Ependymoma in Adults: Surgery, Reoperation and Radiotherapy for Survival

Pathology and Oncology Research

Volumn 16, Issue 1, 2010, Pages 93-99

  Vitanovics, Dusan ^a   Bálint, Katalin ^a   Hanzély, Zoltán ^a   Banczerowski, Péter ^a   Áfra, Dénes ^a  

^a NATIONAL INSTITUTE OF NEUROSURGERY   (Hungary)

Author keywords

Adult ependymoma; Radiotherapy; Reoperation; Surgery

Indexed keywords

CARMUSTINE;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; EPENDYMOMA; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PHOTON THERAPY; POSTOPERATIVE PERIOD; PROGNOSIS; RADIATION DOSE; REOPERATION; TUMOR LOCALIZATION;

ADOLESCENT; ADULT; AGED; BRAIN NEOPLASMS; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; EPENDYMOMA; FEMALE; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; NEUROSURGICAL PROCEDURES; RADIOTHERAPY; REOPERATION; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 77949659553     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12253-009-9194-5     Document Type: Article

References (54)

1. M Reni G Gatta E Mazza Ch Vecht 2007 Ependymoma Crit Rev Oncol/Hematol 63 81 89 10.1016/j.critrevonc.2007.03.004 (Pubitemid 46810282)
2. Burger PSB (1994) Tumors of the central nervous system: vol. fascicle 10. D.C. Armed Forces Institute of Pathology, Washington D.C
3. HW Chin JJ Hazel TH Kim C Freeman Y Maruyama 1984 Intracranial ependymomas and ependymoblastomas Strahlentherapie 160 191 194 1:STN:280:DyaL2c3isVyktw%3D%3D 6729860
4. GJ Dohrmann JR Farwell JT Flannery 1976 Ependymomas and ependymoblastomas in children J Neurosurg 45 273 283 10.3171/jns.1976.45.3.0273 1:STN:280:DyaE283jvFyhtw%3D%3D 948014
5. Louis DN, Ohgaki H, Wiestler OD, Canevee WK (2007) WHO classification of tumours of the central nervous system. International Agency for Research on Cancer, Lyon
6. D Schiffer A Chio MT Giordana A Migheli L Palma B Pollo R Soffietti A Triboli 1991 Histologic prognostic factors in ependymoma Childs Nerv Syst 7 177 182 10.1007/BF00249392 1:STN:280:DyaK38%2FjsVOrtw%3D%3D 1933913
7. A Metellus M Barrie D Figarella-Branger O Chinot R Giorgi J Gouvernet A Jouvet J Guyotat 2007 Multicentric French study on adult intracranial ependymomas: prognostic factors analysis and therapeutic considerations from a cohort of 152 patients Brain 130 1338 1349 10.1093/brain/awm046 17449478 (Pubitemid 47355950)
8. D Afra W Muller F Slowik O Wilcke H Budka L Turoczy 1983 Supratentorial lobar ependymomas: reports on the grading and survival periods in 80 cases, including 46 recurrences Acta Neurochir [Wien] 69 243 251 10.1007/BF01401811 1:STN:280:DyaL2c%2Fns1Gnsw%3D%3D
9. MP McLaughlin RB Marcus Jr JM Buatti WM McCollough JP Mickle A Kedar BL Maria RR Lillion 1998 Ependymoma: results, prognostic factors and treatment recommendations Int J Radiat Oncol Biol Phys 40 845 850 10.1016/S0360-3016(97) 00893-6 1:STN:280:DyaK1c7ovFymtQ%3D%3D 9531369 (Pubitemid 28150802)
10. PC Gerszten IF Pollack AJ Martinez KH Lo J Janosky AL Albright 1996 Intracranial ependymomas of childhood. Lack of correlation of histopathology and clinical outcome Pathol Res Pract 192 515 522 1:STN:280:DyaK2s%2FhtVGquw%3D%3D 8857637
11. D Figarella-Branger M Civatte C Bouvier-Labit J Gouvernet D Gambarelli JC Gentet G Lena M Choux JF Pellissier 2000 Prognostic factors in intracranial ependymomas in children J Neurosurg 93 605 611 10.3171/jns.2000.93.4.0605 1:STN:280:DC%2BD3cvmt1CrtQ%3D%3D 11014538
12. MK Lyons PJ Kelly 1991 Posterior fossa ependymomas: report of 30 cases and review of the literature Neurosurgery 28 659 664 10.1097/00006123-199105000- 00004 1:STN:280:DyaK3MzktlSqug%3D%3D 1876243
13. JE Marks SJ Adler 1982 A comparative study of ependymomas by site of origin Int J Radiat Oncol Biol Phys 8 37 43 1:STN:280:DyaL387ktFOltA%3D%3D 7061255
14. M Choux JF Pellissier 2000 Prognostic factors in intracranial ependymomas in children J Neurosurg 93 605 613 10.3171/jns.2000.93.4.0605 11014538
15. A Korshunov A Golanov R Sycheva V Timirgaz 2007 The histologic grade is a main prognostic factor for patients with intracranial ependymomas treated in the microneurosurgical era: an analysis of 258 patients Cancer 100 1230 1237 10.1002/cncr.20075
16. B Timmermann RD Kortmann J Kuhl N Willich M Bamberg 2002 Die interdisziplinäre Therapie von Ependymomen im Kindesalter Strahlenther Onkol. 178 469 479 10.1007/s00066-002-0971-2 12426832
17. GW Ross LJ Rubinstein 1989 Lack of histopathological correlation of malignant ependymomas with postoperative survival J Neurosurg 70 31 36 10.3171/jns.1989.70.1.0031 1:STN:280:DyaL1M%2FotVygtw%3D%3D 2909684
18. M Preusser S Wolfsberger T Czech I Budka H Slave JA Hainfellner 2005 Survivin expression in intracranial ependymomas and its correlation with tumor cell proliferation and patient outcome Am J Clin Pathol. 124 543 549 10.1309/PP2G5GAAFKV82DTG 1:CAS:528:DC%2BD2MXhtFChsbbK 16146813
19. RA Prayson 1999 Clinicopathologic study of 61 patients with ependymoma including MIB-1 immunohistochemistry Ann Diagn Pathol 3 11 18 10.1016/S1092-9134(99)80004-5 1:STN:280:DyaK1M7ksFKmtg%3D%3D 9990108
20. S Wolfsberger I Fischer R Hoftberger P Birner I Slavc K Dieckmann T Czech H Budka J Hainfellner 2004 Ki-67 immunolabeling index is an accurate predictor of outcome in patients with intracranial ependymoma Am J Surg Pathol 28 914 920 10.1097/00000478-200407000-00011 15223962 (Pubitemid 38856848)
21. D Figarella-Branger D Gambarelli C Dollo B Devictor AM Perez-Castillo L Genitori G Lena 1991 Infratentorial ependymomas of childhood. Correlation between histological features, immunohistological phenotype, silver nucleolar organizer region staining values and post-operative survival in 16 cases Acta Neuropathol [Berl] 82 208 216 10.1007/BF00294447 1:STN:280: DyaK38%2FisVyrug%3D%3D
22. S Shuangshoti EJ Rushing H Mena C Olsen GD Sandberg 2005 Supratentorial extraventricular ependymal neoplasms: a clinicopathological study of 32 patients Cancer 103 2598 2605 10.1002/cncr.21111 15861411 (Pubitemid 40800540)
23. O Onguru B Kurt O Gunhan F Soylemezoglu 2006 Cyclooxigenase-2 (cox-2) expression and angiogenesis in intracranial ependymomas Clin Neuropath 25 06 20
24. Ch Teo P Nakaji P Symons V Tobias R Cohn R Smee 2003 Ependymoma Childs Nerv Syst 19 270 285 10.1007/s00381-003-0753-x 12761644 (Pubitemid 36869196)
25. E Kaplan P Meier 1958 Nonparametric estimation from incomplete observation J Am Stat Assoc 53 457 481 10.2307/2281868
26. DR Cox 1972 Regression models and life-tables J R Stat Soc B34 187 220
27. L Casentini F Gullotta U Möhrer 1981 Clinical and morphological investigations on ependymomas and their tissue cultures Neurochirurgia 24 51 58 1:STN:280:DyaL3M7ntlejsQ%3D%3D 7219656
28. J Guyotat F Signorelli S Desme D Frappaz G Madarassy MF Montange 2002 Intracranial ependymomas in adult patients: analyses of prognostic factors J Neurooncol 60 255 268 10.1023/A:1021136029072 1:STN:280:DC%2BD3s%2FgsVOmtA%3D%3D 12510777 (Pubitemid 35439180)
29. LJ Vanuytsel EM Bessell SE Ashley HJ Bloom M Brada 1992 Intracranial ependymoma: long-term results of a policy of surgery and radiotherapy Int J Radiat Oncol Biol Phys 23 313 319 1:STN:280:DyaK383mslyqsw%3D%3D 1587752
30. TR Merchant JJ Jenkins PC Burger RA Sanford SH Sherwood D Jones-Wallace RL Heideman SJ Thompson KJ Helton LK Kun 2002 Influence of tumor grade on time to progression after irradiation for localized ependymoma in children J Radiation Oncology Biol Phys 53 52 57 10.1016/S0360-3016(01)02801-2 (Pubitemid 34465807)
31. M Rosenblum 1998 Ependymal tumors: a review of their diagnostic surgical pathology Pediatr Neurosurg 28 160 165 10.1159/000028641 1:STN:280: DyaK1czntV2iuw%3D%3D 9705595
32. TH Schwartz S Kim RS Glick E Bagiella C Balmaceda MR Fetell BH Stein MB Sisti JN Bruce 1999 Supratentorial ependymomas in adult patients Neurosurgery 44 721 731 10.1097/00006123-199904000-00018 1:STN:280:DyaK1M3hsFCkuw%3D%3D 10201296
33. SJ Mork AC Loken 1977 Ependymoma:a follow-up study of 101 cases Cancer 40 907 915 10.1002/1097-0142(197708)40:2<907::AID-CNCR2820400247>3.0.CO;2-2 1:STN:280:DyaE2s3ktlyktg%3D%3D 890671
34. GB Nazar HJ Hoffman LE Becker D Jenkin RP Humphreys EB Hendrick 1990 Infratentorial ependymomas in childhood: prognostic factors and treatment J Neurosurg 72 408 417 10.3171/jns.1990.72.3.0408 1:STN:280:DyaK3c7lsFClsg%3D%3D 2303876
35. R Schroder C Ploner RI Ernestus 1993 The growth potential of ependymomas with varying grades of malignancy measured by the Ki-67 labelling index and mitotic index Neurosurg Rev 16 145 150 10.1007/BF00258248 1:STN:280: DyaK3szkslyhsA%3D%3D 8345908
36. Schulz MD CCW, Zinninger GF, Tefft M (1968) Radiotherapy of intracranial neoplasms. With a special section on radiotherapeutic management of central nervous system tumors in children. In: Krayenbühl HMP, Sweet WH (eds) Progress In Neurological Surgery, 2nd edn. Karger S, Basel New York, pp 319-370
37. SA Leibel GE Sheline 1987 Radiation therapy for neoplasms of the brain J Neurosurg 66 1 22 10.3171/jns.1987.66.1.0001 1:STN:280:DyaL2s%2FmtVSgtA%3D%3D 3023563
38. B Donahue A Steinfeld 1998 Intracranial ependymoma in the adult parient:Succesful treatment with surgery and radiotherapy J Neuro-Oncology 37 131 133 10.1023/A:1005965328104 1:STN:280:DyaK1c7ot1altA%3D%3D (Pubitemid 28073585)
39. OM Salazar P Rubin D Bassano VA Marcial 1975 Improved survival of patients with intracranial ependymomas by irradiation: dose selection and field extension Cancer 35 1563 1573 10.1002/1097-0142(197506)35:6<1563::AID- CNCR2820350614>3.0.CO;2-I 1:STN:280:DyaE2M3gslWiug%3D%3D 1148991
40. AC Paulino BC Wen 2000 The significance of radiotherapy treatment duration in intracranial ependymoma Int J Radiat Oncol Biol Phys 47 585 589 10.1016/S0360-3016(99)00535-0 1:STN:280:DC%2BD3c3pvVKrug%3D%3D 10837939 (Pubitemid 30317474)
41. P Schuller U Schafer O Micke N Willich 1999 Radiotherapy for intracranial and spinal ependymomas. A retrospective analysis Strahlenther Onkol 175 105 111 10.1007/BF02742343 1:STN:280:DyaK1M7ptlGksA%3D%3D 10093612
42. EG Shaw RG Evans BW Scheithauer DM Ilstrup JD Earle 1987 Postoperative radiotherapy of intracranial ependymoma in pediatric and adult patients Int J Radiat Oncol Biol Phys 13 1457 1462 1:STN:280:DyaL2szgslGksg%3D%3D 3624024
43. W Wagner P Schuller N Willich O Schober S Palkovic C Morgenroth P Bartenstein FJ Prott U Niewohner 1995 Intraoperative radiotherapy [IORT] in malignant brain tumors Strahlenther Onkol 171 154 164 1:STN:280: DyaK2M3isVKlsQ%3D%3D 7709332
44. MJ Verstegen DA Bosch D Troost 1997 Treatment of ependymomas. Clinical and non-clinical factors influencing prognosis: a review Br J Neurosurg 11 542 553 10.1080/02688699745709 1:STN:280:DC%2BD3cvmtleitQ%3D%3D 11013626 (Pubitemid 28017987)
45. K Ikezaki T Matsushima T Inoue N Yokoyama Y Kaneko M Fukui 1993 Correlation of microanatomical localization with postoperative survival in posterior fossa ependymomas Neurosurgery 32 38 44 10.1097/00006123-199301000- 00006 1:STN:280:DyaK3s7jtlCjug%3D%3D 8421555
46. SE Schild K Nisi BW Scheithauer WW Wong MK Lyons PJ Schomberg, et al. 1947 The results of radiotherapy for ependymomas: the Mayo Clinic experience Int J Radiat Oncol Biol Phys 42 958
47. IF Pollack PC Gerszten AJ Martinez KH Lo B Shultz AL Albright, et al. 1995 Intracranial ependymomas of childhood: long-term outcome and prognostic factors Neurosurgery 37 655 666 1:STN:280:DyaK287hslaisA%3D%3D 8559293
48. CR West DA Bruse PK Duffner 1985 Ependymomas: factors in clinical and diagnostic staging Cancer 56 1812 1816 10.1002/1097-0142(19851001)56:7+<1812: :AID-CNCR2820561319>3.0.CO;2-1 1:STN:280:DyaL2M3ot1SlsA%3D%3D 4027918
49. EA Healey PD Barnes WJ Kupsky RM Scott SE Sallan PM Black NJ Tarbell 1991 The prognostic significance of postoperative residual tumor in ependymoma Neurosurgery 28 666 671 10.1097/00006123-199105000-00005 1:STN:280: DyaK3MzktlSquw%3D%3D 1876244
50. J Hukin F Epstein D Lefton J Allen 1998 Treatment of intracranial ependymoma by surgery alone Pediat Neurosurg 29 40 45 10.1159/000028683 1:STN:280:DyaK1cvivFCnsw%3D%3D (Pubitemid 29060798)
51. PI Robertson PM Zeltzer JM Boyett LB Rorke JC Allen JR Geyer P Stanly Li Hao AL Albright P McGuire-Cullen JL Finley KL Stevensjr JL Milstein RJ Packer J Wisoff and the ChildrenCancer Group 1998 Survival and prognostic factors following radiation therapy and chemotherapy for ependymomas in Chidren's Cancer Group J Neurosurg 88 695 703 10.3171/jns.1998.88.4.0695 1:STN:280: DyaK1c7osVKhuw%3D%3D 9525716
52. J Palma P Celli A Mariottini A Zalaffi G Schettini 2000 The importance of surgery in supratentorial ependymomas Long-term survival in a series of 23 cases Child Nerv Syst 16 170 175 10.1007/s003810050487 1:STN:280: DC%2BD3c3mtFWqug%3D%3D
53. JJ Kovalic N Flaris PW Grigsby M Pirkowski JR Simpson KA Roth 1993 Intracranial ependymoma long term outcome, patterns of failure J Neurooncol 15 125 131 10.1007/BF01053933 1:STN:280:DyaK3s3os1KmsQ%3D%3D 8509817
54. R Schroder H Stutzer N Klug 1996 Prognostic relevance of localization and grading in intracranial ependymomas of childhood Childs Nerv Syst 12 522 526 8906366