Association between endothelial function and chronotropic incompetence in subjects with chronic heart failure receiving optimal medical therapy

Echocardiography

Volumn 27, Issue 3, 2010, Pages 294-299

  Vittorio, Timothy J ^a   Lanier, Gregg ^a   Zolty, Ronald ^b   Sarswat, Nitasha ^b   Tseng, Chi Hong ^c   Colombo, Paolo C ^d   Jorde, Ulrich P ^d  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d NewYork Presbyterian Hospital   (United States)

Author keywords

Brachial artery; Chronotropic incompetence; Dilated cardiomyopathy; Flow mediated dilatation; Heart failure

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARVEDILOL; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METOPROLOL SUCCINATE; SPIRONOLACTONE;

ADULT; AGE DISTRIBUTION; AGED; ARTERY BLOOD FLOW; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; BRACHIAL ARTERY; CARDIAC PATIENT; CARDIOPULMONARY EXERCISE TEST; CHRONOTROPISM; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENDOTHELIAL DYSFUNCTION; EXERCISE TOLERANCE; FEMALE; HEART FAILURE; HEART FUNCTION; HEART RATE VARIABILITY; HUMAN; INTRAVASCULAR ULTRASOUND; MALE; PRIORITY JOURNAL; PROGNOSIS; ECHOGRAPHY; HEART FUNCTION TEST; MIDDLE AGED; PATHOPHYSIOLOGY; VASCULAR ENDOTHELIUM;

ADULT; AGED; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; BRACHIAL ARTERY; ENDOTHELIUM, VASCULAR; EXERCISE TOLERANCE; FEMALE; HEART FAILURE; HEART FUNCTION TESTS; HUMANS; MALE; MIDDLE AGED; PROGNOSIS;

EID: 77949707005     PISSN: 07422822     EISSN: 15408175     Source Type: Journal    
DOI: 10.1111/j.1540-8175.2009.01011.x     Document Type: Article

References (46)

1. Park JB, Charbonneau F, Schiffrin EL : Correlation of endothelial function in large and small arteries in human essential hypertension. J Hypertens 2001 19 : 415 420.
2. Zhang X, Zhao SP, Li XP, et al : Endothelium-dependent and -independent functions are impaired in patients with coronary heart disease. Atherosclerosis 2000 149 : 19 24.
3. Rundek T, Hundle R, Ratchford E, et al : Endothelial dysfunction is associated with carotid plaque: A cross-sectional study from the population based Northern Manhattan Study. BMC Cardiovasc Disord 2006 6 : 35.
4. Mizia-Stec K, Gasior Z, Mizia M, et al : Flow-mediated dilation and gender in patients with coronary artery disease: Arterial size influences gender differences in flow-mediated dilation. Echocardiography 2007 24 : 1051 1057.
5. Gullu H, Erdogan D, Caliskan M, et al : Interrelationship between noninvasive predictors of atherosclerosis: Transthoracic coronary flow reserve, flow-mediated dilation, carotid intima-media thickness, aortic stiffness, aortic distensibility, elastic modulus, and brachial artery diameter. Echocardiography 2006 23 : 835 842.
6. Meeking DR, Cummings MH, Thorne S, et al : Endothelial dysfunction in Type 2 diabetic subjects with and without microalbuminuria. Diabet Med 1999 16 : 841 847.
7. Yu Y, Suo L, Yu H, et al : Insulin resistance and endothelial dysfunction in type 2 diabetes patients with or without microalbuminuria. Diabetes Res Clin Pract 2004 65 : 95 104.
8. Kubo SH, Rector TS, Bank AJ, et al : Endothelium-dependent vasodilation is attenuated in patients with heart failure. Circulation 1991 84 : 1589 1596.
9. Patel AR, Kuvin JT, Pandian NG, et al : Heart failure etiology affects peripheral vascular endothelial function after cardiac transplantation. J Am Coll Cardiol 2001 37 : 195 200.
10. Katz SD, Biasucci L, Sabba C, et al : Impaired endothelium-mediated vasodilation in the peripheral vasculature of patients with congestive heart failure. J Am Coll Cardiol 1992 19 : 918 925.
11. Katz SD, Hryniewicz K, Hriljac I, et al : Vascular endothelial dysfunction and mortality risk in patients with chronic heart failure. Circulation 2005 111 : 310 314.
12. Fischer D, Rossa S, Landmesser U, et al : Endothelial dysfunction in patients with chronic heart failure is independently associated with increased incidence of hospitalization, cardiac transplantation, or death. Eur Heart J 2005 26 : 65 69.
13. Meyer B, Mortl D, Strecker K, et al : Flow-mediated vasodilation predicts outcome in patients with chronic heart failure: Comparison with B-type natriuretic peptide. J Am Coll Cardiol 2005 46 : 1011 1018.
14. Bank AJ, Lee PC, Kubo SH. Endothelial dysfunction in patients with heart failure: Relationship to disease severity. J Card Fail 2000 6 : 29 36.
15. Drexler H, Hayoz D, Munzel T, et al : Endothelial function in chronic congestive heart failure. Am J Cardiol 1992 69 : 1596 1601.
16. Just H, Drexler H, Hasenfuss G : Pathophysiology and treatment of congestive heart failure. Cardiology 1994 84 (Suppl 2 99 107.
17. Giannattasio C, Achilli F, Grappiolo A, et al : Radial artery flow-mediated dilatation in heart failure patients: Effects of pharmacological and nonpharmacological treatment. Hypertension 2001 38 : 1451 1455.
18. Melzer C, Bohm M, Bondke HJ, et al : Chronotropic incompetence in patients with an implantable cardioverter defibrillator: Prevalence and predicting factors. Pacing Clin Electrophysiol 2005 28 : 1025 1031.
19. Colucci WS, Ribeiro JP, Rocco MB, et al : Impaired chronotropic response to exercise in patients with congestive heart failure. Role of postsynaptic beta-adrenergic desensitization. Circulation 1989 80 : 314 323.
20. Katritsis D, Camm AJ : Chronotropic incompetence: a proposal for definition and diagnosis. Br Heart J 1993 70 : 400 402.
21. Jorde UP, Vittorio TJ, Kasper ME, et al : Chronotropic incompetence, beta-blockers, and functional capacity in advanced congestive heart failure: Time to pace? Eur J Heart Fail 2008 10 : 96 101.
22. Erbs S, Linke A, Gielen S, et al : Exercise training in patients with severe chronic heart failure: Impact on left ventricular performance and cardiac size. A retrospective analysis of the Leipzig Heart Failure Training Trial. Eur J Cardiovasc Prev Rehabil 2003 10 : 336 344.
23. van Tol BA, Huijsmans RJ, Kroon DW, et al : Effects of exercise training on cardiac performance, exercise capacity and quality of life in patients with heart failure: A meta-analysis. Eur J Heart Fail 2006 8 : 841 850.
24. Corretti MC, Plotnick GD, Vogel RA : Technical aspects of evaluating brachial artery vasodilatation using high-frequency ultrasound. Am J Physiol 1995 268 : H1397 H404.
25. Wu HD, Katz SD, Beniaminovitz A, et al : Assessment of endothelium-mediated vasodilation of the peripheral circulation by transcutaneous ultrasonography and venous occlusion plethysmography. Heart Vessels 1999 14 : 143 148.
26. Corretti MC, Anderson TJ, Benjamin EJ, et al : Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: A report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 2002 39 : 257 265.
27. Vittorio TJ, Zolty R, PK G : Interdependence of cardiac and endothelial function in patients with symptomatic chronic heart failure of nonischemic etiology. Echocardiography 2009 May 29 [Epub ahead of print UP, Vittorio TJ, Dimayuga CA, et al : Comparison of suppression of the circulating and vascular renin-angiotensin system by enalapril versus trandolapril in chronic heart failure. Am J Cardiol 2004 94 : 1501 1505.
28. Berger R, Stanek B, Hulsmann M, et al : Effects of endothelin a receptor blockade on endothelial function in patients with chronic heart failure. Circulation 2001 103 : 981 986.
29. Simova I, Nossikoff A, Denchev S : Interobserver and intraobserver variability of flow-mediated vasodilatation of the brachial artery. Echocardiography 2008 25 : 77 83.
30. Bots ML, Westerink J, Rabelink TJ, et al : Assessment of flow-mediated vasodilatation (FMD) of the brachial artery: effects of technical aspects of the FMD measurement on the FMD response. Eur Heart J 2005 26 : 363 368.
31. Ellis GR, Anderson RA, Lang D, et al : Neutrophil superoxide anion-generating capacity, endothelial function and oxidative stress in chronic heart failure: effects of short- and long-term vitamin C therapy. J Am Coll Cardiol 2000 36 : 1474 1482.
32. Neuberg GW, Friedman SH, Weiss MB, et al : Cardiopulmonary exercise testing. The clinical value of gas exchange data. Arch Intern Med 1988 148 : 2221 2226.
33. Astrand I : Aerobic work capacity in men and women with special reference to age. Acta Physiol Scand Suppl 1960 49 : 1 92.
34. Clarkson P, Celermajer DS, Powe AJ, et al : Endothelium-dependent dilatation is impaired in young healthy subjects with a family history of premature coronary disease. Circulation 1997 96 : 3378 3383.
35. Huang PH, Leu HB, Chen JW, et al : Comparison of endothelial vasodilator function, inflammatory markers, and N-terminal pro-brain natriuretic peptide in patients with or without chronotropic incompetence to exercise test. Heart 2006 92 : 609 614.
36. Hijmering ML, Stroes ES, Olijhoek J, et al : Sympathetic activation markedly reduces endothelium-dependent, flow-mediated vasodilation. J Am Coll Cardiol 2002 39 : 683 688.
37. Thijssen DH, de Groot P, Kooijman M, et al : Sympathetic nervous system contributes to the age-related impairment of flow-mediated dilation of the superficial femoral artery. Am J Physiol Heart Circ Physiol 2006 291 : H3122 H3129.
38. Ghiadoni L, Donald AE, Cropley M, et al : Mental stress induces transient endothelial dysfunction in humans. Circulation 2000 102 : 2473 2478.
39. Hornig B, Arakawa N, Haussmann D, et al : Differential effects of quinaprilat and enalaprilat on endothelial function of conduit arteries in patients with chronic heart failure. Circulation 1998 98 : 2842 2848.
40. Hornig B, Arakawa N, Drexler H : Effect of ACE inhibition on endothelial dysfunction in patients with chronic heart failure. Eur Heart J 1998 19 (Suppl G G48 G53.
41. Matsuda Y, Akita H, Terashima M, et al : Carvedilol improves endothelium-dependent dilatation in patients with coronary artery disease. Am Heart J 2000 140 : 753 759.
42. Hambrecht R, Hilbrich L, Erbs S, et al : Correction of endothelial dysfunction in chronic heart failure: Additional effects of exercise training and oral L-arginine supplementation. J Am Coll Cardiol 2000 35 : 706 713.
43. Hambrecht R, Fiehn E, Weigl C, et al : Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation 1998 98 : 2709 2715.
44. Hornig B, Maier V, Drexler H : Physical training improves endothelial function in patients with chronic heart failure. Circulation 1996 93 : 210 214.
45. Keteyian SJ, Brawner CA, Schairer JR, et al : Effects of exercise training on chronotropic incompetence in patients with heart failure. Am Heart J 1999 138 : 233 240.
46. Gademan MG, Swenne CA, Verwey HF, et al : Effect of exercise training on autonomic derangement and neurohumoral activation in chronic heart failure. J Card Fail 2007 13 : 294 303.