Germ plasm-like Dot cells maintain their wound regenerative function after in vitro expansion

Clinical and Experimental Pharmacology and Physiology

Volumn 37, Issue 4, 2010, Pages

  Kong, Wuyi ^a   Li, Shaowei ^a   Lorenz, H Peter ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Germ plasm like Dot cells; Stem cells; Tissue regeneration; VASA; Wound healing

Indexed keywords

CELL MARKER; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN VASA; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; BONE MARROW; CELL EXPANSION; CELL FUNCTION; CELL GROWTH; CELL REGENERATION; CELL RENEWAL; CELL STRUCTURE; CELL TRANSPLANTATION; CONTROLLED STUDY; DOT CELL; EMBRYONIC STEM CELL; EPITHELIUM CELL; EPITHELIZATION; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GERM CELL; GERMPLASM; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; MALE; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; PROTEIN EXPRESSION; SKIN CELL; WILD TYPE; WOUND HEALING;

ADULT STEM CELLS; ANIMALS; ANTIGENS, SURFACE; BLOOD CELLS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SEPARATION; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; EMBRYONIC STEM CELLS; FEMALE; GERM CELLS; MALE; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; REGENERATION; SKIN; SKIN PHYSIOLOGICAL PHENOMENA; SPHEROIDS, CELLULAR; STEM CELLS; TIME FACTORS; WOUND HEALING;

EID: 77949881588     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2010.05343.x     Document Type: Article

References (33)

1. Kloc M, Larabell C, Chan AP, Etkin LD. Contribution of METRO pathway localized molecules to the organization of the germ cell lineage. Mech. Dev. 1998 75 : 81 93.
2. Kobayashi S, Amikura R, Okada M. Localization of mitochondrial large rRNA in germinal granules and the consequent segregation of germ line. Int. J. Dev. Biol. 1994 38 : 193 199.
3. Beams HW, Kessel RG. Cytokinesis: a comparative study of cytoplasmic division in animal cells. Am. Sci. 1976 64 : 279 290.
4. Mahowald AP. Germ plasm revisited and illuminated. Science 1992 255 : 1216 1217.
5. Eddy EM. Germ plasm and the differentiation of the germ cell line. Int. Rev. Cytol. 1975 43 : 229 280.
6. Chang CC, Dearden P, Akam M. Germ line development in the grasshopper Schistocerca gregaria: Vasa as a marker. Dev. Biol. 2002 252 : 100 118.
7. Hay B, Jan LY, Jan YN. Localization of vasa, a component of Drosophila polar granules, in maternal-effect mutants that alter embryonic anteroposterior polarity. Development 1990 109 : 425 433.
8. Tadros W, Lipshitz HD. Setting the stage for development: mRNA translation and stability during oocyte maturation and egg activation in Drosophila. Dev. Dyn. 2005 232 : 593 608.
9. Shizuru JA, Negrin RS, Weissman IL. Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system. Annu. Rev. Med. 2005 56 : 509 538.
10. Wagers AJ, Christensen JL, Weissman IL. Cell fate determination from stem cells. Gene Ther. 2002 9 : 606 612.
11. Ferrari G, Cusella-De Angelis G et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science 1998 279 : 1528 1530.
12. Mezey E, Chandross KJ, Harta G, Maki RA, McKercher SR. Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science 2000 290 : 1779 1782.
13. Lagasse E, Connors H, Al-Dhalimy M et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat. Med. 2000 6 : 1229 1234.
14. Sata M, Saiura A, Kunisato A et al. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat. Med. 2002 8 : 403 409.
15. Wagers AJ, Sherwood RI, Christensen JL, Weissman IL. Little evidence for developmental plasticity of adult hematopoietic stem cells. Science 2002 297 : 2256 2259.
16. Balsam LB, Wagers AJ, Christensen JL, Kofidis T, Weissman IL, Robbins RC. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature 2004 428 : 668 673.
17. Roybon L, Ma Z, Asztely F et al. Failure of transdifferentiation of adult hematopoietic stem cells into neurons. Stem Cells 2006 24 : 1594 1604.
18. Jiang Y, Jahagirdar BN, Reinhardt RL et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002 418 : 41 9.
19. D'Ippolito G, Diabira S, Howard GA, Menei P, Roos BA, Schiller PC. Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential. J. Cell Sci. 2004 117 : 2971 2981.
20. Kucia M, Reca R, Campbell FR et al. A population of very small embryonic-like (VSEL) CXCR4(+)SSEA-1(+)Oct-4+ stem cells identified in adult bone marrow. Leukemia 2006 20 : 857 869.
21. Kucia M, Halasa M, Wysoczynski M et al. Morphological and molecular characterization of novel population of CXCR4+ SSEA-4+ Oct-4+ very small embryonic-like cells purified from human cord blood: preliminary report. Leukemia 2007 21 : 297 303.
22. Muller T, Fleischmann G, Eildermann K et al. A novel embryonic stem cell line derived from the common marmoset monkey (Callithrix jacchus) exhibiting germ cell-like characteristics. Hum. Reprod. 2009 24 : 1359 1372.
23. Sacco A, Doyonnas R, Kraft P, Vitorovic S, Blau HM. Self-renewal and expansion of single transplanted muscle stem cells. Nature 2008 456 : 502 506.
24. Chiavegato A, Bollini S, Pozzobon M et al. Human amniotic fluid-derived stem cells are rejected after transplantation in the myocardium of normal, ischemic, immuno-suppressed or immuno-deficient rat. J. Mol. Cell. Cardiol. 2007 42 : 746 759.
25. Holden C. Stem cells. Controversial marrow cells coming into their own? Science 2007 315 : 760 761.
26. Kong W, Li S, Longaker MT, Lorenz HP. Blood-derived small Dot cells reduce scar in wound healing. Exp. Cell Res. 2008 314 : 1529 1539.
27. Yu J, Vodyanik MA, Smuga-Otto K et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007 318 : 1917 1920.
28. Takahashi K, Tanabe K, Ohnuki M et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007 131 : 861 872.
29. Styhler S, Nakamura A, Swan A, Suter B, Lasko P. Vasa is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst development. Development 1998 125 : 1569 1578.
30. Lorand-Metze I, Califani SM, Ribeiro E, Lima CS, Metze K. The prognostic value of maturation-associated phenotypic abnormalities in myelodysplastic syndromes. Leuk. Res. 2008 32 : 211 213.
31. Mohle R, Bautz F, Rafii S, Moore MA, Brugger W, Kanz L. The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1. Blood 1998 91 : 4523 4530.
32. Lapidot T, Dar A, Kollet O. How do stem cells find their way home? Blood 2005 106 : 1901 1910.
33. Furlani D, Ugurlucan M, Ong L et al. Is the intravascular administration of mesenchymal stem cells safe? Microvasc. Res. 2009 77 : 370 376.