The anatomical basis for a novel classification of osteoarthritis and allied disorders

Journal of Anatomy

Volumn 216, Issue 3, 2010, Pages 279-291

  McGonagle, Dennis ^a   Tan, Ai Lyn ^a   Carey, John ^b   Benjamin, Michael ^c  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b Merlin Park University Hospital   (Ireland)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Bone; Cartilage; Classification; Ligaments; Osteoarthritis

Indexed keywords

ALLOPURINOL;

ARTICLE; ARTICULAR CARTILAGE; CHONDROPATHY; CLINICAL FEATURE; DISEASE CLASSIFICATION; DISEASE SEVERITY; FUNCTIONAL ANATOMY; HUMAN; IMAGE ANALYSIS; JOINT PROSTHESIS; KNEE MENISCUS; LIGAMENT DISEASE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOARTHRITIS; PATHOGENESIS; PATHOLOGICAL ANATOMY; PRIORITY JOURNAL; REGENERATIVE MEDICINE; SYNOVITIS;

BONE AND BONES; CARTILAGE, ARTICULAR; HUMANS; JOINTS; LIGAMENTS; MAGNETIC RESONANCE IMAGING; OSTEOARTHRITIS;

EID: 77949678912     PISSN: 00218782     EISSN: 14697580     Source Type: Journal    
DOI: 10.1111/j.1469-7580.2009.01186.x     Document Type: Article

References (106)

1. Aagaard H, Verdonk R. Function of the normal meniscus and consequences of meniscal resection. Scand J Med Sci Sports 1999, 9:134-140.
2. Adams JG, McAlindon T, Dimasi M. Contribution of meniscal extrusion and cartilage loss to joint space narrowing in osteoarthritis. Clin Radiol 1999, 54:502-506.
3. Agarwala S, Jain D, Joshi VR. Efficacy of alendronate, a bisphosphonate, in the treatment of AVN of the hip. A prospective open-label study. Rheumatology (Oxford) 2005, 44:352-359.
4. Anderson DD, Brown TD, Radin EL. The influence of basal cartilage calcification on dynamic juxtaarticular stress transmission. Clin Orthop Relat Res 1993, 298-307.
5. Bellamy N, Kirwan J, Boers M. Recommendations for a core set of outcome measures for future phase III clinical trials in knee, hip, and hand osteoarthritis. Consensus development at OMERACT III. J Rheumatol 1997, 24:799-802.
6. Benjamin M, McGonagle D. The anatomical basis for disease localisation in seronegative spondyloarthropathy at entheses and related sites. J Anat 2001, 199:503-526.
7. Benjamin M, McGonagle D. Histopathologic changes at " synovio-entheseal complexes" suggesting a novel mechanism for synovitis in osteoarthritis and spondylarthritis. Arthritis Rheum 2007, 56:3601-3609.
8. Benjamin M, Moriggl B, Brenner E. The " enthesis organ" concept: why enthesopathies may not present as focal insertional disorders. Arthritis Rheum 2004a, 50:3306-3313.
9. Benjamin M, Redman S, Milz S. Adipose tissue at entheses: the rheumatological implications of its distribution. A potential site of pain and stress dissipation? Ann Rheum Dis 2004b, 63:1549-1555.
10. Bhattacharyya T, Gale D, Dewire P. The clinical importance of meniscal tears demonstrated by magnetic resonance imaging in osteoarthritis of the knee. J Bone Joint Surg Am 2003, 85-A:4-9.
11. Birrell F, Arden NK. A view on the pathogenesis of osteoarthritis from the shoulders of giants. Rheumatology (Oxford) 2008, 47:1263-1264.
12. Blankenbaker DG, De Smet AA, Fine JP. Is intra-articular pathology associated with MCL edema on MR imaging of the non-traumatic knee? Skeletal Radiol 2005, 34:462-467.
13. Blom AB, Brockbank SM, van Lent PL. Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1. Arthritis Rheum 2009, 60:501-512.
14. Blumenkrantz G, Majumdar S. Quantitative magnetic resonance imaging of articular cartilage in osteoarthritis. Eur Cell Mater 2007, 13:76-86.
15. Boutry N, Paul C, Leroy X. Rapidly destructive osteoarthritis of the hip: MR imaging findings. AJR Am J Roentgenol 2002, 179:657-663.
16. Brandt KD, Radin EL, Dieppe PA. Yet more evidence that osteoarthritis is not a cartilage disease. Ann Rheum Dis 2006, 65:1261-1264.
17. Brandt KD, Dieppe P, Radin EL. Etiopathogenesis of osteoarthritis. Rheum Dis Clin North Am 2008, 34:531-559.
18. Buckwalter JA, Brown TD. Joint injury, repair, and remodeling: roles in post-traumatic osteoarthritis. Clin Orthop Relat Res 2004, 7-16.
19. Burr DB. The importance of subchondral bone in the progression of osteoarthritis. J Rheumatol Suppl 2004, 70:77-80.
20. Choi JW, Chung HW, Ahn JH. Central hole tear of the discoid meniscus of the knee in magnetic resonance imaging: mimicking the bucket-handle tear. J Comput Assist Tomogr 2009, 33:155-159.
21. Clark JM. The structure of vascular channels in the subchondral plate. J Anat 1990, 171:105-115.
22. Conaghan P. Is MRI useful in osteoarthritis? Best Pract Res Clin Rheumatol 2006, 20:57-68.
23. Davies DV. The structure and functions of the synovial membrane. Br Med J 1950, 1:92-95.
24. Day JS, Ding M, van der Linden JC. A decreased subchondral trabecular bone tissue elastic modulus is associated with pre-arthritic cartilage damage. J Orthop Res 2001, 19:914-918.
25. Dequeker J. The relationship between osteoporosis and osteoarthritis. Clin Rheum Dis 1985, 11:271-296.
26. Englund M, Lohmander LS. Risk factors for symptomatic knee osteoarthritis fifteen to twenty-two years after meniscectomy. Arthritis Rheum 2004, 50:2811-2819.
27. Ericsson YB, Tjornstrand J, Tiderius CJ. Relationship between cartilage glycosaminoglycan content (assessed with dGEMRIC) and OA risk factors in meniscectomized patients. Osteoarth Cartil 2009, 17:565-570.
28. Fan H, Liu H, Wong EJ. In vivo study of anterior cruciate ligament regeneration using mesenchymal stem cells and silk scaffold. Biomaterials 2008, 29:3324-3337.
29. Felson DT, McLaughlin S, Goggins J. Bone marrow edema and its relation to progression of knee osteoarthritis. Ann Intern Med 2003, 139:330-336.
30. Felson DT, Gross KD, Nevitt MC. The effects of impaired joint position sense on the development and progression of pain and structural damage in knee osteoarthritis. Arthritis Rheum 2009, 61:1070-1076.
31. Franchi A, Bullough PG. Secondary avascular necrosis in coxarthrosis: a morphologic study. J Rheumatol 1992, 19:1263-1268.
32. Garnero P, Aronstein WS, Cohen SB. Relationships between biochemical markers of bone and cartilage degradation with radiological progression in patients with knee osteoarthritis receiving risedronate: the Knee Osteoarthritis Structural Arthritis randomized clinical trial. Osteoarth Cartil 2008, 16:660-666.
33. Gelse K, von der Mark K, Aigner T. Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells. Arthritis Rheum 2003, 48:430-441.
34. Gold GE, Burstein D, Dardzinski B. MRI of articular cartilage in OA: novel pulse sequences and compositional/functional markers. Osteoarth Cartil 2006, 14(Suppl A):A76-A86.
35. Goldring MB. Anticytokine therapy for osteoarthritis. Expert Opin Biol Ther 2001, 1:817-829.
36. Grainger AJ, Farrant JM, O'Connor PJ. MR imaging of erosions in interphalangeal joint osteoarthritis: is all osteoarthritis erosive? Skeletal Radiol 2007, 36:737-745.
37. Greenstein AS, Marzo-Ortega H, Emery P. Magnetic resonance imaging as a predictor of progressive joint destruction in neuropathic joint disease. Arthritis Rheum 2002, 46:2814-2815.
38. Grunke M, Schulze-Koops H. Successful treatment of inflammatory knee osteoarthritis with tumour necrosis factor blockade. Ann Rheum Dis 2006, 65:555-556.
39. Grynpas MD, Alpert B, Katz I. Subchondral bone in osteoarthritis. Calcif Tissue Int 1991, 49:20-26.
40. Guilak F, Fermor B, Keefe FJ. The role of biomechanics and inflammation in cartilage injury and repair. Clin Orthop Relat Res 2004, 17-26.
41. Haywood L, McWilliams DF, Pearson CI. Inflammation and angiogenesis in osteoarthritis. Arthritis Rheum 2003, 48:2173-2177.
42. Hernandez-Molina G, Guermazi A, Niu J. Central bone marrow lesions in symptomatic knee osteoarthritis and their relationship to anterior cruciate ligament tears and cartilage loss. Arthritis Rheum 2008, 58:130-136.
43. Herrak P, Gortz B, Hayer S. Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis. Arthritis Rheum 2004, 50:2327-2337.
44. Hill CL, Seo GS, Gale D. Cruciate ligament integrity in osteoarthritis of the knee. Arthritis Rheum 2005, 52:794-799.
45. Hudelmaier M, Glaser C, Hohe J. Age-related changes in the morphology and deformational behavior of knee joint cartilage. Arthritis Rheum 2001, 44:2556-2561.
46. Hunter DJ, Zhang YQ, Niu JB. The association of meniscal pathologic changes with cartilage loss in symptomatic knee osteoarthritis. Arthritis Rheum 2006, 54:795-801.
47. Hunter DJ, Lo GH, Gale D. The reliability of a new scoring system for knee osteoarthritis MRI and the validity of bone marrow lesion assessment: BLOKS (Boston Leeds Osteoarthritis Knee Score). Ann Rheum Dis 2008, 67:206-211.
48. Imhof H, Breitenseher M, Kainberger F. Degenerative joint disease: cartilage or vascular disease? Skeletal Radiol 1997, 26:398-403.
49. Jones EA, English A, Henshaw K. Enumeration and phenotypic characterization of synovial fluid multipotential mesenchymal progenitor cells in inflammatory and degenerative arthritis. Arthritis Rheum 2004, 50:817-827.
50. Jones EA, Crawford A, English A. Synovial fluid mesenchymal stem cells in health and early osteoarthritis: detection and functional evaluation at the single-cell level. Arthritis Rheum 2008, 58:1731-1740.
51. Jude EB, Selby PL, Burgess J. Bisphosphonates in the treatment of Charcot neuroarthropathy: a double-blind randomised controlled trial. Diabetologia 2001, 44:2032-2037.
52. Juni P, Dieppe P, Donovan J. Population requirement for primary knee replacement surgery: a cross-sectional study. Rheumatology (Oxford) 2003, 42:516-521.
53. Juras V, Bittsansky M, Majdisova Z. In vitro determination of biomechanical properties of human articular cartilage in osteoarthritis using multi-parametric MRI. J Magn Reson 2009, 197:40-47.
54. Keen HI, Wakefield RJ, Grainger AJ. An ultrasonographic study of osteoarthritis of the hand: synovitis and its relationship to structural pathology and symptoms. Arthritis Rheum 2008, 59:1756-1763.
55. Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957, 16:494-502.
56. Kiani C, Chen L, Wu YJ. Structure and function of aggrecan. Cell Res 2002, 12:19-32.
57. Kimura M, Miyazawa K, Tabuchi M. Bisphosphonate treatment increases the size of the mandibular condyle and normalizes growth of the mandibular ramus in osteoprotegerin-deficient mice. Calcif Tissue Int 2008, 82:137-147.
58. Konttinen YT, Tiainen VM, Gomez-Barrena E. Innervation of the joint and role of neuropeptides. Ann N Y Acad Sci 2006, 1069:149-154.
59. Kornaat PR, Ceulemans RY, Kroon HM. MRI assessment of knee osteoarthritis: Knee Osteoarthritis Scoring System (KOSS) - inter-observer and intra-observer reproducibility of a compartment-based scoring system. Skeletal Radiol 2005, 34:95-102.
60. Koshino T, Wada S, Ara Y. Regeneration of degenerated articular cartilage after high tibial valgus osteotomy for medial compartmental osteoarthritis of the knee. Knee 2003, 10:229-236.
61. Krasnokutsky S, Attur M, Palmer G. Current concepts in the pathogenesis of osteoarthritis. Osteoarth Cartil 2008, 16(Suppl 3):S1-S3.
62. Lanzer WL, Komenda G. Changes in articular cartilage after meniscectomy. Clin Orthop Relat Res 1990, 41-48.
63. Loeser RF. Molecular mechanisms of cartilage destruction: mechanics, inflammatory mediators, and aging collide. Arthritis Rheum 2006, 54:1357-1360.
64. Loeuille D, Chary-Valckenaere I, Champigneulle J. Macroscopic and microscopic features of synovial membrane inflammation in the osteoarthritic knee: correlating magnetic resonance imaging findings with disease severity. Arthritis Rheum 2005, 52:3492-3501.
65. Lories RJ. Joint homeostasis, restoration, and remodeling in osteoarthritis. Best Pract Res Clin Rheumatol 2008, 22:209-220.
66. Louboutin H, Debarge R, Richou J. Osteoarthritis in patients with anterior cruciate ligament rupture: a review of risk factors. Knee 2009, 16:239-244.
67. Magnano MD, Chakravarty EF, Broudy C. A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands. J Rheumatol 2007, 34:1323-1327.
68. McDermott ID, Amis AA. The consequences of meniscectomy. J Bone Joint Surg Br 2006, 88:1549-1556.
69. McDougall JJ, Andruski B, Schuelert N. Unravelling the relationship between age, nociception and joint destruction in naturally occurring osteoarthritis of Dunkin Hartley guinea pigs. Pain 2009, 141:222-232.
70. McGonagle D, De Bari C, Arnold P. Lessons from musculoskeletal stem cell research: the key to successful regenerative medicine development. Arthritis Rheum 2007a, 56:714-721.
71. McGonagle D, Lories RJ, Tan AL. The concept of a " synovio-entheseal complex" and its implications for understanding joint inflammation and damage in psoriatic arthritis and beyond. Arthritis Rheum 2007b, 56:2482-2491.
72. McGonagle D, Tan AL, Grainger AJ. Heberden's nodes and what Heberden could not see: the pivotal role of ligaments in the pathogenesis of early nodal osteoarthritis and beyond. Rheumatology (Oxford) 2008, 47:1278-1285.
73. McGonagle D, Tan AL, Moller Dohn U. Microanatomic studies to define predictive factors for the topography of periarticular erosion formation in inflammatory arthritis. Arthritis Rheum 2009, 60:1042-1051.
74. Messner K, Gao J. The menisci of the knee joint. Anatomical and functional characteristics, and a rationale for clinical treatment. J Anat 1998, 193(Pt 2):161-178.
75. Molloy ES, Morgan MP, Doherty GA. Mechanism of basic calcium phosphate crystal-stimulated cyclo-oxygenase-1 up-regulation in osteoarthritic synovial fibroblasts. Rheumatology (Oxford) 2008, 47:965-971.
76. Oegema TR, Carpenter RJ, Hofmeister F. The interaction of the zone of calcified cartilage and subchondral bone in osteoarthritis. Microsc Res Tech 1997, 37:324-332.
77. Ozkoc G, Circi E, Gonc U. Radial tears in the root of the posterior horn of the medial meniscus. Knee Surg Sports Traumatol Arthrosc 2008, 16:849-854.
78. Peterfy CG, Guermazi A, Zaim S. Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis. Osteoarth Cartil 2004, 12:177-190.
79. Quasnichka HL, Anderson-MacKenzie JM, Tarlton JF. Cruciate ligament laxity and femoral intercondylar notch narrowing in early-stage knee osteoarthritis. Arthritis Rheum 2005, 52:3100-3109.
80. Radin EL, Rose RM. Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop Relat Res 1986, 34-40.
81. Radin EL, Paul IL, Rose RM. Role of mechanical factors in pathogenesis of primary osteoarthritis. Lancet 1972, 1:519-522.
82. Ralston SH, Langston AL, Reid IR. Pathogenesis and management of Paget's disease of bone. Lancet 2008, 372:155-163.
83. Raudenbush D, Sumner DR, Panchal PM. Subchondral thickness does not vary with cartilage degeneration on the metatarsal. J Am Podiatr Med Assoc 2003, 93:104-110.
84. Recnik G, Kralj-Iglic V, Iglic A. The role of obesity, biomechanical constitution of the pelvis and contact joint stress in progression of hip osteoarthritis. Osteoarth Cartil 2009, 17:879-882.
85. Reginato AJ. Calcium pyrophosphate dihydrate gout and other crystal deposition diseases. Curr Opin Rheumatol 1991, 3:676-683.
86. Roos EM, Dahlberg L. Positive effects of moderate exercise on glycosaminoglycan content in knee cartilage: a four-month, randomized, controlled trial in patients at risk of osteoarthritis. Arthritis Rheum 2005, 52:3507-3514.
87. Rose DM, Sydlaske AD, Agha-Babakhani A. Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils. Arthritis Rheum 2006, 54:3363-3371.
88. Ryan TM, Ketcham RA. Angular orientation of trabecular bone in the femoral head and its relationship to hip joint loads in leaping primates. J Morphol 2005, 265:249-263.
89. Scher C, Craig J, Nelson F. Bone marrow edema in the knee in osteoarthrosis and association with total knee arthroplasty within a three-year follow-up. Skeletal Radiol 2008, 37:609-617.
90. Schiphof D, Boers M, Bierma-Zeinstra SM. Differences in descriptions of Kellgren and Lawrence grades of knee osteoarthritis. Ann Rheum Dis 2008a, 67:1034-1036.
91. Schiphof D, de Klerk BM, Koes BW. Good reliability, questionable validity of 25 different classification criteria of knee osteoarthritis: a systematic appraisal. J Clin Epidemiol 2008b, 61:1205-1215.
92. Seedhom BB. Conditioning of cartilage during normal activities is an important factor in the development of osteoarthritis. Rheumatology (Oxford) 2006, 45:146-149.
93. Steklov N, Srivastava A, Sung KL. Aging-related differences in chondrocyte viscoelastic properties. Mol Cell Biomech 2009, 6:113-119.
94. Tan AL, Grainger AJ, Tanner SF. High-resolution magnetic resonance imaging for the assessment of hand osteoarthritis. Arthritis Rheum 2005, 52:2355-2365.
95. Tan AL, Grainger AJ, Tanner SF. A high-resolution magnetic resonance imaging study of distal interphalangeal joint arthropathy in psoriatic arthritis and osteoarthritis: are they the same? Arthritis Rheum 2006a, 54:1328-1333.
96. Tan AL, Toumi H, Benjamin M. Combined high-resolution magnetic resonance imaging and histological examination to explore the role of ligaments and tendons in the phenotypic expression of early hand osteoarthritis. Ann Rheum Dis 2006b, 65:1267-1272.
97. Tanamas S, Hanna FS, Cicuttini FM. Does knee malalignment increase the risk of development and progression of knee osteoarthritis? A systematic review. Arthritis Rheum 2009, 61:459-467.
98. Tiderius CJ, Olsson LE, Leander P. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in early knee osteoarthritis. Magn Reson Med 2003, 49:488-492.
99. Toncheva A, Remichkova M, Ikonomova K. Inflammatory response in patients with active and inactive osteoarthritis. Rheumatol Int 2009, 29:1197-1203.
100. Vlychou M, Koutroumpas A, Malizos K. Ultrasonographic evidence of inflammation is frequent in hands of patients with erosive osteoarthritis. Osteoarth Cartil 2009, 17:1283-1287.
101. de Vries-Bouwstra JK, Dijkmans BA, Breedveld FC. Biologics in early rheumatoid arthritis. Rheum Dis Clin North Am 2005, 31:745-762.
102. Weinberger A. Gout, uric acid metabolism, and crystal-induced inflammation. Curr Opin Rheumatol 1995, 7:359-363.
103. Weng LH, Wang CJ, Ko JY. Inflammation induction of Dickkopf-1 mediates chondrocyte apoptosis in osteoarthritic joint. Osteoarth Cartil 2009, 17:919-929.
104. van der Weyden L, Wei L, Luo J. Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol 2006, 169:515-527.
105. Yamasaki T, Deie M, Shinomiya R. Transplantation of meniscus regenerated by tissue engineering with a scaffold derived from a rat meniscus and mesenchymal stromal cells derived from rat bone marrow. Artif Organs 2008, 32:519-524.
106. Yeow CH, Cheong CH, Ng KS. Anterior cruciate ligament failure and cartilage damage during knee joint compression: a preliminary study based on the porcine model. Am J Sports Med 2008, 36:934-942.