EMD 57033 partially reverses ventilator-induced diaphragm muscle fibre calcium desensitisation

Pflugers Archiv European Journal of Physiology

Volumn 459, Issue 3, 2010, Pages 475-483

  Ochala, Julien ^a   Radell, Peter J ^b   Eriksson, Lars I ^b   Larsson, Lars ^a,c  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Ca 2+ activation; Ca2+ sensitizer; Diaphragm muscle; Mechanical ventilation; Porcine model; Skinned fibre

Indexed keywords

5 [1 (3,4 DIMETHOXYBENZOYL) 1,2,3,4 TETRAHYDRO 6 QUINOLYL] 3,6 DIHYDRO 6 METHYL 2H 1,3,4 THIADIAZIN 2 ONE; CALCIUM ION; ACTIN; CALCIUM; MYOSIN; PHOSPHODIESTERASE INHIBITOR; QUINOLINE DERIVATIVE; THIADIAZINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CELL ACTIVATION; CONTROLLED STUDY; DIAPHRAGM MUSCLE; DRUG EFFICACY; DRUG MECHANISM; FEMALE; MUSCLE CELL; MUSCLE CONTRACTION; MUSCLE DISEASE; MUSCLE FORCE; MUSCLE FUNCTION; MUSCLE STIFFNESS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; VENTILATOR INDUCED LUNG INJURY; ANIMAL; CYTOLOGY; DIAPHRAGM; DRUG EFFECT; HUMAN; METABOLISM; PHYSIOLOGY; RANDOMIZATION; SKELETAL MUSCLE; SWINE; VENTILATOR;

ACTINS; ANIMALS; CALCIUM; DIAPHRAGM; FEMALE; HUMANS; MUSCLE CONTRACTION; MUSCLE FIBERS, SKELETAL; MYOSINS; PHOSPHODIESTERASE INHIBITORS; QUINOLINES; RANDOM ALLOCATION; SWINE; THIADIAZINES; VENTILATORS, MECHANICAL;

EID: 77949886069     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-009-0744-1     Document Type: Article

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