Cyclooxygenase-2 (Cox-2) expression and angiogenesis in intracranial ependymomas

Clinical Neuropathology

Volumn 25, Issue 5, 2006, Pages 216-220

  Onguru, O ^a   Kurt, B ^a   Gunhan, O ^a   Soylemezoglu, F ^b  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Angiogenesis; Cyclooxygenase 2; Ependymomas; Ki 67 labeling index

Indexed keywords

CYCLOOXYGENASE 2; KI 67 ANTIGEN; PROSTAGLANDIN;

ADOLESCENT; ADULT; ANAPLASTIC CARCINOMA; ANGIOGENESIS; ARTICLE; BRAIN DAMAGE; CANCER INVASION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; EPENDYMOMA; FEMALE; GLIOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; MALE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; TUMOR GROWTH; VASCULARIZATION;

ADOLESCENT; ADULT; BRAIN NEOPLASMS; CELL PROLIFERATION; CHILD; CHILD, PRESCHOOL; CYCLOOXYGENASE 2; EPENDYMOMA; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; KI-67 ANTIGEN; MALE; NEOVASCULARIZATION, PATHOLOGIC; TUMOR MARKERS, BIOLOGICAL;

EID: 33748762786     PISSN: 07225091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Folkman J. What is the evidence that tumors are angiogenesis-dependent? J Natl Cancer Inst. 1990; 82: 4-6.
2. Hansen S, Grabau DA, Rose C, Bak M, Sorensen FB. Angiogenesis in breast cancer: a comparative study of the observer variability of methods for determining microvessel density. Lab Invest. 1998; 75: 1563-1573.
3. Hara A, Okayasu I. Cyclooxygenase-2 and inducible nitric oxide synthase expression in human astrocytic gliomas: correlation with angiogenesis and prognostic significance. Acta Neuropathol (Berl). 2004; 108: 43-48.
4. Kim SK, Lim SY, Wang KC, Kim YY, Chi JG, Choi YL, Shin HJ, Cho BK. Overexpressionofcyclooxygenase-2 in childhood ependymomas: role of Cox-2 inhibitor in growth and multi-drug resistance in vitro. Oncol Rep. 2004; 12: 403-409.
5. Kleihues P, Cavenee W. World Health Organization classification of tumors: pathology and genetics of tumors of the nervous system. Lyon: IARC Press; 2000.
6. Majima M, Amano H, Hayashi I. Angiogenic and prostaglandin. Folia Pharmacol Jpn. 2001; 117: 283-292.
7. Matsuo M, Yonemitsu N, Zaitsu M, Ishii K, Hamasaki Y, Fukuyama K, Tabuchi K, Miyazaki S. Expression of prostaglandin H synthase-2 in human brain tumors. Acta Neuropathol (Berl). 2001; 102: 181-187.
8. Prayson RA. Clinicopathologic study of 61 patients with ependymoma including MIB-1 immunohistochemistry. Ann Diagn Pathol. 1999; 3: 11-18.
9. Tsuji M, Kawano S, Tsuji S, Sawaoka H, Hori M, DuBois R. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell. 1998; 93: 705-716.