.
7. Korada M, Pearce MS, Ward Platt MP, et al. Repeat testing for congenital hypothyroidism in preterm infants is unnecessary with an appropriate thyroid stimulating hormone threshold. Arch Dis Child Fetal Neonatal Ed 2008;93:F286-8.
8. Moreno JC, Bikker H, Kempers MJ, et al. Inactivating mutations in the gene for thyroid oxidase 2 (THOX2) and congenital hypothyroidism. N Engl J Med 2002;347:95-102.
9. Daliva AL, Linder B, DiMartino-Nardi J, et al. Three-year follow-up of borderline congenital hypothyroidism. J Pediatr 2000;136:53-6.
10. Calaciura F, Motta RM, Miscio G, et al. Subclinical hypothyroidism in early childhood: a frequent outcome of transient neonatal hyperthyrotropinemia. J Clin Endocrinol Metab 2002;87:3209-14.
11. Ahmed SF, Barnes ND, Hughes IA. Initial evaluation of congenital hypothyroidism: a survey of general paediatricians in East Anglia. Arch Dis Child 1997;77:339-41.
12. Jones JH, Mackenzie J, Croft GA, et al. Improvement in screening performance and diagnosis of congenital hypothyroidism in Scotland 1979-2003. Arch Dis Child 2006;91:680-5.
13. Perry RJ, Maroo S, Maclennan AC, et al. Combined ultrasound and isotope scanning is more informative in the diagnosis of congenital hypothyroidism than single scanning. Arch Dis Child 2006;91:972-6.
14. Hall SK, Hutchesson AC, Kirk JM. Congenital hypothyroidism, seasonality and consanguinity in the West Midlands, England. Acta Paediatr 1999;88:212-15.
15. Hall D, Elliman D. Health for all children. 4th edn. Oxford, UK: Oxford University Press, 2003.
16. Williams FL, Simpson J, Delahunty C, et al. Developmental trends in cord and postpartum serum thyroid hormones in preterm infants. J Clin Endocrinol Metab 2004;89:5314-20.
17. American Academy of Pediatrics. Update of newborn screening and therapy for congenital hypothyroidism. Pediatrics 2006;117:2290- 303.