Naofen, a novel WD40-repeat protein, mediates spontaneous and tumor necrosis factor-induced apoptosis

Biochemical and Biophysical Research Communications

Volumn 394, Issue 1, 2010, Pages 153-157

  Feng, Guo Gang ^a   Li, Chang ^b   Huang, Lei ^a   Tsunekawa, Koji ^a   Sato, Yuko ^a   Fujiwara, Yoshihiro ^a   Komatsu, Tooru ^a   Honda, Takashi ^c   Fan, Jun Hua ^c   Goto, Hidemi ^c   Koide, Tatsuro ^d   Hasegawa, Takaaki ^a   Ishikawa, Naohisa ^a  

^a AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Heping District Center for Disease Control and Preven   (China)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d AICHI GAKUIN UNIVERSITY   (Japan)

Author keywords

Apoptosis; Caspase; siRNA; TNF ; WD40 repeat domain

Indexed keywords

CASPASE 3; DIPEPTIDE; MESSENGER RNA; NAOFEN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VEROTOXIN 2;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA LIBRARY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CELL LINE; ENZYME ACTIVATION; HUMANS; PROTEINS; RATS; RATS, WISTAR; RNA, MESSENGER; TISSUE DISTRIBUTION; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 77949874995     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.02.133     Document Type: Article

References (16)

1. Neer E.J., Schmidt C.J., Nambudripad R., and Smith T.F. The ancient regulatory-protein family of WD-repeat proteins. Nature 371 (1994) 297-300
2. Smith T.F., Gaitatzes C., Saxena K., and Neer E.J. The WD repeat: a common architecture for diverse functions. Science 24 (1999) 181-185
3. Lambright D.G., Sondek J., Bohm A., Skiba N.P., Hamm H.E., and Sigler P.B. The 2.0 A crystal structure of a heterotrimeric G protein. Nature 379 (1996) 311-319
4. Sondek J., Bohm A., Lambright D.G., Hamm H.E., and Sigler P.B. Crystal structure of a G-protein beta gamma dimer at 2.1 A resolution. Nature 379 (1996) 369-374
5. Smith T.F., Gaitatzes C., Saxena K., and Neer E.J. The WD repeat: a common architecture for diverse functions. Trends Biochem. Sci. 24 (1999) 181-185
6. Cain K., Brown D.G., Langlais C., and Cohen G.M. Caspase activation involves the formation of aposome, a large (approximately 700 kDa) caspase-activating complex. J. Biol. Chem. 274 (1999) 22686-22692
7. Saeki M., Irie Y., Ni L., Yoshida M., Itsuki Y., and Kamisaki Y. Monad, a WD repeat protein, promotes apoptosis induced by TNF-alpha. Biochem. Biophys. Res. Commun. 342 (2006) 568-572
8. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 (2001) 402-408
9. Liu Z.G., Hsu H., Goeddel D.V., and Karin M. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death. Cell 87 (1996) 565-576
10. Srinivasula S.M., Ahmad M., Fernandes-Alnemri T., and Alnemri E.S. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol. Cell 1 (1998) 949-957
11. Foster G.H., Armstrong C.S., Sakiri R., and Tesh V.L. Shiga toxin-induced tumor necrosis factor alpha expression: requirement for toxin enzymatic activity and monocyte protein kinase C and protein tyrosine kinases. Infect. Immun. 68 (2000) 5183-5189
12. Nakamura A., Johns E.J., Imaizumi A., Yanagawa Y., and Kohsaka T. Activation of beta(2)-adrenoceptor prevents shiga toxin 2-induced TNF-alpha gene transcription. J. Am. Soc. Nephrol. 12 (2001) 2288-2299
13. Lee J.E., Kim J.S., Choi I.H., Tagawa M., Kohsaka T., and Jin D.K. Cytokine expression in the renal tubular epithelial cells stimulated by Shiga toxin 2 of Escherichia coli O157:H7. Ren. Fail. 24 (2002) 567-575
14. Kiyokawa N., Taguchi T., Mori T., Uchida H., Sato N., Takeda T., and Fujimoto J. Induction of apoptosis in normal human renal tubular epithelial cells by Escherichia coli Shiga toxins 1 and 2. J. Infect. Dis. 178 (1998) 178-184
15. Creydt V.P., Silberstein C., Zotta E., and Ibarra C. Cytotoxic effect of Shiga toxin-2 holotoxin and its B subunit on human renal tubular epithelial cells. Microbes Infect. 8 (2006) 410-419
16. Feng G.G., Yamada M., Wongsawatkul O., Li C., Huang L., An J., Komatsu T., Fujiwara Y., and Ihsikawa N. Role of naofen, a novel WD repeat-containing protein, in reducing nitric oxide-induced relaxation. Clini. Exp. Pharma. Physiol. 35 (2008) 1447-1453