Rhodium-catalyzed complete regioselective lntermolecular cross-cyclotrimerization of aryl ethynyl ethers and nitriles or isocyanates at room temperature

Organic Letters

Volumn 12, Issue 6, 2010, Pages 1312-1315

  Komine, Yoshiyuki ^a   Tanaka, Ken ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINAP, 2 NAPHTHOL; BINAP, 2-NAPHTHOL; ETHER DERIVATIVE; ISOCYANIC ACID DERIVATIVE; NAPHTHALENE DERIVATIVE; NITRILE; ORGANOMETALLIC COMPOUND; PYRIDINE DERIVATIVE; PYRIDONE DERIVATIVE; RHODIUM;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; STEREOISOMERISM; SYNTHESIS; TEMPERATURE;

CATALYSIS; CYCLIZATION; ETHERS; ISOCYANATES; MOLECULAR STRUCTURE; NAPHTHALENES; NITRILES; ORGANOMETALLIC COMPOUNDS; PYRIDINES; PYRIDONES; RHODIUM; STEREOISOMERISM; TEMPERATURE;

EID: 77949831892     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol100182u     Document Type: Article

References (27)

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11. Other regioisomers were generated in <5% yields. A crosscyclotrimerization product of one molecule of 3a and two molecules of 4 was not detected at all.
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26. Homo-cyclotrimerization products of 3a-e were generated as byproducts in the reactions of Tables 1-3.
27. Although the slow addition of aryl ethynyl ether 3a to nitrile 6a or isocyanate 8a and the Rh catalyst over 30 min was also examined, the yields of the corresponding pyridine 7aa and 2-pyridone 9aa. were not increased.